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601
Allium cepa L. as a natural antioxidant: Its efficacy in combating heat stress-induced physiological alterations
Published 2025-03-01“…However, the positive benefits of AC were partially diminished in the HS + AC group, perhaps due to the severe oxidative stress caused by heat stress (HS).This study highlights the probable potential of AC as a natural antioxidant in modifying heat stress-induced oxidative damage, hematological changes, and lipid metabolism disruptions; however, its protective effects are insufficient to mitigate heat stress. …”
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602
Perbedaan Profil Lipid pada Akseptor Depo Medroksi Progesteron Asetat dengan Implant Levonorgestrel di Wilayah Kerja Puskesmas Air Tawar Padang Tahun 2014
Published 2015-01-01“…<br />Kata kunci: profil lipid, depo medroksiprogesteron asetat, implant levonorgestrel</p><p>Abstract<br />Depo Medroxyprogesterone Acetate and Levonorgestrel Implants are synthetic progestine hormonal contraceptives that have side effect in body weight and lipid metabolism. The objective of this study was to determine the differences of lipid profile between acceptors Depo Medroxyprogesterone Acetate and Levonorgestrel Implants. …”
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603
A machine learning model accurately identifies glycogen storage disease Ia patients based on plasma acylcarnitine profiles
Published 2025-01-01“…As GSD Ia patients demonstrate altered lipid metabolism and mitochondrial fatty acid oxidation, we built a machine learning model to identify GSD Ia patients based on plasma acylcarnitine profiles. …”
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604
Propionate metabolism in a human pathogenic fungus: proteomic and biochemical analyses
Published 2020-05-01“…During mycelium to yeast transition P. lutzii cells up-regulate transcripts related to lipid metabolism and cell wall remodeling in order to cope with the host body temperature. …”
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605
The relationship between non-HDL-C/HDL-C ratio and bone mineral density: an NHANES study
Published 2025-01-01“…These findings offer a new perspective on the relationship between lipid metabolism and bone metabolism and provide scientific evidence for the development of personalized osteoporosis prevention and treatment strategies.…”
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606
Exploring and Verifying the Mechanism and Targets of Shenqi Pill in the Treatment of Nonalcoholic Steatohepatitis via Network Pharmacology and Experiments
Published 2022-01-01“…Hepatic injury and lipid metabolism indicators of NASH rats were significantly improved after SQP treatment. …”
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607
Effects of dietary bile acid on the growth performance, intestinal health, blood biochemistry, and antioxidative response of Nile tilapia (Oreochromus niloticus) fed high-fat diets
Published 2025-03-01“…Thereby, bile acid (BA) is proposed to relieve the lipid metabolism dysfunction, oxidative stress, and malnutrition caused by HF. …”
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608
Short-term effects of follicle-stimulating hormone on immune function, lipid, and vitamin metabolism in transiently castrated men
Published 2025-01-01“…Results: FSH significantly upregulates key proteins involved in the modulation of inflammatory response and innate immune system (P ≤ 0.03) and dysregulates lipid metabolism, evidenced by downregulation of multiple apolipoproteins (P ≤ 0.04) and increased levels of cholesterol and glycerophospholipids (P ≤ 0.03). …”
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609
HDL proteome and apolipoproteins concentrations in severe ICU COVID-19 patients
Published 2025-01-01“…Abstract Background SARS-CoV-2 infection affects both lipid metabolism and lung function. The severity of the disease has been associated with reduced levels of both high-density lipoprotein (HDL) and low-density lipoprotein cholesterol. …”
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610
Associations between lipid-lowering drugs and urate and gout outcomes: a Mendelian randomization study
Published 2025-01-01“…ObjectiveGout is a common inflammatory arthritis and lipid metabolism plays a crucial role in urate and gout. …”
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611
Comprehensive Management of Polycystic Ovary Syndrome: The Role of Metformin in Addressing Metabolic and Endocrine Dysregulation
