Early bactericidal activity of sitafloxacin against pulmonary tuberculosis by Lihui Nie, Jing Tong, Guihui Wu, Juan Du, Yuanyuan Shang, Yufeng Wang, Zhangjun Wu, Yuanhong Xu, Yi Ren, Youyi Rao, Yu Pang, Mengqiu Gao

“…However, its efficacy in patients with primary-sensitive tuberculosis is unclear. We investigated the early bactericidal activity of sitafloxacin in primary susceptible tuberculosis. …”
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The Edge Odd Graceful Labeling of Water Wheel Graphs by Mohammed Aljohani, Salama Nagy Daoud

“…The main objective of this manuscript is to introduce new classes of planar graphs, namely water wheel graphs, <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mi>W</mi><msub><mi>W</mi><mi>n</mi></msub></mrow></semantics></math></inline-formula>; triangulated water wheel graphs, <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mi>T</mi><msub><mi>W</mi><mi>n</mi></msub></mrow></semantics></math></inline-formula>; closed water wheel graphs, <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mi>C</mi><msub><mi>W</mi><mi>n</mi></msub></mrow></semantics></math></inline-formula>; and closed triangulated water wheel graphs, <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mi>C</mi><msub><mi>T</mi><mi>n</mi></msub></mrow></semantics></math></inline-formula>. Furthermore, we specify conditions for these graphs to allow for edge odd graceful labelings.…”
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Analysis of stomatal characteristics of maize hybrids and their parental inbred lines during critical reproductive periods by Changyu Zhang, Changyu Zhang, Yu Jin, Yu Jin, Jinglu Wang, Jinglu Wang, Ying Zhang, Ying Zhang, Yanxin Zhao, Xianju Lu, Xianju Lu, Wei Song, Xinyu Guo, Xinyu Guo

“…This study employed Jingnongke 728 and its parental inbred to capture stomatal images from various leaf positions and abaxial surfaces during key reproductive stages using rapid scanning electron microscopy. We uesd a target detection and image segmentation approach based on YOLOv5s and Unet to efficiently obtain 11 phenotypic traits encompassing stomatal count, shape, and distribution. …”
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Splenic artery aneurysms – a systematic review of the literature by Marta Machado, Andreia Coelho, João Peixoto, Luís Fernandes, Roberto Boal, Francisco Basílio, Patrícia Carvalho, Beatriz Guimarães, Pedro Brandão, Alexandra Canedo

“…Due to their rarity, there is a lack of data, so we aimed to perform a systematic review of available SAA data. …”
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A Model for Bank Management Performance Appraisal with the Advanced Technologies Approach (Meta-Synthesis Method) by Ehsan Kiani Ghalehno, Habibollah Salarzehi, Bahareh Naseri, Abdolali Keshtegar

“…These emerging dynamic technologies are dangerous even if they have positive effects on financial institutions and bank managers cannot protect their information assets against any attack on information security (Okoht , 2020).Case studyAssessing the performance of managers in branches of melli Bank of Sistan and Baluchistan province.Materials and MethodsWe have great development in this space using IR 0. 4 as setting new records or applying for personal credits in advanced banks enables buyers to do banking operations using available strategic tools. …”
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ERRα promotes glycolytic metabolism and targets the NLRP3/caspase-1/GSDMD pathway to regulate pyroptosis in endometrial cancer by Pingping Su, Xiaodan Mao, Jincheng Ma, Lixiang Huang, Lirui Yu, Shuting Tang, Mingzhi Zhuang, Zhonglei Lu, Kelvin Stefan Osafo, Yuan Ren, Xinrui Wang, Xite Lin, Leyi Huang, Xiaoli Huang, Elena Ioana Braicu, Jalid Sehouli, Pengming Sun

“…Estrogen-related receptor alpha (ERRα) is a central regulator of cellular energy metabolism associated with poor cancer prognosis. Herein, we refine the oncogenic role of ERRα in the pyroptosis pathway and glycolytic metabolism. …”
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Learning environment as a predictor for medical students’ empathy: a multicenter cross-sectional study from 12 medical schools in China by Runzhi Huang, Jiaying Shi, Yifan Liu, Shuyuan Xian, Wei Zhang, Yuntao Yao, Xinru Wu, Yuanan Li, Haoyu Zhang, Bingnan Lu, Jiajie Zhou, Yibin Zhou, Min Lin, Xiaonan Wang, Xin Liu, Yue Wang, Wenfang Chen, Chongyou Zhang, Erbin Du, Qing Lin, Zongqiang Huang, Yu Chen, Jie Zhang, Jun Liu, Xihui Chen, Xiuwu Pan, Xingang Cui, Shizhao Ji, Huabin Yin

“…Empathy appeared to be affected by the learning environment (LE), which could be a potential contributor. We conducted a cross-sectional study to investigate the association between LE and empathy. …”
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Deep Searches for Radio Pulsations and Bursts from Four Magnetar and a Magnetar-like Pulsar with FAST by Juntao Bai, Na Wang, Shi Dai, Shuangqiang Wang, Jianping Yuan, Wenming Yan, Lunhua Shang, Xin Xu, Shijun Dang, Zhen Zhang

