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95301
Identifying joint association between body fat distribution with high blood pressure among 7 ∼ 17 years using the BKMR model: findings from a cross-sectional study in China
Published 2025-01-01“…Conclusions Fat distribution of various body parts have inconsistent roles and directions in their association with HBP risk in children of different sex and weight status. We recommend that children of different sexes and weight statuses be provided with body-part-specific exercise recommendations for optimal chronic disease prevention and control benefits.…”
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95302
Diversity and Complexity of CTXΦ and Pre-CTXΦ Families in <em>Vibrio cholerae</em> from Seventh Pandemic
Published 2024-09-01“…In this study, 21 <i>V. cholerae</i> strains, which were shown to carry the CTXΦ/pre-CTXΦ prophages as opposed to typical CTX<sup>ET</sup>Φ-RS1 structure, were selected from approximately 1000 strains with diverse genomes. We identified two CTXΦ members and six pre-CTXΦ members with distinct <i>rstR</i> alleles, revealing complex chromosomal DNA integration patterns and arrangements of different prophages in these strains. …”
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95303
Breastfeeding support as predictors of sustainable breastfeeding practices of nursing mothers with common mental disorders in tertiary hospital nurseries in Nigeria: a cross sectio...
Published 2024-12-01“…To assess mothers' mental health and breastfeeding support, we utilised the WHO self-reporting Questionnaire 20 and an adapted WHO/UNICEF ten-step breastfeeding support package. …”
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95304
Association between left ventricular reverse remodelling and the B-type natriuretic peptide–cGMP cascade after anterior acute myocardial infarction
Published 2025-01-01“…Background The role of cyclic guanosine 3′,5′-monophosphate (cGMP) after acute myocardial infarction (AMI) is not well understood despite its significance as a second messenger of natriuretic peptides (NPs) in cardiovascular disease. We investigated the association between the NP-cGMP cascade and left ventricular reverse remodelling (LVRR) in anterior AMI.Methods 67 patients with their first anterior AMI (median age, 64 years; male, 76%) underwent prospective evaluation of plasma concentrations of the molecular forms of A-type and B-type natriuretic peptide (BNP) and cGMP from immediately after primary percutaneous coronary intervention (PPCI) to 10 months post-AMI. …”
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95305
Pilot clinical trial of neoadjuvant toll-like receptor 7 agonist (Imiquimod) immunotherapy in early-stage oral squamous cell carcinoma
Published 2025-01-01“…BackgroundThere is no neoadjuvant immunotherapy for early-stage oral cancer patients. We report a single-arm, open-label, pilot clinical trial assessing the efficacy and safety of topical toll-like receptor-7 (TLR-7) agonist, imiquimod, utilized in a neoadjuvant setting in early-stage oral squamous cell carcinoma (OSCC).MethodsThe primary endpoint is reduction in tumor cell counts assessed by quantitative multiplex immunofluorescence and the immune-related pathologic response. …”
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95306
Maternal and neonatal complications of pregnant women with bipolar disorder: a systematic review and meta-analysisResearch in context
Published 2025-01-01“…These results can serve as a basis for the development of guidelines for the prevention and management of these complications. We need additional data from other countries, particularly from low-to-moderate income countries. …”
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95307
Providing digital human resource management model
Published 2024-11-01“…In explaining these results, we can mention the impact of the context and environment in which an organization plays a role, which is more important in relation to private sectors. …”
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95308
Sport participation as an educational tool and a means of promoting physical, mental, and social well-being
Published 2024-12-01“…Therefore, it is clear that we must rethink the educational model linked to sports practice to promote harmonious and healthy development for young people, ensuring inclusivity and enabling everyone to fully benefit from sports participation. …”
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95309
Exploring the potential of an oyster (Saccostrea mordax) in oligotrophic seas: Effects of starvation on physiological and molecular regulation
Published 2025-03-01“…Its dominant oyster species, Saccostrea mordax, remains unclear regarding starvation tolerance and underlying mechanisms. Here, we treated S. mordax with starvation for four months. …”
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95310
Ground-based Reconnaissance Observations of 21 Exoplanet Atmospheres with the Exoplanet Transmission Spectroscopy Imager
Published 2025-01-01“…This work also describes the various statistical tests performed on the data to evaluate the efficacy of the CMI method and the ETSI instrument in combination. We find that none of the eight comparisons of exoplanet atmospheres measured with ETSI and other observatories (including the Hubble Space Telescope) provide evidence that the spectra are statistically dissimilar. …”
