Prevalence, Pattern and Factors Associated with Developmental Delay amongst Under-5 Children in Nigeria: Evidence from Multiple Indicator Cluster Survey 2011–2017 by Olayide Olubunmi Olabumuyi, Obioma Chukwudi Uchendu, Pauline Aruoture Green

“…A semi-structured, questionnaire administered by the interviewer was used to obtain individual and household-level data. This study comprised a weighted sample of 17,373 under-5 children who had complete data from both survey rounds on characteristics deemed significant for the study. …”
Get full text

Systematic review and quantitative meta-analysis of age-dependent human T-lymphocyte homeostasis by Victoria Kulesh, Victoria Kulesh, Kirill Peskov, Kirill Peskov, Kirill Peskov, Gabriel Helmlinger, Gennady Bocharov, Gennady Bocharov, Gennady Bocharov

“…ObjectiveTo evaluate and quantitatively describe age-dependent homeostasis for a broad range of total T-cells and specific T-lymphocyte subpopulations in healthy human subjects.MethodsA systematic literature review was performed to identify and collect relevant quantitative information on T-lymphocyte counts in human blood and various organs. Both individual subject and grouped (aggregated) data on T-lymphocyte observations in absolute and relative values were digitized and curated; cell phenotypes, gating strategies for flow cytometry analyses, organs from which observations were obtained, subjects’ number and age were also systematically inventoried. …”
Get full text

Effectiveness of antipsychotic medication in patients with schizophrenia in a real world retrospective observational study in Ethiopia by Mulualem Kelebie, Getasew Kibralew, Gebresilassie Tadesse, Gidey Rtbey, Mekidem aderaw, Wondale Endeshaw, Mitiku Belachew, Mulu Muche, Diemesew Getnet, Setegn Fentahun

“…Medication adherence, symptom relapse, and suicidal thoughts significantly impacted antipsychotic effectiveness in individuals with schizophrenia disorder.…”
Get full text

The Middle to Late Triassic of Central Saudi Arabia with emphasis on the Jilh Formation. Part I: lithostratigraphy, facies and paleoenvironments, palaeontology and biostratigraphic... by Le Nindre, Yves-Michel, Vaslet, Denis, Vrielynck, Bruno, Krystyn, Leopold, Manivit, Jacques, Memesh, Abdullah, Davies, Roger Brett

“…Part II “Sequence stratigraphy, depositional and structural evolution, and regional correlations” exploits the results of Part I, providing a dynamic reconstruction and a renewed vision of the Middle to Late Triassic at the regional scale.The Jilh Formation at outcrop consists of a multilayer system of thinly bedded, mixed siliciclastics with subordinate carbonates and evaporites, representing non-marine to offshore settings. Individual beds are difficult to correlate at regional scale. …”
Get full text

Physiology and Pathophysiology of Marathon Running: A narrative Review by Lorin Braschler, Pantelis T. Nikolaidis, Mabliny Thuany, Daniela Chlíbková, Thomas Rosemann, Katja Weiss, Matthias Wilhelm, Beat Knechtle

“…Conclusion All in all, marathon training is generally safe for human health and individual organ systems. Considering the high popularity of marathon running, these findings supply athletes, coaches, sports scientists, and sports medicine practitioners with practical applications. …”
Get full text

Assessment of Health Risks from Agricultural Soils Contaminated with Polycyclic Aromatic Hydrocarbons (PAHs) Across Different Land-Use Categories of Bangladesh by Sumaya Sharmin, Qingyue Wang, Md. Rezwanul Islam, Weiqian Wang, Yanyan Wang, Christian Ebere Enyoh, Md. Sohel Rana

“…Higher concentrations were noted for individual PAHs such as Nap, Phe, BbF, and BkF (313.14 µg/kg ± 62.01 to 546.97 µg/kg ± 146.76), while the lowest concentrations were recorded for BghiP, DBahA, and Ind (1.25 µg/kg ± 1.10 to 5.74 µg/kg ± 3.77). …”
Get full text

