A sustainable approach in pumpkin seed oil processing line: Recent advances in pumpkin seed oil and oil processing by-products by Guoqiang Zhang, Jingbo Guo, Jinying Guo

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Implementing a nurse-enabled, integrated, shared-care model involving specialists and general practitioners in early breast cancer post-treatment follow-up (EMINENT): a single-centre, open-label, phase 2, parallel-group, pilot, randomised, controlled trialResearch in context by Raymond J. Chan, Fiona Crawford-Williams, Chad Yixian Han, Lee Jones, Alexandre Chan, Daniel McKavanagh, Marissa Ryan, Christine Carrington, Rebecca L. Packer, Megan Crichton, Nicolas H. Hart, Emma McKinnell, Melissa Gosper, Juanita Ryan, Bethany Crowe, Ria Joseph, Carolyn Ee, Jane Lee, Steven M. McPhail, Katharine Cuff, Laisa Teleni, Jon Emery

“…Methods: In this single-centre, open-label, phase II, pilot, randomised, controlled trial, individuals diagnosed with breast cancer (Stage 0–III) were randomised 1:1 to either usual care or intervention, which includes a 1) Specialist Nurse Consultation to co-develop a survivorship care plan (SCP), 2) Pharmacist Consultation, 3) Case Conference with General Practitioner (GP), and 4) shared follow-up care arrangements. …”
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Low & Anaplastic Grade Glioma Umbrella Study of MOlecular Guided TherapieS (LUMOS-2): study protocol for a phase 2, prospective, multicentre, open-label, multiarm, biomarker-directed, signal-seeking, umbrella, clinical trial for recurrent IDH mutant, grade 2/3 glioma by Marshall Pitz, Eng-Siew Koh, Elizabeth H Barnes, Lucille Sebastian, Mandy L Ballinger, David M Thomas, Christopher O'Callaghan, John Simes, Hui K Gan, Sonia Yip, Hao-Wen Sim, Desma Spyridopoulos, Richard De Abreu Lourenco, Cynthia Hawkins, Kristen McParland, Benjamin Kong, Subotheni Thavaneswaran, Patrick J Wheeler

“…This study aims to improve outcomes by molecular profiling of patients at relapse, then matching them with the best available drug based on their molecular profile, maximising the chances of patient benefit while simultaneously testing multiple novel drugs.Methods and analysis Low & Anaplastic Grade Glioma Umbrella Study of MOlecular Guided TherapieS (LUMOS-2) will be an international, phase 2, multicentre, open-label, biomarker-directed, umbrella clinical trial for recurrent isocitrate dehydrogenase mutant, histologically grade 2/3 gliomas. …”
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Therapy of genomic unstable solid tumours (WHO grade 3/4）in clinical stage III/IV using individualised neoantigen tumour peptides-INP trial (individualised neoantigen tumour peptides immunotherapy): study protocol for an open-label, non-randomised, prospective, single-arm trial by Ling Wang, Xia Chen, Juan Zhao, Jiaxi Tang, Wanyan Tang, Bin Liao, Weiqi Nian

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Panitumumab plus 5-fluorouracil and folinic acid or 5-fluorouracil and folinic acid alone as maintenance therapy in RAS wild-type metastatic colorectal cancer (PanaMa, AIO KRK 0212): final efficacy analysis of a randomised, open-label, phase 2 trialResearch in context by Arndt Stahler, Meinolf Karthaus, Stefan Fruehauf, Ullrich Graeven, Lothar Müller, Ludwig Fischer von Weikersthal, Karel Caca, Eray Goekkurt, Alexej Ballhausen, Greta Sommerhäuser, Annabel H.S. Alig, Swantje Held, Armin Jarosch, David Horst, Anke Reinacher-Schick, Stefan Kasper, Volker Heinemann, Sebastian Stintzing, Tanja Trarbach, Dominik P. Modest

“…Methods: In this final phase 2 trial analysis, adult mCRC patients responding to six cycles of FU/FA, oxaliplatin and panitumumab were randomized (1:1, open-label) to maintenance of either FU/FA + panitumumab or FU/FA alone. …”
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HEMŞİRELER ARASINDA DAMGALAMA OLGUSU ÜZERİNE KEŞİFSEL BİR ÇALIŞMA by Ramazan Erdem, Sümeyye Özmen

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Implicit Forms of Ethnic Insult for Europeans (as Found in Rhyming Slang) by E. Y. Gorshunova, Y. V. Gorshunov

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An eCUA model for integrated computing power and decentralized digital identity and a new business system supporting information framework by Wen QIAO, Xiaozheng WANG, Gan REN, Aidong YANG, Shoufeng WANG, Peng WANG, Xiaozhou YE, Ye OUYANG