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95311
Surgical interventions for spontaneous supratentorial intracerebral haemorrhage: a systematic review and network meta-analysisResearch in context
Published 2025-01-01“…Methods: In this systematic review and network meta-analysis, we searched PubMed, Cochrane Central Register of Controlled Trials, Embase, and ClinicalTrials.gov from inception to June 16, 2024. …”
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95312
The time has come for revising the rules of clozapine blood monitoring in Europe. A joint expert statement from the European Clozapine Task Force
Published 2025-01-01“…We believe the time has come for relaxing the rules without increasing the risks for people using clozapine in Europe.…”
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95313
Large range sizes link fast life histories with high species richness across wet tropical tree floras
Published 2025-02-01“…For Amazonian genera, we also explore whether traits are related to species richness via variation among genera in mean species-level range size. …”
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95314
Multi-cancer early detection tests for general population screening: a systematic literature review
Published 2025-01-01“…We thoroughly searched for relevant studies and found over 8000 records. …”
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95315
Same data, different analysts: variation in effect sizes due to analytical decisions in ecology and evolutionary biology
Published 2025-02-01“…However, there were also several striking outliers in the Eucalyptus dataset, with effects far from zero. For both datasets, we found substantial variation in the variable selection and random effects structures among analyses, as well as in the ratings of the analytical methods by peer reviewers, but we found no strong relationship between any of these and deviation from the meta-analytic mean. …”
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95316
Effects of Climatic Conditions and Agronomic Practices on Health, Tuber Yield, and Mineral Composition of Two Contrasting Potato Varieties Developed for High and Low Input Producti...
Published 2024-12-01“…To test this hypothesis, we used an existing long-term factorial field experiment (the NEFG trials) to assess the effect of crop management practices (rotation design, fertilization regime, and crop protection methods) used in conventional and organic farming systems on crop health, tuber yield, and mineral composition parameters in two potato varieties, Santé and Sarpo mira, that were developed in breeding programs for high and low-input farming systems, respectively. …”
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95317
Comparative Study of the Chemical Composition Disparities Between Fast-twitch and Slow-twitch Muscles in Marine Teleost Fishes
Published 2025-02-01“…To comprehend the chemical composition characteristics and elucidate the material basis for the functional differences between fast-twitch and slow-twitch muscles, this study used biochemical analysis to determine the chemical components of the two muscle types in Pseudocaranx dentex and Liza haematocheila. We integrated data from the literature on tuna, including Thunnus tonggol, T. albacares, Auxis rochei, A. thazard, Euthynnus affinis, and Katsuwonus pelamisi. …”
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95318
Evaluating small coronary stents with dual-source photon-counting computed tomography: effect of different scan modes on image quality and performance in a phantom
Published 2025-01-01“…METHODS: Utilizing a phantom setup mimicking the average patient’s water-equivalent diameter, we examined six distinct coronary stents inflated in a silicon tube, with stent sizes ranging from 2.0 to 3.5 mm, applying four different CT acquisition modes of a dual-source PCD-CT scanner: “high-pitch,” “sequential,” “spiral” (each with collimation of 144 × 0.4 mm and full spectral information), and “ultra-high-resolution (UHR)” (collimation of 120 × 0.2 mm and no spectral information). …”
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95319
Germline Human Leukocyte Antigen Status is Associated With Immunotherapy-Induced Pneumonitis and Treatment Response in Patients With Non–Small Cell Lung Cancer With High Programmed...
Published 2025-01-01“…Introduction: The germline human leukocyte antigen (HLA) status has been found to be associated with immunotherapy outcomes in patients with NSCLC, but its correlation to immunotherapy-induced pneumonitis and prognostic impact in the Asian population remains largely unknown. Methods: We evaluated the HLA genotype of the germline and available tumor samples in 42 patients with programmed death-ligand 1 expression of 50% or higher undergoing pembrolizumab immunotherapy. …”
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95320
Is maternal diabetes during pregnancy associated with neurodevelopmental, cognitive and behavioural outcomes in children? Insights from individual participant data meta-analysis in...
Published 2025-01-01“…However, the results of individual cohort studies have been inconsistent. We aimed to investigate the association between maternal diabetes before pregnancy and gestational diabetes mellitus (GDM) with neurodevelopmental, cognitive and behavioural outcomes in children. …”
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