Exploring LLMs Applications in Law: A Literature Review on Current Legal NLP Approaches by Marco Siino, Mariana Falco, Daniele Croce, Paolo Rosso

“…Artificial Intelligence (AI) is reshaping the legal landscape, with software tools now impacting various aspects of legal work. …”
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Digital therapeutics in Korea: current status, challenges, and future directions – a narrative review by Hee Jun Shin, Ik Tae Cho, Wan Suk Choi, Hong Rae Kim, Min Bong Kang, Won Jong Yang

“…The analysis focused on three primary areas: (1) the current regulatory landscape, (2) technological advancements and challenges, and (3) economic and commercial factors influencing DTx adoption in Korea. …”
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Study on SHP2 Conformational Transition and Structural Characterization of Its High-Potency Allosteric Inhibitors by Molecular Dynamics Simulations Combined with Machine Learning by Baerlike Wujieti, Mingtian Hao, Erxia Liu, Luqi Zhou, Huanchao Wang, Yu Zhang, Wei Cui, Bozhen Chen

“…Meanwhile, we explored the free energy landscape of SHP2 activation using enhanced sampling technique (meta-dynamics simulations), which provides insights into its conformational changes and activation mechanism. …”
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Effectiveness of multimedia tools in enhancing consonant-vowel-consonant reading performance and phonics interest and enthusiasm among kindergarten ESL students by Rhazhiel Dominica P. Pesebre, Rosario F. Quicho, Leila M. Collantes, Carlos N. Lamson Jr., Jupeth T. Pentang

“…In the ever-evolving landscape of education, the debate between traditional and modern instructional methods remains a focal point of discussion. …”
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Molecular dependencies and genomic consequences of a global DNA damage tolerance defect by Daniel de Groot, Aldo Spanjaard, Ronak Shah, Maaike Kreft, Ben Morris, Cor Lieftink, Joyce J. I. Catsman, Shirley Ormel, Matilda Ayidah, Bas Pilzecker, Olimpia Alessandra Buoninfante, Paul C. M. van den Berk, Roderick L. Beijersbergen, Heinz Jacobs

“…Type 3 deletions are abundant in human tumors, can dominate the deletion landscape, and are associated with DNA damage response status and treatment modality. …”
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Janus kinase inhibitor treatment for inflammatory diseases: excess or no excess risk of venous thromboembolism? by Yachar Dawudi, Samuel Benarroch, Hélène Helfer, David M. Smadja, Isabelle Mahé

“…Janus kinase inhibitors (JAKis) have revolutionized the treatment landscape for various inflammatory and autoimmune diseases since their introduction in 2012. …”
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Dynamics of perceived threat and media exposure during the COVID-19 pandemic by Talia Morstead, Nancy L. Sin, Anita DeLongis

“…The COVID-19 pandemic media landscape was characterized by an unrelenting stream of disease-related information that varied in tone, factual accuracy, and degree of ascribed certainty. …”
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Gender disparity in living organ donation: a qualitative analysis of experiences and perceptions of female donors in Pakistan by Muhammad Ishaq, Javeria Saleem, Ruhma Binte Shahzad, Mahrukh Iqbal, Abida Tehreem, Raja Sajjad Asghar, Aleena Touqeer, Gul Mehar Javaid Bukkhari

“…By acknowledging the influence of social and economic factors, strategies to create a more equitable landscape for living kidney and liver donors can be created.…”
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Expanding the structural resolution of glycosylation microheterogeneity in therapeutic proteins by salt-free hydrophilic interaction liquid chromatography tandem mass spectrometry by Yutian Gan, Steffen Lippold, John Stobaugh, Christian Schöneich, Feng Yang

“…The developed method offers a valuable tool to streamline the site-specific glycosylation analysis of glycoproteins, which is particularly important for the expanding landscape of novel therapeutic formats in the biopharmaceutical industry.…”
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Detectability of Self-lensing Flares of White Dwarfs with Compact Companions by Guy Nir, Joshua S. Bloom

“…We provide a quantitative analysis of the detectability of double-compact object self-lensing flares across the landscape of system parameters, and a qualitative discussion of survey and follow-up approaches to distinguish such flares from confounding events, such as stellar flares, satellite glints, and cosmic rays. …”
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Machine learning based identification of an amino acid metabolism related signature for predicting prognosis and immune microenvironment in pancreatic cancer by Xiaohong Liu, Xing Wang, Jie Ren, Yuan Fang, Minzhi Gu, Feihan Zhou, Ruiling Xiao, Xiyuan Luo, Jialu Bai, Decheng Jiang, Yuemeng Tang, Bo Ren, Lei You, Yupei Zhao

