First Results from the JWST Early Release Science Program Q3D: The Fast Outflow in a Red Quasar at z = 0.44 by Weizhe Liu, Sylvain Veilleux, Swetha Sankar, David S. N. Rupke, Nadia L. Zakamska, Dominika Wylezalek, Andrey Vayner, Caroline Bertemes, Yuzo Ishikawa, Yu-Ching Chen, Jenny E. Greene, Timothy Heckman, Guilin Liu, Hsiao-Wen Chen, Dieter Lutz, Sean D. Johnson, Nicole P. H. Nesvadba, Patrick Ogle, Nadiia Diachenko, Andy D. Goulding, Kevin N. Hainline, Fred Hamann, Hui Xian Grace Lim, Nora Lützgendorf, Vincenzo Mainieri, Ryan McCrory, Grey Murphree, Lu Shen, Eckhard Sturm, Lillian Whitesell

“…The local instantaneous outflow rates generally decrease radially. We infer that the quasar is powerful enough to drive the outflow, while stellar processes cannot be overlooked as a contributing energy source. …”
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Dramatic and Cinematic Potentials of the Fifth Dome in Nizami's Haft Peykar by Heydar Ali Dahmarde, Hojat Raeisi

“…Virtual space resources also proved invaluable in supplementing the findings. Subsequently, we classified and analyzed these notes to develop a systematic framework for the research. …”
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First Mid-infrared Detection and Modeling of a Flare from Sgr A* by Sebastiano D. von Fellenberg, Tamojeet Roychowdhury, Joseph M. Michail, Zach Sumners, Grace Sanger-Johnson, Giovanni G. Fazio, Daryl Haggard, Joseph L. Hora, Alexander Philippov, Bart Ripperda, Howard A. Smith, S. P. Willner, Gunther Witzel, Shuo Zhang, Eric E. Becklin, Geoffrey C. Bower, Sunil Chandra, Tuan Do, Macarena Garcia Marin, Mark A. Gurwell, Nicole M. Ford, Kazuhiro Hada, Sera Markoff, Mark R. Morris, Joey Neilsen, Nadeen B. Sabha, Braden Seefeldt-Gail

“…The MIRI instrument on JWST has changed that, and we report the first MIR detection of Sgr A*. The detection was during a flare that lasted about 40 minutes, a duration similar to NIR and X-ray flares, and the source's spectral index steepened as the flare ended. …”
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Long-term outcomes after AKI in hospitalized patients with COVID-19 by Bernardo Marques da Silva, Joana Gameiro, Joana Lei Teixeira, Cláudia Costa, Carolina Branco, João Oliveira, João Bernardo, Filipe Marques, José Agapito Fonseca, José António Lopes

“…Introduction and objectives: Acute kidney injury (AKI) is frequent in hospitalized patients and contributes to adverse short- and long-term outcomes. We aimed to evaluate the association of AKI and long-term adverse renal events and mortality in a cohort of patients hospitalized with COVID-19. …”
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Comparison of objectively measured and estimated cardiorespiratory fitness to predict all-cause and cardiovascular disease mortality in adults: A systematic review and meta-analysi... by Ben Singh, Cristina Cadenas-Sanchez, Bruno G.G. da Costa, José Castro-Piñero, Jean-Philippe Chaput, Magdalena Cuenca-García, Carol Maher, Nuria Marín-Jiménez, Ryan McGrath, Pablo Molina-García, Jonathan Myers, Bethany Gower, Francisco B. Ortega, Justin J. Lang, Grant R. Tomkinson

“…Methods: Systematic searches were conducted in 9 databases (MEDLINE, SPORTDiscus, Embase, Scopus, PsycINFO, Web of Science, PubMed, CINAHL, and the Cochrane Library) up to April 11, 2024. We included full-text refereed cohort studies published in English that quantified the association (using risk estimates with 95% confidence intervals (95%CIs)) of objectively measured, exercise-estimated, and non-exercise-estimated CRF with all-cause and CVD mortality in adults. …”
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The paediatric liver transplant experience in Johannesburg, South Africa: A broad overview and update by K Kinandu, A Beeton, M Beretta, S Berkenfeld, L Brannigan, R Britz, D Demopoulos, L Doedens, M Duncan, P Gaylard, C Hajinicolaou, W Lowman, H Maher, T De Maayer, V Mudau, S Rambarran, M Reynders, F van der Schyff, B Ströbele, S Tager, E Wessels, J Fabian, J Loveland

