Factors Responsible For School Dropout At Different Levels of Education in Selected Academic Institutions in Kisoro Municipality Southern Division Kisoro District. by Kamahoro, Phionah

“…A cross-sectional research design was used to generate the information by explaining to the individual respondents the gist of the study. The population of the Study included SMC members, municipality education officials, head teachers, and their deputies, students, and teachers. …”
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Effects of Agrochemicals on Soil Bio-Physico-Chemical Properties in Potato Production Systems in the Highlands of South Western Uganda. by Twebaze, Jeniffer

“…Termites were significantly higher than other macro-organisms (p<0.05), but for the rest of the organisms (earthworms, beetles, and millipedes), there were no significant differences in individual populations (p>0.05). The findings of the study further revealed that the majority of potato farmers (>90%) rely on the use of agrochemicals. …”
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Factors Affecting the Teaching and Learning of English Language in Primary Schools in Kitumba Sub-County Kabale District. by Owomugisha, Justine

“…The findings obtained in the study indicated that the effect of the factors affecting the teaching and learning of English in Primary schools were reduced access to quality learning resources, ineffective teaching methods, poor Pupil outcomes, lack of support at home, decreased motivation, limited individual attention, poor classroom control, difficulty in comprehension, slower language acquisition, challenges in curriculum delivery, teacher frustration and distraction. …”
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Cerebral Cortical Activity During Academic Stress Amongst Undergraduate Medical Students at Kampala International University (Uganda) by Mujinya, Regan, Kalange, Muhamudu, Ochieng, Juma John, Ninsiima, Herbert Izo, Eze, Ejike Daniel, Afodun, Adam Moyosore, Nabirumbi, Ritah, Sulaiman, Sheu Oluwadare, Kairania, Emmanuel, Echoru, Isaac, Okpanachi, Alfred Omachonu, Matama, Kevin, Asiimwe, Oscar Hilary, Nambuya, Grace, Usman, Ibe Michael, Obado, Osuwat Lawrence, Zirintunda, Gerald, Ssempijja, Fred, Nansunga, Miriam, Matovu, Henry, Ayikobua, Emmanuel Tiyo, Nganda, Ponsiano Ernest, Onanyang, David, Ekou, Justine, Musinguzi, Simon Peter, Ssimbwa, Godfrey, Keneth Iceland, Kasozi

“…Also, highly stressed individuals had higher TRT and ART and low VRT. SS had high VRT and ART and low TRT in preclinical students, demonstrating the importance of the visual cortex in stress plasticity. …”
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A mechanistic-statistical approach to infer dispersal and demography from invasion dynamics, applied to a plant pathogen by Saubin, Méline, Coville, Jérome, Xhaard, Constance, Frey, Pascal, Soubeyrand, Samuel, Halkett, Fabien, Fabre, Frédéric

“…However, accurately inferring LDD is challenging as it requires both large-scale data and a methodology that encompasses the redistribution of individuals in time and space. Here, we propose a mechanistic-statistical framework to estimate dispersal from one-dimensional invasions. …”
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Archaea methanogens are associated with cognitive performance through the shaping of gut microbiota, butyrate and histidine metabolism by Andrea Fumagalli, Anna Castells-Nobau, Dakshat Trivedi, Josep Garre-Olmo, Josep Puig, Rafel Ramos, Lluís Ramió-Torrentà, Vicente Pérez-Brocal, Andrés Moya, Jonathan Swann, Elena Martin-Garcia, Rafael Maldonado, José Manuel Fernández-Real, Jordi Mayneris-Perxachs

“…Interestingly, methanogen archaeas exhibited the strongest positive associations with cognition, particularly Methanobrevibacter smithii (M. smithii). Stratifying individuals by median-centered log ratios (CLR) of M. smithii (low and high M. smithii groups: LMs and HMs) revealed that HMs exhibited better cognition and distinct gut bacterial profiles (PERMANOVA p = 0.001), characterized by increased levels of Verrucomicrobia, Synergistetes and Lentisphaerae species and reduced levels of Bacteroidetes and Proteobacteria. …”
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Liver damage in patients living with HIV on antiretroviral treatment with normal baseline liver function and without HBV/HCV infection: an 11-year retrospective cohort study in Gua... by Jun Yu, Hao Liang, Fengxiang Qin, Junjun Jiang, Chunwei Qin, Yunxuan Huang, Bingyu Liang, Yuexiang Xu, Jiegang Huang, Zhiliang Xu, Chuanyi Ning, Yanyan Liao, Ning Zang, Jingzhen Lai, Wudi Wei, Li Ye, Xionglin Qin

