Role of Astrocytic Dysfunction in the Pathogenesis of Parkinson’s Disease Animal Models from a Molecular Signaling Perspective by Lucas Udovin, Cecilia Quarracino, María I. Herrera, Francisco Capani, Matilde Otero-Losada, Santiago Perez-Lloret

“…Activation of astrocyte TRPV1 receptors by noxious stimuli results in reduced inflammatory response and increased ciliary neurotrophic factor (CNTF) synthesis, which enhances neuronal survival and differentiation. …”
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IL-33 Deficiency Attenuates Lung Inflammation by Inducing Th17 Response and Impacting the Th17/Treg Balance in LPS-Induced ARDS Mice via Dendritic Cells by Li Cheng, Yang Jiao, Wei Jiang, Xin Zhang, Liping Zhang, Gongwei Jia

“…The characteristic pathophysiological feature of acute respiratory distress syndrome (ARDS) is a dysregulated inflammatory response. T helper 17 (Th17) cells in the lung are inflammatory cells that contribute to pulmonary inflammatory cascades. …”
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Lipid mediators in post-mortem brain samples from patients with Alzheimer's disease: A systematic review by Aidan D. Tyrrell, Giulia Cisbani, Mackenzie E. Smith, Chuck T. Chen, Yue-Tong Chen, Raphael Chouinard-Watkins, Kathryn E. Hopperton, Ameer Y. Taha, Richard P. Bazinet

“…Dysregulation of lipid mediators derived from polyunsaturated fatty acids may contribute to this inflammatory response in the brain of patients with AD, yet the literature has not yet been systematically reviewed. …”
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Infectious Keratitis: Secreted Bacterial Proteins That Mediate Corneal Damage by Mary E. Marquart, Richard J. O'Callaghan

“…Most, but not all, of these proteins are secreted toxins and enzymes that mediate host cell death, degradation of stromal collagen, cleavage of host cell surface molecules, or induction of a damaging inflammatory response. Studies of these bacterial pathogens have determined the proteins of interest that could be targets for future therapeutic options for decreasing corneal damage.…”
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Update for diagnosis and treatment of syndrome after cardiac injury: a mini-review by Ruihui Lai, Tan Xu, Tan Xu

“…This condition is considered to be an autoimmune-mediated inflammatory response leading to pericarditis as the primary manifestation of the cardiac disease. …”
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Severe Eosinophilic Meningoencephalitis Secondary to Suspected Neuroangiostrongyliasis with a Good Clinical Outcome by Fabian Chiong, Andrew R. Lloyd, Jeffrey J. Post

“…Management of neuroangiostrongyliasis with anthelminthic is controversial as it is thought to cause worsened outcomes through inciting an inflammatory response as a result of parasite killing. We managed to successfully treat our patient using albendazole and prednisolone and achieved a good outcome.…”
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The Role of Leukotriene Receptor Signaling in Inflammation and Cancer by Ramin Massoumi, Anita Sjölander

“…The release of these mediators, by cells recruited to or present at the site of inflammation, modulate/influence the magnitude of the inflammatory response. A better understanding of eicosanoids and how their receptors trigger intracellular signaling during inflammatory conditions is helping to elucidate the well-known connection between chronic inflammatory disease and neoplastic transformation. …”
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Diagnostic and Prognostic Role of Procalcitonin in Infections by Maria Hatzistilianou

“…The problems with sepsis definitions and diagnoses are indications of the need to focus on biochemical mediators capable not only of distinguishing the inflammatory response to infection from other types of inflammation, but also of indicating the severity and prognosis of the disease. …”
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Relationship between Periodontitis and Ischemic Cerebrovascular Disease by Magda Pinilla Pérez, Elisa DBeche Riambau, Miriam Castro Ortega

“…Periodontitis is an immunoinflammatory disorder of microbial etiology caused by unique germs in the oral cavity that can spread through the bloodstream, activate the host's inflammatory response and promote the formation, maturation and exacerbation of atheromatous plaque. …”
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Correlation between the Neutrophil-to-Lymphocyte Ratio and Multiple Sclerosis: Recent Understanding and Potential Application Perspectives by Qingqing Zhou, Rui Jia, Jingxia Dang

