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5621
Chromosome-level and haplotype-resolved genome assembly of Bougainvillea glabra
Published 2025-01-01Get full text
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5622
Just-In-Time Adaptive Interventions to Promote Behavioral Health: Protocol for a Systematic Review
Published 2025-02-01“…ObjectiveThis study aims to systematically review the literature to describe the landscape of existing JITAIs for behavioral health at any stage of intervention development. …”
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5623
Comparative analysis of microsurgical clipping versus endovascular coiling for middle cerebral artery aneurysms: a prospective study at Ain Shams University hospitals
Published 2025-01-01“…Abstract Background The treatment landscape for intracranial aneurysms (IAs), particularly those involving the middle cerebral artery (MCA), has evolved significantly over the past two decades. …”
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5624
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5625
Identifying facilitators and barriers to culturally responsive communication for racial, ethnic, sexual, and gender minoritized patients when screened for COVID-19 vaccinations: A...
Published 2023-01-01“…The work and results from this research will be directly utilized for the development of nationally-accessible, continuing medical education materials to teach PCPs about CRC, as well as other materials to influence relevant policy changes within the healthcare landscape.…”
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5626
Assessing and optimizing the potential for climate change mitigation and carbon sequestration in urban residential green spaces: energizing sustainable cities
Published 2025-01-01“…This study contributes to the development of sustainable urban planning and landscape management practices, promoting the role of green spaces in mitigating climate change and enhancing urban resilience.…”
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5627
Role of Aging in Ulcerative Colitis Pathogenesis: A Focus on ETS1 as a Promising Biomarker
Published 2025-02-01“…Finally, the expression levels of key genes were determined in a dextran sulfate sodium (DSS)-induced UC mouse model by qRT-PCR.Results: UC samples were classified into two subtypes (1 and 2), which displayed significant differences in the immune landscape and JAK/STAT signaling pathways. A series of machine learning algorithms was used to screen two feature genes (ETS1 and IL7R) to establish the diagnostic model, which exhibited satisfactory diagnostic efficiency. …”
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5628
Seven Immune-Related Genes’ Prognostic Value and Correlation with Treatment Outcome in Head and Neck Squamous Cell Carcinoma
Published 2023-01-01“…Since immunotherapy effectively improves HNSCC patients’ survival status, it is important to continuously explore new immune-related predictive factors to accurately predict the immune landscape and clinical outcomes of individuals suffering from HNSCC. …”
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5629
Náboženská a církevně-správní situace na Chrudimsku v 18. století ve světle zpovědních výkazů
Published 2011-01-01“…Using the above- mentioned census by faith for the Chrudim region, it is possible to outline the structure of confessions of the inhabitants registered at farmsteads, manors and in towns in the mid-17th century, while taking geographic and landscape factors into account. The core of the study is based on an analysis of confession reports from 1737–1781 processed in five-year intervals. …”
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5630
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5631
A QUALITATIVE ANALYSIS OF THE INFLUENCE OF MANAGEMENT INFORMATION SYSTEMS ON ORGANIZATIONAL DECISION-MAKING PROCESSES
Published 2024-11-01“…This qualitative research examines the profound influence of Management Information Systems (MIS) on organizational decision-making processes, focusing on how these systems serve as critical tools for enhancing strategic choices in a rapidly evolving business landscape. Through a series of in-depth semi-structured interviews with key decision-makers across diverse sectors—such as technology, healthcare, retail, construction, and consulting—this study captures the nuanced perceptions and experiences of professionals who rely on MIS to navigate complex decision-making environments. …”
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5632
Demographic Profile and Clinical Characteristics of Fuchs Endothelial Corneal Dystrophy in Thai Patients: A Retrospective Cohort in a Tertiary Referral Center
