Predictors and Outcomes of Hematoma Expansion and Neurological Decline in Intracerebral Hemorrhage: A Multisite Mobile Stroke Unit Study by Asish K. Gulati, Tianwen Ma, Isaiah Rolle, Ryan Peterson, Bianca Pirlog, Justine Chen, Megan Heckathorn, Jonathan Ratcliff, Nicolas Bianchi, Carol Fleming, Michael Frankel, James Grotta, Ritvij Bowry, Stephanie Parker, William Hicks, Digvijaya Navalkele

“…Background Hemorrhagic stroke, particularly intracerebral hemorrhage, is one of the leading causes of permanent disability worldwide. …”
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Prehospital scale to differentiate intracerebral hemorrhage from large-vessel occlusion patients: a prospective cohort study by A. Freixa-Cruz, G. Jimenez-Jimenez, G. Mauri-Capdevila, Y. Gallego-Sánchez, A. García-Díaz, R. Mitjana-Penella, M. Paul-Arias, C. Pereira-Priego, E. Ruiz-Fernández, S. Salvany-Montserrat, A. Sancho-Saldaña, E. San-Pedro-Murillo, E. Saureu, D. Vázquez-Justes, Francisco Purroy

Subjects: “…Intracerebral hemorrhage…”
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Liangxue Tongyu Prescription exerts neuroprotection by regulating the microbiota-gut-brain axis of rats with acute intracerebral hemorrhage by Yingying Sun, Dandan Zhou, Anlan Liu, Yu Zhou, Yang Zhao, Yuan Yuan, Weifeng Guo, Jianxiang Li

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Exploring the associations of gut microbiota with inflammatory and the early hematoma expansion in intracerebral hemorrhage: from change to potential therapeutic objectives by Haixiao Jiang, Wei Zeng, Fei Zhu, Xiaoli Zhang, Demao Cao, Aijun Peng, Hongsheng Wang

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The predictive value of optic nerve sheath diameter measurement via ultrasound for intracerebral hemorrhage complicated by cerebral-cardiac syndrome by Wei-Ze Fan, Jun-Rong Jiang, Hui-Ling Zang, Hui Cheng, Xiao-Hui Shen, Wen-Juan Yang, Hui Wang, Li-Xing Jing

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Implementation of a goal-directed Care Bundle for intracerebral hemorrhage: Results of embedded process evaluation in the INTERACT3 trial. by Menglu Ouyang, Anila Anjum, Francisca Gonzalez Mc Cawley, Mohammad Wasay, Lu Ma, Xin Hu, Xiaoying Chen, Alejandra Malavera, Xi Li, Paula Muñoz Venturelli, H Asita de Silva, Nguyen Huy Thang, Kolawole W Wahab, Jeyaraj D Pandian, Octavio M Pontes-Neto, Carlos Abanto, Venessa Cano-Nigenda, Antonio Arauz, Chao You, Stephen Jan, Lili Song, Craig S Anderson, Hueiming Liu, INTERACT3 Investigators

“…The third, stepped-wedge, cluster-randomized, Intensive Care Bundle with Blood Pressure Reduction in Acute Cerebral Hemorrhage Trial (INTERACT3), has shown that a goal-directed multi-faceted Care Bundle incorporating protocols for the management of physiological variables was safe and effective for improving functional recovery in a broad range of patients with acute intracerebral hemorrhage (ICH). The INTERACT3 Care Bundle included time- and target-based protocols for the management of early intensive lowering of systolic blood pressure (SBP, target <140mmHg), glucose control (target 6.1-7.8 mmol/L in those without diabetes and 7.8-10.0 mmol/L in those with diabetes), anti-pyrexia treatment (target body temperature ≤37.5°C), and the rapid reversal of warfarin-related anticoagulation (target international normalized ratio <1.5). …”
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PPAR-γ Promotes Hematoma Clearance through Haptoglobin-Hemoglobin-CD163 in a Rat Model of Intracerebral Hemorrhage by Gaiqing Wang, Tong Li, Shu-na Duan, Liang Dong, Xin-gang Sun, Fang Xue

“…PPAR-γ is a transcriptional factor which is associated with promoting hematoma clearance and reducing neurological dysfunction after intracerebral hemorrhage (ICH). Haptoglobin- (Hp-) hemoglobin- (Hb-) CD163 acts as a main pathway to Hb scavenging after ICH. …”
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Spatiotemporal transcriptome and scRNA sequencing analysis reveals that IKFZ1‐mediated microglia underlies a therapy for intracerebral hemorrhage by Wenqiao Qiu, Jie Tian, Gao Mou, Lili Guo, Tao Xu, Wei Liu, Jianwei Zhu, Yi Zhang, Xiaolin Hou, Yao Xie, Huan Xiong, Xinda Li, Yangyang Wang, Mingjun Gao, Anguo Wu, Longyi Chen, Jie Mei, Lulin Huang, Ruxiang Xu

