-
2861
Influence of Training on Employees' Performance: A Case Study of Rukiga SACCO.
Published 2025“…The study objectives included; establishing the influence of induction on employee performance in Rukiga SACCO, examining the influence of on-the-job training on employee performance in Rukiga SACCO, and determining the influence of off-the-job training and employee performance in Rukiga SACCO. …”
Get full text
Thesis -
2862
Response to Infliximab in Crohn’s Disease: Genetic Analysis Supporting Expression Profile
Published 2015-01-01“…Patients with active CD (350) who received at least three induction doses of IFX were included and classified according to IFX response. …”
Get full text
Article -
2863
Impact of hydroxyurea on clinical and biological parameters of sickle cell anemia in children in Abidjan
Published 2024-02-01“…Biochemical parameters within normal ranges, except for a moderate treatment-related increase in transaminases. Conclusion: The induction of fetal hemoglobin (Hb F) production through hydroxyurea intake is the primary mechanism by which hydroxyurea modifies the pathogenesis of sickle cell disease …”
Get full text
Article -
2864
Trials and tribulations: a qualitative exploration of researcher perspectives on navigating the challenges of health system implementation research
Published 2025-01-01“…Focus groups were transcribed verbatim and analysed using an inductive thematic approach. Barriers and facilitators identified within themes were deductively coded to domains of the updated Consolidated Framework for Implementation Research.Setting Participants were recruited from a research organisation based in Sydney, Australia.Participants A total of seven researcher and administering institution participants took part in four focus groups.Results Analysis highlighted the following themes: navigating bureaucracy, distinguishing implementation trials from clinical trials, the impact of COVID-19, balancing rigour and pragmatism in implementation trials, data access and complexity of analysis, and key learnings and future directions (subthemes: building relationships with ethics committees, communicating implementation concepts, streamlining of the implementation and research approach).Conclusions Findings highlight the need for streamlining current administrative and ethical review processes, as well as procedures that allow greater flexibility for researchers to respond to challenges as they arise. …”
Get full text
Article -
2865
Perspectives of Pharmacists Towards Patient-Centred Mental Health Pharmacy Services: A Focus Group Study
Published 2025-01-01“…Thematic analysis was performed inductively to analyse the data. Results: This study involved 14 focus group sessions with all 63 pharmacists participating. …”
Get full text
Article -
2866
Stigma reduction in a disability and mental health programme in Ghana: Lessons in participation
Published 2025-01-01“…We conducted thematic analysis using deductive and inductive approaches. Results: The programme adopted several approaches to participation at design and implementation stages, with a focus on the leadership of people with disabilities and people with mental health conditions. …”
Get full text
Article -
2867
<i>Agrobacterium rhizogenes</i>-Mediated Hairy Root Transformation in <i>Rosa</i>
Published 2025-01-01“…We explored the factors affecting the induction and transformation of hairy root cultures in rose by screening different types of explants, <i>Rosa</i> genotypes, <i>Agrobacterium</i> strains, media, and infection and co-cultivation times for genetic transformation under aseptic conditions. …”
Get full text
Article -
2868
Mineral composition and ratios in aortic valves, serum, and epicardial fat among patients with aortic stenosis undergoing aortic valve replacement
Published 2025-01-01“…Elemental composition was determined using inductively coupled plasma mass spectrometry. Analyses revealed a distinct accumulation of Ca and P in aortic valve tissues, not correlated to and exceeding that in epicardial adipose tissue, suggesting localized mineralization. …”
Get full text
Article -
2869
Preventive Effect of Cocoa Flavonoids via Suppression of Oxidative Stress-Induced Apoptosis in Auditory Senescent Cells
Published 2022-07-01“…Each cell line was divided into a control group (CTR) and an H<sub>2</sub>O<sub>2</sub> group (induction of senescence by an oxygen radical). Additionally, every group of every cell line was treated with the cocoa polyphenolic extract (CPE), measuring different markers of apoptosis, viability, the activity of antioxidant enzymes, and oxidative/nitrosative stress. …”
Get full text
Article -
2870
Caffeic acid phenethyl ester restores mitochondrial homeostasis against peritoneal fibrosis induced by peritoneal dialysis through the AMPK/SIRT1 pathway
Published 2024-12-01“…In vitro, peritoneal mesothelial cells (PMCs) treated with PDF showed inhibition of the AMPK/SIRT1 pathway, mitochondrial membrane potential depolarization, overproduction of mitochondrial reactive oxygen species (ROS), decreased ATP synthesis, and induction of mesothelial-mesenchymal transition (MMT). …”