Published 2025-01-01“…Trakanta Wannapanich,1,2 Vilavun Puangsricharern,1,3 Vannarut Satitpitakul,1,3 Thanachaporn Kittipibul,1,3 Kanya Suphapeetiporn4– 6 1Center of Excellence for Cornea and Stem Cell Transplantation, Department of Ophthalmology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand; 2Excellence Center for Cornea and Stem Cell Transplantation, Department of Ophthalmology, King Chulalongkorn Memorial Hospital, Thai Red Cross Society, Bangkok, Thailand; 3Department of Ophthalmology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand; 4Department of Pediatrics, Faculty of Medicine, Chulalongkorn University Bangkok, Bangkok, Thailand; 5Excellence Center for Genomics and Precision Medicine, King Chulalongkorn Memorial Hospital, The Thai Red Cross Society, Bangkok, Thailand; 6Center of Excellence for Medical Genomics, Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, Bangkok, ThailandCorrespondence: Vilavun Puangsricharern, Department of Ophthalmology, Faculty of Medicine, Chulalongkorn University, 1873, Rama 4 Road, Pathumwan, Bangkok, 10330, Thailand, Email vilavun@hotmail.com Kanya Suphapeetiporn, Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, 1873, Rama 4 Road, Pathumwan, Bangkok, 10330, Thailand, Email kanya.su@chula.ac.thPurpose: To describe the demographic profile, clinical characteristics, and treatment trends of Fuchs endothelial corneal dystrophy (FECD) in Thai patients, reflecting the evolving landscape of corneal transplantation in this region.Patients and Methods: This retrospective cohort study included 900 patients (1,743 eyes) diagnosed with FECD at a tertiary referral center in Thailand between January 2017 and June 2023. …”
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5633
Comprehensive investigation of matrix metalloproteinases in skin cutaneous melanoma: diagnostic, prognostic, and therapeutic insights
Published 2025-01-01“…We investigated the expression and promoter methylation landscape of MMPs in SKCM cell lines, revealing significant (p-value < 0.05) up-regulation of MMP1, MMP7, MMP9, MMP10, MMP11, MMP12, MMP13, MMP14, and MMP25, alongside down-regulation of MMP2, MMP3, and MMP21. …”
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5634
Co-modulation of a circular form of PCDH11Y during neuroendocrine differentiation of prostate cancer
Published 2025-02-01“…Circular RNAs (circRNAs) have emerged as potential biomarkers due to their stability and tissue-specific expression.MethodsIn this study, we investigated the circRNA landscape during neuroendocrine transdifferentiation (NED) of PC cells using the androgen-sensitive LNCaP and androgen-insensitive DU145 cell lines. …”
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5635
Refining management strategies for Lennox–Gastaut syndrome: Updated algorithms and practical approaches
Published 2025-02-01“…The revised guidance aims to improve seizure control and quality of life for patients with LGS through personalized, evidence‐based treatment strategies while addressing the challenges of accurate diagnosis and management in a rapidly evolving therapeutic landscape. Plain Language Summary Lennox–Gastaut syndrome (LGS) is a severe type of epilepsy that usually starts in childhood but continues into adulthood. …”
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5636
El rol de los actores sociales y sus implicancias en la configuración territorial de Moquehue, Neuquén, Argentina
Published 2017-12-01“…Nature has given the region a beautiful landscape that acquires value since the 70's, when the population of nearby localities began to usufruct tourism in the region. …”
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5637
The Double-Edged Sword of Third-Party Resources: Examining Use and Financial Burden of Extracurricular Tools in Medical Students [version 2; peer review: 1 approved, 2 approved wit...
Published 2025-01-01“…As students in this landscape, we aimed to review the usage, efficacy, and drawbacks of third-party resources and their financial burden on students. …”
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5638
Yoruba Epistemology, Art, Language and the Universe of Meanings: A Meta-Analysis
Published 2021-12-01“…Although short in quantity, I consider it to be loaded in quality, contents, intents, intensities, and in its ability to problematize a discourse critical to our understanding of indigenous scholarship and all its epistemological implications that span the entire landscape of the humanities. Indeed, Okediji’s pedagogy is the proverbial Yoruba drum of “ògìdìgbó” which is revealed only to the wise and the prudent, and they are the only two capable of effectively dancing to its rhythm. …”
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5639
A scoping review on the obstacles faced by beta thalassemia major patients in Pakistan- Matter of policy investment
Published 2024-11-01“…Additionally, we critically analyzed the current landscape of β-TM in Pakistan. The main challenges in β-TM care in Pakistan are suboptimal transfusion services and a poor complication management. …”
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5640
Outcomes of oncologic arthroplasty in children and adolescents with malignant limb tumors: a systematic review
Published 2024-12-01“…However, the development and refinement of chemotherapy and radiotherapy protocols, along with advances in surgical techniques and implants, have significantly altered the treatment landscape for these patients. Currently, limb-sparing oncologic arthroplasty is the preferred surgical approach for treating limb sarcomas in children. …”
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