Aging-enhanced autophagy activity promotes fibrotic progression via the TGF-β2/Smad signaling pathway in trabecular meshwork cells—a new insight from POAG by Jin Han, Jun Wang, Ling Shen, Yiting Cai, Xuze Wang, Ailixiati Wumaier, Wei Chen, Wei Han

“…We observed increased autophagic activity in TM tissues from POAG patients and in TM tissues of aging healthy individuals. In human primary TM cells, we confirmed that autophagy becomes activated in the context of cellular senescence and the development of POAG, which further facilitates fibrotic progression via the TGF-β2/Smad signaling pathway. …”
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The concentration of optimum dissolved oxygen levels for growth of mangrove crab Scylla serrata seed in recirculation system by Kurnia Faturrohman, Kukuh Nirmala, Daniel Djokosetiyanto, Yuni Puji Hastuti

“…The crab with the average of body weight 45.6±2.1 g/individual cultured in a plastic box (40×30×30 cm3). …”
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Biologic Therapy and Cardiometabolic Risk in Psoriasis: A Retrospective Review by Annika Smith, Aidin Karahasan, Deborah Yi, Sanjay Yapabandara, James Elhindi, Pablo Fernandez-Penas, Clara Chow, Sarah Zaman

“…Further research in larger cohorts is needed to elucidate the benefits, if any, of biologic therapy on cardiometabolic parameters in individuals with psoriasis, in order to optimise care for this vulnerable cohort.…”
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Unmet Supportive Care Needs of Lung Cancer Survival Patients at Different Cancer Stages and Treatment Phases by Lee PY, Chen YA, Tsai TH, Chen CY, Shieh SH

“…Therefore, Healthcare professionals should provide appropriate and timely individualized care to address these needs.Keywords: unmet care needs, lung cancer, survivor, cancer stages and treatment…”
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Codicology in Lithuania in 1918-1990: Between Book History and Palaeography by Rima Cicėnienė

“…The end of the Second World War saw the reactivation of academic institutions, the training of a new generation of historians and librarians, the accumulation of manuscript books, and the appearance of individual works on the history of the book. However, we can only speak of codicological research and attention to the manuscript book as a research object since the 1980s. …”
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Culturally appropriate terminologies in health research: a participatory study with pregnant and breastfeeding mothers in Uganda by Ritah Nakijoba, Adelline Twimukye, Josephine Bayigga, Aida N. Kawuma, Simon Peter Asiimwe, Fredrick Byenume, Jacqueline Kyeyune, Sylvia Nabukenya, Francis Williams Ojara, Francis Williams Ojara, Catriona Waitt, Catriona Waitt

“…Language defining a person on the basis of anatomical or physiological characteristics was considered ‘embarrassing’ and labelling individuals based on their conditions was construed as stigmatising. …”
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Acute effect of exercise with or without the integration of cooperative activities on inhibitory control in preadolescent school children by Melanie Berger, Markus Gerber, Sebastian Ludyga

“…The nature and organization of individual differences in executive functions: Four general conclusions. …”
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Validity and reliability of the brief form of the normative male alexithymia scale among Chinese patients after radical prostatectomy by F. Wang, X. Zhang, L. Huang, X. Zhang, W. Jie, X. Chang, Y. Chu, L. Wang, W. Jia, B. Zhang

“…Developing a reliable and valid tool to measure alexithymia in post-prostatectomy patients would not only aid healthcare professionals in identifying at-risk individuals but also facilitate early intervention and targeted support. …”
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Three-way relationships between gut microbiota, helminth assemblages and bacterial infections in wild rodent populations by Bouilloud, Marie, Galan, Maxime, Dubois, Adelaide, Diagne, Christophe, Marianneau, Philippe, Roche, Benjamin, Charbonnel, Nathalie

“…Despite its central role in host fitness, the gut microbiota may differ greatly between individuals. This variability is often mediated by environmental or host factors such as diet, genetics, and infections. …”
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Meta-analysis of efficacy and safety of pembrolizumab for the treatment of advanced or recurrent cervical cancer by Xue Zhang, Wen-Jie Yin, Ai-Li Zhang, Xiao-Xiao Zhang, Li-Juan Ding, Jiao Zhang, Shu-Ting He, Jie-Ping Yan

“…Background This meta-analysis seeks to assess the efficacy and safety of pembrolizumab in individuals with advanced or recurrent cervical cancer.Methods Databases from PubMed, Embase, and the Cochrane Library were all thoroughly searched for pertinent research. …”
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Facilitators and barriers to reach and enrollment into a medically tailored meals program within a section 1115 Medicaid pilot: clinic staff perspectives by Sara C. Folta, Jessica Burch, Matthew Alcusky, Arlene S. Ash, Kurt Hager, Jean Terranova, Fang Fang Zhang, Oyedolapo Anyanwu, Zhongyu Li, Dariush Mozaffarian

