Integrated transcriptome and metabolome analysis of liver reveals unsynchronized growth mechanisms in blunt-snout bream (Megalobrama amblycephala) by Qi Liu, Xue Zou, Ming Zhao, Qianqian Guan, Zhaoyang Xuan, Lusha Liu, Zexia Gao

“…KEGG and GO enrichment analysis indicated that the DEGs with higher expression level were significantly correlated with insulin signaling pathway, steroid hormone and lipid metabolism related pathway (PPAR signaling pathway and fatty acid degradation). …”
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An untargeted metabolomic analysis of acute AFB1 treatment in liver, breast, and lung cells. by Heidi H Cao, Sabrina Molina, Susan Sumner, Blake R Rushing

“…HepG2 cell pathway analyses revealed significant pathway perturbations in lipid metabolism, carnitine synthesis, catecholamine biosynthesis, purine metabolism, and spermidine and spermine biosynthesis. …”
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Determination of Irisin, Body Mass Index, and Other Biochemical Parameters in a Sample of Iraqi Type II Diabetic Patients by Takwa Al Koloob Ali Chachan, Huda Farhan, Shatha Hamed

“… Evidence suggests that Irisin, a peptide hormone, may play a role in lipid metabolism, insulin resistance, and obesity. On the other hand, its role in type 2 diabetic Mellitus [T2DM] in humans is uncertain. …”
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Investigation of the Protective Effects of Phlorizin on Diabetic Cardiomyopathy in db/db Mice by Quantitative Proteomics by Qian Cai, Baoying Li, Fei Yu, Weida Lu, Zhen Zhang, Mei Yin, Haiqing Gao

“…Using isobaric tag for relative and absolute quantitation (iTRAQ) proteomics, we identified differentially expressed proteins involved in cardiac lipid metabolism, mitochondrial function, and cardiomyopathy, suggesting that phlorizin may prevent the development of diabetic cardiomyopathy by regulating the expression of key proteins in these processes. …”
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Global epidemiology of Mycobacterium tuberculosis lineage 4 insights from Ecuadorian genomic data by Gabriel Morey-León, Paulina M. Mejía-Ponce, Juan Carlos Fernández-Cadena, Evelyn García-Moreira, Derly Andrade-Molina, Cuauhtémoc Licona-Cassani, Pablo Fresia, Luisa Berná

“…Our results revealed significant genomic diversity among the isolates, particularly in the genes related to protein processing, carbohydrate metabolism, lipid metabolism, and xenobiotic biodegradation and metabolism. …”
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Transcriptomics reveals substance biosynthesis and transport on membranes of Listeria monocytogenes affected by antimicrobial lipopeptide brevilaterin B by Yangliu Liu, Yawei Ning, Zhou Chen, Panpan Han, Tongxin Zhi, Siting Li, Aijin Ma, Yingmin Jia

“…Gene Ontology and Kyoto Encyclopedia of Genes and Genomes analysis indicated that brevilaterin B influenced multiple pathways of L. monocytogenes, including peptidoglycan biosynthesis, membrane transport (ATP-binding cassette transports, ion transport), cellular metabolism (amino acid and lipid metabolism), ATP synthesis, and activation of the stress response (quorum sensing and bacterial chemotaxis). …”
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Hsp90α promotes lipogenesis by stabilizing FASN and promoting FASN transcription via LXRα in hepatocellular carcinoma by Zihao Deng, Lixia Liu, Guantai Xie, Zhenming Zheng, Jieyou Li, Wenchong Tan, Yaotang Deng, Jinxin Zhang, Manfeng Liang, Yingxia Wu, Zhifeng Zhou, Yan Li, Yukui Chen, Yaling Huang, Hairou Su, Guibing Wu, Xiongjie Shi, Shengpei Cen, Yandan Liao, Yilin Liu, Fei Zou, Xuemei Chen