Published 2025-01-01“…Conclusion: The findings highlight metformin's three primary mechanisms of action: enhancing insulin sensitivity, inhibiting hepatic gluconeogenesis, and influencing lipid metabolism. Metformin is effective in improving metabolic parameters and restoring ovulatory function in women with PCOS. …”
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612
Studying sex differences in responses to fibroblast growth factor 21 administration in obese mice consuming a sweet-fat diet
Published 2023-07-01“…The aim of this study was to compare the effects of FGF21 on body weight, food preferences and glucose and lipid metabolism in C57Bl/6J male and female mice with SFD-induced obesity. …”
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613
Protective Effect of Sex Hormone-Binding Globulin against Metabolic Syndrome: In Vitro Evidence Showing Anti-Inflammatory and Lipolytic Effects on Adipocytes and Macrophages
Published 2018-01-01“…In this study, using adipocytes and macrophages, we focused on the in vitro effects of SHBG on inflammation as well as lipid metabolism. Incubation with 20 nM SHBG markedly suppressed lipopolysaccharide- (LPS-) induced inflammatory cytokines, such as MCP-1, TNFα, and IL-6 in adipocytes and macrophages, along with phosphorylations of JNK and ERK. …”
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614
Single-cell transcriptome atlas of lamprey exploring Natterin- induced white adipose tissue browning
Published 2025-01-01“…Moreover, we developed a transgenic mouse model expressing Natterin to elucidate the role of NATTERIN in lipid metabolism, whereas the browning of white adipose tissue was induced. …”
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615
The Validation of a Novel, Sex-Specific LDL-Cholesterol Equation and the Friedewald, Sampson-NIH, and Extended-Martin–Hopkins Equations Against Direct Measurement in Korean Adults...
Published 2025-01-01“…<b>Background/Objectives</b>: The currently established equations for calculating low-density lipoprotein cholesterol (LDLc) do not reflect the sex-specific differences in lipid metabolism. We aimed to develop a sex-specific LDLc equation (SSLE) and validate it with three established equations (Friedewald, Sampson-NIH, and ext-Martin–Hopkins) against direct LDLc measurement in Korean adults. …”
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616
Exosomal miR-122 derived from M2 macrophages induces osteogenic differentiation of bone marrow mesenchymal stem cells in the treatment of alcoholic osteonecrosis of the femoral hea...
Published 2025-01-01“…Abstract Alcoholic osteonecrosis of the femoral head (AIONFH) is caused by long-term heavy drinking, which leads to abnormal alcohol and lipid metabolism, resulting in femoral head tissue damage, and then pathological necrosis of femoral head tissue. …”
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617
Dose-dependent effects of hydroquinone on liver injury and lipid dysregulation based on SCD1/AMPK signaling pathway in C57BL/6 mice
Published 2025-01-01“…This study aimed to investigate the impact of different doses of HQ on liver injury and lipid metabolism in C57BL/6 mice, with a specific focus on the SCD1/AMPK signaling pathway. …”
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618
Ozone exposure and cardiovascular disease: A narrative review of epidemiology evidence and underlying mechanisms
Published 2025-01-01“…Proposed biological mechanisms suggest that O3 exposure engenders respiratory and systemic inflammation, oxidative stress, disruption of autonomic nervous and neuroendocrine systems, as well as impairment of coagulation function, glucose, and lipid metabolism. Ultimately, these processes contribute to vascular dysfunction and the development of CVD. …”
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619
The structural characteristics of dietary fibers from Tremella fuciformis and their hypolipidemic effects in mice
Published 2023-03-01“…The administration of tremella fibers improved the lipid metabolism disorderly situation of hyperlipidemia mice. …”
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620
Phthalates toxicity in vivo to rats, mice, birds, and fish: A thematic scoping review
Published 2025-01-01“…Studies focused on oxidative stress (34.64 %), apoptosis (22.22 %), steroid hormone deprivation (20.26 %), lipid metabolism disorder (11.76 %), and immunotoxicity (5.88 %) as mechanisms of toxicity. …”
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