“…This paper presents a broad overview and update of the unit’s 17-year experience.   Methods: We conducted a retrospective review of all paediatric liver transplants performed in Johannesburg from 1 January 2005 to 31 December 2021 with a minimum one-year follow-up. …”
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Disease activity in patients with idiopathic inflammatory myopathy according to time since diagnosis and positivity to antisynthetase autoantibodies: data from the Myo-Spain regist... by Tatiana Cobo-Ibáñez, Ivan Castellví, Ana Pros, Marta Domínguez-Álvaro, Laura Nuño-Nuño, Julia Martínez-Barrio, Vega Jovaní, Fredeswinda Romero-Bueno, Esther Ruiz-Lucea, Eva Tomero, Ernesto Trallero-Araguás, Javier Narváez, Jordi Camins-Fàbregas, Alberto Ruiz-Román, Jesús Loarce-Martos, Susana Holgado-Pérez, V Miguel Flores-Rodríguez, Francisca Sivera, Carolina Merino-Argumanez, Antonio Juan-Mas, Irene Altabás-González, María Martín-López, Joaquín María Belzunegui-Otano, Carmen Carrasco-Cubero, Mercedes Freire-González, Iñigo Rúa-Figueroa, Nuria Lozano-Rivas, Julio David Suarez-Cuba, Olga Martínez, Rafaela Ortega-Castro, Patricia Alcocer, Alejandro Gómez-Gómez, Olga Sánchez-Pernaute, José Luis Tandaipan, Irene Carrión-Barberà, Chamaida Plasencia-Rodríguez, Oihane Ibarguengoitia-Barrena, Paola Vidal-Montal, Vera Ortiz-Santamaria, Noemi Garrido-Puñal, Anne Riveros, Esmeralda Delgado-Frías, Juan Miguel López-Gómez, Carmen Barbadillo, José María Pego-Reigosa, Beatriz E. Joven-Ibáñez, Jesús Alejandro Valero-Jaimes, Elena Naveda, Ana Isabel Turrión-Nieves, Daniel Seoane-Mato, Francisco Javier Prado-Galbarro, M Ángeles Puche-Larrubia

“…Other measures of activity, damage, and quality of life included patient global disease activity, MYOACT muscular, creatine phosphokinase, Health Assessment Questionnaire, physician and patient global damage, global damage of the Myositis Damage Index, and the 12-item Short-Form Health Survey (SF-12). We analyzed associations using a multivariate generalized linear model and a simple linear regression model. …”
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Model organisms for investigating the functional involvement of NRF2 in non-communicable diseases by Ana I. Rojo, Brigitta Buttari, Susana Cadenas, Ana Rita Carlos, Antonio Cuadrado, Ana Sofia Falcão, Manuela G. López, Milen I. Georgiev, Anna Grochot-Przeczek, Sentiljana Gumeni, José Jimenez-Villegas, Jarosław Olav Horbanczuk, Ozlen Konu, Isabel Lastres-Becker, Anna-Liisa Levonen, Viktorija Maksimova, Charalambos Michaeloudes, Liliya V. Mihaylova, Michel Edwar Mickael, Irina Milisav, Biljana Miova, Patricia Rada, Marlene Santos, Miguel C. Seabra, Dubravka Svob Strac, Sandra Tenreiro, Ioannis P. Trougakos, Albena T. Dinkova-Kostova

“…This review is a comprehensive summary of the most commonly used model organisms of NCDs in which NRF2 has been genetically or pharmacologically modulated, paving the way for drug development to combat NCDs. We discuss the validity and use of these models and identify future challenges.…”
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Factors Contributing to Retention in Care and Treatment Adherence Among People Living With HIV Returning to Care in South-Eastern Tanzania: A Qualitative Study by Matimbwa H, Lolo SA, Matoy LS, Ndaki R, Ngahyoma S, Mollel HA, Luoga E, Vanobberghen F, Vianney JM, Idindili B, Weisser M