“…Objective To characterise the association between duration of exposure to antiretroviral treatment (ART) and liver damage in HIV patients with an initially normal baseline liver function and without hepatitis B virus (HBV)/hepatitis C virus (HCV) infection.Methods A retrospective cohort study was conducted in HIV-infected individuals with normal liver function parameters at ART initiation and without HBV/HCV infection, from 14 April 2004 to 13 April 2015 in Guigang city, Guangxi, China. …”
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CFTR Expression Analysis for Subtyping of Human Pancreatic Cancer Organoids by Alexander Hennig, Laura Wolf, Beatrix Jahnke, Heike Polster, Therese Seidlitz, Kristin Werner, Daniela E. Aust, Jochen Hampe, Marius Distler, Jürgen Weitz, Daniel E. Stange, Thilo Welsch

“…Organoid cultures of human pancreatic ductal adenocarcinoma (PDAC) have become a promising tool for tumor subtyping and individualized chemosensitivity testing. PDACs have recently been grouped into different molecular subtypes with clinical impact based on cytokeratin-81 (KRT81) and hepatocyte nuclear factor 1A (HNF1A). …”
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Biologically targeted discovery-replication scan identifies G×G interaction in relation to risk of Barrett’s esophagus and esophageal adenocarcinoma by Li Yan, Qianchuan He, Shiv P. Verma, Xu Zhang, Ann-Sophie Giel, Carlo Maj, Kathryn Graz, Elnaz Naderi, Jianhong Chen, Mourad Wagdy Ali, Puya Gharahkhani, Xiang Shu, Kenneth Offit, Pari M. Shah, Hans Gerdes, Daniela Molena, Amitabh Srivastava, Stuart MacGregor, Claire Palles, René Thieme, Michael Vieth, Ines Gockel, Thomas L. Vaughan, Johannes Schumacher, Matthew F. Buas

“…The strongest evidence for secondary replication was for rs17744726×rs3217992 among males, with consistent directionality across all cohorts (Pmeta = 2.19 × 10−8); rs3217992 “T” was associated with reduced risk only in individuals homozygous for rs17744726 “G.” Rs3217992 maps to the CDKN2B 3′ UTR and reportedly disrupts microRNA-mediated repression. …”
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Knowledge of COVID-19 and the psychological status of parents: a retrospective survey in Wuhan, Hubei by Lei Wang, Jing Cheng, Lin Lv, Yaqi Xu, Yutong Zhang, Honghui Gan, Change Xiong, Guiping Wang, Can Mei, Linwanyue Chen, Lu He, Shuliu Pan, Jianbo Zhan

“…However, priority attention and care should be given to individuals who have experienced mental distress in relation to the pandemic.…”
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Characteristics of tongue coating microbiota in diabetic and non-diabetic kidney patients receiving hemodialysis by Qiang Luo, Siyuan Chu, Yongqun Wu, Lingling Jin, Rui Liu, Yulin Xu, Yina Yu, Yawei Jin, Luckress Ornelle Edouarda Phyfamin Houndekon, Heshen Hu, Yvchen Zou, Hao Huang, Haimin Chen

“…Furthermore, correlations were identified between the microbiome composition and clinical parameters of the individuals. Conclusion In conclusion, deciphering the tongue coating microbiota of kidney patients undergoing hemodialysis will helpful in assessing the role of oral microbiota in pathobiology and development of kidney disease, which is expected to become a potential biomarkers and adjuvant therapeutic target.…”
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Feasibility and preliminary efficacy of a physical activity intervention in adults with lymphoma undergoing treatment by Juliana V. Costa, Alexander R. Lucas, Shannon L. Mihalko, Peter H. Brubaker, Alexandra Marshall, Brianna Leitzelar, Brianna R. Wolle, Samuel Norton, R. Lee Franco, Jeremy Via, Victor Yazbeck, Rakhee Vaidya, Mary Beth Seegars, Ralph D’Agostino, Lynne Wagner, W. Gregory Hundley

“…Results One hundred and forty-five individuals were screened with 23 of 84 eligible patients agreeing to participate (27%). …”
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Typological and cumulative approaches to risk and adversity in Child and Adolescent Mental Health Services (CAMHS): Retrospective cohort analysis in South London by Barry Coughlan, Nicole Marshall, Matt Woolgar, Julia Mannes, Paige Erkiert, Ayla Humphrey, Jack Smith, Taliah Drayak, Francesca Crozier-Roche, Tessa Morgan, Dustin Hutchinson, David Graham, Rick Hood, Robbie Duschinsky

“…Associations between individual risk typologies and psychiatric diagnosis and service activity are discussed. …”
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Cancer type-specific adverse events of immune checkpoint inhibitors: A systematic review and meta-analysis by Xuhui Tong, Rong Tang, Jin Xu, Wei Wang, Qiong Du, Si Shi, Xianjun Yu

