Results of a Randomized, Open-Label, Clinical Trial Investigating the Effects of Supplementation with Heracleum persicum Extract as an Adjunctive Therapy for Dyslipidemia by Yunes Panahi, Bahram Pishgoo, Fatemeh Beiraghdar, Zahra Mohammadi Araghi, Amirhossein Sahebkar, Ehsan Abolhasani

“…In a randomized, open-label, clinical trial, 100 dyslipidemic subjects were randomly assigned to: (1) H. persicum group (n = 50, completers = 18), receiving H. persicum extract (500 mg/day) + atorvastatin (10 mg/day) for 8 weeks, or (2) atorvastatin group (n =50, completers= 34), receiving only atorvastatin (20 mg/day) for 8 weeks. …”
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Intravenous Oxycodone versus Intravenous Morphine in Cancer Pain: A Randomized, Open-Label, Parallel-Group, Active-Control Study by Kyung-Hee Lee, Jung-Hun Kang, Ho-Suk Oh, Moon-Ki Choi, Byoung-Yong Shim, Young-Jun Eum, Hye-Jeong Park, Jin-Hyong Kang

“…A 5-day, randomized, open-label, exploratory study at 6 sites in the Republic of Korea. …”
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Efficacy and Tolerability of a Combined Moxifloxacin/Dexamethasone Formulation for Topical Prophylaxis in Phacoemulsification: An Open-Label Single-Arm Clinical Trial by Cesar Ramon G. Espiritu, Mary Ellen A. Sy, Tommee Lynne G. Tayengco

“…Methods. A 15-day, open-label, single-arm trial of 64 patients for phacoemulsification with intraocular lens (IOL) implantation is described. …”
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Edge-Preserving Probabilistic Downsampling for Reliable Medical Segmentation in Resource-Constrained Environments by Shahzad Ali, Yu Rim Lee, Soo Young Park, Won Young Tak, Soon Ki Jung

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Les installations immersives muséalisées : un défi muséographique. Connaître l’expérience des visiteurs pour adapter l’accompagnement muséal. by Elizabeth Desbans

Subjects: “…labels…”
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Consumer acceptance of protein beverage ingredients: Less is more by D. Rovai, M.E. Watson, D.M. Barbano, M.A. Drake

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Evaluation of the Gly-Phe-Lys Linker to Reduce the Renal Radioactivity of a [64Cu]Cu-Labeled Multimeric cRGD Peptide by Zhao-Hui Jin, Mélissa Degardin, Takako Furukawa, Tomoya Uehara, Atsushi B. Tsuji, Hiroyuki Suzuki, Hidekatsu Wakizaka, Aya Sugyo, Winn Aung, Hisashi Suzuki, Kotaro Nagatsu, Ming-Rong Zhang, Pascal Dumy, Didier Boturyn, Tatsuya Higashi

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Development of ¹¹¹In-Labeled Monoclonal Antibodies Targeting SFTSV Structural Proteins for Molecular Imaging of SFTS Infectious Diseases by SPECT by Takeshi Fuchigami, Mya Myat Ngwe Tun, Yusuke Tanahara, Kodai Nishi, Sakura Yoshida, Kazuma Ogawa, Morio Nakayama, Daisuke Hayasaka

“…This study evaluated the potential of ¹¹¹In-labeled anti-SFTSV antibodies targeting SFTSV structural proteins as single-photon emission computed tomography (SPECT) imaging agents for the selective visualization of SFTSV-infected sites. …”
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High resolution multi-delay arterial spin labeling with self-supervised deep learning denoising for pediatric choroid plexus perfusion MRI by Qinyang Shou, Chenyang Zhao, Xingfeng Shao, Megan M Herting, Danny JJ Wang