“…This study explored factors related to dropout, return, retention in care, and treatment adherence among PLHIV returning to care after missing clinical visits.Methods: We conducted an exploratory study using a phenomenological approach in rural South-eastern Tanzania, from July to October 2023. …”
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Novel carbon dots with dual Modulatory effects on the bone marrow and spleen as a potential therapeutic candidate for treating spinal cord injury by Junjin Li, Hongda Wang, Yuanquan Li, Chunzhen Wang, Haiwen Feng, Yilin Pang, Jie Ren, Chuanhao Li, Erke Gao, Dejing Zhang, Dunxu Hu, Pengtian Zhao, Han Ding, Baoyou Fan, Tao Zhang, Xiaomeng Song, Zhijian Wei, Guangzhi Ning, Yong-Qiang Li, Shiqing Feng

“…However, current treatments for spinal cord injuries overlook interventions targeting peripheral immune organs and tissues, highlighting the need to develop novel drugs capable of effectively regulating peripheral immunity and treating spinal cord injuries. In this study, we designed, synthesized, and characterized novel Ejiao carbon dots (EJCDs) that inhibit myeloid cell proliferation and peripheral migration by promoting HSC self-renewal, and distinct differentiation into erythroid progenitors in vitro and in vivo. …”
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Translational and clinical comparison of whole genome and transcriptome to panel sequencing in precision oncology by Irina A. Kerle, Thomas Gross, Anja Kögler, Jonas S. Arnold, Maximilian Werner, Jan-Niklas Eckardt, Elena E. Möhrmann, Marie Arlt, Barbara Hutter, Jennifer Hüllein, Daniela Richter, Martin M. K. Schneider, Mario Hlevnjak, Lino Möhrmann, Dorothea Hanf, Christoph E. Heilig, Simon Kreutzfeldt, Maria-Veronica Teleanu, Evelin Schröck, Daniel Hübschmann, Peter Horak, Christoph Heining, Stefan Fröhling, Hanno Glimm

“…Abstract Precision oncology offers new cancer treatment options, yet sequencing methods vary in type and scope. In this study, we compared whole-exome/whole-genome (WES/WGS) and transcriptome sequencing (TS) with broad panel sequencing by resequencing the same tumor DNA and RNA as well as normal tissue DNA for germline assessment, from 20 patients with rare or advanced tumors, who were originally sequenced by WES/WGS ± TS within the DKFZ/NCT/DKTK MASTER program from 2015 to 2020. …”
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Clinical and genetic drivers of oligo-metastatic disease in colon cancer by Alessandro Ottaiano, Mariachiara Santorsola, Roberto Sirica, Annabella Di Mauro, Antonella Di Carlo, Monica Ianniello, Francesco Sabbatino, Rosa Castiello, Francesca Del Peschio, Marco Cascella, Francesco Perri, Maurizio Capuozzo, Nicola Martucci, Edoardo Mercadante, Valentina Borzillo, Rossella Di Franco, Francesco Izzo, Vincenza Granata, Carmine Picone, Antonella Petrillo, Massimiliano Berretta, Salvatore Stilo, Luca Tarotto, Anna Chiara Carratù, Gerardo Ferrara, Madhura Tathode, Alessia Maria Cossu, Marco Bocchetti, Michele Caraglia, Guglielmo Nasti, Giovanni Savarese

“…Additionally, by integrating data from public datasets and our case study, we hypothesize that some gene alterations (i.e.: BRAF, SMAD4, RAF1, and mTOR) may prevent OMD occurrence. …”
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Kilka uwag o pijarskich muzykach z XVII i XVIII wieku: Stachowicz, Pasternacki, Szczawnicki, Caspar by Ryszard Mączyński

