Prevalence and influencing factors of the dyadic psychological stress among patients with lung cancer and their family caregivers: a cross-sectional study by Juan Li, Chan Li, Jie Zou, Fang-Qun Cheng, Li Peng, Li-Hong Deng, Pei-Pei Wu, Sai-Yu Gao, Zhi-Yao Xiong, Ying Zuo, Yan Luo, Xiao-Hua Rao, Bo Yuan, Ou-Ying Chen, Jing-Ping Zhang

Get full text

Joint association of systemic immune-inflammation index and phenotypic age acceleration with chronic respiratory disease: a cross-sectional study by Yuan Zhan, Ruonan Yang, Jie Feng, Genlong Bai, Xiangyun Shi, Jiaheng Zhang, Jingbo Zhang

“…Furthermore, the joint-indexes analysis revealed that compared to individuals with lower SII and PhenoAgeAccel, those with higher SII and PhenoAgeAccel exhibited remarkably stronger associations with CRD (adjusted OR [aOR], 1.56; 95% CI, 1.31–1.85; P < 0.001), chronic obstructive pulmonary disease (aOR, 1.56; 95% CI, 1.22-2.00; P = 0.001) and asthma (aOR, 1.40; 95% CI, 1.16–1.70; P = 0.001), which were predominant among those aged above 40 years, females and smokers. …”
Get full text

EFFECTS OF SMOKING ON CIRCADIAN ARTERIAL BLOOD PRESSURE PROFILE IN PATIENTS WITH NON-ST-SEGMENT ELEVATION ACUTE CORONARY SYNDROME AND CHRONIC KIDNEY DISEASE by Oksana Yadzhyn, Tetiana Solomenchuk

“…The patients were divided into 2 groups: Group I - 35 smokers (mean age - 60.09±1.66 years), Group II - 35 individuals who have never smoked (mean age - 62.31±1.04 years). …”
Get full text

Does digital, multimedia information increase recruitment and retention in a children’s wrist fracture treatment trial, and what do people think of it? A randomised controlled Stud... by Jacqueline M Martin-Kerry, Peter Knapp, Steven Higgins, Rebecca Sheridan, Juul Achten, Duncan Appelbe, Louise Spoors, Thirimon Moe-Byrne, Daniel Perry, Jenny Roche

“…Secondary outcomes were Decision-Making Questionnaire (nine Likert items, analysed summatively and individually), three ‘free text’ questions (deriving subjective evaluations) and trial retention.Results MMI produced a small, not statistically significant increase in recruitment: 475 (69.8%) participants were recruited from the MMI group; 484 (66.5%) from the PIS group (OR=1.35; 95% CI 0.76 to 2.40, p=0.31). …”
Get full text

Preterm preeclampsia screening and prevention: a comprehensive approach to implementation in a real-world setting by Stefania Ronzoni, Shamim Rashid, Aimee Santoro, Elad Mei-Dan, Jon Barrett, Nanette Okun, Tianhua Huang

“…Methods A prospective cohort study involved pregnant individuals undergoing nuchal translucency scans between 11 and 14 weeks. …”
Get full text

Dataset of SARS-CoV-2 spike protein receptor binding domain variants in complex with antigen-binding fragments targeting COVID-19 vaccine-referenced variantsModel Archive by Ferdinando Spagnolo, Florigio Lista, Claudia Curcio

“…For each variant, the homology-modeled RBDs were complexed with the Fab fragments from 8GPY, 8H7Z, and 8XE9 by grafting them onto the RBDs, followed by energy minimization, both individually and in combination. This process resulted in a comprehensive dataset of RBD-Fab complexes, suitable for comparative analysis and further investigations.Binding affinities between the RBD-Fab pairs were calculated using the Prime MM-GBSA tool (VSGB solvation model and OPLS4 force field), enabling the ranking of antigen-antibody interactions. …”
Get full text

Informal Caregivers Connecting on the Web: Content Analysis of Posts on Discussion Forums by Michelle L Foster, Chinenye Egwuonwu, Erin Vernon, Mohammad Alarifi, M Courtney Hughes

“…Researchers extracted the first 6 responses to the first 20 questions and comments to appear posted by the informal caregivers in each of the 5 forums, removing any individually identifying information. We used a codebook thematic analysis approach to examine the data with Dedoose (SocioCultural Research Consultants). …”
Get full text

Usefulness of Automatic Speech Recognition Assessment of Children With Speech Sound Disorders: Validation Study by Do Hyung Kim, Joo Won Jeong, Dayoung Kang, Taekyung Ahn, Yeonjung Hong, Younggon Im, Jaewon Kim, Min Jung Kim, Dae-Hyun Jang

“…The z scores between SLPs and ASR showed more pronounced differences with the APAC than the U-TAP, with 8 individuals showing discrepancies in the APAC compared to 2 in the U-TAP. …”
Get full text

Perceived benefits and challenges one year after receiving brief therapy in a district psychiatric centre. An exploration of patients' and GPs' experiences: A qualitative study. by Hilde V Markussen, Lene Aasdahl, Petter Viksveen, Marit B Rise

“…<h4>Methods</h4>We conducted individual interviews with a total of seventeen participants, consisting of eleven patients and six GPs. …”
Get full text

Transition to home after very preterm birth: improving outcomes of children and their families—a systematic review protocol by Beatrice Latal, Ulrike Held, Ursula Kiechl-Kohlendorfer, Sandra Siegfried, Vivienne Engel, Valentina Mauron-Papadimitriou, Lea Bührer, Laura Ebner, Lena Keller, Martina Gosteli

