The role of autophagy in Graves disease: knowns and unknowns by Hayder M. Al-kuraishy, Ghassan M. Sulaiman, Hamdoon A. Mohammed, Mohammed H. Abu-Alghayth, Salim Albukhaty, Majid S. Jabir, Ali K. Albuhadily, Ali I. Al-Gareeb, Daniel J. Klionsky, Mosleh M. Abomughaid

“…Autophagy plays a critical role in many thyroid diseases and in different stages of the same disease through modulation of immunity and the inflammatory response. In addition, autophagy is also implicated in the pathogenesis of thyroid-associated ophthalmopathy (TAO). …”
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Bacterial aetiology of chronic otitis media with effusion in children - risk factors by Izabela Korona-Glowniak, Agata Wisniewska, Marek Juda, Karolina Kielbik, Grazyna Niedzielska, Anna Malm

“…Abstract Background Otitis media with effusion (OME) may occur spontaneously because of poor Eustachian tube function or as an inflammatory response following AOM. Bacterial involvement in OME has been widely reported, with various available methods to identify pathogens from middle ear effusion, including traditional culture methods and polymerase chain reaction (PCR). …”
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Genetics of aging and longevity by A. A. Moskalev, E. N. Proshkina, A. A. Belyi, I. A. Solovyev

“…Genes and signaling pathways that regulate stress response, metabolism, growth of cells and organism, maintaining of genome and proteome integrity, qualitative and quantitative mitochondria composition, inflammatory response, apoptosis and selection of viable cells, as well as circadian rhythms were considered. …”
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Gut Microbial Translocation in Critically Ill Children and Effects of Supplementation with Pre- and Pro Biotics by Paola Papoff, Giancarlo Ceccarelli, Gabriella d'Ettorre, Carla Cerasaro, Elena Caresta, Fabio Midulla, Corrado Moretti

“…Bacterial translocation as a direct cause of sepsis is an attractive hypothesis that presupposes that in specific situations bacteria cross the intestinal barrier, enter the systemic circulation, and cause a systemic inflammatory response syndrome. Critically ill children are at increased risk for bacterial translocation, particularly in the early postnatal age. …”
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Epithelial-to-Mesenchymal Transition in Pancreatic Ductal Adenocarcinoma and Pancreatic Tumor Cell Lines: The Role of Neutrophils and Neutrophil-Derived Elastase by Thomas Große-Steffen, Thomas Giese, Nathalia Giese, Thomas Longerich, Peter Schirmacher, G. Maria Hänsch, Matthias M. Gaida

“…Because in pancreatic cancers the transition to a mesenchymal phenotype coincides with the PMN infiltrate, a contribution of the inflammatory response to the induction of EMT and—by implication—to tumor progression is possible.…”
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The oral microbiota: new insight into intracranial aneurysms by Wentao Gong, Hairong Yu, Wei You, Zhen Chen, Yu Wang, Chao Liu, Youxiang Li, Sheng Guan

“…The review explores how these pathogens may mediate chronic inflammation through hematogenous spread, gut microbiome alterations, and neuroinflammatory processes, leading to vascular remodeling and cerebrovascular instability.Results The findings suggest that oral microbial dysbiosis, particularly the presence of pathogenic bacteria, is implicated in the systemic inflammatory response that exacerbates the structural integrity of the cerebrovascular wall. …”
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AIM2 Mediates Inflammation-Associated Renal Damage in Hepatitis B Virus-Associated Glomerulonephritis by Regulating Caspase-1, IL-1β, and IL-18 by Junhui Zhen, Le Zhang, Jiachao Pan, Shumin Ma, Xiaojian Yu, Xiaobo Li, Shijun Chen, Wenjun Du

“…We therefore analyzed the expression of AIM2 and inflammatory factors in HBV-GN tissues and cell lines relative to the inflammatory response to HBV infection and HBV status. Methods. …”
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Peroxisome Proliferator-Activated Receptor γ Induces the Expression of Tissue Factor Pathway Inhibitor-1 (TFPI-1) in Human Macrophages by G. Chinetti-Gbaguidi, C. Copin, B. Derudas, N. Marx, J. Eechkoute, B. Staels

“…As a functional consequence, treatment with PPARγ ligands significantly reduces the inflammatory response induced by FVIIa, as measured by variations in the IL-8, MMP-2, and MCP-1 expression. …”
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Exploring single cell microbial protein as a sustainable fishmeal alternative in yellowtail kingfish (Seriola lalandi) diets: impacts on health and gut microbiome by Luke Pilmer, Lindsey Woolley, Alan Lymbery, Chinh Dam, Abigail Elizur, Md Javed Foysal, Gavin Partridge

“…Results The study found that SCP inclusion at the highest level of fishmeal replacement (75%) induced a mild inflammatory response in the hindgut of the fish. However, micromorphological assessments of the hindgut, serum biochemistry, and gene expression analyses revealed no significant detrimental effects from SCP replacement. …”
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Suppressive Effects of GSS on Lipopolysaccharide-Induced Endothelial Cell Injury and ALI via TNF-α and IL-6 by Lei Yi, Zengding Zhou, Yijuan Zheng, Mengling Chang, Xiaoqin Huang, Feng Guo, Quanming Zhao, Jingning Huan