“…Artykuł niniejszy sprowokowany został lekturą tychże książek, lecz nie pretenduje ani do miana recenzji, ani do miana polemiki, ma natomiast na celu baczniejsze przyjrzenie się kilku szczegółowym zagadnieniom, które pojawiły się we wspomnianych pracach. Wynika to z poczucia, iż postać kompozytora Damiana Stachowicza (1658–99) jest tak doniosła w dziejach muzyki nie tylko polskiej, lecz i europejskiej, a kolekcja muzykaliów podolinieckich tak unikalna, choćby jedynie w odniesieniu do zakonu pijarskiego, że każda kwestia, nawet z pozoru drobna, jest godna rozważenia, niekiedy sprostowania, niekiedy uzupełnienia. …”
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Association between plasma perfluoroalkyl substances and high-grade serous ovarian cancer overall survival: A nested case-control study by Wei-Yi Xing, Fang-Hua Liu, Dong-Dong Wang, Jia-Ming Liu, Wen-Rui Zheng, Jia-Xin Liu, Lang Wu, Yue-Yang Zhao, He-Li Xu, Yi-Zi Li, Yi-Fan Wei, Dong-Hui Huang, Xiao-Ying Li, Song Gao, Qi-Peng Ma, Ting-Ting Gong, Qi-Jun Wu

“…Objective: To explore the association between plasma PFASs and high-grade serous ovarian cancer (HGSOC) overall survival (OS) in the population who did not smoke. Methods: We conducted a nested case-control study within the Ovarian Cancer Follow-Up Study, matching 159 dead patients and 159 survival ones based on body mass index, sample date, and age at diagnosis. …”
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Contextual Vulnerability Should Guide Fair Subject Selection in Xenotransplantation Clinical Trials by Gianna Strand

“…“Allocating Organs to Cognitively Impaired Patients,” New England Journal of Medicine 376, no. 4 (2017): 299-301. [xii] “How We Match Organs,” United Network for Organ Sharing, accessed April 18, 2022, https://unos.org/transplant/how-we-match-organs/. …”
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Blood and Iron: The Rise and Fall of the German Empire 1871 – 1918 by Arzu Melek Ozgumus

“…She provides a clear picture of the nation-building process that lead to small German states into Germany we know today. Details she focused on, indeed, helps the reader to understand the German society, industry and economy today. …”
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Global, regional and national sodium intakes in 1990 and 2010: a systematic analysis of 24 h urinary sodium excretion and dietary surveys worldwide by J Lennert Veerman, Sarah Lewis, John Britton, Bruce Neal, Kathryn G Andrews, Goodarz Danaei, Majid Ezzati, Yanping Li, Yu Chen, Farshad Farzadfar, Jean-Michel Gaspoz, Idris Guessous, Lital Keinan-Boker, Paul Elliott, Carukshi Arambepola, Antonia Trichopoulou, Philippos Orfanos, Martin C Gulliford, Renata Micha, Dariush Mozaffarian, Wen-Harn Pan, Shoichiro Tsugane, Habibul Ahsan, Manami Inoue, Luz Maria Sanchez-Romero, Andrew Fogarty, Christos Pitsavos, Edward Giovannucci, Stefaan De Henauw, Stephen S Lim, Cho-il Kim, Inge Huybrechts, Didier Garriguet, Simón Barquera, Katia Castetbon, Neville Calleja, Peilin Shi, Hsing-Yi Chang, Yasuhiro Matsumura, Hubert Barennes, Guansheng Ma, Shahab Khatibzadeh, Saman Fahimi, John Powles, Morteza Abdollahi, Anahita Houshiar-rad, Eda Koksal, Sahar Zaghloul, Sirje Vaask, Ana Baylin, Simon Forsyth, Rosely Sichieri, Christian Haerpfer, Ian Brown, Demosthenes B Panagiotakos, Jacqui Webster, Androniki Naska, Dorothy Gauci, Rebecca E Engell, Tim E Byers, Stephanie Smith-Warner, Ibrahim Elmadfa, Mayuree Rao, Pamela A Abbott, Enrique O Abeyá Gilardon, Suad N Al-Hooti, Wulf Becker, Peter Bjerregaard, Lesley T Bourne, Mario V Capanzana, Melanie J Cowan, Dulitha N Fernando, Regina M Fisberg, Brahmam NV Ginnela, Wilbur Hadden, Daniel J Hoffman, Nahla C Hwalla, Hajah Masni Ibrahim, Maria D Jackson, Lars Johansson, Hae-Jeung Lee, Chan Mei Fen, Gert BM Mensink, Rafael A Monge-Rojas, Balakrishna Nagalla, Marga C Ocke, Maciej Oltarzewski, Marja-Leena Ovaskainen, Gulden Ayla Pekcan, Stefka Petrova, Noppawan Piaseu, Leanne M Riley, Rusidah BT Selamat, Chansimaly Simmala, Laufey Steingrimsdottir, Gillian Swan, Lucjan Szponar, Heli Tapanainen, Robert Templeton, Anastasia Thanopoulou, Holmfridur Thorgeirsdóttir, Inga Thorsdottir, Aida Turrini, Nowak Verena, Anna Waskiewicz, Gábor Zajkás, Shadi Kalantarian, Pattra Wirojratana, Mary Anne Land, Tricia McKeever, Mohannad Abed Alfattah Al Nsour, Medical Science, Heléne Enghardt Barbieri, Aida Filipovic Hadziomeragic, Nur Indrawaty Lipoeto, Stephen T. McGarvey, Abdulrahman Obaid. Musaiger, Luz Gladys. Posada, Elz˙bieta Halina. Sygnowska

