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1161
Respiratory syncytial virus vaccination in older adults and patients with chronic disorders: A position paper from the Portuguese Society of Pulmonology, the Portuguese Association...
Published 2025-12-01“…Background Respiratory syncytial virus (RSV) is an important cause of lower respiratory tract infection, hospitalisation and death in adults.Methods Based on evidence regarding the impact of RSV on adult populations at risk for severe infection and the efficacy and safety of RSV vaccines, the Portuguese Society of Pulmonology, the Portuguese Association of General and Family Medicine, the Portuguese Society of Cardiology, the Portuguese Society of Infectious Diseases and Clinical Microbiology, the Portuguese Society of Endocrinology, Diabetes and Metabolism, and the Portuguese Society of Internal Medicine endorses this position paper with recommendations to prevent RSV-associated disease and its complications in adults through vaccination.Conclusion The RSV vaccine is recommended for people aged ≥50 years with risk factors (chronic obstructive pulmonary disease, asthma, heart failure, coronary artery disease, diabetes, chronic kidney disease, chronic liver disease, immunocompromise, frailty, dementia, and residence in a nursing home) and all persons aged ≥60 years. …”
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1162
PreS1 deletions in genotype C HBV leads to severe hepatic inflammation and hepatocarcinogenesis via the IRE1-JNK axis
Published 2025-03-01“…We investigated the mechanism by which preS1Del is related to liver disease progression and enhanced HBV replication, focusing on endoplasmic reticulum (ER) stress. …”
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1163
The Diagnosis Is in the Smear: A Case and Review of Spur Cell Anemia in Cirrhosis
Published 2021-01-01“…We present the case of a 57-year-old woman with alcoholic cirrhosis who presented with symptomatic macrocytic anemia with a hemoglobin level of 7.4 g/dL and signs of decompensated liver disease. Notably, she had no signs of overt bleeding. …”
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1164
Reference Gene and Protein Expression Levels in Two Different NAFLD Mouse Models
Published 2020-01-01“…The aim of this work was to evaluate reference gene and protein expression in models of nonalcoholic fatty liver disease, using mice fed with a high-fat diet (HFD) and mice that are genetically obese (ob/ob). …”
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1165
Protective Effect of Thyme Extract on Albino Rats Exposed to Paraquat
Published 2022-01-01“…Paraquat (PQ), as a frequently used compound in many applications while the herbal providing is vigorously used in the curing of broad spectrum diseases such as liver disease, the influence of thyme extract or Thymus vulgaris L. …”
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1166
The Laboratory Diagnosis of Hepatitis B Virus
Published 2005-01-01“…Without intervention, approximately 15% to 40% of chronically infected individuals will eventually develop cirrhosis, end-stage liver disease or hepatocellular carcinoma, or require liver transplantation. …”
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1167
Why and How to Treat Chronic Hepatitis C
Published 2000-01-01“…In clinical practice, the decision to treat should be individualized and tailored on the basis of several virus- and host-related factors, particularly the grade and stage of liver disease, HCV genotype and levels of viremia. Appropriate monitoring of therapy by careful clinical evaluation, liver biochemistry and serumHCVRNAtesting is mandatory. …”
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1168
A Rare Cause of Ascites-Disseminated TB with Peritonitis in a Middle-Aged Female
Published 2019-01-01“…Contrast Enhanced Computed Tomography (CECT) abdomen revealed chronic liver disease with ascites. Diagnostic laparoscopy was in favour of miliary TB and the peritoneal biopsy revealed granulomatous inflammation with caseous necrosis, suggestive of TB. …”
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1169
Profile of Candida bloodstream infections among blood culture-positive patients at a tertiary care hospital
Published 2024-01-01“…The associated risk factors among patients with candidemia were diabetes (60%), chronic kidney disease (26.7%), acute respiratory distress syndrome (23.3%), chronic liver disease (23.3%), and cerebrovascular accident (16.7%). …”
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1170
Protective Effect of Thyme Extract on Albino Rats Exposed to Paraquat
Published 2022-01-01“…Paraquat (PQ), as a frequently used compound in many applications while the herbal providing is vigorously used in the curing of broad spectrum diseases such as liver disease, the influence of thyme extract or Thymus vulgaris L. …”
Get full text
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1171
Protective Effect of Thyme Extract on Albino Rats Exposed to Paraquat
Published 2022-01-01“…Paraquat (PQ), as a frequently used compound in many applications while the herbal providing is vigorously used in the curing of broad spectrum diseases such as liver disease, the influence of thyme extract or Thymus vulgaris L. …”
Get full text
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1172
Protective Effect of Thyme Extract on Albino Rats Exposed to Paraquat
Published 2022-01-01“…Paraquat (PQ), as a frequently used compound in many applications while the herbal providing is vigorously used in the curing of broad spectrum diseases such as liver disease, the influence of thyme extract or Thymus vulgaris L. …”
Get full text
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1173
The synergistic role of gut microbiota and RNA in metabolic diseases: mechanisms and therapeutic insights
Published 2025-01-01“…Dysbiosis of the gut microbiota has been linked to metabolic disorders such as type 2 diabetes, obesity, metabolic-associated fatty liver disease (MAFLD) and metabolic heart disease. Microbial metabolites, including short-chain fatty acids (SCFAs), modulate RNA expression, influencing lipid metabolism, glucose regulation, and inflammatory responses. …”
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1174
Clinical Outcomes and Quality of Life in Recipients of Livers Donated after Cardiac Death
Published 2015-01-01“…In order to examine QOL outcomes in our cohorts, we administered the Short Form Liver Disease Quality of Life questionnaire to 30 DCD and 60 DBD recipients. …”
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1175
The Burden of NAFLD and Its Characteristics in a Nationwide Population with Type 2 Diabetes
Published 2016-01-01“…We studied the prevalence of nonalcoholic fatty liver disease (NAFLD) and its clinical correlates in a population of patients with type 2 diabetes mellitus (T2DM). …”
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1176
Hepatitis B Stigma and Knowledge among Vietnamese in Ho Chi Minh City and Chicago
Published 2016-01-01“…Stigma regarding viral hepatitis and liver disease has psychological and social consequences including causing negative self-image, disrupting relationships, and providing a barrier to prevention, testing, and treatment. …”
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1177
Liver fibrosis and markers of endothelial function at metabolic syndrome and early disorders of carbohydrate metabolism
Published 2014-12-01“…Complex estimation of endothelial function at non-alcoholic fatty liver disease (NAFLD) in association with early disorders of carbohydrate metabolism, in relation to liver fibrosis severity.Material and methods. …”
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1178
Hyperuricemia-induced complications: dysfunctional macrophages serve as a potential bridge
Published 2025-01-01“…Characterized by elevated levels of UA, HUA has become an independent risk factor for gout, chronic kidney disease, insulin resistance, cardiovascular disease, nonalcoholic fatty liver disease, etc. As HUA is a metabolic syndrome, the immune response is likely to play an active role throughout the whole process. …”
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1179
Lipid-lowering Efficacy of Plant Proteins and Their Application Potential
Published 2025-01-01“…In recent years, there has been a gradual increase in the prevalence of obesity, hyperlipidaemia, coronary atherosclerosis, non-alcoholic fatty liver disease, and other conditions attributed to shifts in dietary patterns. …”
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1180
Asymptomatic Intestinal Malrotation Progressing to Midgut Volvulus in a Decompensated Alcoholic Cirrhotic Adult: A Rare Scenario Requiring Special Considerations
Published 2020-01-01“…Observation continued as his liver disease improved with alcohol cessation (Child-Pugh class A, MELD score 8). …”
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