“…CP perfusion has been studied using multi-delay arterial spin labeling (MD-ASL) in adults but not in pediatric populations due to the challenge of small CP size in children. …”
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Antiviral efficacy of fluoxetine in early symptomatic COVID-19: an open-label, randomised, controlled, adaptive platform trial (PLATCOV)Research in context by Podjanee Jittamala, Simon Boyd, William H.K. Schilling, James A. Watson, Thundon Ngamprasertchai, Tanaya Siripoon, Viravarn Luvira, Elizabeth M. Batty, Phrutsamon Wongnak, Lisia M. Esper, Pedro J. Almeida, Cintia Cruz, Fernando R. Ascencao, Renato S. Aguiar, Najia K. Ghanchi, James J. Callery, Shivani Singh, Varaporn Kruabkontho, Thatsanun Ngernseng, Jaruwan Tubprasert, Wanassanan Madmanee, Kanokon Suwannasin, Amornrat Promsongsil, Borimas Hanboonkunupakarn, Kittiyod Poovorawan, Manus Potaporn, Attasit Srisubat, Bootsakorn Loharjun, Walter R.J. Taylor, Farah Qamar, Abdul Momin Kazi, M. Asim Beg, Danoy Chommanam, Sisouphanh Vidhamaly, Kesinee Chotivanich, Mallika Imwong, Sasithon Pukrittayakamee, Arjen M. Dondorp, Nicholas P.J. Day, Mauro M. Teixeira, Watcharapong Piyaphanee, Weerapong Phumratanaprapin, Nicholas J. White

“…Methods: PLATCOV is an open-label, multicentre, phase 2, randomised, controlled, adaptive pharmacometric platform trial running in Thailand, Brazil, Pakistan, and Laos. …”
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Estimation of Willingness to Pay for Life Cycle Eco-label Using Spike Model (A Case Study of Fresh Packaged Agricultural Products) by samaneh heydari, Leili Abolhassani, Morteza Molaei, Ali Firoz-zare

Subjects: “…dichotomous response method eco-label design…”
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Transcranial photobiomodulation for reducing symptoms of autism spectrum disorder and modulating brain electrophysiology in children aged 2–7: an open label study by Yuli Fradkin, Joaquin A. Anguera, Alexander J. Simon, Luis De Taboada, Eugenia Steingold

“…BackgroundSmall pilot studies have indicated that transcranial photobiomodulation (tPBM) may help alleviate symptoms of neurological conditions like depression, traumatic brain injury and Autism Spectrum Disorder (ASD).ObjectiveTo examine the effect of tPBM on the behavioral symptoms of ASD and brain electrophysiology in children aged 2–7.MethodsWe conducted an open label, one-arm study with 23 participants, aged 2–7, previously diagnosed with ASD. …”
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Fabrication and evaluation of a portable and reproducible quartz crystal microbalance immunochip for label-free detection of β-lactoglobulin allergen in milk products by Mingfei Pan, Liping Hong, Jingying Yang, Xiaoqian Xie, Kaixin Liu, Shuo Wang

“…In this study, a label-free, portable and reproducible immunochip based on quartz crystal microbalance (QCM) was developed for the qualitative detection of β-lactoglobulin (β-LG), an allergen, in milk products. …”
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Utilisation of the Innovative [18F]-Labelled Radiotracer [18F]-BIBD-071 Within HR+ Breast Cancer Xenograft Mouse Models by Di Fan, Xin Wang, Xueyuan Ling, Hongbin Li, Lu Zhang, Wei Zheng, Zehui Wu, Lin Ai

“…The MCF-7 cell line, which is hormone receptor-positive (HR+), was used in the assessment of the novel [18F]-labelled radiotracer [18F]BIBD-071 via positron emission tomography (PET) imaging of an HR+ breast cancer xenograft model. …”
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Trial protocol of an open-label pilot study of oral naltrexone–bupropion combination pharmacotherapy for the treatment of methamphetamine use disorder (the NABU trial) by Jonathan Brett, Paul S Haber, Nicholas Lintzeris, Didier Jutras-Aswad, Nadine Ezard, Brendan Clifford, Krista J Siefried, Adrian John Dunlop, Liam Acheson, Carl Moller, Michael Christmass, Kirsten Morley, Steven Shoptaw, Madhukar H Trivedi