“…IntroductionMedically tailored meals (MTMs) are home-delivered, nutritionally tailored meals for individuals living with complex or advanced diet-sensitive medical conditions. …”
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Editorial by Teddy Surya Gunawan

“…Similarly, the application of fuzzy logic for vehicle speed control and the development of SolatExo—a passive exoskeleton for individuals with physical disabilities—illustrate how engineering transcends traditional boundaries to address societal needs. …”
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Isoacid supplementation influences feed sorting, chewing behaviors, and enteric methane emissions differentially in mid-lactation dairy cows depending on dietary forage level by M.R.A. Redoy, S. Ahmed, M. Bulnes, D.H. Kleinschmit, M.E. Uddin

“…The particle size of each diet and ort from individual cows was measured using the Penn State Particle Separator, and a sorting index was calculated. …”
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Association between the composite dietary antioxidant index and non-alcoholic fatty liver disease: evidence from National Health and Nutrition Examination Survey 2005–2016 by Yidian Fu, Yidian Fu, Chao Jiang, Zonglin Li, Xiangyun Shi, Peiyuan Lv, Peiyuan Lv, Jingbo Zhang

“…In the fully adjusted of multivariable logistic regression, CDAI was negatively associated with NAFLD (odds ratio [OR], 0.95; 95% CI, 0.93–0.98). Furthermore, individuals in the highest quartile of CDAI were 34% less likely to have NAFLD compared to those in the lowest quartile (OR, 0.66; 95% CI, 0.52–0.85). …”
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Code-Switching in Algerian English as a Foreign Language Speakers’ Facebook Interactions: Exploring Functions and Motives by Saida Tobbi

“…By investigating this phenomenon, the study seeks to shed light on the ways multilingual individuals navigate language choices in virtual spaces. …”
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Genomic strategies to facilitate breeding for increased β-Glucan content in oat (Avena sativa L.) by Sumandeep Kaur Bazzer, Guilherme Oliveira, Jason D. Fiedler, Raja Sekhar Nandety, Jean-Luc Jannink, Melanie Caffe

“…The overall GWAS identified 73 loci, of which 15 coincided with loci identified for individual environments and 37 coincided with previously reported β-glucan QTLs not identified when performing the GWAS in single years. …”
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Fine particulate matter concentrations forecasting using long short-term memory network and meteorological inputs by T. Istiana, B. Kurniawan, S. Soekirno, A. Wihono, D.E. Nuryanto, B.A. Pertala, A. Sopaheluwakan

“…BACKGROUND AND OBJECTIVES: In metropolitan settings, the requirement to travel and participate in everyday tasks exposes numerous individuals to the harmful effects of air pollutants, specifically particulate matter 2.5, which has the potential to impact their well-being. …”
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Parental Mental Health and Child Maltreatment in the COVID-19 Pandemic: Importance of Sampling in a Quantitative Statistical Study by Lara Engelke, Claudia Calvano, Steffi Pohl, Sibylle Maria Winter, Babette Renneberg

“…This approach enables us to identify the individuals to whom the results apply and to combine findings from different studies. …”
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Association between the triglyceride-glucose index and contrast-induced nephropathy in chronic total occlusion patients undergoing percutaneous coronary intervention by Serdar Söner, Adem Aktan, Raif Kılıç, Hamdullah Güzel, Ercan Taştan, Metin Okşul, Adnan Duha Cömert, Mehmet Sait Coşkun, Hülya Tosun Söner, Tuncay Güzel

“…Methods Two hundred eighteen individuals from three separate medical centers who underwent procedural PCI between February 2010 and April 2012 and had a CTO lesion in at least one coronary artery were recruited. …”
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Do you know your PSMA-tracer? Variability in the biodistribution of different PSMA ligands and its potential impact on defining PSMA-positivity prior to PSMA-targeted therapy by Jan Heilinger, Katrin Sabine Roth, Henning Weis, Antonis Fink, Jasmin Weindler, Felix Dietlein, Philipp Krapf, Klaus Schomäcker, Bernd Neumaier, Markus Dietlein, Alexander Drzezga, Carsten Kobe

“…In this study, we aimed to compare tracer uptake intraindividually in various reference regions including liver, parotid gland and spleen as well as the respective tumor-to-background ratios (TBR) of different 18F-labeled PSMA ligands to today’s standard radiopharmaceutical 68Ga-PSMA-11 in a series of patients with biochemical recurrence of prostate cancer who underwent a dual PSMA-PET examination as part of an individualized diagnostic approach. Results Differences in background activity among different PSMA-PET tracers lead to variations in tumor-to-background ratios (TBR). …”
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