Proteomic profiling of bronchoalveolar lavage fluid uncovers protein clusters linked to survival in idiopathic forms of interstitial lung disease by Linh T. Ngo, Michaella J. Rekowski, Devin C. Koestler, Takafumi Yorozuya, Atsushi Saito, Imaan Azeem, Alexis Harrison, M. Kristen Demoruelle, Jonathan Boomer, Bryant R. England, Paul Wolters, Philip L. Molyneaux, Mario Castro, Joyce S. Lee, Joshua J. Solomon, Koji Koronuma, Michael P. Washburn, Scott M. Matson

“…Proteomic profiling of BALF was conducted using label-free quantitative methods. Unsupervised cluster analyses identified protein expression profiles that were then analysed to predict survival outcomes and investigate associated pathways. …”
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Tetracyclines in Rheumatoid Arthritis: Dual Anti-Inflammatory and Immunomodulatory Roles, Effectiveness, and Safety Insights by Mislav Radić, Andrej Belančić, Hana Đogaš, Marijana Vučković, Andrea Gelemanović, Andrea Faour, Ivan Vlak, Josipa Radić

“…Current guidelines for RA management do not explicitly recommend tetracyclines due to these limitations, although off-label use may be considered in specific cases. The use of tetracycline for RA is restricted by drug interactions causing bacterial resistance alongside unpredictable patient responses, hence the necessity for prudence in its prescription within a clinical setting. …”
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Immunohistochemical Profile of p62/SQSTM1/Sequestosome-1 in Human Low- and High-Grade Intracranial Meningiomas by Antonio Ieni, Cristina Pizzimenti, Vincenzo Fiorentino, Mariausilia Franchina, Antonino Germanò, Giovanni Raffa, Maurizio Martini, Guido Fadda, Giovanni Tuccari

“…However, intranuclear vacuoles have been ultrastructurally observed in meningiomas, and they were labelled by p62 antibodies. Therefore, in the present study, we have investigated p62 immunohistochemical pattern in a cohort of 133 cases representative of low- and high-grade meningiomas, to verify if p62 expression may be related to clinicopathological data, thus achieving a potential prognostic role. …”
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KE-RSIC: Remote Sensing Image Captioning Based on Knowledge Embedding by Kangda Cheng, Erik Cambria, Jinlong Liu, Yushi Chen, Zhilu Wu

“…We retrieve reports with similar label distributions to the input and then extract entities and relationships from the retrieved reports using a relation extractor. …”
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Targeting the Vasculature of Colorectal Carcinoma with a Fused Protein of (RGD)3-tTF by Zheng-jie Huang, Yilin Zhao, Wei-yuan Luo, Jun You, Shui-wen Li, Wen-cheng Yi, Sheng-yu Wang, Jiang-hua Yan, Qi Luo

“…The bioactivities of (RGD)3-tTF including coagulation activity, FX activation, and binding with integrin αvβ3 were performed. The fluorescent labeled (RGD)3-tTF was intravenously injected into tumor-bearing mice and traced in vivo. …”
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Exploring the exoproteome of the parasitic nematode Anisakis simplex (s. s.) and its impact on the human host – an in vitro cross-talk proteomic approach by Robert Stryiński, Robert Stryiński, Ewa Fiedorowicz, Jesús Mateos, Aneta Andronowska, Elżbieta Łopieńska-Biernat, Mónica Carrera

“…To achieve this goal, the shotgun proteomics method based on isobaric mass labeling (via tandem mass tags; TMT) was used with a combination of nano high-performance liquid chromatography (nLC) coupled with an LTQ-Orbitrap Elite mass spectrometer. …”
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Combining a Standardized Growth Class Assessment, UAV Sensor Data, GIS Processing, and Machine Learning Classification to Derive a Correlation with the Vigour and Canopy Volume of... by Ronald P. Dillner, Maria A. Wimmer, Matthias Porten, Thomas Udelhoven, Rebecca Retzlaff

“…To address these problems, based on a standardized growth class assessment, labeled ground truth data of precisely located grapevines were predicted with specifically selected Machine Learning (ML) classifiers (Random Forest Classifier (RFC), Support Vector Machines (SVM)), utilizing multispectral UAV (Unmanned Aerial Vehicle) sensor data. …”
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Proportional Assist Ventilation for Minimizing the Duration of Mechanical Ventilation (the PROMIZING study): update to the statistical analysis plan for a randomized controlled tri... by Karen J. Bosma, Myriam Lafreniere-Roula, Arlene Jiang, Anna Heath, Yongdong Ouyang, Kaitlyn Wade, Pingzhao Hu, Karen E. A. Burns, Claudio M. Martin, Yoanna Skrobik, Sorcha Mulligan, Kevin E. Thorpe, Laurent Brochard, members of the Canadian Critical Care Trials Group and the REVA Network

“…Methods/design The Proportional Assist Ventilation for Minimizing the Duration of Mechanical Ventilation (PROMIZING) study is a multi-center, open-label, randomized controlled trial designed to determine if ventilation with proportional assist ventilation with load-adjustable gain factors will result in a shorter duration of time spent on mechanical ventilation compared to ventilation with pressure support ventilation for patients with acute respiratory failure. …”
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A Hybrid Efficient U-Net Framework for Detection of Anterior Belly of the Digastric Muscle on Ultrasonography by Sule Erdem, Suheda Erdem, Muammer Turkoglu, Abdulkadir Sengur, Nebras M. Sobahi

