Study of the relationships of polymorphisms of the folate cycle genes with the levels of homocysteine and folic acid as risk factors of cardiovascular disorders in the post-covid p... by A.A. Shuprovych, O.V. Zinych, N.M. Kushnareva, K.P. Komisarenko

“…The study of groups of patients, divided depending on the genotype of methioninesynthase reductase at position 66, showed that carriers of the recessive homozygous 66 G/G mutation (group 3, n=15) had increased serum homocysteine level (16.56±1.64 μmol/l) in comparison with individuals of group 1 (n=17) 66 A/A (10.28±1.17 μmol/l; p=0.004) and group 2 (n=19) 66 A/G (11.32±1.17 μmol/l, p=0.013). …”
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A retrospective study of pembrolizumab combined with XELOX regimen in the treatment of advanced gastric cancer by FENG Huizhi, LIU Jingmei, BU Xiaoqian

“…Exclusion criteria: patients with concurrent major organ dysfunction; hypothyroidism or hyperthyroidism; blood or coagulation disorders; autoimmune diseases; lactating or pregnant women; individuals with mental illnesses or a history of mental illness; those with concurrent other malignancies; those with severe liver or kidney dysfunction; patients with incomplete clinical data. …”
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Perspectives and Practices of Healthcare Leaders in Supporting Healthcare Worker Well-Being: A Reality Check by Reijmerink IM, van der Laan MJ, Scheele F, Wietasch JKG

“…Interestingly, while leaders acknowledge their potential to positively influence well-being, particularly in work-related aspects, there was a notable trend of deflecting responsibility, often redirecting it towards other leaders or placing it back on the individual employee.Conclusion: Healthcare leaders show a comprehensive understanding of factors affecting employee well-being. …”
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Review and Prospect of Research on Urban Walking Safety and Environmental Influencing Factors Thereof by Lin LI, Yu YE, Yong CHEN

“…As the urban built environment is facing more and more complex conditions, the research focus extends from the analysis of individual collision accidents to the comprehensive urban environment construction. …”
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Relationship between pregnant women's combined exposure to heavy metals and their offspring's congenital heart defects in Lanzhou, China by Lulu Chen, Lulu Chen, Yaqin Zhao, Yaqin Zhao, Jianhao Sun, Jianhao Sun, Xinjuan Jiao, Zhenzhen Wu, Zhenzhen Wu, Jian Wang, Jie Qiu, Baohong Mao, Baohong Mao, Qing Liu, Qing Liu

“…BackgroundPrevious research has demonstrated that exposure to individual heavy metals elevates the incidence rate of congenital heart defects (CHDs). …”
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Influence of spine biomechanics and sagittal balance on the outcome of lumbar discectomy by José Poblete Carrizo, José Poblete Carrizo, Jesús Martínez, Julio González, Alejandra Mosteiro, Ramon Torné, Ramon Torné, Alberto Di Somma, Alberto Di Somma, José Ríos, Joaquim Enseñat, Joaquim Enseñat, Salvador Fuster, Salvador Fuster

“…Assessment of spinal sagittal balance as a prognostic factor after lumbar discectomy.ResultsCompared to healthy individuals, patients with symptomatic lumbar disc herniation showed lower thoracic kyphosis (39.03 vs. 34.42° p = 0.034), lower thoraco-lumbar transition T10-L2 angulation (6.79 vs. 2.08° p = 0.005), lower lumbar lordosis (59.54 vs. 48.36° p < 0.001) and lumbo-sacral angulation L4-S1 (40.20 vs. 29.16° p < 0.001), lower pelvic incidence (54.71vs 49.86° p = 0.014) and lower sacral slope (42.07 vs. 33.34° p < 0.001). …”
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Dynamics of cortisol levels and the state of vitamin D supply during the full-scale war in Ukraine in patients with type 2 diabetes mellitus by M.I. Bobryk, V.I. Pankiv, V.M. Yerokhovych, V.S. Yuzvenko, D.Yu. Malyi, Yu.I. Komisarenko, L.V. Mikulets

“…In 2021–2024, a prospective study was conducted, which inclu­ded patients with T2DM and a glycated hemoglobin (HbA1c) level ≥ 7 %, individuals with insulin resistance without DM and people without DM aged 19–75 years. …”
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Association of Estimated Glomerular Filtration Rate (eGFR) and High-Sensitivity C-Reactive Protein (Hs-CRP) with the Risk of New-Onset Atrial Fibrillation in Patients with Diabetes by Liu Y, Liu H, Sun D, Zheng Y, Tse G, Chen K, Qiu J, Wu S, Liu T

“…Subgroup analysis revealed that the combination of eGFR and hs-CRP had predictive value primarily in males under 60 years of age, individuals with FBG < 9 mmol/L, hypertension, and those not on hypoglycemic medications.Conclusion: In diabetic patients, decreased eGFR and elevated hs-CRP were independently linked to an increased risk of new-onset AF, emphasizing the importance of monitoring these factors for early detection and prevention of AF.Keywords: estimated glomerular filtration rate, high-sensitivity C-reactive protein, atrial fibrillation, diabetes mellitus…”
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A qualitative study on health education knowledge demands of patients after gastric cancer surgery before discharge (胃癌术后患者出院前健康教育知识需求的质性研究)... by LAI Shurong (赖淑蓉), LAI Xiaoning (赖小令), YU Xiaoqing (喻小青), HUANG Xiaoyi (黄小恬)

“…It is recommended that nursing staff should provide individualized nursing based on the specific needs of patients and offer targeted health education and support to facilitate the rehabilitation process. …”
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F. NIETZSCHE: VALIOS SIEKTI GALIOS PRINCIPAS by Arūnas Mickevičius

