Exacerbation of Pulmonary Fibrosis Following Single Lung Transplantation by Dawei Yang, Jennifer M Wilson, Chunxue Bai, John Yee, Pearce G Wilcox, Nasreen Khalil, Robert D Levy

“…Following single lung transplantation, patients receive maintenance immunosuppression, which could mitigate the development of acute exacerbations in the native lung. …”
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Potentially paraneoplastic glomerulopathies in a Brazilian cohort: a retrospective analysis by Marcella Soares Laferreira, Gianna Mastroianni Kirsztajn

“…The dose of the immunosuppressive agents among patients with neoplasms before or after immunosuppression was not statistically different. …”
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Macrophages in Tumor Microenvironments and the Progression of Tumors by Ning-Bo Hao, Mu-Han Lü, Ya-Han Fan, Ya-Ling Cao, Zhi-Ren Zhang, Shi-Ming Yang

“…In most tumors, the infiltrated macrophages are considered to be of the M2 phenotype, which provides an immunosuppressive microenvironment for tumor growth. Furthermore, tumor-associated macrophages secrete many cytokines, chemokines, and proteases, which promote tumor angiogenesis, growth, metastasis, and immunosuppression. …”
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Skin Abscess due to Serratia marcescens in an Immunocompetent Patient after Receiving a Tattoo by J. Diranzo García, J. Villodre Jiménez, V. Zarzuela Sánchez, L. Castillo Ruiperez, A. Bru Pomer

“…To our knowledge, this is the first reported case of a S. marcescens skin infection following a tattoo, in the absence of immunosuppression.…”
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Fertility, gestation outcome and parasite congenital transmissibility in mice infected with TcI, TcII and TcVI genotypes of Trypanosoma cruzi. by Sabrina Cencig, Nicolas Coltel, Carine Truyens, Yves Carlier

“…The occurrence of congenital infection was evaluated by microscopic examination of blood and/or qPCR on blood and heart in newborn pups and/or older offspring submitted to cyclophosphamide-induced immunosuppression in order to detect possible cryptic congenital infection. …”
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Collecting Duct Carcinoma of the Native Kidney in a Renal Transplant Recipient by Ian Zheng, Mahmoud Alameddine, Yaohong Tan, Zhobin Moghadamyeghaneh, Joshua S. Jue, Ali Yusufali, Ahmed Farag, Gaetano Ciancio

“…To our knowledge, CDC in the setting of renal transplant and long-term immunosuppression has not been previously described.…”
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Resolution of Mild Ganciclovir-Resistant Cytomegalovirus Disease with Reduced-Dose Cidofovir and CMV-Hyperimmune Globulin by Samir J. Patel, Samantha A. Kuten, Richard J. Knight, Dana M. Hong, A. Osama Gaber

“…Management of ganciclovir-resistant CMV may be complicated by nephrotoxicity which is commonly observed with recommended therapies and/or rejection induced by “indirect” viral effects or reduction of immunosuppression. Herein, we report a series of four high serologic risk (donor CMV positive/recipient CMV negative) kidney transplant patients diagnosed with ganciclovir-resistant CMV disease. …”
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Review of the Early Diagnoses and Assessment of Rejection in Vascularized Composite Allotransplantation by Ravi Starzl, Gerald Brandacher, W. P. Andrew Lee, Jaime Carbonell, Wensheng Zhang, Jonas Schnider, Vijay Gorantla, Stefan Schneeberger, Xin Xiao Zheng

“…Many of the challenges that have historically been limiting factors in transplantation, such as rejection and the morbidity of immunosuppression, remain challenges in VCA. Because of the accessibility of most VCA grafts, and the highly immunogenic nature of the skin in particular, VCA has become the focal point for cross-disciplinary approaches to developing novel approaches for some of the most challenging immunological problems in transplantation, particularly the early diagnoses and assessment of rejection. …”
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Innovative immunotherapies and emerging treatments in type 1 diabetes management by Malek Zarei, Mohammad Abbas Sheikholeslami, Masoud Mozaffari, Yassar Mortada

“…Beta cell therapies, including islet transplantation, offer promising outcomes but face challenges related to immunosuppression and donor availability. Stem cell therapies, particularly using mesenchymal stem cells (MSCs) and autologous hematopoietic stem cells (HSCs), demonstrate potential in immune modulation and beta cell regeneration. …”
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Health-Related Quality of Life after Pediatric Liver Transplantation: A Qualitative Analysis of the Perspectives of Health Care Providers by Mar Miserachs, David B. Nicholas, Anthony R. Otley, Vicky Lee Ng

