Ewing’s Sarcoma of the Lung as a Second Malignancy in Long-Term Survivor of Childhood Hodgkin’s Lymphoma: A Rare Case Report and Literature Review by Sumit Bharti, Deepak Bhasin, Gautam Goyal, Priya Sharma

“… In patients with haematologic malignancies such as lymphoma and leukaemia, significant increases in survival have been seen, due to advances in treatment strategies. …”
Get full text

Evaluation of a Telemedicine System for the Transmission of Morpho/Immunological Data Aiming at the Inclusion of Patients in a Therapeutic Trial by Jean-François Lesesve, Richard Garand

“…We present one of the first approaches of the use of telehaematology for the inclusion of patients in the GOELAMS chronic lymphocytic leukaemia 98 trial. The advantages were (1) the creation of a unique, protected, stable data bank that could be remotely consulted, (2) the use of digitized pictures which made expertise on identical documents possible, (3) the facility of computer exchanges between experts, in terms of reception as well as replying time delays. …”
Get full text

Heterogeneity in NK Cell Subpopulations May Be Involved in Kidney Cancer Metastasis by Zhengfang Liang, Fengwei Nong, Jingjie Zhao, Dalong Wei, Qianli Tang, Jian Song, Lingzhang Meng

“…Gene set enrichment analysis revealed that NK(EGR1) and NK(CAPG) were closely related to tumour metastasis, as shown by kidney cancer metastasis to Hodgkin lymphoma, T-cell leukaemia, and Ki-1+ anaplastic large cell lymphoma. …”
Get full text

Laboratory Diagnosis of Invasive Aspergillosis: From Diagnosis to Prediction of Outcome by Richard C. Barton

“…Invasive aspergillosis (IA), an infection caused by fungi in the genus Aspergillus, is seen in patients with immunological deficits, particularly acute leukaemia and stem cell transplantation, and has been associated with high rates of mortality in previous years. …”
Get full text

Mitohormesis : la clé de voûte de la résistance thérapeutique des cellules cancéreuses by Boët, Emeline, Saland, Estelle, Skuli, Sarah, Griessinger, Emmanuel, Sarry, Jean-Emmanuel

“…In this review, we are particularly interested in acute myeloid leukaemia, where mitochondrial metabolism plays a key role in response and resistance to treatment. …”
Get full text

Tumor Protective Activity of CD4+ but Not of CD8+ T Cells in DNA-Vaccinated Mice Challenged with bcr-abl-Transformed Cells by Martina Petráčková, Vincent Lučanský, Vladimír Vonka

“…In the recent past, it has repeatedly been reported that CD4 cells play an important role in the immunology of chronic myeloid leukaemia. It was therefore of interest to test their activity in an animal model using bcr-abl-transformed cells. …”
Get full text

Prognostic impact of aetiology in adult hemophagocytic lymphohistiocytosis: insights from an intensive care unit experience by Rita Noversa de Sousa, Andreia Sá Lima, Susana Viana, Filipa Guimarães, Marta Pereira, Luís Miguel Afonso

“…The first case involves natural killer-cell leukaemia, and the second, a suspected viral trigger. …”
Get full text

In Vitro 3D Models of Haematological Malignancies: Current Trends and the Road Ahead? by Carlotta Mattioda, Claudia Voena, Gianluca Ciardelli, Clara Mattu

“…Haematological malignancies comprise a diverse group of life-threatening systemic diseases, including leukaemia, lymphoma, and multiple myeloma. Currently available therapies, including chemotherapy, immunotherapy, and CAR-T cells, are often associated with important side effects and with the development of drug resistance and, consequently, disease relapse. …”
Get full text

Numb Chin Syndrome as First Symptom of Diffuse Large B-Cell Lymphoma by Mario Carbone, Francesco Della Ferrera, Lucio Carbone, Gaia Gatti, Marco Carrozzo

“…Haematological malignancies like acute lymphocytic leukaemia, Hodgkin and non-Hodgkin lymphoma, and myeloma can cause this neuropathy. …”
Get full text

Priapism in a Child from Homocystinuria from Methylenetetrahydrofolate Reductase MTHFR (C677T) Mutation by Ameer Kakaje, Ammar Fadel, Osama Hosam Aldeen, Othman Hamdan

“…It can be caused by ischaemia in sickle cell anaemia, leukaemia, trauma, drugs, or idiopathy. Homocystinuria is a rare autosomal recessive disorder that can cause hyperhomocysteinemia and hypercoagulability. …”
Get full text