“…The category of „life“ for Nietzsche does not mean inactive seclusion, but activity: possessing, subduing the weaker dominance of individual shapes, annexation. So the will to power was built on a dynamic, antagonistic foundation. …”
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Synthesis, characterization, and evaluation of copper-doped zinc oxide nanoparticles anticancer effects: in vitro and in vivo experiments by Habib Ghaznavi, Mohammad Reza Hajinezhad, Zahra Hesari, Milad Shirvaliloo, Saman Sargazi, Sheida Shahraki, Eshagh Ali Saberi, Roghayeh Sheervalilou, Somayeh Jafarinejad

“…X-ray diffraction analysis confirmed the wurtzite crystal structure for both types of nanoparticles. While individual grain sizes varied, the mean particle size for all samples, including those with increasing copper doping, was approximately 100 ± 0.1 nm. …”
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A Long-Term Study of Aerobic Performance in Elite Cross-Country Skiers: How Age and Sex Influence Career Development by Elias Bucher, Jon P. Wehrlin, Grégoire P. Millet, Thomas Steiner

“…Fixed effects included age, sex, and their interaction, with random effects at the individual level. The study included 357 observations (n = 27 females, 48 males) for VO2max, 911 (n = 46 females, 65 males) for LT2, and 601 (n = 49 females, 70 males) for 24-min DP. …”
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Fifteen-second bouts of hyperoxia improve 5-minute time-trial performance in acute hypoxic conditions by Martin Faulhaber, Sina Schneider, Linda K. Rausch, Tobias Dünnwald, Verena Menz, Hannes Gatterer, Michael D. Kennedy, Wolfgang Schobersberger

“…Methods 17 healthy and recreationally trained individuals (7 females, 10 males, age 27 ± 4 years) participated in this randomized placebo-controlled cross-over trial. …”
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Epidemiología de los nematodes gastrointestinales en caprinos lecheros en los valles templados del NOA, Argentina by V.H. SUAREZ, M. FONDRAZ, A.E. VIÑABAL, G.M. MARTÍNEZ, A.O. SALATIN

“…Sólo se desparasitaron de urgencia aquellos animales que superaran los 3000 de hpg o y que presentaran signos de parasitosis. El rinde lácteo individual se midió en abril de 2010 en un grupo de cabras en ordeñe. …”
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Risk factors associated with degenerative glenohumeral osteoarthritis by Ravi Prakash, Nitin B Jain, Ziyi Chen, Folefac D Atem, Michael S Khazzam, Rashmi Pathak, Daniel Tai, Ursa BezanPetric, Estefanie Garduno Rapp

“…This study aimed to identify risk factors for GH OA.Methods We used data from the Dallas Shoulder cohort, including individuals aged 40–85. Those with confirmed GH OA based on X-ray were cases, and those without were controls. …”
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Potential pharmacological effect of Quercetin Phytosome™ in the management of hyperuricemia: results from real-life clinical studies by Francesco Di Pierro, Francesco Di Pierro, Francesco Di Pierro, Fazle Rabbani, Meherullah Tareen, Roohi Nigar, Amjad Khan, Nicola Zerbinati, Maria L. Tanda, Massimiliano Cazzaniga, Alexander Bertuccioli, Alexander Bertuccioli, Paolo Falasca, Gabriele Damiani, Nicola Villanova

“…Additionally, triglyceride-lowering benefits were evident, particularly in metabolically compromised individuals (Cohorts 2 and 3), where these effects were statistically significant. …”
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ART Regimen and Other Sociodemographics Do Not Affect Cytokine Expression in HIV Patients in Ghana by Samuel Essien-Baidoo, Dorcas Obiri-Yeboah, Yeboah Kwaku Opoku, Elvis Ayamga, Kevin Hodi Zie, Daniel Attoh, Evans Obboh, Anna Hayfron Benjamin, Justice Afrifa

“…Variations in the levels of cytokine in HIV-infected individuals significantly impact the role of the immune system with the possibility to affect the course of HIV disease by either exacerbating or suppressing HIV replication. …”
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Acceptability and Implementation Challenges of Benzathine Penicillin G Secondary Prophylaxis for Rheumatic Heart Disease in Ethiopia: A Qualitative Study by Eshetie Melese Birru, Kevin T. Batty, Laurens Manning, Stephanie L. Enkel, Brioni R. Moore

“…Insights into BPG use and acceptability were categorized into four major themes related to: (1) individual factors (e.g., fear of anaphylactic reaction), (2) health system barriers (e.g., BPG shortage), (3) patient/caregiver perceptions (e.g., reliance on injectables, over expectation of treatment outcomes), and (4) product (e.g., injection pain, needle blockage). …”
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The effect of core stabilization exercises and shock wave therapy in patients with radiculopathy by J. Bubelis

“…Thus, before the cycle of physiotherapy, individuals with radiculopathy and experiencing moderate pain are more likely to experience lower limb traumas due to dynamic changes in stability. …”
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Biological embodiment of educational attainment and future risk of breast cancer: findings from a French prospective cohort by Cyrille Delpierre, Raphaële Castagné, Eloïse Berger, Gianluca Severi, Marie-Christine Boutron-Ruault, Laura Baglietto, Laure Dossus, Amandine Gelot, Richard Dudouet

“…We focused on biomarkers from several physiological systems examined individually, and jointly through a biological health score (BHS).Design Prospective cohort study.Setting This study, based on a subsample of the French E3N cohort, included women with biological data from four nested case–control studies.Participants The study included 3048 postmenopausal women (17% BC).Main outcome measures We first evaluated the association between educational attainment and each biomarker, separately (N=11) and by combining them into a BHS, indicative of an augmented biological health hazard when elevated. …”
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