“…The visual results showed that the segmentation masks of the MultiResUNet-Fusion models provided predictions close to the real labels, and all models generally localized the region of interest accurately. …”
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Research on entity recognition and alignment of APT attack based on Bert and BiLSTM-CRF by Xiuzhang YANG, Guojun PENG, Zichuan LI, Yangqi LYU, Side LIU, Chenguang LI

“…Thirdly, the CRF algorithm is utilized to decode the relationship between the output predicted labels and generate the optimal label sequence. Finally, the entity alignment method based on semantic similarity and Birch is constructed, which can improve the quality of the extracted APT attack knowledge through knowledge matching and merging into the infobox of each APT organization. …”
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Semantic Segmentation Method for High-Resolution Tomato Seedling Point Clouds Based on Sparse Convolution by Shizhao Li, Zhichao Yan, Boxiang Ma, Shaoru Guo, Hongxia Song

“…Tomato seedling point clouds from the Pheno4D dataset labeled into semantic classes of ‘leaf’, ‘stem’, and ‘soil’ are applied for the semantic segmentation. …”
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Improved ChIP Sequencing for H3K27ac Profiling and Super-Enhancer Analysis Assisted by Fluorescence-Activated Sorting of Formalin-Fixed Paraffin-Embedded Tissues by Nenggang Jiang, Zhihao Wen, Huan Tao, Hongyan Liao

“…Essential steps included single cell preparation, heat treatment enhancing antigen retrieval and labeling, cell sorting, chromatin shearing, ChIP and NGS. …”
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Radiofrequency ablation as a method of choice for the treatment of lower extremity varicose veins disease by O. Yu. Atamaniuk, V. D. Skrypko, V. M. Atamaniuk

“…Materials and methods. An open-label, prospective study of the effectiveness of a modified RFA protocol for the treatment of 210 consecutive patients with clinical grade C2-C6 of LEVVD was conducted. …”
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Dual‐fluorescence imaging and automated trophallaxis detection for studying multi‐nutrient regulation in superorganisms by Lior Baltiansky, Einav Sarafian‐Tamam, Efrat Greenwald, Ofer Feinerman

“…Our dual‐fluorescence imaging set‐up is designed to track two food sources, each labelled with a different fluorophore, as they are disseminated throughout a freely behaving colony of individually tagged ants. …”
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Study on Management of Blood Transfusion Therapy in Patients with Hereditary Spherocytosis by Shiyue Ma, Lingjian Tang, Chaoli Wu, Hui Tang, Xue Pu, Jinhong Niu

“…The fluorescence of EMA-labeled red blood cell (RBC) was decreased. DNA sequencing showed that His54Pro, Leu1858Val, and 6531-12C>T compound heterozygous mutations were present in the SPTA1 gene of patient I-1, Arg344Gln and c.609+86G>A heterozygous mutations were present in the SLC4A1 gene of patient II-1, and Leu2032Pro homozygous mutation was present in the SPTB gene of patient III-1. …”
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A New Approach to Determine the Total Airborne N Input into the Soil/Plant System Using 15N Isotope Dilution (ITNI): Results for Agricultural Areas in Central Germany by Rolf W.B. Russow, Frank Bahme, Heinz-Ulrich Neue

“…A soil/plant system is labeled with [15N]ammonium-[15N]nitrate and the total input of airborne N is calculated from the dilution of this tracer by N from the atmosphere. …”
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Honokiol Provides Cardioprotection from Myocardial Ischemia/Reperfusion Injury (MI/RI) by Inhibiting Mitochondrial Apoptosis via the PI3K/AKT Signaling Pathway by Linhua Lv, Qiuhuan Kong, Zhiying Li, Ying Zhang, Bijiao Chen, Lihua Lv, Yubi Zhang

“…Apoptotic levels were detected using terminal deoxynucleotidyl transferase dUTP nick-end labeling (TUNEL) staining. Electron microscopy was utilized to identify mitochondrial damage. …”
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Prevalence and Correlates of Hypertension Unawareness among Lebanese Adults: The Need to Target Those “Left Behind” by Fatima Ghaddar, Lama Hammad, Rania A. Tohme, Tamar Kabakian-Khasholian, Nahla Hwalla, Abla M. Sibai

“…Those responding negatively to the face-to-face interview question “whether they had ever been told by a health worker that they have hypertension” were labelled as “apparently healthy.” Results. Overall prevalence of hypertension was 30.7%. …”
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Assessing the possibility of using portable and stationary non-mydriatic fundus cameras for diabetic retinopathy screening assisted by an artificial intelligence-based software pla... by A.O. Nevska, O.A. Pohosian, K.O. Goncharuk, O.O. Chernenko, I.V. Hymanyk, A.R. Korol

“…Material and Methods: In this prospective, open-label study, 609 subjects (1218 eyes) with either diagnosed diabetes mellitus (DM) or risk factors for DM were divided into two groups depending on whether the fundus camera was stationary or portable. …”
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Assessment of renal insufficiency in patients with renal artery stenosis by multiparametric magnetic resonance imaging by Long Zhao, Feng-Bo Xu, Jia-Yi Liu, Shuang Li, Nan Zhang, Zhong-Hua Sun, Guo-Qin Wang, Lei Xu

“…The scanning sequences included arterial spin labeling, phase contrast MRI, diffusion weighted imaging, T1 mapping, and blood oxygen level-dependent MRI. …”
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