Implementation of Distributed Generation with Solar Plants in a 132 kV Grid Station at Layyah Using ETAP by Ghulam Mujtaba, Zeeshan Rashid, Farhana Umer, Shadi Khan Baloch, G. Amjad Hussain, Muhammad Usman Haider

“…Key features of renewable integration in a distribution network include loss minimization, voltage stability, power quality improvement, and low-cost consumption resulting from abundant natural resources such as solar or wind energy. …”
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TUBA1B as a novel prognostic biomarker correlated with immunosuppressive tumor microenvironment and immunotherapy response by Juntao Qi, Juntao Qi, Mingming Zhou, Na Yang, Huiyun Ma, Min He, Gujie Wu, Chang Ge, Liuyin Jin, Lin Cheng, Wei Liao, Hefei Ren, Caiyun Lei

“…Despite its fundamental roles, TUBA1B’s impact on tumor prognosis and the tumor immune microenvironment across cancer types remains inadequately understood.Methods To elucidate TUBA1B’s role in cancer prognosis and immune response, we conducted a comprehensive analysis, integrating data from established databases such as The Cancer Genome Atlas, Genotype Tissue Expression, Cancer Cell Lineage Encyclopedia, Human Protein Atlas, Kaplan-Meier Plotter, cBioPortal, TIMER, and ImmuCellAI, along with a large-scale clinical study and immunotherapy cohort. …”
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The accumulation of harmful genes within the ROH hotspot regions of the Tibetan sheep genome does not lead to genetic load by Lixia Sun, Chao Yuan, Tingting Guo, Yaqin Bai, Zengkui Lu, Jianbin Liu

“…These genes exhibited highly conserved within the ROH hotspot regions across all Tibetan sheep populations. Employing the integrated haplotype score (iHS) method, we screened for selective sites within frequently observed ROH hotspot regions to elucidate genomic differences among Tibetan sheep populations. …”
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Advancements in noninvasive techniques for transplant rejection: from biomarker detection to molecular imaging by Yuan Song, Yihui Wang, Wenyuan Wang, Yuji Xie, Junmin Zhang, Jing Liu, Qiaofeng Jin, Wenqian Wu, He Li, Jing Wang, Li Zhang, Yali Yang, Tang Gao, Mingxing Xie

“…Notably, dd-cfDNA and nuclear medicine imaging have already been integrated into clinical practice, thereby demonstrating the translational potential of these techniques. …”
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Gas-phase fractionation DDA promotes in-depth DIA phosphoproteome analysis by Zhiwei Tu, Yabin Li, Shuhui Ji, Shanshan Wang, Rui Zhou, Gertjan Kramer, Yu Cui, Fei Xie

“…The GPF-DDA data is integrated into the library-free DIA database search to create a hybrid library, enhancing phosphopeptide identification. …”
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Validation of a Questionnaire Assessing Pregnant Women’s Perspectives on Addressing the Psychological Challenges of Childbirth by Mihaela Corina Radu, Mihai Sebastian Armean, Razvan Daniel Chivu, Justin Aurelian, Melania Elena Pop-Tudose, Loredana Sabina Cornelia Manolescu

“…Understanding these variables is essential for providing appropriate counseling and psychosocial support, thereby optimizing the birth experience and promoting the health of both mother and child. The integration of multi-factor and single-factor models in the questionnaire analysis serves complementary purposes, providing distinct yet interrelated insights into the instrument’s structure and validity.…”
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It depends on how you tell: a qualitative diagnostic analysis of the implementation climate for community-wide mass drug administration for soil-transmitted helminth by Judd L Walson, Saravanakumar Puthupalayam Kaliappan, Sitara Swarna Rao Ajjampur, Sarah Lawrence, Khumbo Kalua, Euripide Avokpaho, Amy Roll, Angelin Titus, Yesudoss Jacob, Marie Claire Gwayi-Chore, Félicien Chabi, Comlanvi Innocent Togbevi, Abiguel Belou Elijan, Providence Nindi, Moudachirou Ibikounle, Kumudha Aruldas, Arianna Rubin Means

