Evaluation of the effects of short-term PM2.5 exposure on triglyceride-glucose metrics in a population in eastern China by Zhenpeng Guo, Chenchen Yang, Qiang Zhang, Xinling Shi, Xiaona Li, Qun Zhang, Jianming Wang

“…Controlling air pollution might contribute to maintainin normal lipid metabolism function.…”
Get full text

Golgi scaffold protein PAQR11 in pan-cancer landscape: A comprehensive bioinformatics exploration of expression patterns, prognostic significance, and potential immunological funct... by Zhu Liu, Zhi-Qiang Ling

“…PAQR11 influences lipid metabolism and susceptibility to ferroptosis in cancer cells. …”
Get full text

Functional Genetic Variant in ATG5 Gene Promoter in Acute Myocardial Infarction by Yexin Zhang, Xiaohui He, Jiarui Li, Wentao Yang, Yinghua Cui, Shuchao Pang, Haihua Wang, Bo Yan

“…Dysfunctional autophagy has been associated with abnormal lipid metabolism and inflammation. In previous studies, we have reported altered autophagic activity in AMI patients. …”
Get full text

Assessing clenbuterol’s modulation of metabolic and inflammatory pathways in Nile tilapia (Oreochromas niloticous) fed high fat diet by Aya G. Rashwan, Doaa H. Assar, Abdallah S. Salah, Muyassar H. Abualreesh, Shimaa M. R. Salem, Norah Althobaiti, Zizy I. Elbialy

“…Abstract This study was performed to reveal the metabolic effects and molecular mechanisms that govern the dietary incorporation of clenbuterol on growth performance, haemato-biochemical changes, histological alteration, and gene expression regulating glucose and lipid metabolism in normal and high-fat diets fed in Nile tilapia (Oreochromis niloticus). …”
Get full text

Association of Copper Status with Lipid Profile and Functional Status in Patients with Amyotrophic Lateral Sclerosis by Acsa Nara A. B. Barros, Mário Emílio T. Dourado, Lucia de Fatima C. Pedrosa, Lucia Leite-Lais

“…Copper can affect cellular oxidation and lipid metabolism. The aim of this study was to evaluate the association of copper status with lipid profile and functional status in patients with ALS. …”
Get full text

Substituting Fish Meal with Tubiechong (Eupolyphaga sinensis) By-Product in the Diets of Largemouth Bass (Micropterus salmoides): Effects on Growth, Meat Quality, and Liver Health by Yuhua Yue, Binbin Tong, Mingshi Chen, Xiaoxue Bao, Yanming Qiu, Ying Yang, Hui Yu, Yingying Yu

“…In the study, the replacement groups had lower T-CHO and HDL-C in serum (P<0.05), indicating that the Tubiechong by-product had an active role in improving blood lipid and regulating lipid metabolism. Simultaneously, the replacement groups had a normal structure with central hepatocytes’ nuclei and deviated from the center partly, while most of the hepatocytes were swollen in the control group with nuclear degeneration. …”
Get full text

Prophylactic and therapeutic effects of EsV3 on atherosclerotic lesions in ApoE−/− mice by Yaze Wang, Hifumi Ohishi, Rongji Wu, Hui Liu, Rong Xu

“…Moreover, serum oxidative stress markers (MDA, GSH, SOD) were measured to evaluate oxidative damage and lipid metabolism. Results Both atorvastatin and P-EsV3 treatments significantly lowered TC, TG, and LDL-C levels, with P-EsV3-H enhancing HDL-C levels (P < 0.05). …”
Get full text

Single-cell transcriptomes of dissecting the intra-tumoral heterogeneity of breast cancer microenvironment by Peixian Chen, Kaifeng Liang, Xiaofan Mao, Qiuyuan Wu, Zhiyan Chen, Yabin Jin, Kairong Lin, Tiancheng He, Shuqing Yang, Huiqi Huang, Guolin Ye, Juntao Gao, Dan Zhou, Zhihao Zeng

“…In macrophages, two mainly tumor associated macrophages (TAMs), TAM1 and TAM2, were also detected and the highly variable genes in TAM2 were strongly enriched in IFN-α and IFN-γ. The changes of lipid metabolism pathways in macrophages are closely related to the microenvironment of breast cancer. …”
Get full text

Exploring <i>RNF213</i> in Ischemic Stroke and Moyamoya Disease: From Cellular Models to Clinical Insights by Benjamin Y. Q. Tan, Charlene H. P. Kok, Megan B. J. Ng, Shaun Loong, Eric Jou, Leonard L. L. Yeo, Weiping Han, Christopher D. Anderson, Chiea Chuen Khor, Poh San Lai

“…This gene encodes an E3 ubiquitin ligase with diverse roles in angiogenesis, vascular remodeling, lipid metabolism, and cerebral blood flow regulation, yet its exact mechanisms in cerebrovascular pathology remain incompletely understood. …”
Get full text

Post-translational histone modifications associated with the development of metabolic dysfunction-associated fatty liver disease. Part 2. Histone methylation by O.E. Abaturov, A.O. Nikulina

“…Histone methy­lation and demethylation, mediating the expression of key genes involved in carbohydrate and lipid metabolism, determine both the occurrence and development of steatosis, inflammation and fibrosis of the liver in patients with metabolic dysfunction-­associated fatty liver disease. …”
Get full text

