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461
Latent tuberculosis prevalence in healthcare workers in Laos: a cross-sectional study
Published 2025-01-01“…Healthcare workers are a group who have increased risk of infection and onward transmission to their patients and other susceptible individuals; however, LTBI is often undiagnosed, and individuals are asymptomatic. Interferon gamma release assays (IGRA) can detect evidence of TB infection in otherwise asymptomatic individuals and are a good indication of LTBI. …”
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462
Risk Factors for Latent Tuberculosis Infection (LTBI) Among Household Contacts of TB Patients: A Systematic Review
Published 2024-11-01“…Inclusion criteria included studies on LTBI risk factors among household contacts of TB patients, written in English or Indonesian, research articles, and participants who lived with an active TB patient for at least one night and/or had frequent interactions with the patient within three months prior to TB treatment, Interferon-Gamma Release Assays (IGRA) or Tuberculin Skin Test (TST) tests were required. …”
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463
Nutrition Therapy for Liver Diseases Based on the Status of Nutritional Intake
Published 2012-01-01“…The main treatment for chronic hepatitis C (CHC) is interferon-based antiviral therapy, which often causes a decrease in appetite and energy intake; hence, nutritional support is also required during therapy to prevent undernourishment, treatment interruption, and a reduction in quality of life. …”
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464
Indolent B-Cell Lymphomas Associated with HCV Infection: Clinical and Virological Features and Role of Antiviral Therapy
Published 2012-01-01“…Recently, antiviral treatment with interferon with or without ribavirin has been proved to be effective in the treatment of HCV-positive patients affected by indolent lymphoma, prevalently of marginal zone origin. …”
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465
Dose and strain dependent lethality of Usutu virus in an Ifnar−/− mouse model
Published 2025-01-01“…In this study we inoculated interferon α/β receptor knockout (Ifnar−/−) mice with decreasing doses of USUV, monitoring symptoms and survival to determine a less lethal dose, and we directly compared isolates from three different viral lineages. …”
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466
Salivary stimulatory and anti-inflammatory effects of aqueous Lilium brownii var. viridulum Baker extract for Sjögren’s syndrome: in vitro and in vivo studies
Published 2025-01-01“…In NOD/SCID mice, LB reduced anti-SSA/Ro and anti-SSB/La antibodies, tumor necrosis factor-α, interferon-γ, and interleukin-6, while increasing AQP-5 and M3R expression. …”
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467
Manganese-pyrochloric acid photosensitizer nanocomplexes against osteosarcoma: achieving both high activatability and high effectiveness
Published 2025-02-01“…Additionally, Mn2+ ions activated the cyclic GMP-AMP synthase (cGAS)-stimulator of interferon genes (STING) pathway, promoting maturation of dendritic cells (DCs) and augmenting CD8+-mediated antitumor immune responses.DiscussionThis study advances the on-demand activation of photosensitive drugs and photodynamic immunotherapy toward clinical applicability by exploiting Mn2+–PPa nanocomplexes with high activatability and effectiveness for targeted PDT and immunotherapy.…”
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468
Effects of Salmonella Typhimurium infection on intestinal flora and intestinal tissue arachidonic acid metabolism in Wenchang chickens
Published 2025-01-01“…The relative mRNA levels of inflammatory factors were also increased after infection, including Interferon-γ (IFN-γ), Transforming growth factor-β1 (TGF-β1), Interleukin-4 (IL-4), and Interleukin-6 (IL-6). …”
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469
Efficacy and safety of pharmacological treatments in inclusion body myositis: a systematic review
Published 2025-01-01“…Trials of methotrexate (MTX), intravenous immunoglobulin, interferon beta-1a and MTX, MTX and anti-T-lymphocyte immunoglobulin, oxandrolone, MTX and azathioprine, bimagrumab, arimoclomol, and sirolimus provided low-quality to high-quality evidence of having no effect on the progression of IBM.Conclusions Drug interventions for IBM were not effective for most of the outcomes of interest. …”