“…HCP identified elements that both enhance (improved physical health, peer relationship, and activities of daily living) and challenge (need for immunosuppression, transplant follow-up, and restrictions) the multidimensional domains of HRQoL. …”
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Interleukin 28B polymorphism impact on early HCV kinetics in HCV-infected liver transplant recipients undergoing antiviral therapy by V. E. Syutkin, V. P. Chulanov, I. V. Karandashova, V. A. Dolgin, A. O. Chugunov

“…Genotype C/C (rs12979860) was present in 6 (40%) patients with complete EVR and in none of slow-responders (one-sided p=0.041).The groups of recipients with and without complete EVR were comparable with sex, age, pre-treatment viral load, immunosuppression (cyclosporine vs. tacrolimus), weight and body mass index, and mean ribavirin dose. …”
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De Novo Onset of Myasthenia Gravis after Kidney Transplantation by Aaron de Souza, Rajesh Raj

“…This illness is surprising since immunosuppression after transplant is usually sufficient to prevent immune-mediated disease. …”
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Evaluation of CD4+ T Lymphocyte Counts to Predict Survival of ICU Patients with Sepsis Using Sepsis-3 Criteria: A Prospective Cohort Study by Guoge Huang, Xusheng Li, Chunmei Zhang, Haizhong Li, Mengling Jian, Chunyang Huang, Yingqin Zhang, Luhua Xian, Hongke Zeng, Yuanyuan Xia, Wenqiang Jiang

“…Sepsis remains a major health condition with a high mortality rate that may be related to immunosuppression. T lymphocyte subsets may reflect the immune function of sepsis patients. …”
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Feasibility and Safety of Bariatric Surgery in High-Risk Patients: A Single-Center Experience by Yusef Moulla, Orestis Lyros, Matthias Blüher, Philipp Simon, Arne Dietrich

“…., 2016) at least one of the following risk factors was met: age ≥ 70 years, body mass index (BMI) > 70 kg/m2, liver cirrhosis, end-organ failure, or immunosuppression by status after organ transplantation along with (Birkmeyer et al., 2010) at least two comorbidities associated with obesity. …”
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Cancer vaccines: platforms and current progress by Wanting Lei, Kexun Zhou, Ye Lei, Qiu Li, Hong Zhu

“…Overcoming barriers such as effective antigen identification, immunosuppressive microenvironments, and adverse effects is critical for advancing vaccine development. …”
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Modulatory Effects of Astragalus Polysaccharides on T-Cell Polarization in Mice with Polymicrobial Sepsis by Yu-Chen Hou, Jin-Ming Wu, Ming-Yang Wang, Ming-Hsun Wu, Kuen-Yuan Chen, Sung-Ling Yeh, Ming-Tsan Lin

“…Treatments with 100 and 200 mg APS/kg BW reduced Treg populations and elicited a more-balanced Th1/Th2 response that consequently attenuated immunosuppression in polymicrobial sepsis. High-dose APS administration led to excessive responses of Th17 cells which may have adverse effects in sepsis-induced organ injury.…”
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Severe Disabling Myalgia as an Initial Presentation of Polyarteritis Nodosa by H. M. Senarathna, C. L. Fonseka, H. A. S. Perera, P. U. T. De Silva, T. P. Weerarathna

“…With continuation of aggressive immunosuppression and rehabilitation for five months, the patient improved and was able to walk without support. …”
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Divergent Crosstalk Between Microglia and T Cells in Brain Cancers: Implications for Novel Therapeutic Strategies by Min-Hee Yi, Jinkyung Lee, Subin Moon, EunA So, Geonhyeok Bang, Kyung-Sub Moon, Kyung-Hwa Lee

“…The precise mechanisms underlying microglial interactions with T cells and their contributions to immunosuppression remain incompletely understood. <b>Methods</b>: This review comprehensively examines the complex cellular dialogue between microglia and T cells in two prominent brain malignancies: primary glioblastoma and secondary brain metastases. …”
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Serological and Molecular Diagnosis of Human Cytomegalovirus among Hemodialysis Patients in Kirkuk/Iraq by Eman Ammar Ihsan, Lezan Medhat Mohammed, Waleed Mohammed Ali

“…Patients exposed to CMV during dialysis may cause virus reactivation by immunosuppression and inflammation, suggesting that screening patients is necessary to avoid complications like kidney transplant rejection. …”
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Alginate Microencapsulation of Human Islets Does Not Increase Susceptibility to Acute Hypoxia by I. K. Hals, A. M. Rokstad, B. L. Strand, J. Oberholzer, V. Grill

“…Islet transplantation in diabetes is hampered by the need of life-long immunosuppression. Encapsulation provides partial immunoprotection but could possibly limit oxygen supply, a factor that may enhance hypoxia-induced beta cell death in the early posttransplantation period. …”
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