Natural History of Metabolic Dysfunction-Associated Steatotic Liver Disease: From Metabolic Syndrome to Hepatocellular Carcinoma by Melchor Alpízar Salazar, Samantha Estefanía Olguín Reyes, Andrea Medina Estévez, Julieta Alejandra Saturno Lobos, Jesús Manuel De Aldecoa Castillo, Juan Carlos Carrera Aguas, Samary Alaniz Monreal, José Antonio Navarro Rodríguez, Dulce María Fernanda Alpízar Sánchez

“…<i>Introduction</i>: Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) stems from disrupted lipid metabolism in the liver, often linked to obesity, type 2 diabetes, and dyslipidemia. …”
Get full text

Differentiation Potential of Pancreatic Fibroblastoid Cells/Stellate Cells: Effects of Peroxisome Proliferator-Activated Receptor Gamma Ligands by M.-L. Kruse, S. Hopf-Jensen, C. Timke, B. Agricola, G. Sparmann, A. Schmid, B. Sipos, A. Arlt, H. Schäfer

“…Cells treated with ciglitazone for three days showed enhanced lipid content and induction of proteins involved in lipid metabolism. Collagen synthesis was reduced in hPFC. …”
Get full text

Real-World HbA1c Changes Among Type 2 Diabetes Mellitus Patients Initiating Treatment With a 1.0 Mg Weekly Dose of Semaglutide for Diabetes by Noelle N. Gronroos, Caroline Swift, Monica S. Frazer, Andrew Sargent, Michael Leszko, Erin Buysman, Sara Alvarez, Tyler J. Dunn, Josh Noone

“…The majority of patients had lipid metabolism disorder (90.8%), hypertension (86.6%), diabetes with complications (86.8%), or other nutritional/endocrine/metabolic disorders (72.5%). …”
Get full text

Proteome‐Wide Mendelian Randomization Identifies Therapeutic Targets for Abdominal Aortic Aneurysm by Ka Zhang, Yuan Liu, Aiqin Mao, Changzhu Li, Li Geng, Hao Kan

“…Several causal proteins are involved in pathways regulating lipid metabolism, immune responses, and extracellular matrix organization. …”
Get full text

The triterpenoids-enriched extracts from Antrodia cinnamomea mycelia attenuate alcohol-induced chronic liver injury via suppression lipid accumulation in C57BL/6 mice by Yange Liu, Ronglong Chen, Lanzhou Li, Ruitao Dong, Hui Yin, Yawen Wang, Anhui Yang, Jianbin Wang, Changtian Li, Di Wang

“…According to further data, ACT prevented alcoholic liver injury may be associated with mediating lipid metabolism-related to PGC-1α and NF-κB signaling. …”
Get full text

Low Citrate Synthase Activity Is Associated with Glucose Intolerance and Lipotoxicity by Yosra Alhindi, Lobke M. Vaanholt, Mustafah Al-Tarrah, Stuart R. Gray, John R. Speakman, Catherine Hambly, Bader S. Alanazi, Brendan M. Gabriel, Arimantas Lionikas, Aivaras Ratkevicius

“…This could be due to impaired lipid metabolism in muscle cells.…”
Get full text

The Optimum Lipid Level for the Juvenile Redclaw Crayfish Cherax quadricarinatus: Practical Diets with Soybean Oil as the Lipid Source by Chengzhuang Chen, Chang Xu, Xiaolong Yang, Yongyi Jia, Zhimin Gu, Erchao Li

“…In this study, the optimum dietary lipid level was explained by analyzing the growth performance, antioxidant state, lipid metabolism, and gut microbiota of C. quadricarinatus after an eight-week cultivation trial. …”
Get full text

Prevalence and Risk Factors of Childhood Hypertension in Urban-Rural Areas of China: A Cross-Sectional Study by Xiaohua Liang, Lun Xiao, Yetao Luo, Jiapei Xu

“…Children living in rural areas combined with obesity, low social economic status, dietary imbalance, and abnormal lipid metabolism were associated with an increased risk of hypertension, and routine care programs should be conducted to prevent childhood hypertension.…”
Get full text

Plasma proteome fingerprint in kidney diseases by Kirill S. Nikolsky, Arthur T. Kopylov, Valeriya I. Nakhod, Natalia V. Potoldykova, Dmitry V. Enikeev, Tatiana V. Butkova, Liudmila I. Kulikova, Kristina A. Malsagova, Vladimir R. Rudnev, Denis V. Petrovskiy, Alexander A. Izotov, Anna L. Kaysheva

“…These proteins are important participants of complement and coagulation cascade activation and lipid metabolism.ResultsThe revealed phosphorylated proteoforms (CFB, C4A/C4B, F2, APOB, TTR, and NRAP) were identified. …”
Get full text

Novel immune cross-talk between inflammatory bowel disease and IgA nephropathy by Qianqian Yan, Zihao Zhao, Dongwei Liu, Jia Li, Shaokang Pan, Jiayu Duan, Zhangsuo Liu

“…Kyoto Encyclopedia of Genes and Genomes analysis showed 15 mutual pathways between the two diseases, with lipid metabolism playing a vital role in the cross-talk. …”
Get full text