“…Studies have revealed that Hsp90 regulates the lipid metabolism of HCC, but the effect of Hsp90 on FASN still remains unknown. …”
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Influence of Omega-3 and Green Tea Extract on Alcohol-Induced Liver Injury in Rats by Ridha Hassan Hussein, Zana Hassan Ibrahim

“…Ethanol consumption impaired hepatic functions, disturbed lipid metabolism, induced hyperlipidemia and increased oxidative stress. …”
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Potential involvement of peroxisome proliferator-activated receptors in the inhibition of mammary lipid synthesis during diet-induced milk fat depression by A. Haile, D.E. Oliveira, Y.R. Boisclair, D.E. Bauman, K.J. Harvatine

“…We hypothesized that the expression of PPAR, which regulate lipid metabolism and bind to PUFA, could be modulated by biohydrogenation intermediates that induce MFD, thereby interfering with milk fat synthesis. …”
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Exercise as a mean to reverse the detrimental effect of high-fat diet on bone’s fracture characteristics by Ilias Doulamis, Despina N. Perrea, Panagiotis E. Chatzistergos, Athanasios S. Mitousoudis, Stavros K. Kourkoulis

“…The aim of this study is to investigate whether exercise can reverse some of the adverse effects of high-fat-diet-induced obesity on lipid metabolism and bone biomechanical properties. A total of 26 adult male C57bl/6J mice were randomly assigned into three groups: (A) Control group (n=6), (B) High-fat diet group (n=10), (C) High-fat diet and exercise group (n=10). …”
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Treatment with Lobeglitazone Attenuates Hepatic Steatosis in Diet-Induced Obese Mice by Sorim Choung, Kyong Hye Joung, Bo Ram You, Sang Ki Park, Hyun Jin Kim, Bon Jeong Ku

“…To evaluate a possible effective drug for treatment of NAFLD, we investigated the effects of a newly developed TZD, lobeglitazone, with an emphasis on hepatic lipid metabolism. Lobeglitazone treatment for 4 weeks in high fat diet- (HFD-) induced obese mice (HL group) improved insulin resistance and glucose intolerance compared to HFD-induced obese mice (HU group). …”
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Comparative Transcriptional Profiling of Two Contrasting Barley Genotypes under Salinity Stress during the Seedling Stage by Runhong Gao, Ke Duan, Guimei Guo, Zhizhao Du, Zhiwei Chen, Liang Li, Ting He, Ruiju Lu, Jianhua Huang

“…Moreover, key enzymes in the pathways of jasmonic acid biosynthesis, lipid metabolism and indole-3-acetic acid homeostasis were specifically affected by salt stress in salt tolerance genotype. …”
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Effect of Ileal Transposition (IT) on Angiopoietin-Like Protein-8 (ANGPTL8) and Pentraxin (PTX3) Plasma Level in Sprague-Dawley Rats Fed High-Fat Diet (HFD) by Tomasz Sawczyn, Dominika Stygar, Katarzyna Nabrdalik, Michał Kukla, Oliwia Masri, Łukasz Magrowski, Wojciech Karcz, Jerzy Jochem

“…Based on recent findings, the present study focuses on the relationship between the effects of ileal transposition (IT), high-fat diet (HFD), and selected markers of lipid metabolism and inflammation. Methods. Forty-eight male rats were divided into two groups: HFD and control diet (CD) fed rats. …”
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The Role of Phosphatidylethanolamine-N-methyltransferase (PEMT) Gene rs12449964 Polymorphism in the Development of Acute Pancreatitis and its Complications by T. A. Samgina, Yu. E. Azarova, Yu. V. Kanishchev, V. A. Lazarenko, P. M. Nazarenko, A. V. Polonikov

“…The phosphatidylethanolamine-N-methyltransferase enzyme plays a significant role in the regulation of lipid metabolism by catalyzing the process of methylation of phosphatidylethanolamine to phosphatidylcholine. …”
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Exploring serum miR-33b as a novel diagnostic marker for hypercholesterolemia and obesity: insights from a pilot case-control study by Yaser Masoumi-Ardakani, Mostafa Eghbalian, Hossein Fallah, Alireza Jafari, Beydolah Shahouzehi

