A Rare Occurrence of Primary Hepatic Leiomyosarcoma Associated with Epstein Barr Virus Infection in an AIDs Patient by Haritha Chelimilla, Kanthi Badipatla, Ariyo Ihimoyan, Masooma Niazi

“…Close association of Epstein Barr virus (EBV) induced soft tissue sarcomas is proven, especially in the presence of immunosuppression encountered in HIV/AIDS patients and in posttransplant patients. …”
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NF-κB signaling and the tumor microenvironment in osteosarcoma: implications for immune evasion and therapeutic resistance by Shaoyan Shi, Xuehai Ou, Chao Liu, Rui Li, Qianjin Zheng, Leiming Hu

“…This research aimed to explore how NF-κB influences the recruitment and polarization of tumor-associated macrophages and myeloid-derived suppressor cells, both of which contribute to immunosuppression. Furthermore, NF-κB facilitates immune surveillance evasion in osteosarcoma cells by altering the expression of immune checkpoint molecules, such as PD-L1. …”
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Vertebral Artery Thrombosis in Chronic Idiopathic Thrombocytopenic Purpura by Zakaria Hindi, Nirmal Onteddu, Christopher A. Ching, Abdallah A. Khaled

“…While usage of antiplatelet therapy in such patients is debated, immunosuppression therapy has been the mainstay treatment in all published cases.…”
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Oxford-AstraZeneca Coronavirus Disease-2019 Vaccine-Induced Immune Thrombocytopenia on Day Two by Azhar Kareem Razzaq, Ameer Al-Jasim

“…ITP is treated with immunosuppression. Case Presentation. A 26-year-old Iraqi male laboratory analyst with an unremarkable medical history presented with severe thrombocytopenia 2 days after receiving the Oxford-AstraZeneca coronavirus disease-2019 vaccine. …”
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ACSL4 promotes the formation of the proliferative subtype in hepatoblastoma by Wei Dang, Qin Li, Xiaoying Wang

“…Among them, the proliferative subtype, characterized by enhanced proliferative capacity, poor prognosis, and an immunosuppressive tumor microenvironment, was particularly notable. …”
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Pancreatitis in systemic lupus erythematosus: Clinical characterization and outcome analysis in concurrent pancreatitis and lupus by Sheba Charles, Benzeeta Pinto, Vineeta Shobha

“…All our patients were treated with high-dose steroids and other immunosuppression as indicated for concomitant disease activity. …”
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Potential Application of Tregitopes as Immunomodulating Agents in Multiple Sclerosis by Wassim Elyaman, Samia J. Khoury, David W. Scott, Anne S. De Groot

“…Tregitopes expand Treg cells and induce “adaptive Tregs” resulting in immunosuppression and, therefore, are being considered as a potential therapy for autoimmune diseases. …”
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Ocular manifestations of COVID-19 by Sandra Saray Quignón Santana, Osbel Alfonso Sánchez, Sandra Alfonso Quignón, Talía Alfonso Quignón

“…In the recovery stage, ocular findings associated with systemic immunosuppression, vasculitic and thromboembolic processes are presented. …”
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Listeria Rhombencephalitis Complicating Anti-TNF Treatment during an Acute Flare of Crohn’s Colitis by L. Stratton, G. R. Caddy

“…Patients with Crohn’s disease often require the use of immunosuppressant drugs to control disease activity. Such medication includes steroids, azathioprine, and biologic therapy. …”
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Granulocytic Sarcoma by AML M4eo (inv16) after Allogeneic Stem Cell Transplantation without Bone Marrow Involvement by Stephan Zaenker, Stefan Schweyer, Justin Hasenkamp, Lorenz Truemper, Gerald Wulf

“…The patient underwent the withdrawal of immunosuppression, hysterectomy, and local irradiation at first relapse, as well as systemic chemotherapy and donor lymphocyte infusions at second recurrence, inducing a second and third complete remission, respectively. …”
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Vascular cytoprotection, autoimmune disease, and premature atherosclerosis by Justin C Mason

“…Identification of safe therapeutic approaches that combine the targeted immunosuppression required, along with comprehensive vascular protection to control the primary disease and prevent secondary complications over the longer term, remains the ultimate challenge.…”
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Disseminated Necrotizing Leukoencephalopathy Complicating Septic Shock in an Immunocompetent Patient by Pedro Gaspar-da-Costa, Sofia Reimão, Sandra Braz, João Meneses Santos, Rui M. M. Victorino

