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Impaired RelA signaling and lipid metabolism dysregulation in hepatocytes: driving forces in the progression of metabolic dysfunction-associated steatotic liver disease
Published 2025-02-01“…Impaired RelA signaling remodeled the ER stress response and lipid metabolism, and enhanced lipid accumulation and lipid toxicity. …”
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INHIBITION OF LIPID PEROXIDATION AND MICROBIOLOGICAL IMPROVEMENT OF BROILER THIGH QUALITY AND CHARACTERISTICS BY ADDING CYPERUS ROTUNDUS POWDER AND VITAMIN E TO CHICKEN FEED
Published 2024-12-01“…The treatments that prevented lipid oxidation the most were the 5 and 7.5 g/kg feeds. …”
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643
Low apolipoprotein A1 and high apolipoprotein B levels indicate specific lipid changes in treatment naïve early psoriatic arthritis
Published 2025-01-01“…Objectives To investigate serum lipid profile in early, treatment-naïve psoriatic arthritis (PsA) and to determine whether changes in classical lipids or apolipoproteins are specific to PsA.Methods Total cholesterol, non-high-density lipoprotein cholesterol (non-HDL-c), low-density lipoprotein cholesterol (LDL-c), HDL-c, triglycerides, apolipoprotein B (ApoB) and apolipoprotein A1 (ApoA1) were compared in newly diagnosed untreated PsA patients (n=75) to sex- and age-matched controls (healthy control (HC)) (n=61) and early untreated rheumatoid arthritis (RA) patients (n=50).Results Among classical lipid measurements, HDL-c levels were lower in PsA than in HC and RA (df 2, χ210, p=0.006, PsA vs HC p=0.013). …”
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Achieving prediabetes reversal in China: a nationwide longitudinal study on the role of blood glucose and lipid management in middle-aged and elderly adults
Published 2025-01-01“…Additionally, evaluated blood lipid profiles reduced the odds of regression to NGR.ConclusionThis study underscores the influence of age, gender, abdominal obesity, LDL-C levels, FPG, HbA1c, and blood lipid profiles on the likelihood of regressing from prediabetes to NGR. …”
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Lipid Deposition in Skeletal Muscle Tissues and Its Correlation with Intra-Abdominal Fat: A Pilot Investigation in Type 2 Diabetes Mellitus
Published 2025-01-01Subjects: Get full text
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650
Microfluidic Synthesis of miR-200c-3p Lipid Nanoparticles: Targeting ZEB2 to Alleviate Chondrocyte Damage in Osteoarthritis
Published 2025-01-01Subjects: Get full text
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651
Serum Lipid and Glycemic Profile in HARRT-Naïve and HARRT-Exposed HIV Patients in Enugu State, Nigeria: A Case–Control Study
Published 2024-07-01“…Background: Although highly active antiretroviral therapy (HAART) has improved immunologic and virologic outcomes, as well as the quality of life of human immunodeficiency virus (HIV)-positive patients, it has worsened a wide range of metabolic derangements associated with HIV/AIDS. A wide range of lipid abnormalities and dysglycemia have been reported in patients on HARRT. …”
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Total flavonoids of Abelmoschus manihot ameliorate lipid deposition in HK-2 cells by inhibiting fatty acid uptake mediated by CD36
Published 2024-12-01Subjects: Get full text
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Lipid Peroxidation-Mediated Inflammation Promotes Cell Apoptosis through Activation of NF-κB Pathway in Rheumatoid Arthritis Synovial Cells
Published 2015-01-01“…Our results indicated that products of lipid peroxidations, 4-HNE, may induce synovial intrinsic inflammations by activating NF-κB pathways and it may lead to cell apoptosis. …”
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SDZ MRL 953, A Novel Synthetic Lipid a Analogue, Induces Tolerance to the Lethal Effects of Endotoxin and Enhances Nonspecific Immunity
Published 1992-01-01“…An attractive alternative appears to be the induction of hyporesponsiveness to LPS by synthetic lipid A analogues. SDZ MRL 953, a novel prototype of lipid A analogues. was examined for its ability to induce early-phase tolerance against experimental endotoxemia in mice following single or multiple administrations 2, 24, or 72 h before challenge. …”
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Evaluation of the Obesity Prevention, Blood Glucose, and Blood Lipid Control of Vietnamese Rice Varieties in High-Fat Diet-Induced Obese Mice
Published 2021-01-01“…The golden flower glutinous rice (GN), with low amylose and fiber content, gave worse blood lipid parameters than that of GM and LĐ. Histopathological studies of white adipose and liver tissues showed that LĐ and GM significantly reduced the symptoms of obesity and fatty liver compared with the others, especially compared to GN. …”
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Deficiency of the mitochondrial transporter SLC25A47 minimally impacts hepatic lipid metabolism in fasted and diet-induced obese mice
Published 2025-02-01“…Objective: The peroxisome proliferator-activated receptor-alpha (PPARα) plays a central role in lipid metabolism in the liver by stimulating the expression of hundreds of genes. …”
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Multispecies pasture diet and cow breed affect the functional lipid profile of milk across lactation in a spring-calving dairy system
Published 2025-02-01Subjects: Get full text
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A Snake Venom-Secreted Phospholipase A2 Induces Foam Cell Formation Depending on the Activation of Factors Involved in Lipid Homeostasis
Published 2018-01-01“…MT-III, a snake venom GIIA sPLA2, which shares structural and functional features with mammalian GIIA sPLA2s, activates macrophage defense functions including lipid droplet (LDs) formation, organelle involved in both lipid metabolism and inflammatory processes. …”
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