Metabolic and Hepatic Effects of Energy-Reduced Anti-Inflammatory Diet in Younger Adults with Obesity by Gordana Kenđel Jovanović, Ines Mrakovcic-Sutic, Sandra Pavičić Žeželj, Indira Benjak Horvat, Lucia Šuša, Dario Rahelić, Sanja Klobučar Majanović

“…Associated with epidemics of obesity, nonalcoholic fatty liver disease (NAFLD) is becoming the most prevalent liver disease worldwide. …”
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The Second Canadian Symposium on Hepatitis C Virus: A Call to Action by Jason Grebely, Marc Bilodeau, Jordan J Feld, Julie Bruneau, Benedikt Fischer, Jennifer F Raven, Eve Roberts, Norma Choucha, Rob P Myers, Selena M Sagan, Joyce A Wilson, Frank Bialystok, D Lorne Tyrrell, Michael Houghton, Mel Krajden, on behalf of the National CIHR Research Training Program in Hepatitis C

“…Given that most of those already infected are aging and at risk for progressive liver disease, building research-based interdisciplinary prevention, care and treatment capacity is an urgent priority. …”
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One-year Prevalence, Comorbidities, and Cost of Hospitalizations for Alpha-1 Antitrypsin Deficiency among Patients with Chronic Obstructive Pulmonary Disease in the United States by Christopher M. Blanchette, Emily Zacherle, Joshua M. Noone, Bryce A. Van Doren, Debosree Roy, Reuben Howden

“…AATD patients were also more likely to have comorbid non-alcoholic liver disease (7% vs 2%, p<0.0001), depression (17% vs 13%, p=0.0328), and pulmonary circulation disorders (7% vs 4%, p=0.0299). …”
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The AMPK–mTOR Pathway Is Inhibited by Chaihu Shugan Powder, Which Relieves Nonalcoholic Steatohepatitis by Suppressing Autophagic Ferroptosis by Zheng Liang, Dajin Pi, Jianwei Zhen, Haizhen Yan, Chuiyang Zheng, July Liang Chen, Wen Fan, Qingliang Song, Jinyue Pan, Dongdong Liu, Maoxing Pan, Qinhe Yang, Yupei Zhang

“…Nonalcoholic steatohepatitis (NASH) is the advanced stage of nonalcoholic fatty liver disease (NAFLD), which is distinguished by the accumulation of fat in the liver, damage to liver cells, and inflammation. …”
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The Effect of Mesenchymal Stem Cell-Derived Exosomes and miR17-5p Inhibitor on Multicellular Liver Fibrosis Microtissues by Farnaz Sani, Mina Soufi Zomorrod, Negar Azarpira, Masoud Soleimani

“…Although several studies have been conducted on modeling human liver disease, it is still challenging to mimic nonalcoholic fatty liver disease in vitro. …”
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What are the lived healthcare experiences of patients with primary sclerosing cholangitis? A community-based qualitative interview study by Sheila Greenfield, Gideon Hirschfield, Jayne Parry, Katherine Arndtz, Madeline Cameron

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Unraveling the Beneficial Role of Resveratrol in Fructose-Induced Non-Alcoholic Steatohepatitis with a Focus on the AMPK/Nrf2 Signaling Axis by Soha S. Zakaria, Safaa M. Hanafy

“…<i>Background and Objectives</i>: High fructose intake is associated with non-alcoholic fatty liver disease (NAFLD), a chronic liver disease that is on the rise worldwide. …”
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Hepatocellular Carcinoma Metastasis to the Orbit in a Coinfected HIV+ HBV+ Patient Previously Treated with Orthotopic Liver Transplantation: A Case Report by S. Guerriero, G. Infante, E. Giancipoli, S. Cocchi, M. G. Fiore, D. Piscitelli, N. Cardascia

“…We report a 45-year-old male, HBV+, HIV+, with a past history of a liver transplant for ELSD (end-stage liver disease) with hepatocellular carcinoma and recurrent HCC, who presented with proptosis and diplopia of the left eye. …”
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Pathological Features of New Animal Models for Primary Biliary Cirrhosis by Koichi Tsuneyama, Yuki Moritoki, Kentaro Kikuchi, Yasuni Nakanuma

“…Primary biliary cirrhosis (PBC) is an autoimmune liver disease characterized by immune mediated biliary damage and frequent appearance of autoantibodies against mitochondrial enzymes. …”
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Granular Cell Tumour of the Bile Duct in Association with Intrahepatic Bile Duct Adenomas by F Schweiger, J Radhi, FW Coop, RW Murphy