“…In this review, we aimed to discuss the inflammatory response in MS, mainly the function of lymphocytes and neutrophils, which can be implemented in the utility of NLR as a diagnostic tool in MS patients. …”
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Imaging Molecular Expression on Vascular Endothelial Cells by In Vivo Immunofluorescence Microscopy by Judith M. Runnels, Parisa Zamiri, Joel A. Spencer, Isreal Veilleux, Xunbin Wei, Alexei Bogdanov, Charles P. Lin

“…Live imaging is particularly useful for following the dynamic expression of inducible molecules such as E-selectin during an inflammatory response.…”
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Dietary Glycaemic Index and Type 2 Diabetes Mellitus: Potential Modulation of Gut Microbiota by Hanusha Durganaudu, Thubasni Kunasegaran, Amutha Ramadas

“…Generally, diet has strong influence on the gut microbiota, which recently have been found to be associated with insulin resistance and the inflammatory response in diabetes. The possible modulation of the gut microbiota with dietary intervention is a topic of emerging interest, with limited evidence among T2DM population. …”
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Conservative Management of an Iatrogenic Esophageal Tear in Kenya by Peter Waweru, David Mwaniki

“…This rare, devastating, mostly iatrogenic, condition can quickly lead to severe complications and death due to an overwhelming inflammatory response to gastric contents in the mediastinum. …”
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Yersiniosis and acute secondary axonal sensorimotor polyneuropathy: a case report by A. Daškevičiūtė, R. Mameniškienė

“…This article presents a case of yersiniosis which presented with febrile fever and severe inflammatory response. At the onset of the disease, Guillain–Barre syndrome was suspected but later acute axonal sensorimotor polyneuropathy was diagnosed. …”
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Serum IL-1β, sIL-2R, IL-6, IL-8 and TNF-α in schizophrenic patients, relation with symptomatology and responsiveness to risperidone treatment by Ayşe Binnur Erbağci, Hasan Herken, Oya Köylüoglu, Necat Yilmaz, Mehmet Tarakçioglu

“…Activation of the inflammatory response system and varied levels of cytokines in acute schizophrenia have been suggested by recent studies. …”
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Multiple sclerosis: overview of orally administrated disease-modifying drugs. Do genetics influence the success of treatment? by A. Ovčinikova, R. Kizlaitienė

“…In MS treatment, disease modifying therapies (DMTs) are essential to reduce disease progression by suppressing the inflammatory response responsible for promoting lesion formation. …”
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Release of Inflammatory Mediators by Human Adipose Tissue Is Enhanced in Obesity and Primarily by the Nonfat Cells: A Review by John N. Fain

“…This paper considers the role of putative adipokines that might be involved in the enhanced inflammatory response of human adipose tissue seen in obesity. …”
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Selenium-Dependent Regulation of Oxidative Stress and Immunity in Periparturient Dairy Cattle by Lorraine M. Sordillo

“…Uncontrolled or impaired immune and inflammatory responses in periparturient dairy cows are associated with increased incidence and severity of infectious diseases. …”
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Invariant Natural Killer T Cells as Key Players in Host Resistance against Paracoccidioides brasiliensis by Joes Nogueira-Neto, Flavio V. Loures, Alessandra S. Schanoski, David A. G. Andrade, Michelangelo B. Gonzatti, Tania A. Costa, Bruno C. Vivanco, Patrícia Xander, Daniela S. Rosa, Vera L. G. Calich, Alexandre C. Keller

“…Although the mechanisms responsible for this phenomenon remain to be clarified, α-GalCer treatment boosted the local inflammatory response and reduced pulmonary fungal burden. …”
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Mesenchymal Stem Cells Ameliorate Hepatic Ischemia/Reperfusion Injury via Inhibition of Neutrophil Recruitment by Shihui Li, Xu Zheng, Hui Li, Jun Zheng, Xiaolong Chen, Wei Liu, Yan Tai, Yingcai Zhang, Genshu Wang, Yang Yang

“…In the present study, we examined the impact of MSCs on hepatic inflammatory response such as neutrophil influx and liver damage in a rat model of 70% hepatic IRI. …”
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