“…CIBERSORT and ssGSEA were harnessed to delve into the immune landscape disparities. Single-cell transcriptomics, qPCR, and Immunohistochemistry were performed to corroborate the expression levels and prognostic significance of this signature. …”
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From gut to liver: Exploring the crosstalk between gut-liver axis and oxidative stress in metabolic dysfunction-associated steatotic liver disease by Mi Zhou, Jianyu Lv, Xinli Chen, Yujie Shi, Guanqun Chao, Shuo Zhang

“…As our comprehension of MASLD deepens, it has become evident that this condition extends beyond the liver, embodying a complex, multi-systemic disease with hepatic manifestations that mirror the broader metabolic landscape. This comprehensive review delves into the critical interplay between the gut-liver axis and oxidative stress, elucidating their pivotal roles in the etiology and progression of MASLD. …”
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GNA15 predicts poor outcomes as a novel biomarker related to M2 macrophage infiltration in ovarian cancer by Qin Liu, Qin Liu, Yabing Sun, Yabing Sun, Tao Zhang, Wanrun Lin, Jing Zhang, Huijuan Zhang, Huijuan Zhang, Wenxin Zheng, Hong Xu, Hong Xu, Feng Zhou, Feng Zhou

“…This study aims to establish a novel prognostic signature and identify M2-like TAM-related biomarkers in OC using RNAseq-based transcriptome analysis.MethodsPrognostic M2-like TAM-related genes were identified through univariate Cox regression, consensus clustering, and LASSO regression. Immune landscape analysis was conducted to assess immune cell composition and immune checkpoint genes in high- and low-risk groups. …”
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RBD-displaying OMV nanovaccine boosts immunity against SARS-CoV-2 by Rang Feng, Ruo-Yi Xue, Chang Liu, Guo-Cheng Li, Yan Deng, Zhe Jin, Jing-Yi Liu, Shan-Shan Zhang, Hao Cheng, Man-Ying Guo, Quan-Ming Zou, Hai-Bo Li

“…Abstract Background Since the emergence of SARS-CoV-2, the causative agent of COVID-19, the global health landscape has confronted an unprecedented and formidable challenge. …”
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Application of Revised Universal Soil Loss Equation (Rusle) Model to Assess Soil Erosion in “Kalu Ganga” River Basin in Sri Lanka by D. L. D. Panditharathne, N. S. Abeysingha, K. G. S. Nirmanee, Ananda Mallawatantri

“…Based on erosion estimates, the basin landscape was divided into four different erosion severity classes: very low, low, moderate, and high. …”
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Identifying the Factors Affecting Student Academic Performance and Engagement Prediction in MOOC Using Deep Learning: A Systematic Literature Review by Shahzad Rizwan, Chee Ken Nee, Salem Garfan

“…The increasing reliance on Massive Open Online Courses (MOOCs) has transformed the landscape of education, particularly during the COVID-19 pandemic, where e-learning became essential. …”
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MBI-KG: A knowledge graph of structured and linked economic research data extracted from the 1937 book “Die Maschinen-Industrie im Deutschen Reich”MADATA by Renat Shigapov, Thomas Schmidt, Jan Kamlah, Irene Schumm, Jochen Streb, Sibylle Lehmann-Hasemeyer

“…By providing machine-readable, structured data from a crucial historical period, the MBI-KG facilitates novel analyses and insights into the economic and industrial landscape of early 20th-century Germany. The dataset's interoperability with other data sources and its alignment with FAIR principles further enhance its value for interdisciplinary research and long-term preservation.…”
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Latent spectral-spatial diffusion model for single hyperspectral super-resolution by Yingsong Cheng, Yong Ma, Fan Fan, Jiayi Ma, Yuan Yao, Xiaoguang Mei

“…Furthermore, the current landscape of hyperspectral SR techniques exhibits a notable deficiency in accounting for the inherent noise complexities within the realistic data, which hinders their efficacy in real-world scenarios. …”
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DAMPs prognostic signature predicts tumor immunotherapy, and identifies immunosuppressive mechanism of pannexin 1 channels in pancreatic ductal adenocarcinoma by Qianxue Wu, Qian Xiao, Qian Xiao, Xin Tang, Liuying Li, Daqiang Song, Yang Zhou, Benhua Li, Benhua Li, Guosheng Ren, Guosheng Ren, Fang Luo

“…Besides, the prognosis and immune landscape in up-regulated DAMPs expression subtypes was poor. …”
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Characterization of tumor prognosis and sensitive chemotherapy drugs based on cuproptosis-related gene signature in ovarian cancer by Wei Tan, Fangfang Dai, Qinyu Ci, Zhimin Deng, Hua Liu, Yanxiang Cheng

“…Ultimately, our analysis compared the two groups across various dimensions, including clinical characteristics, tumor progression, metabolism-related pathways, immune landscape, and drug sensitivity. Results MTF1 and LIAS were identified as protective factors in ovarian cancer, with patients in the higher risk group being significantly associated with poorer survival. …”
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