Get full text
Article -
2871
Comparative Analysis of Preoperative Sedation Modalities: Oral Midazolam and Ketamine Versus Chloral Hydrate and Meperidine in Pediatric Tonsillectomy - A Randomized Clinical Trial
Published 2024-09-01“…Objective: A pre-anesthetic medication that is ideal for pediatric patients undergoing tonsillectomy should alleviate pediatric anxiety, facilitate the smooth induction of anesthesia, and have an analgesic effect for postoperative care. …”
Get full text
Article -
2872
Small RNA sequencing highlights potential functions of tsRNAs in regulating pyroptosis in trigeminal neuralgia
Published 2024-12-01“…The expression of caspase-1, IL-1β, and IL-18 was significantly boosted after TN induction. CoPP + H2O2 exposure induced cell injury and pyroptosis of rat Schwann RSC96 cells, but reversed by VX-765 (a caspase-1 inhibitor). …”
Get full text
Article -
2873
Metabolic adaptations to acute glucose uptake inhibition converge upon mitochondrial respiration for leukemia cell survival
Published 2025-01-01“…When wild-type and oncogenic RAS patient-derived induced pluripotent stem cell acute myeloid leukemia (AML) models were examined, KL-11743 mediated induction of mitochondrial respiration and dependency for survival associated with oncogenic RAS. …”
Get full text
Article -
2874
A microfluidics platform for simultaneous evaluation of sensitivity and side effects of anti-cancer drugs using a three-dimensional culture method
Published 2025-01-01“…Perfusion of MI organoids with toceranib also reduced viability, as observed in FMT organoids; however, this was due to the induction of necrosis rather than apoptosis. In conclusion, our established multi-organoid-on-chip system could be used to evaluate anti-cancer drug sensitivity and side effects in vitro, which might contribute to developing personalized medicine for cancer patients.…”
Get full text
Article -
2875
Use of digital data from open sources during the investigation of criminal offenses: certain aspects
Published 2024-06-01“…An analysis of national legislation, national judicial practice, the Berkeley protocol for conducting an investigation using open digital data (hereinafter referred to as the Berkeley Protocol), the practice of the European Court of Human Rights, the International Criminal Court and scientific research, based on which, by means of a synthesis, the basis of the problem was identified. Induction and deduction were used to form authors’ conclusions. …”
Get full text
Article -
2876
Promoting ER stress in a plasmacytoid dendritic cell line drives fibroblast activation
Published 2025-02-01“…Conclusions Overall, our data suggest that ER stress induction in pDCs promotes fibroblast activation, which may contribute to the development of fibrosis in SSc.…”
Get full text
Article -
2877
Reflecting on partnerships established and sustained over four cycles of a federally funded cancer prevention and control research program: lessons learned for community-academic n...
Published 2025-01-01“…As community-based participatory research is a core value of our center, we examined the development and continued engagement of our community partners using a qualitative, inductive approach to identify emergent themes from focus group sessions with current and past investigators.ResultsSeveral key themes were identified from our analysis including long-term commitment to community partnerships and interconnectedness with other work, authentic approach, valuing our community as experts, and mutual benefits.DiscussionWith our results, we provide evidence of common community-based participatory research (CBPR) principles which have supported the sustained engagement with those racial minorities who are most vulnerable in our community. …”
Get full text
Article -
2878
Phenolic Compounds from Water-Ethanol Extracts of Tetrapleura tetraptera Produced in Cameroon, as Potential Protectors against In Vivo CCl4-Induced Liver Injuries
Published 2019-01-01“…The extract of T. tetraptera was administered at doses of 50 mg/kg and 100 mg/kg for 07 per os to rats before the induction of hepatotoxicity with of 2 ml/kg of 1:1 (v/v) carbon tetrachloride (CCl4) and olive oil through intraperitoneal route. …”
Get full text
Article -
2879
Retinoic Acid Signal Negatively Regulates Osteo/Odontogenic Differentiation of Dental Pulp Stem Cells
Published 2020-01-01“…Human DPSCs were isolated and cultured in osteogenic induction medium with or without RA or BMS 493, an inverse agonist of the pan-retinoic acid receptors (pan-RARs). …”
Get full text
Article -
2880
EFFORTS IN CONTROLLING COAL DUST HAZARDS IN THE STOCKPILE AREA OF A STEAM POWER PLANT (PLTU)
Published 2022-11-01“…POMI included the installation of a spray gun, a dust suppression system, reforestation, and ventilation setting. Further, OHS induction was conducted, together with safety talk, working hour regulations, toolbox meeting, training on the use of PPE, Medical Check Up (MCU), person authorization, preventive maintenance, and the use of PPE by workers. …”
Get full text
Article