“…We used the Consolidated Framework for Implementation Research to guide the design of the interview guide and thematic analysis.Results Across all three sites, aspects of the implementation climate that were facilitators to cMDA launch included: high community member demand for cMDA, integration of cMDA into existing vaccination campaigns and/or health services, and engagement with familiar health workers. …”
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Leveraging machine learning for enhanced reservoir permeability estimation in geothermal hotspots: a case study of the Williston Basin by Abdul-Muaizz Koray, Emmanuel Gyimah, Mohamed Metwally, Hamid Rahnema, Olusegun Tomomewo

“…Our study showcases an integrated approach to predicting reservoir permeability, considering limited core data. …”
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Systematic review and meta-analysis on the prevalence and risk factors of oral frailty among older adults by Pingping Huang, Linjing Wu, Rongxiang Zhang, Rongxiang Zhang, Shiqi Chen, Shiqi Chen, Yu Zhang, Yuan Chen, Yuan Chen

“…ObjectivesThe present study aim to systematically review the prevalence and influencing factors of oral frailty in older people.MethodsA search strategy was developed and implemented to systematically review literature across PubMed, Embase, Web of Science, MEDLINE (via EBSCOhost), CINAHL, the Cochrane Library, Scopus, China Knowledge Resource Integrated Database (CNKI), Wanfang Data, Chinese Biomedical Database (CBM), and Weipu Database (VIP), in accordance with the PRISMA 2020 guidelines. …”
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Energy-innovation knowledge common connection point management in preventing outbreak of the Covid-19 pandemic in a University by V. Shcherbak, I. Gryshchenko, L. Ganushchak-Yefimenko, O. Nifatova, V. Bobrovnyk, M. Verhun

“…The cluster analysis was used to perform energy certification of university offices according to the indicators of integral energy efficiency potential and the level of annual specific energy consumption. …”
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Research priorities for autosomal dominant polycystic kidney disease: a UK priority setting partnership by Tess Harris, Albert Ong, Paul J D Winyard, Richard N Sandford, Maryrose Tarpey, Hannah R Bridges, Wendy D Brown, Natasha L O’Brien, Ann C Daly, Bharat K Jindal, Gillian S Mundy, Albert J Power, John Sayer, Roslyn J Simms, Patricia D Wilson

“…The Polycystic Kidney Disease Charity began a priority setting partnership with the James Lind Alliance (JLA) in the UK in 2019–2020 to identify areas of uncertainty in the ADPKD care pathway and allow patients, carers and healthcare professionals to rank the 10 most important questions for research.Design The scope covered ADPKD diagnosis and management, identifying new treatments to prevent/slow disease progression and practical, integrated patient support (https://pkdcharity.org.uk/research/for-researchers/adpkd-research-priorities). …”
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Spatiotemporal optimization of irrigation practices for winter wheat in China: Rationale, implications, and solutions by Luchen Zhang, Yuan Cao, Weihao Qian, Junning Tian, Shengshi Huang, Xiaolei Qiu, Bing Liu, Liang Tang, Liujun Xiao, Weixing Cao, Yan Zhu, Leilei Liu

“…Subsequently, a multi-model ensemble approach integrated with a multi-objective optimization algorithm was utilized to propose the optimized irrigation strategies, which could enhance water use efficiency while attaining high yields. …”
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Adjustment of the Framingham index by abdominal aortic calcification scores enables a more accurate prediction of long-term cardiac events in general population aged 40 years and a... by Xiao-Jun Liu, Li Wang, Li-sha Zhang, Li-Fei Cao, Zhao-Fei Wan, Jia-Hong Xue, Yan-Ru He, Xin-Hong Wang, Xiao-Fang Bai

“…Additionally, the predictive value of FRS alone and combined with AAC score was estimated by comparing the area under the receiver-operating characteristic (ROC) curve (AUC) and calculating Integrated Discrimination Improvement (IDI). Results During a median of 70.50 months (interquartile range 58.43–82.57 months), 49 (1.649%) experienced cardiac death in the follow-up. …”
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Creation of a recombinant Komagataella phaffii strain, a producer of proteinase K from Tritirachium album by A. B. Beklemishev, M. B. Pykhtina, Ya. M. Kulikov, T. N. Goryachkovskaya, D. V. Bochkov, S. V. Sergeeva, A. R. Vasileva, V. P. Romanov, D. S. Novikova, S. E. Peltek

