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341
Mitochondrial DNA in atherosclerosis research progress: a mini review
Published 2025-02-01“…Damage and release of mtDNA are considered central drivers in the development of AS, as they participate in the progression of AS by activating inflammatory pathways and affecting lipid metabolism. Therefore, therapeutic strategies targeting mtDNA and its downstream effects may provide new avenues to address this global health challenge.…”
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342
The Role of PPARγ in Helicobacter pylori Infection and Gastric Carcinogenesis
Published 2012-01-01“…Peroxisome proliferator-activated receptor γ (PPARγ) is a nuclear receptor that is important in many physiological and pathological processes, such as lipid metabolism, insulin sensitivity, inflammation, cell proliferation, and carcinogenesis. …”
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343
Curcumin as a Supportive Therapy in Type 2 Diabetic Patients
Published 2024-01-01“…The management of diabetes is a lifelong process that requires diabetic education, attempts to achieve near optimal glycemic control, minimizing cardiovascular and other long-term risk factors, and avoidance of drugs that can exacerbate abnormalities of insulin and lipid metabolism. In the treatment of T2DM, curcumin has demonstrated much potential as an adjunct therapy due to its anti-inflammatory properties and its ability to reduce oxidative stresses within the body. …”
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344
The high-density lipoprotein binding protein HDLBP is an unusual RNA-binding protein with multiple roles in cancer and disease
Published 2024-12-01“…In this review, we give an overview of some of the functions of the protein as well as introduce its impact on different kinds of cancer, its connection to lipid metabolism and its role in viral infection. We also aim at addressing the possible use of HDLBP as a drug target or biomarker and discuss its future implications.…”
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345
Dietary protein requirement of Chinese hook snout carp (Opsariichthys bidens) and transcriptomic analysis of the liver in response to different protein diets
Published 2025-03-01“…In contrast, the P35 group presented lower amino acid and lipid metabolism (e.g., stearoyl-CoA desaturase, glutamine synthetase, and bile salt-activated lipase) expression levels. …”
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346
The efficacy and safety of qiwei baizhu san in the treatment of type 2 diabetes mellitus: a systematic review and meta-analysis
Published 2025-01-01“…The impact of QWBZS therapy alone on HOMA-IR and lipid metabolism remained unclear due to the limited number of trials included. …”
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347
Association between cardiometabolic index and risk of testosterone deficiency in adult men: a cross-sectional study
Published 2025-01-01“…Only adult males who completed physical measurements, lipid metabolism assessments, and testosterone measurements were included in the final analysis. …”
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348
Peroxisome Proliferator-Activated Receptor and Retinoic X Receptor in Alcoholic Liver Disease
Published 2009-01-01“…The increased ethanol metabolism, in turn, leads to alteration of the redox balance of the cells and impairment of RXR/PPAR functions by direct and indirect effects of acetaldehyde, resulting in deranged lipid metabolism, oxidative stress, and release of proinflammatory cytokines. …”
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349
Adropin: a key player in immune cell homeostasis and regulation of inflammation in several diseases
Published 2025-01-01“…Adropin plays a critical role in glucose and lipid metabolism, as well as insulin resistance, by modulating multiple signaling pathways that contribute to the reduction of obesity and the improvement of blood lipid and glucose homeostasis. …”
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350
Selective Modulators of PPAR-γ Activity: Molecular Aspects Related to Obesity and Side-Effects
Published 2007-01-01“…Peroxisome proliferator-activated receptor γ (PPAR-γ) is a key regulator of lipid metabolism and energy balance implicated in the development of insulin resistance and obesity. …”
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351
Possible Immunosuppressive Effects of Drug Exposure and Environmental and Nutritional Effects on Infection and Vaccination
Published 2015-01-01“…The drugs of importance include antipyretics, anticoagulants, tranquilizers, and substances influencing lipid metabolism but also commonly used drugs of abuse like alcohol or cannabinoids. …”
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352
Biological rhythms of the liver
Published 2024-03-01“…Disorders in the expression of these factors have a significant impact on the functioning of the liver. In such cases lipid metabolism, cholesterol metabolism, bile acid metabolism, alcohol metabolism, and xenobiotic detoxification can be significantly affected. …”
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353
Drosophila melanogaster as an alternative animal model in fat metabolism studies
Published 2024-07-01“…It is discovered that Drosophila accommodates a range of cell types and organs which entail lipid metabolism and related energy homeostasis similar to those of mammals. …”
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354
Clinical Trials of Probiotic Strains in Selected Disease Entities
Published 2020-01-01“…A number of studies prove that probiotics strengthen cognitive functions, reduce anxiety, and regulate the lipid metabolism in the human body. Probiotics used in humans are most often of the Lactobacillus and Bifidobacterium species. …”
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355
Seaweed nutraceuticals and their therapeutic role in disease prevention
Published 2019-09-01“…Keywords: Functional ingredients, Glucose metabolism, Lipid metabolism, Macroalgae, Bioavailability…”
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356
Exploring Disparities in Gill Physiological Responses to NaHCO<sub>3</sub>-Induced Habitat Stress in Triploid and Diploid Crucian Carp (<i>Carassius auratus</i>): A Comprehensive I...
Published 2024-12-01“…Metabolomic investigations suggest alterations in purine metabolism, lipid metabolism, sphingolipid metabolism, and aminoglycan and nucleotide sugar metabolism following NaHCO<sub>3</sub> exposure. …”
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357
Time-restricted feeding improves metabolic syndrome by activating thermogenesis in brown adipose tissue and reducing inflammatory markers
Published 2025-01-01“…The study provides mechanistic insights into the beneficial effects of TRF, highlighting its potential in modulating lipid metabolism and exerting anti-inflammatory effects.…”
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358
Impact of leachate from boiled-water-treated plastic products on male reproductive health: Insights from transcriptomic and metabolomic profiling
Published 2025-01-01“…Transcriptome analysis showed significant changes in genes associated with spermatogenesis following exposure to leachates, while metabolome analysis indicated an impact on the lipid metabolism pathway. Overall, the study provides evidence that oral exposure to leachates from boiled-water-treated plastic cups could negatively affect spermatogenesis and lipid metabolism, thereby posing risks to male reproductive health. …”
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359
Exploring the alleviating effects of Bifidobacterium metabolite lactic acid on non-alcoholic steatohepatitis through the gut-liver axis
Published 2025-01-01“…The evaluation of liver function and lipid metabolism was conducted using the liver-to-body weight ratio, histological staining, and biochemical assays. …”
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360
Bacillus subtilis HGCC-1 improves growth performance and liver health via regulating gut microbiota in golden pompano
Published 2025-01-01“…Therefore, the aim of this study was to investigate the effect of Bacillus subtilis HGCC-1, an indigenous probiotic isolated from fish, on growth performance, host lipid metabolism, liver inflammation and gut microbiota of golden pompano. 160,000 golden pompanos with the initial body weight of 93.6 ± 5.0 g was randomly assigned to two dietary groups: Control and HGCC-1 (control diet supplemented with 0.3 g/kg Bacillus subtilis HGCC-1 fermentation product), and after three weeks of feeding, 26 golden pompanos were randomly collected from each group for gut microbiome and host phenotype analysis. …”
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