Three-dimensional structure of entire hydrated murine hearts at histological resolution by Jasper Frohn, Frederik Böddeker, Marius Reichardt, Hendrik Bruns, Titus Czajka, Amara Khan, Ludovic Broche, Michael Krisch, Alberto Bravin, Frauke Alves, Jana Zschüntzsch, Tim Salditt

“…The high resolution dataset allows to discern individual cardiomyocytes in the tissue. All datasets have been analyzed using semi-automated image segmentation of the ventricles, rotation into a common coordinate system, classification into different anatomical compartments, and finally the structure tensor approach. …”
Get full text

The Mediating Role of Avoidant Personality Disorder Features in the Relationship Between Stressful Life Events and Depression Among First-Year University Students by Zhou H, Niu S, Guo Y, Qin Y, Sun H, Mu F, Duan X, Zheng Y, Zhang Y, Liu Y, Liu N

“…Psychological interventions for depression in college students should focus not only on stress but on individual personality traits and cognitive mode. Care-givers, teachers, and health professionals should pay more attention to the early identification of the AVPD features among university students.Keywords: stressful life events, depression, avoidant personality disorder, mediator…”
Get full text

East Asian Welfare Regimes 東アジア福祉制度 by Joseph Wong, Andrew DeWit, Ito Peng

“…By contrast, China, Singapore and Hong Kong have much more individual-focused, market-based policy regimes. These latter countries are adopting this rather counterintuitive (considering the “Asian values” culturalist emphasis on communitarianism in East Asia) approach due to restricted fiscal capacity in the central state and the lack of credibility for communitarian ideology in what are highly diverse polities.All the countries in East Asia confront rapid ageing as well as the challenge from cheap labor in the other developing countries. …”
Get full text

Assessing the potential of germplasm collections for the management of genetic diversity: the case of the French National Cryobank by Jacques, Alicia, Duclos, Delphine, Danchin-Burge, Coralie, Mercat, Marie-José, Tixier-Boichard, Michèle, Restoux, Gwendal

“…Within a breed, IDI can be computed individually and thus be used to select the best sires for a given objective. …”
Get full text

Detecting Deception and Ensuring Data Integrity in a Nationwide mHealth Randomized Controlled Trial: Factorial Design Survey Study by Krista M Kezbers, Michael C Robertson, Emily T Hébert, Audrey Montgomery, Michael S Businelle

“…This resulted in 1409 individuals being eligible after all deception checks were completed. …”
Get full text

Association of socioeconomic status with diabetic microvascular complications: a UK Biobank prospective cohort study by Yikeng Huang, Zhi Zheng, Haibing Chen, Chufeng Gu

“…Methods SES was evaluated using education attainment (individual level), household income (household level), and Townsend deprivation index (TDI, neighborhood level). …”
Get full text

Exploring the Psychological and Physiological Insights Through Digital Phenotyping by Analyzing the Discrepancies Between Subjective Insomnia Severity and Activity-Based Objective... by Ji Won Yeom, Hyungju Kim, Seung Pil Pack, Heon-Jeong Lee, Taesu Cheong, Chul-Hyun Cho

“…MethodsA total of 250 participants, including both individuals with and without insomnia aged 19-70 years, were recruited from March 2023 to November 2023. …”
Get full text

Single-Cell Transcriptome Analysis Reveals Different Immune Signatures in HPV- and HPV + Driven Human Head and Neck Squamous Cell Carcinoma by Simin Li, Yang Wang, Rui Sun, Debora Franceschi, Hongying Pan, Chenxuan Wei, Anthony Chukwunonso Ogbuehi, Bernd Lethaus, Vuk Savkovic, Sebastian Gaus, Rüdiger Zimmerer, Dirk Ziebolz, Gerhard Schmalz, Xiao Jiang

“…Results. 20,978 high-quality individual cells passed quality control. RNA-seq data were used from 522 HNSCC primary tumor samples. 1,137 differentially expressed genes between HPV+ and HPV- HNSCC patients were investigated. 96 differentially expressed genes were associated with overall survival and highly enriched in B cell associated biological process. …”
Get full text