“…Taken together, our results demonstrated that GSS might be a promising candidate for sepsis-induced ALI via its regulating effects on inflammatory response in lung ECs.…”
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Constructing a machine learning model for systemic infection after kidney stone surgery based on CT values by Jiaxin Li, Yao Du, Gaoming Huang, Yawei Huang, Xiaoqing Xi, Zhenfeng Ye

“…Abstract This study aims to develop a machine learning model utilizing Computed Tomography (CT) values to predict systemic inflammatory response syndrome (SIRS) after endoscopic surgery for kidney stones. …”
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Cathepsin G, a Neutrophil Protease, Induces Compact Cell-Cell Adhesion in MCF-7 Human Breast Cancer Cells by Tomoya Kudo, Hideaki Kigoshi, Takashi Hagiwara, Takahisa Takino, Masatoshi Yamazaki, Satoru Yui

“…Cathepsin G is a serine protease secreted by activated neutrophils that play a role in the inflammatory response. Because neutrophils are known to be invading leukocytes in various tumors, their products may influence the characteristics of tumor cells such as the growth state, motility, and the adhesiveness between cells or the extracellular matrix. …”
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Analysis of the effects of group progressive resistance training on inflammatory markers, cardiovascular fitness parameters, and respiratory function in elderly patients with chron... by Chunyang Li, Yijia Sun

“…Conclusions: Group progressive resistance training can help improve the compliance of elderly patients with chronic obstructive pulmonary disease with training, reduce the body's inflammatory response, improve VO2MAX, VEmax, O2pulsemax, and HRmax levels, and alleviate breathing difficulties.…”
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MicroRNA-29b Suppresses Inflammation and Protects Blood-Brain Barrier Integrity in Ischemic Stroke by Xiaoqing Ma, Ho Jun Yun, Kenneth Elkin, Yunliang Guo, Yuchuan Ding, Guangwen Li

“…Leukocytic miR-29b attenuates inflammatory response by augmenting BBB integrity through C1QTNF6, suggesting a novel miR-29b-based therapeutic therapy for ischemic stroke.…”
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Application and effect mechanism of electrical nerve stimulation modulation technology in rehabilitation therapy following spinal cord injury by LIU Wenhui, SUN Wenting, HU Naichong, LI Yanpi, ZHAO Jingjun

“…The mechanism of action of the electrical nerve stimulation modulation technique for SCI may be related to modulating neural excitability，thus promoting the reconstruction of neural circuits and facilitating the cascade inflammatory response. Additionally，the technique has been observed to modulate synaptic plasticity，which may contribute to the regeneration and repair of nerve tissue. …”
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The Role of IL-17 Promotes Spinal Cord Neuroinflammation via Activation of the Transcription Factor STAT3 after Spinal Cord Injury in the Rat by Shaohui Zong, Gaofeng Zeng, Ye Fang, Jinzhen Peng, Yong Tao, Keke Li, Jingmin Zhao

“…The purpose of the experiments is to study the expression of IL-17 and related cytokines via STAT3 signaling pathways, which is caused by the acute inflammatory response following SCI in different periods via establishing an acute SCI model in rat. …”
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Interleukin-34 as a Robust Predictor of No-Reflow Phenomenon in ST-Elevation Myocardial Infarction: Insights into Inflammatory Mechanisms and Clinical Implications by Mehdi Karasu, Hasan Ata Bolayır, İbrahim Aktaş

“…Conclusion: IL-34 emerges as a robust predictor of no-reflow in STEMI, potentially reflecting its role in macrophage activation and the inflammatory response. These findings suggest a novel avenue for understanding and mitigating no-reflow in STEMI, paving the way for targeted therapies. …”
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Exploring the protective role of caffeine against Taraxacum-Induced ribotoxic stress mediated through autophagy and mitochondrial depolarization by Chien-Jung Lin, Shu-Ting Liu, Zih-Syuan Wu, Shih-Ming Huang, Teng-Wei Chen

“…Our RNA sequencing data showed that Taraxacum formosanum (T. formosanum) upregulated 893 genes and downregulated 509 genes and triggered hallmark genes of spliceosomes, TNF-α signaling via NF-κB, inflammatory response, and IL6-JAK-STAT3 signaling. Additionally, T. formosanum imbalanced the levels of ribosomal proteins of the large and small subunits. …”
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Single-cell transcriptome analysis reveals cellular reprogramming and changes of immune cell subsets following tetramethylpyrazine treatment in LPS-induced acute lung injury by Mingyan Wu, Shanmei Wang, Xiaolan Chen, Li Shen, Jurong Ding, Hongbin Jiang

“…Immunohistochemistry and enzyme-linked immunosorbent assay were performed to identify the effects of TMP on immune inflammatory response. Results We found that TMP efficiently protected against LPS-induced acute lung injury. …”
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Regulatory Role of GSK-3β on NF-κB, Nitric Oxide, and TNF-α in Group A Streptococcal Infection by Yu-Tzu Chang, Chia-Ling Chen, Chiou-Feng Lin, Shiou-Ling Lu, Miao-Huei Cheng, Chih-Feng Kuo, Yee-Shin Lin

“…Glycogen synthase kinase-3β (GSK-3β) is known to regulate inflammatory response in infectious diseases. However, the regulation of GSK-3β in GAS infection is still unknown. …”
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