“…The objects of the study were recombinant clones of Komagataella phaffii K51 carrying the heterologous proteinase K (PK-w) gene from Tritirachium album integrated into their genome as well as samples of recombinant proteinase K isolated from these clones. …”
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Deep learning–assisted diagnosis of acute mesenteric ischemia based on CT angiography images by Lei Song, Xuesong Zhang, Jian Zhang, Jie Wu, Jinkai Wang, Feng Wang

“…A Fusion Model was constructed by integrating clinical factors into the DL model. The performance of the models was assessed using receiver operating characteristic (ROC) curves and decision curve analysis (DCA).ResultsAlbumin and International Normalized Ratio (INR) were associated with AMI by univariate and multivariate logistic regression (P < 0.05). …”
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The INFLUENCE 3.0 model: Updated predictions of locoregional recurrence and contralateral breast cancer, now also suitable for patients treated with neoadjuvant systemic therapy by M.C. Van Maaren, T.A. Hueting, D.J.P. van Uden, M. van Hezewijk, L. de Munck, M.A.M. Mureau, P.A. Seegers, Q.J.M. Voorham, M.K. Schmidt, G.S. Sonke, C.G.M. Groothuis-Oudshoorn, S. Siesling

“…For NST patients this was similar, but excluding (y)pT and (y)pN status, and including presence of ductal carcinoma in situ, axillary lymph node dissection and pathologic complete response.For non-NST patients, the Cox and RSF models were integrated in the online tool with 5-year AUCs of 0.77 (95%CI:0.77–0.77) and 0.68 (95%CI:0.67–0.68)] for LRR and CBC prediction, respectively. …”
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Unveiling the ultimate advantage: a meta-analysis of 3D visualization and problem-based learning in orthopedic education by Ting Li, Yidan Hu, Ruohong Song, Hangyu Liu, Xin Gao, Fei Wang, Chengwei Xiao, Xilin Liu

“…However, there is a conspicuous lack of systematic reviews that thoroughly evaluate both the advantages and drawbacks of integrating 3D with problem-based learning (3D + PBL). …”
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Multispectral Inversion of Starch Content in Rice Grains from Yingjiang County Based on Feature Band Selection Algorithms by Xiaotong Su, Zhifang Zhao, Min Zeng, Fei Zhao, Ziyang Li, Yu Zheng

“…BP neural networks and ELM neural network regression models were then integrated to quantitatively estimate starch content across the study area. …”
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Nomograms for predicting recurrence of HER2‐positive breast cancer with different HR status based on ultrasound and clinicopathological characteristics by Xudong Zhang, Hanqing Kong, Xiaoxue Liu, Qingxiang Li, Xinran Fang, Junjia Wang, Zihao Qin, Nana Hu, Jiawei Tian, Hao Cui, Lei Zhang

“…Conclusions Ultrasound performance of HER2+ breast cancers with different HR status was significantly different. Nomograms integrating ultrasound and clinicopathological characteristics exhibited favorable performance and have the potential to serve as a reliable method for predicting recurrence in heterogeneous breast cancer.…”
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Spatiotemporal variability of groundwater chemistry, source identification and health risks in the southern Chinese Loess Plateau by Zijun Li, Qingchun Yang, Chuan Xie, Hongyun Ma, Bin Wu, Yanli Wang

“…The results showed that except for bicarbonate, spatiotemporal variability of hydrochemical components in Malian River Basin (ML) was generally greater than that in Upper Jinghe River basin (JH-U) due to the hydrogeological conditions, and the hydrochemical facies in two river basins transformed from SO4·Cl and Cl·SO4 types to HCO3 and HCO3·SO4 types. The results of integrated-weight quality index (IWQI) showed that 77.8 % (1970s), 33.3 % (2004), 34.3 % (2015) of samples in ML exceeded the standard limits of Class IV groundwater quality, displaying a high pollution level with an improvement trend, while groundwater quality in JH-U indicated a very low pollution level with a deterioration trend. …”
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