“…Abstract Obesity and atherosclerosis are significant metabolic diseases characterized by disrupted lipid metabolism. MicroRNAs (miRNAs) are small, conserved, non-coding RNA sequences consisting of approximately 22 nucleotides, playing crucial roles in biological and pathological functions. …”
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Gestational hypercholanemia suppresses pregnancy‐associated adipose mass increase and stimulates a pro‐inflammatory environment in mice by Vanya Nikolova, Alice L. Mitchell, Elena Bellafante, Eugene Jansen, Georgia Papacleovoulou, Per‐Olof Bergh, Hanns‐Ulrich Marshall, Catherine Williamson

“…Pregnancy and CA diet reduced lipid metabolism transcript expression in adipocytes. CA supplementation during pregnancy increased plasma ROM by 1.24‐fold and suppressed inflammatory‐modulating pentraxin‐2/3 and insulin‐like growth factor 1 (IGF‐1) levels by >50% and >80%, respectively. …”
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Mitochondrial chaperonin DNAJC15 promotes vulnerability to ferroptosis of chemoresistant ovarian cancer cells by Stefano Miglietta, Manuela Sollazzo, Iacopo Gherardi, Sara Milioni, Beatrice Cavina, Lorena Marchio, Monica De Luise, Camelia Alexandra Coada, Marco Fiorillo, Anna Myriam Perrone, Ivana Kurelac, Giuseppe Gasparre, Luisa Iommarini, Anna Maria Ghelli, Anna Maria Porcelli

“…DNAJC15 is a mitochondrial TIMM23-related co-chaperonin known for its role in regulating oxidative phosphorylation efficiency, oxidative stress response and lipid metabolism. Recently, it has been proposed that the loss of DNAJC15 correlates with cisplatin (CDDP)-resistance onset in ovarian cancer (OC), suggesting this protein as a potential prognostic factor during OC progression. …”
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Severe Diabetic Ketoacidosis in Children with Type 1 Diabetes: Ongoing Challenges in Care by Simone Foti Randazzese, Mariarosaria La Rocca, Bruno Bombaci, Alessandra Di Pisa, Elèna Giliberto, Teresa Inturri, Daniel Militi, Fortunato Lombardo, Eloisa Gitto, Giuseppina Salzano, Stefano Passanisi

“…Pathogenesis is linked to insulin deficiency and an excess of counter-regulatory hormones, which disrupt glucose, protein, and lipid metabolism, causing hyperglycemia, ketosis, acidosis, dehydration, and electrolyte imbalances. …”
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New perspectives on DNA methylation modifications in ocular diseases by Fei-Fei Zong, Da-Dong Jia, Guang-Kun Huang, Meng Pan, Hao Hu, Shi-Yi Song, Liang Xiao, Ru-Weng Wang, Liang Liang

“…In addition, inflammation, oxidative stress and lipid metabolism, which abnormal DNA methylation is closely related to, are also considered to be major factors in eye diseases. …”
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MicroRNA-223 Expression Is Upregulated in Insulin Resistant Human Adipose Tissue by Tung-Yueh Chuang, Hsiao-Li Wu, Chen-Chun Chen, Gloria Mabel Gamboa, Lawrence C. Layman, Michael P. Diamond, Ricardo Azziz, Yen-Hao Chen

“…MicroRNAs (miRNAs) are short noncoding RNAs involved in posttranscriptional regulation of gene expression and influence many cellular functions including glucose and lipid metabolism. We previously reported that adipose tissue (AT) from women with polycystic ovary syndrome (PCOS) or controls with insulin resistance (IR) revealed a differentially expressed microRNA (miRNA) profile, including upregulated miR-93 in PCOS patients and in non-PCOS women with IR. …”
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