Impact of predictive selection of LbCas12a CRISPR RNAs upon on‐ and off‐target editing rates in soybean by Linda Rymarquis, Chenxi Wu, Diane Hohorst, Miguel Vega‐Sanchez, Thomas E. Mullen, Vijetha Vemulapalli, Douglas R. Smith

“…In addition, edits at off‐target sites have lower inheritance rates than on‐target edits, suggesting that they occur later in the plant's lifecycle. …”
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Clinical Epidemiological Look at Patients with Congenital Heart Disease: a Study that has Become a Priority by Jan O´neil González Ramos, Nancy González Vales, Eida María Mena Albernal, Elsy Roxana Geroy Moya, Nicolás Ramón Cruz Pérez, Annia Quintana Marrero

“…The maternal risk factor with the highest incidence was arterial hypertension, the most frequent inheritance and presentation was the murmur. Surgery was the predominant form of resolution, genetic diseases were the most frequent fetal risks. …”
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Influence of human settlements factors on the spatial distribution patterns of traditional villages in Liaoning province by Guiqiao Tao, Xueming Li, Shenzhen Tian, Hang Li, Yishan Song

“…Abstract Traditional villages embody China’s long-standing farming culture and are the carriers for the inheritance and development of traditional culture in rural China. …”
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Monoallelic variants resulting in substitutions of MAB21L1 Arg51 Cause Aniridia and microphthalmia. by Hildegard Nikki Hall, Hemant Bengani, Robert B Hufnagel, Giuseppe Damante, Morad Ansari, Joseph A Marsh, Graeme R Grimes, Alex von Kriegsheim, David Moore, Lisa McKie, Jamalia Rahmat, Catia Mio, Moira Blyth, Wee Teik Keng, Lily Islam, Meriel McEntargart, Marcel M Mannens, Veronica Van Heyningen, Joe Rainger, Brian P Brooks, David R FitzPatrick

“…These mutations occurred de novo in 3/5 families, with the remaining families being compatible with autosomal dominant inheritance. Mice engineered to carry the p.Arg51Leu change showed a highly-penetrant optic disc anomaly in heterozygous animals with severe microphthalmia in homozygotes. …”
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Phytoalexin deficient 4 is associated with the lesion mimic trait in watermelon clalm mutant (Citrullus lanatus) by Jiale Shi, Congji Yang, Yuanyuan Qin, Qingqing Liu, Shengqi Hua, Defeng Wu, Wei Dong

“…In this study, we tested a seven-generation family to determine the inheritance and genetic basis of this trait. As revealed by analysis of the lesion mimic mutant clalm, this trait is controlled by a single dominant gene. …”
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Assessment of Genetic Parameters for Vitamin A, Vitamin C, and TSS Content Results in Melon Line Crosses at Five Maturity Stages by Achmad Amzeri, Kaswan Badami, Amin Zuhri, Gita Pawana, Suhartono Suhartono, Syaiful Khoiri, Ahmad Syaiful Umam, Yudi Asmoro, Siti Rohmatin, Halimatus Sa’diyah, Badriyah Badriyah

“…The right harvest time for the eight genotypes tested was maturity stage 4 (70 DAP) because it had the highest vitamin A, vitamin C, and TSS contents compared to other maturity stages. The inheritance of vitamin A and C content was not affected by the maternal effect, while TSS was influenced by the maternal effect. …”
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Radiation-induced impacts on mitochondrial DNA and the transgenerational genomic instability by Ryosuke Seino, Haruka Kubo, Kai Nishikubo, Hisanori Fukunaga

“…In this study, we investigated the radiation-induced impacts on mitochondrial DNA in vitro and in vivo, as well as the transgenerational inheritance. Methods: Human cervical cancer HeLa cells and telomerase-immortalized normal fibroblast BJ1-hTERT cells were exposed to X-rays at 0.5–8 Gy. …”
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Devonian–Mississippian magmatism related to extensional collapse in Svalbard: implications for radiating dyke swarms [version 1; peer review: 2 approved] by Gillian R. Foulger, Sebastian Tappe, Jean-Baptiste P. Koehl, Ingrid M. Anell

“…Thus, the radiating emplacement pattern of the magmatic intrusions of the Kola–Dnieper Large Igneous Province are not the product of plume-related uplift but of structural inheritance. A similar line of reasoning is successfully applied to intrusions of the Yakutsk–Vilyui and High Arctic large igneous provinces.…”
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Effect of Social Environment on The Effectiveness of HIV/AIDS Prevention: A Case Study of Rwamucucu Sub-County Rukiga District. by Nahiwera, Edverse

“…Other respondents mentioned violence in families, accessibility of health care services, and alcohol consumption, and the study findings on challenges to effective HIV/AIDS prevention, the highest number of respondents mentioned lack of coverage and access to prevention services. the lowest number of respondents mentioned a lack of accurate evaluations, other respondents mentioned stigma among rural communities, cost of treatment, and lack of awareness and the study results on HIV/AIDS prevention measures, the highest number of respondents mentioned social marketing of condoms, the lowest number of respondents mentioned encouraging being faithful to their partners. other respondents mentioned having school-based HIV prevention programs, discouraging wife inheritance, and voluntary counseling and testing of the people. …”
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High-Density Genetic Map Construction and QTL Detection for Cotyledon Color in Faba Bean Based on Double Digest Restriction-Site Associated DNA Sequencing (ddRAD-Seq) by Changcai Teng, Hongyan Zhang, Wanwei Hou, Ping Li, Xianli Zhou, Yujiao Liu