Subjects: “…decentralized identity labeling…”
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The grapevine ABC transporter B family member 15 is a trans-resveratrol transporter out of grapevine cells by Ascensión Martínez-Márquez, Ascensión Martínez-Márquez, Viviana Martins, Susana Sellés-Marchart, Susana Sellés-Marchart, Hernâni Gerós, Purificación Corchete, Roque Bru-Martínez, Roque Bru-Martínez, Roque Bru-Martínez

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Associations between cerebral blood flow and progression of white matter hyperintensities by Siriluk Thammasart, Danielle J. Harvey, Pauline Maillard, Charles DeCarli, Corinne A. Donnay, Gregory J. Wheeler, Audrey P. Fan, Audrey P. Fan

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Depth-dependent PD-L1 sampling of head and neck squamous cell carcinoma (HNSCC) – implications for PD-1/PD-L1 checkpoint inhibitor immunotherapy by Madhusudan Roy, Jing-Tang Lin, Sohidul Mondal, Mei-Chun Lin, Chih-Yu Leu, Yen-Lin Huang, Chen-Yuan Dong, Pei-Jen Lou

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Enhanced YOLOv10 Framework Featuring DPAM and DALSM for Real-Time Underwater Object Detection by Suthir Sriram, Aburvan P., Arun Kaarthic T. P., Nivethitha Vijayaraj, Thangavel Murugan

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Association between carotid artery hemodynamics and neurovascular coupling in cerebral small vessel disease: an exploratory study by Peng Zeng, Bang Zeng, Xiaohua Wang, Feiyue Yin, Binglan Li, Lisha Nie, Lin Tian, Dan Luo, Yongmei Li

Subjects: “…multi-delay arterial spin labeling…”
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Study on its application and unstable risk subarea estimation method of mountainous traffic engineering’s spoil ground by Jihong Zhang, Zhongji Dong, Xiaotao Yin, Min Yang

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Farklı Şekilde Etiketlenen Likert Tipi Ölçeklerin Ölçme Değişmezliğine Etkisinin İncelenmesi by Meltem Yurtçu, Nuri Doğan, Ceylan Gündeğer

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Pathway Of Low Anterior Resection syndrome (LARS) relief after Surgery (POLARiS): protocol for an international, open-label, multi-arm, phase 3 randomised superiority trial within a cohort, with economic evaluation, process evaluation and qualitative sub-study, to explore the natural history of LARS and compare transanal irrigation and sacral neuromodulation to optimised conservative management for people with major LARS following a high or low anterior resection for colorectal cancer by Deborah D Stocken, Charles H Knowles, Jared Torkington, David Jayne, Julie Hepburn, Laura Knight, Neil Corrigan, Julie Cornish, Katie Gordon, Ashley Douglas, Kate Wilson, Megan Dale, Julie Croft, Christina Lloydwin, Alexandra Harriet Coxon-Meggy, Judith White, Alun Meggy, Aaron Quyn, Emily Farrow, Kheng-Seong Ng, Hannah Mather, Huey Yi Chong, Betty Tan, Ralph Powell, Andrea Warwick

“…Despite this, little is known about the natural history and there is poor evidence to support current treatment options.Methods and analysis The objectives of POLARiS are to explore the natural history of LARS and to evaluate the clinical and cost-effectiveness of transanal irrigation (TAI) or sacral neuromodulation (SNM) compared with optimised conservative management (OCM) for people with major LARS.POLARiS is a prospective, international, open-label, multi-arm, phase 3 randomised superiority trial within a cohort design, with internal pilot phase, qualitative sub-study, process evaluation and economic evaluation. …”
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La labellisation, (re)qualification ou disqualification des marges ? Le cas du safran à Taliouine (Anti-Atlas, Maroc) by Mari Oiry Varacca

“…This article examines how agricultural products from marginalised mountain regions in Morocco manage to get labels. The country’s public authorities present labelling as a new way of requalifying areas that have previously been left behind. …”
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The interpretation and translation of Galatians 5:12 by D. F. Tolmie

“… As is evident from commentaries on Galatians and from various English translations, scholars do not agree on the meaning, rhetorical labelling and translation of the wish expressed by Paul in Galatians 5:12. …”
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Food-based indices for the assessment of nutritive value and environmental impact of meals and diets: A systematic review protocol. by Eva-Leanne Thomas, David Livingstone, Anne P Nugent, Jayne V Woodside, Paul Brereton

“…Though these challenges are multifaceted, shifting to healthy dietary choices from sustainable food systems is one solution. Food-based labelling is a common public-health strategy aimed at influencing consumption practices, primarily displaying front-of-pack nutrition labelling to encourage healthier choices. …”
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Da sociologia do desvio à criminologia crítica: os indígenas de Mato Grosso do Sul como outsiders by Igor Henrique da Silva Santelli, Antonio Guimarães Brito

“…In first part, it deals with the sociological approaches of Goffman, Becker and Elias, who point out the reasons and effects of stigmatization, labelling and marginalization and explain elementary fea- tures of the relationship between established people and outsiders. …”
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