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Clinical features and risk factors of HIV-infected patients with intracerebral hemorrhage: a retrospective study with propensity score matching analysis by Qiuhui Huang, Shengri Chen, Hua Huang, Xuhui Deng, Gengyu Cen, Miao Wang, Zhijian Liang

Subjects: “…intracerebral hemorrhage…”
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Investigation on extended care needs of patients with hypertensive intracerebral hemorrhage (高血压性脑出血患者延续性护理服务需求调查) by QIU Yajiao (邱亚娇), LIANG Hui (梁慧), WANG Fang (王芳)

Subjects: “…hypertensive intracerebral hemorrhage…”
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Human Placenta-Derived Mesenchymal Stem Cells Reduce Mortality and Hematoma Size in a Rat Intracerebral Hemorrhage Model in an Acute Phase by Bo Young Choi, Ok Joon Kim, Sae-Hong Min, Jeong Hyun Jeong, Sang Won Suh, Tae Nyoung Chung

“…Intracerebral hemorrhage (ICH) is a critical disease, highly associated with mortality and morbidity. …”
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Development and external validation of a dynamic nomogram for predicting the risk of functional outcome after 90 days in patients with acute intracerebral hemorrhage by Shaojie Li, Hongjian Li, Jiani Chen, Baofang Wu, Jiayin Wang, Chaocan Hong, Changhu Yan, Weizhi Qiu, Yasong Li, Hongzhi Gao

Subjects: “…intracerebral hemorrhage…”
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Minimally Invasive Parafascicular Surgery (MIPS) for Spontaneous Intracerebral Hemorrhage Compared to Medical Management: A Case Series Comparison for a Single Institution by Victoria L. Phillips, Anil K. Roy, Jonathan Ratcliff, Gustavo Pradilla

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Serum neuritin as a predictive biomarker of early neurological deterioration and poor prognosis after spontaneous intracerebral hemorrhage: a prospective cohort study by Yanwen Xu, Hanyu Zhu, Yuqi Su, Zhizhi Chen, Chuanliu Wang, Ming Yang, Feifei Jiang, Yunping Li, Yongming Xu

Subjects: “…intracerebral hemorrhage…”
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Machine learning-based pipeline for automated intracerebral hemorrhage and drain detection, quantification, and classification in non-enhanced CT images (NeuroDrAIn). by Samer Elsheikh, Ahmed Elbaz, Alexander Rau, Theo Demerath, Elias Kellner, Ralf Watzlawick, Urs Würtemberger, Horst Urbach, Marco Reisert

“…The objective is to develop and validate a fully automated pipeline for intracerebral hemorrhage and drain detection, quantification of intracerebral hemorrhage coverage, and detection of malpositioned drains.…”
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Protective effect of silencing lncRNA HCP5 against brain injury after intracerebral hemorrhage by targeting miR-195-5p by Zhanhua Lu, Kun Huang

“…Abstract Background Intracerebral hemorrhage (ICH) is a common subtype of stroke, characterized by a high mortality rate and a tendency to cause neurological damage. …”
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Andexanet alfa for oral fxa inhibitor-associated major acute intracerebral hemorrhage: insights into clinically relevant thromboembolic events from the ANNEXA-I study by Mateo Porres-Aguilar, Luis Antonio Meillon-Garcia, João Carlos de Campos Guerra

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Association of C-Reactive Protein with Short-Term Outcomes in Spontaneous Intracerebral Hemorrhage Patients with or without Infection: From a Large-Scale Nationwide Longitudinal Registry by Du Y, Liu L, Kang K, Lin Y, Gu H, Bian L, Li Z, Zhao X

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Predicting intracerebral hemorrhage after endovascular therapy for anterior circulation strokes using CT-ASPECT, CTP-ASPECT and DWI-ASPECT: Protocol for a systematic review. by Vincent Brissette, Chirayu Bhatt, Brian Dewar, Risa Shorr, Jordi Pardo, Robert Fahed, Michel Shamy, Dar Dowlatshahi

“…Despite the success of EVT on overall outcomes, intracerebral hemorrhage (ICH) is an important post-procedure complication, often associated with mortality and disability. …”
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Long-term efficacy and safety of endoscopic surgery versus small bone window craniotomy for spontaneous supratentorial intracerebral hemorrhage: a meta-analysis and trial sequential analysis by Chen Guo, Yang Bai, Xiaobin Zhang, Pinjing Zhang, Song Han, Di Fan

Subjects: “…Spontaneous supratentorial intracerebral hemorrhage…”
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