“…F₁-, F₂-, BC₁F₁-, and BC₂F₁-generation single-plant cotyledon colors were counted to clarify cotyledon color inheritance. F₂-generation individuals were genotyped using ddRAD-Seq to construct a genetic linkage map and identify QTLs for cotyledon color. …”
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Introgressions of Vitis rotundifolia Michx. to obtain grapevine genotypes with complex resistance to biotic and abiotic stresses by V. A. Volynkin, V. V. Likhovskoi, I. A. Vasylyk, N. A. Rybachenko, E. A. Lushchay, S. M. Gorislavets, V. A. Volodin, V. I. Risovannaya, E. K. Potokina

“…The present study reports new scientific knowledge about the inheritance of resistance to downy mildew, powdery mildew and frost by V. vinifera varieties from V. rotundifolia. …”
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The Utah Population Database. A Model for Linking Medical and Genealogical Records for Population Health Research by Ken R. Smith, Alison Fraser, Diana Lane Reed, Jahn Barlow, Heidi A. Hanson, Jennifer West, Stacey Knight, Navina Forsythe, Geraldine P. Mineau

“…Genetic researchers have used UPDB to identify and study individuals and families that have higher than normal incidence of diseases or other traits, to analyze patterns of genetic inheritance, and to identify specific genetic mutations. …”
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Efficiency of using SNP markers in the <i>MSTN</i> gene in the selection of the Pushkin breed chickens by N. V. Dementeva, A. B. Vakhrameev, T. A. Larkina, O. V. Mitrofanova

“…Traditional selection based on phenotypic evaluation is characterized by low efficiency with a low character inheritance ratio and is difficult to apply in small groups of animals and birds bred in bioresource collections. …”
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Exploring diazotrophic diversity: unveiling Nif core distribution and evolutionary patterns in nitrogen-fixing organisms by Bruno Thiago de Lima Nichio, Roxana Beatriz Ribeiro Chaves, Fábio de Oliveira Pedrosa, Roberto Tadeu Raittz

“…This study aimed to identify potential diazotroph groups based on the Nif core and to analyze the inheritance patterns of accessory Nif proteins related to Mo-nitrogenase, along with their impact on N2 fixation maintenance. …”
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Diallel Analysis and Heritability of Grain Yield, Yield Components, and Maturity Traits in Cowpea (Vigna unguiculata (L.) Walp.) by Emmanuel Yaw Owusu, Haruna Mohammed, Kulai Amadu Manigben, Joseph Adjebeng-Danquah, Francis Kusi, Benjamin Karikari, Emmanuel Kofi Sie

“…The findings from this study provide useful information on the inheritance of early maturity and yield traits in cowpea. …”
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Verification of the Introgression of <i>Narenga porphyrocoma</i> Germplasm into <i>Saccharum officinarum</i> Using Molecular Markers and GISH Analysis by Gang Wang, Wei Zhang, Yuanxia Qin, Qingdan Wu, Qinggan Liang, Jiantao Wu, Shengren Sun, Zhuqing Wang, Yuxing An, Jianqiang Wang, Qinnan Wang, Hailong Chang

“…Species-specific primers were designed based on SNPs in the nrDNA-ITS region for ARMS-PCR, enabling effective differentiation of parental and hybrid genotypes, while GISH confirmed the chromosomal composition of hybrids, revealing an n + n inheritance pattern. The results demonstrated the potential of <i>N. porphyrocoma</i> to improve sugarcane’s tillering and leaf length, although sucrose content was lower in hybrids, suggesting the need for further breeding efforts. …”
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Genetic markers of children asthma: predisposition to disease course variants by M. V. Smolnikova, Ed. W. Kasparov, M. A. Malinchik, K. V. Kopylova

“…Asthma is a multifactorial disease with a significant genetic determinant, however, the inheritance of asthma has not been fully elucidated. …”
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Manifestation of agronomically valuable traits in the progeny of a sorghum mutant carrying the genetic construct for RNA silencing of the γ-kafirin gene by L. A. Elkonin, N. V. Borisenko, T. E. Pylaev, O. A. Kenzhegulov, S. Kh. Sarsenova, N. Yu. Selivanov, V. M. Panin

“…The goal of this work was to study the stability of inheritance of the introduced genetic construct in T2–T4 generations, to identify the number of its copies, as well as to trace the manifestation of agronomically valuable traits in the offspring of the mutant. …”
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The values of Hellenic culture as the foundation of Nietzsche's philosophy by Stanković-Pejnović Vesna, Veseli Damir

“…Nietzsche does not reject not the tradition or modernity's inheritance of it. In Nietzsche's reading, Greek culture, like all flourishing types, understood the need for meaning, purpose, direction and goals, and responded to this need by 'toppling boundary stones', but also by constructing 'new religions and moralities'. …”
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Association of TCF7L2 genetic variants rs12255372 and rs7903146 with the polycystic ovary syndrome risk: systematic review and meta-analysis by Idrees A. Shah, Rabiya Rashid, Haroon Rashid, Abid Bhat, Mohd Ashraf Ganie

“…Similarly, the genetic variant rs12255372 was not associated with PCOS risk both in the allelic and the dominant inheritance model(p > 0.05). Unlike East Asians (MAF < 0.025), both variants are highly frequent across other global populations including America, South Asia, and Europe (MAF ≥ 0.19). …”
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