“…In anti-PD-1 monotherapy group, melanoma patients experienced the most frequent fatigue (31.1 %, 95 % CI 29.7%–32.5 %); the incidences of severe pneumonitis and other respiratory disorders were highest in Hodgkin lymphoma (4.1 %, 95 % CI 1.5%–8.6 %; 4.1 %, 95 % CI 1.5%–8.6 %, respectively). Among individuals undergoing single-agent anti-PD-L1, higher frequency of all-grade pruritus occurred in 19.0 % of renal cell carcinoma (RCC) patients (95 % CI 15.2%–23.2 %), and the highest probability of developing other severe musculoskeletal disorders was observed in patients with RCC (6.2 %, 95 % CI 4.0%–9.0 %). …”
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Thulium laser enucleation of the prostate plus thulium fiber laser therapy for benign prostatic hyperplasia combined with bladder stones by Chen Wang, Yuanwei Li, Yongjun Yang, Junjie Chen, Zhuo Li, Guangqing Song, Jia Chen, Liu Zhe, Yili Teng, Qiang Lu

“…Results: The patients in the observation group exhibited lower surgery duration, smaller postoperative decrease in Hb levels, shorter duration of postoperative indwelling catheterization, and proportion of American Society of Anesthesiologists (ASA) II patients, with a higher proportion of ASA I patients than the individuals in the control group (P <⁠0.05). Additionally, in comparison with the control group, the patients in the observation group had lower postoperative IPSS scores and higher levels of Hb, Qmax, and QoL score (P <⁠0.05). …”
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Bearberry in the treatment of acute uncomplicated cystitis (BRUMI): protocol of a multicentre, randomised double-blind clinical trial by Péter Hegyi, Noémi Gede, Szilárd Váncsa, Barbara Tóth, András Jávorházy, Péter Nyirády, Boglárka Csupor-Löffler, Péter Birinyi, George Zhanel, Kurt Naber, Reinhard Länger, Nóra Vörhendi, Dezső Csupor

“…The antimicrobial activity of its extracts and some of its individual constituents has been observed in vitro; however, the efficacy of bearberry compared with standard antimicrobial therapy has not been assessed yet.Objective The objective of the study is to assess the safety and non-inferiority of bearberry as an alternative therapy in the treatment of acute uncomplicated cystitis in comparison with standard antibiotic therapy (fosfomycin).Methods and analysis This is a randomised controlled double-blinded multicentre trial. …”
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Developing a risk score using liquid biopsy biomarkers for selecting Immunotherapy responders and stratifying disease progression risk in metastatic melanoma patients by Amalia Azzariti, Simona De Summa, Tommaso M. Marvulli, Ivana De Risi, Giuseppe De Palma, Roberta Di Fonte, Rossella Fasano, Simona Serratì, Sabino Strippoli, Letizia Porcelli, Michele Guida

“…Pilot validations highlighted the potential use of the risk score in treatment-naive individuals and long responders. Conclusion In summary, risk score based on circulating sCTLA-4 and sCD74 reflects the response to immune checkpoint inhibitor (ICI) therapy in MM patients. …”
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Growth Performance, Serum Biochemical Profile, Oxidative Status, and Fertility Traits in Male Japanese Quail Fed on Ginger (Zingiber officinale, Roscoe) Essential Oil by Tchoffo Herve, Kana Jean Raphaël, Ngoula Ferdinand, Folack Tiwa Laurine Vitrice, Adoum Gaye, Moussa Mahamat Outman, Ngouozeu Moyo Willy Marvel

“…At the same period, 4 mature male quails per treatment were chosen at random and individually housed in cages, each with four untreated females for fertility and hatchability traits. …”
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Effects of public roads on wildlife-vehicle collisions in two protected areas, Hluhluwe-iMfolozi Park and iSimangaliso Wetland Park, in KwaZulu-Natal, South Africa by Cameron T. Cormac, Cormac Price, Wendy Collinson, Dave J. Druce, Jarryd P. Streicher, Colleen T. Downs

“…Amphibians experienced the highest number of mortalities, 1066 individuals, while birds had the highest species diversity in the mortality record with 31 identified species. …”
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Needs for rehabilitation in China: Estimates based on the Global Burden of Disease Study 1990–2019 by Tian Tian, Lin Zhu, Qingzhen Fu, Shiheng Tan, Yukun Cao, Ding Zhang, Mingxue Wang, Ting Zheng, Lijing Gao, Daria Volontovich, Yongchen Wang, Jinming Zhang, Zhimei Jiang, Hongbin Qiu, Fan Wang, Yashuang Zhao, Rongman Jia

“…It is predicted that over two in five people will require rehabilitation by 2034, thus suggesting the need to develop rehabilitation services that meet individuals’ rehabilitation needs.…”
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