“…The authors report the case of an asymptomatic Caucasian woman with biochemical evidence of liver disease who had a granular cell tumour of the bile duct as well as several intrahepatic bile duct adenomas.…”
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Mendelian randomization studies of risk and protective factors for osteoporosis: a systematic review and meta-analysis by Wenhao Ji, Wenhao Ji, Bin Pan, Bin Pan, Xin Chen, Xin Chen, Zhaobai Lao, Zhaobai Lao, Wanlei Yang, Wanlei Yang, Yu Qian, Yu Qian

“…The combined findings from these 30 studies revealed that rheumatoid arthritis, inflammatory bowel disease, sex hormone binding globulin, depression, non-alcoholic fatty liver disease, primary biliary cholangitis and asthma are associated with increased risk of osteoporosis, while basal metabolic rate and gut microbiota (NB1n) serves as a protective factor. …”
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Short-term Outcomes of Pancreatoduodenectomy in Patients with Liver Cirrhosis: A Systematic Review and Meta-analysis by Shahab Hajibandeh, MRCS, Shahin Hajibandeh, FRCS, Alwin Puthiyakunnel Saji, Ayman Ashabi, MRCS, Christopher Brown, FRCS, Nicholas G Mowbray, FRCS, Matthew Mortimer, FRCS, Guy Shingler, FRCS, Amir Kambal, FRCS, Bilal Al-Sarireh, FRCS, PhD

“…Whether such risks increase with the severity of the liver disease or decrease with optimization of underlying liver disease should be the focus of future research.…”
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Helicobacter mastomyrinus infection induces autoimmune hepatitis in mice by Liqi Zhu, Yuanyuan Liang, Linghan Yang, Qihui Yang, Jun Yin, Tao Wang, Xiangming Xu, Quan Zhang

“…Abstracts: Background: Autoimmune hepatitis (AIH) is a chronic progressive liver disease caused by the immune system mistakenly attacking its own hepatocytes. …”
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Antibody-induced erythrophagocyte reprogramming of Kupffer cells prevents anti-CD40 cancer immunotherapy-associated liver toxicity by Florence Vallelian, Marc Pfefferlé, Irina L Dubach, Raphael M Buzzi, Elena Dürst, Nadja Schulthess-Lutz, Livio Baselgia, Kerstin Hansen, Larissa Imhof, Sandra Koernig, Didier Le Roy, Thierry Roger, Rok Humar, Dominik J Schaer

“…This unique mode of action prevented necroinflammatory liver disease following high-dose administration of anti-CD40 mAbs. …”
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Hyperbilirubinemia: Does It Matter? by Lajos Okolicsanyi, Giulia Martina Cavestro, Claudia Guatti-Zuliani

“…Serum bilirubin concentrations are increased in several hematological and hepatic disorders; however, hyperbilirubinemia, often of familial origin, may occur without overt signs of hemolysis or evident liver disease. The authors review briefly the main steps of hepatic bilirubin metabolism, then discuss the pathogenetic mechanisms of the different forms of familial hyperbilirubinemia. …”
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MANAGEMENT OF SYNCHRONIC LARGE LIVER METASTASIS IN A NON-OCCLUSIVE COLON TUMOR by Eduardo José Brommelstroet Ramos, Hugo Pinto Marques, Martin Palavecino, Timothy Pawlik, Rene Adam, Olivier Soubrane, Paulo Herman, Ricardo Lemos Cotta-Pereira

“…Patients with no bowel occlusion and with extensive liver disease are advised neoadjuvant oncological therapy. …”
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Genetic Contribution to the Pathogenesis of Primary Biliary Cholangitis by Satoru Joshita, Takeji Umemura, Eiji Tanaka, Masao Ota

“…Formerly termed primary biliary cirrhosis, primary biliary cholangitis (PBC) is a chronic and progressive cholestatic liver disease characterized by the presence of antimitochondrial antibodies. …”
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Pregnancy Following Liver Transplantation: Review of Outcomes and Recommendations for Management by Kuljit S Parhar, Paul S Gibson, Carla S Coffin

“…Liver transplantation is considered to be the treatment of choice for end-stage liver disease and its success has led to an increase in the number of female liver transplant recipients who are of childbearing age. …”
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Autoimmune Hepatitis—Immunologically Triggered Liver Pathogenesis—Diagnostic and Therapeutic Strategies by Elisabeth Sucher, Robert Sucher, Tanja Gradistanac, Gerald Brandacher, Stefan Schneeberger, Thomas Berg

“…Autoimmune hepatitis (AIH) is a severe liver disease that arises in genetically predisposed male and female individuals worldwide. …”
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Rifampicin for Treatment of Cholestatic Pruritus Caused by Drug-Induced Acute Liver Injury as Assessed by the RUCAM Classification by Ali R. Ahmadi, Maria Chicco, Marcel van den Berge

“…The patient had no history of liver disease and no risk factors for viral hepatitis. …”
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