Ensemble Based Box-Cox Transformation via Meta Analysis by Osman Dağ, Muhammed Ali Yılmaz

“…The proposed approach is implemented on white blood count data of leukaemia patients which are not normally distributed. …”
Get full text

Performance Augmentation of Base Classifiers Using Adaptive Boosting Framework for Medical Datasets by Durr e Nayab, Rehan Ullah Khan, Ali Mustafa Qamar

“…., global cancer map (GCM), lymphoma-I, lymphoma-II, leukaemia, and embryonal tumours. The evaluation focuses on the accuracy, precision, and efficiency of the base classifiers in the AdaBoost framework. …”
Get full text

Kolaviron and L-Ascorbic Acid Attenuate Chlorambucil-Induced Testicular Oxidative Stress in Rats by Ebenezer Tunde Olayinka, Ayokanmi Ore

“…Chlorambucil (4-[4-[bis(2-chloroethyl)amino]phenyl]butanoic acid) is an alkylating agent, indicated in chronic lymphocytic leukaemia. Kolaviron (KV), a biflavonoid complex from Garcinia kola, and L-ascorbic acid (AA) are known to protect against oxidative damage in vivo. …”
Get full text

Streptomyces-derived nano-doxorubicin: Clinical status and patents granted by Kaur Prabhjot, Bhandari Divya Dhawal, Chopra Hitesh

“…Doxorubicin (DOX) is a potent anti-cancer drug derived from Streptomyces, that is widely used for various cancers, including cancers of the ovary, urinary bladder, GI tract, breast, thyroid gland, lung, bone, kidney (nephroblastoma) and blood (leukaemia). This anthracycline antibiotic is limited by its adverse effect profile, with the main adverse effects being nausea, vomiting, alopecia, infertility, cardiotoxicity, myelosuppression and nephrotoxicity. …”
Get full text

A mathematical model of HTLV-I infection with two time delays by Xuejuan Lu, Lulu Hui, Shengqiang Liu, Jia Li

“…In this paper, we include two time delays in a mathematical model for the CD8$^+$ cytotoxicT lymphocytes (CTLs) response to the Human T-cell leukaemia virus type I (HTLV-I) infection,where one is the intracellular infection delay and the other is the immune delay to account for aseries of immunological events leading to the CTL response. …”
Get full text

Comparative study of eosinophil count and mortality outcome in children with COVID-19 infection and malignancy by U.R. Ichromy, A. Cahyadi, D. Husada

“…The most common complications found were acute lymphoblastic leukaemia (19.1 %) and carcinomas (17 %). The percentage and absolute eosinophils significantly influenced the patient’s outcome. …”
Get full text

Bovine leukosis incidence in Republic of Dagestan in 2021 by A. R. Mustafayev

“…Bovine blood was diagnostically tested for leukosis in 32 veterinary laboratories and diagnostic offices including SBI RD Republican Veterinary Laboratory. 720,489 sera were serologically tested and 7,188 (1.0%) samples were serologically positive for bovine leukaemia virus (BLV). Among the infected animals, 527 ones were subjected to haematologic testing. …”
Get full text

Critical functions for STAT5 tetramers in the maturation and survival of natural killer cells by Jian-Xin Lin, Ning Du, Peng Li, Majid Kazemian, Tesfay Gebregiorgis, Rosanne Spolski, Warren J. Leonard

“…Moreover, defective STAT5 tetramer formation could represent a cause of NK cell immunodeficiency, and interrupting STAT5 tetramer formation might serve to control NK leukaemia.…”
Get full text

Clinico-hematological and immunophenotypic profile of acute leukemia of ambiguous lineage: A four year experience from a single tertiary care centre of West India by Varnika Rai, Beena Brahmbhatt, Anurag Saha, Immanuel P. Thayakaran

“…It includes acute undifferentiated leukemia and mixed-phenotype acute Leukaemia (MPAL). Aims: The present study highlighted the clinicohematological and immunophenotypic profile of ALAL cases diagnosed in the tertiary care centre of western India. …”
Get full text

Health-related quality of life among adult patients with cancer in Uganda – a cross-sectional study by Allen Naamala, Lars E. Eriksson, Jackson Orem, Gorrette K. Nalwadda, Zarina Nahar Kabir, Lena Wettergren

“…Being an inpatient at the facility and being diagnosed with cervical cancer or leukaemia was a predictor of poor health-related quality of life. …”
Get full text