“…DNL was initially thought to be exclusively associated with immunosuppression conditions but it has been recently described in immunocompetent patients in septic shock. …”
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An Immunomodulatory Device Improves Insulin Resistance in Obese Porcine Model of Metabolic Syndrome by Angela J. Westover, Kimberly A. Johnston, Deborah A. Buffington, H. David Humes

“…Specific approaches targeting monocytes/ATM may improve insulin resistance without the adverse side effects of generalized immunosuppression. In this regard, a biomimetic membrane leukocyte processing device, called the selective cytopheretic device (SCD), was evaluated in an Ossabaw miniature swine model of insulin resistance with metabolic syndrome. …”
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IAPSM’s Position Paper on Pneumococcal Vaccine (PCV) for Adult Immunization in India by Chythra R. Rao, Veena G. Kamath, Anuradha Nadda, Swayam P. Parida, Nikita Sharma, Kapil Goel, Ranjitha S. Shetty, Madhur Verma, Arvind Kumar Singh, Abhisek Mishra, Swosti Kiran, Lalit Sankhe, Madhu Gupta

“…Pneumococcal vaccination is suggested for people aged 19–64 years with immunosuppression, chronic cardiac, lung and hepatic disease, impaired splenic function, uncontrolled diabetes mellitus, current smokers, and those abusing alcohol. …”
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Pneumocystis jirovecii Pneumonia in a HIV-Infected Patient with a CD4 Count Greater Than 400 Cells/μL and Atovaquone Prophylaxis by Abigayle Sullivan, Theresa Lanham, Ronald Krol, Shilla Zachariah

“…This case is a rare example of PCP in a patient with a normal CD4 count (>487 cells/μL) and a low viral load (<20 copies/mL) despite PCP prophylactic antibiotics in the setting of recent iatrogenic immunosuppression.…”
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A Rare Case of Suppurative Aspergillosis of the Thyroid by Nikhil Dinaker Thada, Sampath Chandra Prasad, Bhasker Alva, Monika Pokharel, Kishore Chandra Prasad

“…Fungal infections of the thyroid usually occur in immunocompromised patients with hematological malignancies, recipients of bone marrow and solid organ allografts on immunosuppression, and patients with AIDS. A 65-year-old male presented with swelling in the front of the neck for 2 years. …”
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Clostridium septicum Gas Gangrene in Colon Cancer: Importance of Early Diagnosis by Sowmya Nanjappa, Sweta Shah, Smitha Pabbathi

“…Clostridium septicum is a rare subgroup known to cause atraumatic myonecrosis and is associated with colonic malignancy or immunosuppression. It is a Gram-positive, anaerobic, spore-forming bacillus found in the gastrointestinal tract and can lead to direct, spontaneous infections of the bowel and peritoneal cavity. …”
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Binary and quaternary mixtures of perfluoroalkyl substances (PFAS) differentially affect the immune response to influenza A virus infection by Christina M. Post, Carrie McDonough, B. Paige Lawrence

“…PFAS often co-occur as mixtures in the environment, however, few studies have examined immunosuppression of PFAS mixtures or determined whether PFAS exposure affects immune function in the context of infection. …”
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Prognostic significance of ımmunhistochemical axl expression in pancreas ductal adenocarcinomas by Ozden Oz, Asuman Argon, Tulu Ayata Kebat, Ozlem Ozdemir, Savas Yakan

“…Tyrosine kinase receptors (TKRs) are responsible for cell plasticity, chemoresistance, immunosuppression and metastasis potential. Axl is a receptor of the TKR family, and it has come to the fore in cancer treatment in the last decade. …”
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Early Posttransplant Isolated v1 Lesion Does Not Need to Be Treated and Does Not Lead to Increased Fibrosis by Irfan Moinuddin, Bijin Thajudeen, Amy Sussman, Machaiah Madhrira, Erika Bracamonte, Mordecai Popovtzer, Pradeep V. Kadambi

“…However, we chose not to augment immunosuppression. The patient’s kidney allograft function improved over time with close monitoring. …”
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