Evaluating Whether Nonimmersion Virtual Reality Simulation Training Improves Nursing Competency in Isolation Wards: Randomized Controlled Trial by Dandan Zhang, MuLi Fu, Jianzhong Zhang, Yuxuan Li, Li Chen, Yong-Jun Chen, Zhefeng Zhong, Yin-Ping Zhang

“…A total of 90 nurses from 3 hospitals in China were randomly assigned to either the control or intervention group, with 45 (50%) individuals in each group. Both groups received training on isolation ward layout and nursing procedures. …”
Get full text

Composition and the predicted functions of fungal communities and the key drivers in acidic soils of Jiaodong Peninsula, China by Jing Liu, Zafran Gul Wazir, Guoqin Hou, Guizhen Wang, Fangxu Rong, Yuzhi Xu, Kai Liu, Mingyue Li, Aiju Liu, Hongliang Liu, Hongwen Sun

“…Redundancy analysis (RDA) revealed that soil pH as well as nitrate nitrogen (NO3−-N) and total nitrogen (TN) significantly associated with fungal community at the phylum level, whilst soil pH was the only factor significantly linked to individual fungal classes (p < 0.01 or 0.05). The further Mantel test analysis and structural equation modeling (SEM) suggested that, in contrast to the negative and directive driving of soil pH on fungal communities' variation, the specific plant pathogenic fungi, Gibberella and Didymellaceae, were significantly and positively associated with soil acidic characteristics (p < 0.05).DiscussionThese findings highlighted that, in addition to modulating the variation of soil fungal community, soil acidification might prime some plant pathogens development. …”
Get full text

Association Between Liver Fibrosis and Risk of Incident Stroke and Mortality: A Large Prospective Cohort Study by Zijie Wang, Zhitao Gong, Jianshang Wen, Shanyu Zhang, Xiao Hu, Wenliang Guo, Yanghua Tian, Qi Li

“…Noninvasive indices of liver fibrosis may serve as an easily accessible marker to detect individuals facing elevated risk of stroke and death in the primary prevention settings.…”
Get full text

Real-World Life Analysis of a Continuous Glucose Monitoring and Smart Insulin Pen System in Type 1 Diabetes: A Cohort Study by Paola Pantanetti, Giovanni Cangelosi, Sara Morales Palomares, Gaetano Ferrara, Federico Biondini, Stefano Mancin, Gabriele Caggianelli, Mauro Parozzi, Marco Sguanci, Fabio Petrelli

“…While Type 2 diabetes (T2D) is more prevalent, Type 1 diabetes (T1D) presents unique therapeutic challenges, particularly in younger individuals. Advances in diabetes management, such as continuous glucose monitoring (CGM), insulin pumps (IP), and, more recently, smart multiple dose injection (MDI) pens, have significantly enhanced glycemic control and improved patients’ quality of life. …”
Get full text

Exploring the potential association between serum selenium and hypertension in obese adult males in the United States by Bei Li, Haiyan Ma, Ying Yu, Jieli Chen, Shengnan He, Lan Yang

“…Our previous analysis of participants from the National Health and Nutrition Examination Survey (NHANES) 2011–2018 indicated that elevated serum selenium concentrations were associated with an increased risk of metabolic abnormalities in obese individuals, with the primary effect being on blood pressure in males. …”
Get full text

Distribution of Major HLA-A, -B, -DR, and -DQ Loci Potentially Associated with Multiple Sclerosis in a Healthy Population from Southern Morocco by Abir Fguirouche, Fatimazahra Ouahmani, Ikram Brahim, Raja Hazime, Nissrine Louhab, Najib Kissani, Mohamed Chraa, Brahim Admou

“…<b>Materials and Methods:</b> A cross-sectional study was carried out over the 2016–2023 period on 685 Moroccan healthy individuals, including 355 males and 330 females. Of the total sample tested, 685 underwent HLA class I typing, of which 305 also benefited from HLA class II typing. …”
Get full text