The Effect of Aerobic Exercise on the Oxidative Capacity of Skeletal Muscle Mitochondria in Mice with Impaired Glucose Tolerance by Dan Wang, Dong-Mou Jiang, Rong-Rong Yu, Lin-Lin Zhang, Yan-Zhong Liu, Jia-Xin Chen, Hai-Chun Chen, Yi-Ping Liu

“…Results. (1) Mice with high-fat diet for 30 weeks showed impaired glucose tolerance, insulin resistance, and lipid metabolism disorders. The level of LDH, PDH, SDH, and CCO in the gastrocnemius homogenate of mice was reduced. …”
Get full text

Effect of Melatonin as an Antioxidant Drug to Reverse Hepatic Steatosis: Experimental Model by Blanca Martínez Soriano, Antonio Güemes, Guillermo Pola, Azucena Gonzalo, Pilar Palacios Gasós, Ana C. Navarro, Roberto Martínez-Beamonte, Jesús Osada, José J. García

“…However, we have found several signs of improvement at the histological level, at the level of lipid metabolism, and at the level of oxidative stress parameters. …”
Get full text

HDL Particle Size and Functionality Comparison between Patients with and without Confirmed Acute Myocardial Infarction by Raissa de Miranda Teixeira, Nicole Cruz de Sá, Ana Paula Caires dos Santos, Vanessa Rocha Anjos e Silva, Elaine Christine de Magalhães Cabral Albuquerque, Luiz Claudio Lemos Correia, Ricardo David Couto

Get full text

PPAR-α regulates metabolic remodelling and participates in myocardial fibrosis in patients with atrial fibrillation of rheumatic heart disease by Xiaoying Hu, Daisong Jiang, Zheng Zhang, Zhenmei An

“…PPAR-α may participate in the pathogenesis of myocardial fibrosis in rheumatic heart disease AF by regulating glucose metabolism, lipid metabolism, and mitochondrial function.…”
Get full text

Potential Role of ANGPTL4 in the Cross Talk between Metabolism and Cancer through PPAR Signaling Pathway by Laura La Paglia, Angela Listì, Stefano Caruso, Valeria Amodeo, Francesco Passiglia, Viviana Bazan, Daniele Fanale

“…At first, ANGPTL4 has been identified as an adipokine exclusively involved in lipid metabolism, because of its prevalent expression in liver and adipose tissue. …”
Get full text

Piperine regulates the circadian rhythms of hepatic clock gene expressions and gut microbiota in high-fat diet-induced obese rats by Weiyun Zhang, Chi-Tang Ho, Wenlian Wei, Jie Xiao, Muwen Lu

“…In this study, the modulatory effects of piperine (PIP) on lipid metabolism homeostasis, gut microbiota community and circadian rhythm of hepatic clock gene expressions in obese rats were investigated. …”
Get full text

Daily feeding frequency impacts muscle characteristics and fat deposition in finishing pigs associated with alterations in microbiota composition and bile acid profile by Luga Hu, Huayu Tang, Zhaoxi Xie, Hongyu Yi, Lunjie Feng, Pan Zhou, Yong Zhang, Jingbo Liu, Xiang Ao, Jianchuan Zhou, Honglin Yan

“…It remains unknown whether adjusting feeding frequency could effectively regulate both skeletal muscle development and whole-body lipid metabolism and thus affect carcass composition and feed conversion efficiency. …”
Get full text

Curcumin Prevents Free Fatty Acid-Induced Lipid Accumulation via Targeting the miR-22-3p/ CRLS1 Pathway in HepG2 Cells by Yuanyuan Mei, Xiaoting Sun, Shi-Ying Huang, Xiaowen Wu, Kuo-Ting Ho, Liming Lu, Chaoxiang Chen, Jian Li, Jingwen Liu, Guiling Li

“…Dysregulated lipid metabolism in liver is an important hallmark of non-alcoholic fatty liver disease (NAFLD), which may be modulated by dietary polyphenols or microRNAs (miRNAs). …”
Get full text

The Different Insulin-Sensitising and Anti-Inflammatory Effects of Palmitoleic Acid and Oleic Acid in a Prediabetes Model by Denisa Miklankova, Irena Markova, Martina Hüttl, Barbora Stankova, Hana Malinska

“…OA had a beneficial effect on lipid metabolism and improved inflammation by modulating AA metabolism.…”
Get full text

Obesity-Related Asthma: Immune Regulation and Potential Targeted Therapies by Yuze Yuan, Nan Ran, Lingxin Xiong, Guoqiang Wang, Xuewa Guan, Ziyan Wang, Yingqiao Guo, Zhiqiang Pang, Keyong Fang, Junying Lu, Chao Zhang, Ruipeng Zheng, Jingtong Zheng, Jie Ma, Fang Wang

“…Herein, we describe the immune regulators of lipid metabolism in obesity as well as the interplay of obesity and asthma. …”
Get full text