“…Here, we report a trial protocol for an oral formulation of combined naltrexone and bupropion.Methods and analysis This single-arm, open-label pilot study will assess the safety and feasibility of oral naltrexone and bupropion (40 mg/450 mg daily in divided doses) in adults with methamphetamine use disorder. …”
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Imaging Collagen in Intact Viable Healthy and Atherosclerotic Arteries Using Fluorescently Labeled CNA35 and Two-Photon Laser Scanning Microscopy by Remco T.A. Megens, Mirjam G.A. oude Egbrink, Jack P.M. Cleutjens, Marijke J.E. Kuijpers, Paul H.M. Schiffers, Maarten Merkx, Dick W. Slaaf, Marc A.M.J. van Zandvoort

“…Two-photon microscopy was used for imaging. CNA35/OG488 labeling in healthy elastic arteries was compared with collagen type I, III, and IV antibody labeling in histologic sections. …”
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Label-free (fluorescence-free) sensing of a single DNA molecule on DNA origami using a plasmon-enhanced WGM sensor by Ghamari Shahin, Chiarelli Germán, Kołątaj Karol, Subramanian Sivaraman, Acuna Guillermo P., Vollmer Frank

“…The integration of DNA origami structures with opto-plasmonic whispering gallery mode (WGM) sensors offers a significant advancement in label-free biosensing, overcoming the limitations of traditional fluorescence-based techniques, and providing enhanced sensitivity and specificity for detecting DNA hybridization events. …”
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Efficacy of 2‐Mercaptoethane Sulfonate Sodium (MESNA) in the Prevention of Pancreatitis After Endoscopic Retrograde Cholangiopancreatography: A Randomized Open Label Trial by Amir Sadeghi, Hesamoddin Samar, Mohammad Abbasinazari, Parvaneh Mohammadi, Ali Abazarikia, Shadi Ziaie

“…The present clinical trial evaluated whether adding intravenous mesna to rectal indomethacin could prevent or alleviate PEP. Methods An open‐labeled clinical trial was done on 698 participants undergoing endoscopic retrograde cholangiopancreatography (ERCP). …”
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Clozapine for Treatment-Resistant Disruptive Behaviors in Youths With Autism Spectrum Disorder Aged 10-17 Years: Protocol for an Open-Label Trial by André Luiz Schuh Teixeira da Rosa, Marina Ribeiro Barreto da Costa, Gabriela Bezerra Sorato, Felipe de Moura Manjabosco, Érica Bonganhi de Bem, Lucas Dellazari, Arthur Bezerra Falcão, Lucas de Oliveira Cia, Olivia Sorato Bezerra, Rogério Boff Borges, Luis Augusto Rohde, Ana Soledade Graeff-Martins

“…Our study represents the first open-label trial to explore the anti-aggressive effects of clozapine in this specific demographic, marking a pioneering step in clinical investigation. …”
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Identifying falsified COVID-19 vaccines by analysing vaccine vial label and excipient profiles using MALDI-ToF mass spectrometry by Benediktus Yohan Arman, Rebecca Clarke, Tehmina Bharucha, Laura Gomez Fernandez, John Walsby-Tickle, Michael Deats, Sara Mosca, Qianqi Lin, Sneha Banerjee, Shrikrishna R. Chunekar, Kundan D. Patil, Sunil Gairola, Susanna Dunachie, Hamid A. Merchant, Robert Stokes, Rutendo Kuwana, Alexandrine Maes, Jean-Philippe Charrier, Fay Probert, Céline Caillet, Pavel Matousek, James McCullagh, Paul N. Newton, Nicole Zitzmann, Bevin Gangadharan

“…We demonstrate for the first time that analysis of spectra from the vaccine vial label and its adhesive could be used as a novel approach to detect falsified vaccines. …”
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