“…Objectives To estimate global, regional (21 regions) and national (187 countries) sodium intakes in adults in 1990 and 2010.Design Bayesian hierarchical modelling using all identifiable primary sources.Data sources and eligibility We searched and obtained published and unpublished data from 142 surveys of 24 h urinary sodium and 103 of dietary sodium conducted between 1980 and 2010 across 66 countries. …”
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Management modes and effects analysis of strengthening the volunteer’s normalized nucleic acid sampling (加强志愿者常态化核酸采样的管理方法与效果) by HAN Chunying (韩春英), YOU Chenggang (尤诚刚), PAN Meili (潘美丽), JIANG Yuting (蒋玉婷), XU Yiwen (徐伊雯), LU Weijie (陆玮婕), XIA Hui (夏卉), CHEN Haiyan (陈海燕), HUANG Ying (黄莹), GU Yuanlu (顾元露), CHEN Huiying (陈慧颖), ZHANG Qi (张琪), LI Xu (李旭), WU Weina (吴维娜), SHEN Xiaojie (沈晓洁), ZHOU Yi (周毅), ZHANG Xian (张宪), LI Qin (李琴)

“…The volunteers were assigned to control group (n=300) and test group (n=300). WeChat group and self-made questionnaires were developed while the normalized nucleic acid sampling manuals were delivered. …”
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Dimorphos’s Material Properties and Estimates of Crater Size from the DART Impact by Angela M. Stickle, Kathryn M. Kumamoto, Dawn M. Graninger, Mallory E. DeCoster, Wendy K. Caldwell, Jason M. Pearl, J. Michael Owen, Olivier Barnouin, Gareth S. Collins, R. Terik Daly, Isabel Herreros, Jens Ormö, Jessica Sunshine, Carolyn M. Ernst, Toshi Hirabayashi, Simone Marchi, Laura Parro, Harrison Agrusa, Megan Bruck Syal, Nancy L. Chabot, Andy F. Cheng, Thomas M. Davison, Elisabetta Dotto, Eugene G. Fahenstock, Fabio Ferrari, Martin Jutzi, Alice Lucchetti, Robert Luther, Nilanjan Mitra, Maurizio Pajola, Sabina Raducan, KT Ramesh, Andrew S. Rivkin, Alessandro Rossi, Paul Sánchez, Stephen R. Schwartz, Stefania Soldini, Jordan K. Steckloff, Filippo Tusberti, Kai Wünnemann, Yun Zhang

“…Approach observations and those following the DART impact have provided crucial knowledge that narrows the parameter space relevant to modeling the impact into Dimorphos. Here we present the results of a suite of hydrocode simulations of the DART impact on Dimorphos. …”
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Macrophage-mimicking nanotherapy for attenuation of acute pancreatitis by Fengyu Shi, Akmal Ergashev, Zhenyan Pan, Hongwei Sun, Lingming Kong, Yuepeng Jin, Tan Zhang, Zhu Liu, Haonan Xie, Jinhui Wang, Huiping Li, Yi Wang, Lifei Zheng, Jianliang Shen, Andreas Herrmann, Gang Chen, Hongru Kong

“…To address this challenge, we herein demonstrate a surface masking strategy that involves coating the surface of selenylated Poria cocos polysaccharide nanoparticles with a layer of macrophage plasma membrane to circumvent MPS sequestration, thereby enhancing the therapeutic efficacy of selenylated Poria cocos polysaccharide nanoparticles. …”
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