Nile tilapia juveniles reared at cold suboptimal water temperatures do not benefit from dietary supplementation with cholesterol by Jorge Filipe Banze, Renata Oselame Nobrega, Bruna Mattioni, Bianca Leticia Richter, Katharinne Ingrid Moraes de Carvalho, Jacó Joaquim Mattos, Maria Risoleta Freire Marques, James Eugene Pettigrew, Débora Machado Fracalossi

“…This study aimed to assess the dietary cholesterol supplementation effect on growth, nutrient digestibility, and lipid metabolism of Nile tilapia under suboptimal water temperature (22 °C). …”
Get full text

Metformin and Probiotics Interplay in Amelioration of Ethanol-Induced Oxidative Stress and Inflammatory Response in an In Vitro and In Vivo Model of Hepatic Injury by Farhin Patel, Kirti Parwani, Dhara Patel, Palash Mandal

“…In vitro, probiotic V and Met in combination prevented ethanol-induced cellular injury, ER stress, oxidative stress, and regulated lipid metabolism as well as inflammatory response in HepG2 cells. …”
Get full text

PPARα suppresses growth of hepatocellular carcinoma in a high-fat diet context by reducing neutrophil extracellular trap release by Banglun Pan, Zhu Zhang, Dongjie Ye, Xiaoxia Zhang, Yuxin Yao, Yue Luo, Haijie Hong, Xinran Cai, Yanling Chen, Nanhong Tang

“…Furthermore, the disruption of PPARα-mediated lipid metabolism was responsible for the release of NETs. …”
Get full text

Steatotic liver disease diagnosed in a 24-year-old woman with Rett syndrome: a case report by Larissa Albino, Adil Adatia, Aducio Thiesen, Brendan Halloran, Victor Dong, Carlos Moctezuma-Velázquez

“…Rett syndrome (RTT) is a neurodevelopmental disorder caused by mutations in the MECP2 gene, potentially disrupting lipid metabolism and leading to dyslipidemia (DLD) and steatotic liver disease (SLD). …”
Get full text

Lacticaseibacillus paracasei K56 inhibits lipid accumulation in adipocytes by promoting lipolysis by Silu Wang, Jinxing Li, Wei-Hsien Liu, Niya Li, Huijing Liang, Weilian Hung, Qiuyue Jiang, Ruyue Cheng, Xi Shen, Fang He

“…The expression of lipid metabolism-related markers of adipocytes, and the content of cytokines in CMs were detected. …”
Get full text

Role of gut microbiota and fecal metabolites in the protective effect of soybean pulp-rich diet against estrogen-induced cholestasis in rats by Jiawei Wang, Qichao Hu, Jianying Wang, Liwei Lang, Shizhang Wei, Haotian Li, Manyi Jing, Xiao Ma, Yanling Zhao, Xuelin Zhou

“…Moreover, the soybean pulp-rich diet could modulate the abundances of Prevotella spp. and Tyzzerella, reducing EIC by regulating lipid metabolism and short-chain fatty acids synthesis. …”
Get full text

Peroxisome Proliferator-Activated Receptor Targets for the Treatment of Metabolic Diseases by Francisco A. Monsalve, Radha D. Pyarasani, Fernando Delgado-Lopez, Rodrigo Moore-Carrasco

“…PPAR-α and PPAR-γ are mainly involved in regulating lipid metabolism, insulin sensitivity, and glucose homeostasis, and their agonists are used in the treatment of hyperlipidemia and T2DM. …”
Get full text

Effects of Moringa oleifera Leaf Extract on Liver Histopathology: A Systematic Review by Titing Nurhayati, Muhamad Farrel Ridho, Putri Teesa Radhiyanti Santoso, Setiawan Setiawan, Hanna Goenawan, Vita Murniati Tarawan

“…From the research that had been done, Moringa oleifera leaf extract contributes to give significant improvement on liver histopathological features, glucose, and lipid metabolism on animal sample model.…”
Get full text

Virtual screening and molecular docking of Indonesian phytoconstituents as potential inhibitors of peroxisome proliferator-activated receptor gamma in polycystic ovary syndrome by Tunjungseto Arif, Iffatunnisa Fakhriyah, Pratiwi Intan Winta, Alif Azzam Muhyiddin Afrizal, Ahsan Fadhil, Santoso Budi

“…Data of 6776 phytoconstituents from the Indonesian Medicinal Plant Database were screened for compounds with Pa>0.3 as “Insulin Sensitivity”, “Lipid metabolism”, and “Anti-inflammation” using PASSOnline. …”
Get full text

Targeted lipidomics analysis of possible molecular mechanisms of lipid changes in temporal lobe epilepsy models by Huaiyu Sun, Xuewei Li, Zhiqing Chen, Hongmei Meng

“…The results and methods described provide a comprehensive analysis of lipid metabolism in temporal lobe epilepsy and a new therapeutic target for the treatment of epilepsy.…”
Get full text