“…Subsequently, it will show the individual effect of these interventions and pool effect sizes if possible. …”
Get full text

Impact of the Late Miocene Cooling on the loss of coral reefs in the Central Indo-Pacific by B. F. Petrick, L. Reuning, M. Pfeiffer, G. Auer, L. Schwark

“…This suggests the overall impact of the LMC was to increase the stress on reef systems, which could have provided a driver for the collapse of individual reefs and therefore a potential cause for the Pliocene Reef Gap. …”
Get full text

Exploring the role of inflammatory biomarkers in trigeminal neuralgia by Shenglong Lai, Haiyang Li, Yazhou Xing, Du Wu, Lin Wang, Qinghua Liang

“…Methods: A two-sample MR approach was employed using genome-wide association study (GWAS) data from 8293 Finnish individuals for inflammatory cytokines and data from the FinnGen database for TN. …”
Get full text

A Muscle Physiology-Based Framework for Quantifying Training Load in Resistance Exercises by Frank Imbach, Stéphane Perrey, Thomas Brioche, Robin Candau

“…Methods: Following individual torque–velocity profiling, fifteen participants (11 healthy males, stature: 178.36 ± 3.95 cm, and body mass (BM): 77.48 ± 7.74 kg; 4 healthy females, stature: 169.25 ± 5.03 cm, and body mass: 60.62 ± 3.91 kg) performed isokinetic leg extension exercise sessions at low, moderate, and high intensities (LI, MI, and HI, respectively). …”
Get full text

Association of composite dietary antioxidant index with circadian syndrome: evidence from NHANES by Chen Chen, Chenyu Zhao, Hongyu Jin, Zhiping Jiang, Wei Wang, Wen-Yang Li

“…Subgroup analysis showed BMI modified the inverse association between CDAI and CircS (p for interaction = 0.003).ConclusionThis study revealed a non-linear and negative association between CDAI and CircS risk, with a U-shaped correlation observed between Zinc and CircS. Obese individuals might not benefit from excessively high CDAI. …”
Get full text

Anti-inflammatory Effects of Empagliflozin and Gemigliptin on LPS-Stimulated Macrophage via the IKK/NF-κB, MKK7/JNK, and JAK2/STAT1 Signalling Pathways by Nami Lee, Yu Jung Heo, Sung-E Choi, Ja Young Jeon, Seung Jin Han, Dae Jung Kim, Yup Kang, Kwan Woo Lee, Hae Jin Kim

“…Empagliflozin and gemigliptin (individually and combined) inhibited prostaglandin E2 (PGE2) release and COX-2, iNOS gene expression in LPS-stimulated RAW 264.7 macrophages. …”
Get full text

Predicting pediatric patient rehabilitation outcomes after spinal deformity surgery with artificial intelligence by Wenqi Shi, Felipe O. Giuste, Yuanda Zhu, Ben J. Tamo, Micky C. Nnamdi, Andrew Hornback, Ashley M. Carpenter, Coleman Hilton, Henry J. Iwinski, J. Michael Wattenbarger, May D. Wang

“…Results The best prediction model achieves an area under receiver operating curve (AUROC) performance of 0.86, 0.85, and 0.83 for individual SRS-22R question response prediction over three-time horizons from pre-operation to 6-month, 1-year, and 2-year post-operation, respectively. …”
Get full text

Healthy aging in frail older adults: Active aging project of a national survey by Jisu Seo, Kyungok Joo, Yuelin Li, Nayoung Kim, Eunna Oh, Lkhagvajav Gansukh, Rhayun Song

“…Health promotion strategies could focus on resilience and social support to empower individuals and strengthen social connectedness, thereby supporting independence in daily life and healthy aging. …”
Get full text

Integrating Hybrid Team-Based and Case-Based Learning in Dental Education Transformation by Sidra Abid, Humna Rafiq

“…Never do Hybrid TBL processes focus on passive learning, as both team spirit and individualism are encouraged. Instead, it is a more interactive process in that students are required to contribute in discussions, exchange ideas based on case study readings, or even collaborate in project teams. …”
Get full text

A workplace-based HIV self-testing intervention as a determinant for self-testing knowledge, beliefs, and use among unskilled workers in Wakiso Uganda by Gerald Mukisa Nsereko, Khamisi Musanje, Eron Robinah Ayesiga, Loyce Kiiza Kobusingye, Rhoda Namubiru, Moses Sempala, Christine Kiwala, Martin Mabunda Baluku

“…Multiple regression model showed that HIVST knowledge and individual beliefs predict 37.2% [F(11,34) = 3.485, p ≤.05] of the variance in HIVST use and the overall biggest predictor of HIVST use was perceived susceptibility 53.7% (Beta = 0.537, t = 2.44, p ≤.05). …”
Get full text

Study on the changes and influencing factors of depression in Chinese women with cancer: an analysis based on CHARLS panel data by Na Wang, Mengran Chang, Shidong Liu, Bing Chen

“…In view of this, there is an urgent need for introducing more supportive policies aimed at improving psychological health, developing tailored measures to address the specific needs of different groups, intensifying efforts to standardize the diagnosis and treatment of depression, particularly for those in rural areas, central and western regions, and among individuals with lower educational levels. Additionally, the role of social participation activities, such as visiting neighbors and exercising, should be given full play to alleviate depressive symptoms.…”
Get full text