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470
Association of Interleukin-18 Gene Polymorphism with Susceptibility to Visceral Leishmaniasis in Endemic Area of Bihar, an Indian Population
Published 2014-01-01“…Interleukin-18 (IL-18) is a cytokine that mediates Th1 response by inducing interferon-gamma (IFN-γ) production in T cells and natural killer cells. …”
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471
Telaprevir in treatment of chronic hepatitis C: safety issues
Published 2012-07-01“…Investigations carried out to the present time demonstrated, that addition of telaprevir to standard therapy by pegilated interferon-alpha and ribavirin increases frequency of achievement sustained virologic response in CHC patients with the 1 genotype of virus almost 2-fold. …”
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472
Triptolide Inhibits Th17 Response by Upregulating microRNA-204-5p and Suppressing STAT3 Phosphorylation in Psoriasis
Published 2022-01-01“…Enzyme-linked immunosorbent assay was conducted to examine interleukin (IL)-17 and interferon-γ (IFN-γ) levels using corresponding kits. …”
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473
OK-432 Acts as Adjuvant to Modulate T Helper 2 Inflammatory Responses in a Murine Model of Asthma
Published 2018-01-01“…Herein, we demonstrate that OK-432 acts as an adjuvant to favor a systemic Th1 polarization with an elevation in interferon- (IFN-) γ and ovalbumin- (OVA-) immunoglobulin (Ig) G2a. …”
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474
On the pursuit of reproducibility: the importance of large sample sizes in psychoimmunology
Published 2025-01-01“…However, in typically-sized psychoimmunology studies (N < 200) that explore associations between PIMs and neurobiological/psychosocial constructs related to depression and studies that examine less-studied PIMs (e.g., interferon gamma), significant concerns about reproducibility of results exist. …”
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475
The Effect of Chronic Candesartan Therapy on the Metabolic Profile and Renal Tissue Cytokine Levels in the Obese Zucker Rat
Published 2010-01-01“…Moreover, renal IL-1α, -2, -4, -6 and -10 tumor necrosis factor-α, interferon-γ, were significantly reduced in OZ relative to LZ, and increased by candesartan. …”
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476
Role of Inflammasomes in Neuroimmune and Neurodegenerative Diseases: A Systematic Review
Published 2018-01-01“…Additionally, inflammasomes affect the efficacy of interferon-β therapy in patients with MS. Finally, the strong association of inflammasomes with AD and PD needs to be further studied. …”
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477
Gender-Specific Cytokine Pathways, Targets, and Biomarkers for the Switch from Health to Adenoma and Colorectal Cancer
Published 2011-01-01“…Our results show that the interferon (IFN)γ production pathway for immune response homeostasis is specific to men whilst the interleukin- (IL-) 6 production pathway for immune response homeostasis is specific to women. …”
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478
Promotion of beta cell proliferation through DYRK kinase inhibition using the marine natural product breitfussin C
Published 2025-01-01“…Abstract Pro-inflammatory cytokines, like interleukin-1 beta and interferon gamma, are known to activate signalling pathways causing pancreatic beta cell death and dysfunction, contributing to the onset of diabetes. …”
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479
MANDİBULADA GÖRÜLEN SANTRAL DEV HÜCRELİ GRANÜLOMUN SİSTEMİK KALSİTONİN UYGULAMASI İLE TEDAVİSİ: BİR OLGU SUNUMU
Published 2018-04-01“…Tedavisinde sıklıkla küretaj tercih edilmesinin yanında, son yıllarda intralezyonel steroid ve interferon- α (IFN-α) uygulaması, sistemik kalsitonin kullanılması gibi yöntemlerden de faydalanılmaktadır. …”
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480
Anti-Inflammatory and Neuroprotective Role of Natural Product Securinine in Activated Glial Cells: Implications for Parkinson’s Disease
Published 2017-01-01“…Additionally, securinine also inhibited interferon-γ- (IFN-γ-) induced nitric oxide levels and iNOS mRNA expression. …”
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