“…We report on radio observations of four magnetars SGR 0501+4516, Swift 1834.9–0846, 1E 1841–045, SGR 1900+14, and a magnetar-like pulsar PSR J1846–0258 with the Five-hundred-meter Aperture Spherical radio Telescope at 1250 MHz. …”
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POPULATION STRUCTURE OF LEAF PATHOGENS OF COMMON SPRING WHEAT IN THE WEST ASIAN REGIONS OF RUSSIA AND NORTH KAZAKHSTAN IN 2017 by E. I. Gultyaeva, N. M. Kovalenko, V. P. Shamanin, V. A. Tyunin, E. R. Shreyder, E. L. Shaydayuk, А. I. Morgunov

“…The prevalence of isolates virulent on ТсLr2a, ТсLr2b, ТсLr2c, ТсLr11, ТсLr15, ТсLr16, ТсLr20 and ТсLr26 was higher in the Omsk and the North Kazakhstani population, while virulence to ТсLr9 was higher in Chelyabinsk. Using 20 TcLr-lines, we identified 27 virulent phenotypes of P. triticina: 12 in the Omsk, 19 in the Chelyabinsk and 8 in the Kazakhstani population. …”
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Annexin A8 deficiency delays atherosclerosis progression by Carmen Gutiérrez‐Muñoz, Rafael Blázquez‐Serra, Irene San Sebastian‐Jaraba, Sandra Sanz‐Andrea, Maria J. Fernández‐Gómez, Gonzalo Nuñez‐Moreno, Pablo Mínguez, Joan Carles Escolá‐Gil, Paula Nogales, Veronique Ollivier, Jose L. Martín‐Ventura, Benoit Ho‐Tin Noe, Ursula Rescher, Nerea Méndez‐Barbero, Luis M. Blanco‐Colio

“…By studying the aortic transcriptome of atherosclerosis‐prone apolipoprotein E (ApoE−/−) mice, we aimed to identify novel players in the progression of atherosclerosis. …”
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Visceral adipose tissue area and proportion provide distinct reflections of cardiometabolic outcomes in weight loss; pooled analysis of MRI-assessed CENTRAL and DIRECT PLUS dietary... by Hadar Klein, Hila Zelicha, Anat Yaskolka Meir, Ehud Rinott, Gal Tsaban, Alon Kaplan, Yoash Chassidim, Yftach Gepner, Matthias Blüher, Uta Ceglarek, Berend Isermann, Michael Stumvoll, Ilan Shelef, Lu Qi, Jun Li, Frank B. Hu, Meir J. Stampfer, Iris Shai

“…However, it is unclear to what extent VAT area (VATcm2) and its proportion of total abdominal adipose tissue (VAT%) are distinguished in predicting cardiometabolic status and clinical outcomes during weight loss. Methods We integrated magnetic resonance imaging (MRI) measurements of VAT, deep-SAT, and superficial-SAT from two 18-month lifestyle weight loss clinical trials, CENTRAL and DIRECT PLUS (n = 572). …”
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Prophylactic phage administration provides a time window for delayed treatment of vancomycin-resistant Enterococcus faecalis in a murine bacteremia model by Wei-Xiao Wang, Jiao-Yang Yu, Xiu-Zhen Chen, Xiu-Zhen Chen, Shi-Yong Fu, Hui Li, Peng-Cheng Yi, Yun-Yao Ren, Shuang-Lin Gu, Jing-Han Gao, Jing Fan, Yan-Mei Sun, Jie Feng, Shi-Wei Wang, Wei Chen, Wei Chen

“…The impact of phage therapy on gut microbiota was examined through 16S rDNA gene sequencing.ResultsWe isolated and characterized a novel lytic phage, vB_EfaS-1017, specific to vancomycin-resistant E. faecalis. …”
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Unravelling nonclassical beam damage mechanisms in metal-organic frameworks by low-dose electron microscopy by Xiaoqiu Xu, Liwei Xia, Changlin Zheng, Yikuan Liu, Dongyang Yu, Jingjing Li, Shigui Zhong, Cuiyu Li, Huijun Song, Yunzhou Liu, Tulai Sun, Yonghe Li, Yu Han, Jia Zhao, Qiang Lin, Xiaonian Li, Yihan Zhu

“…In light of these developments, the exploration of more precise and specific beam damage mechanisms, along with the development of associated descriptive models, has expanded the theoretical framework of radiation damage beyond classical mechanisms. We unravel, in this work, the nonclassical beam damage mechanisms of an open-framework material, i.e. …”
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Analysis of Genetic Variation in CD40 and CD40L: Relationship with mRNA Relative Expression and Soluble Proteins in Acute Coronary Syndrome by D. E. Martínez-Fernández, J. R. Padilla-Gutiérrez, F. Casillas-Muñoz, Emmanuel Valdés-Alvarado, Brenda Parra-Reyna, Maricela Aceves-Ramírez, J. F. Muñoz-Valle, U. Zalapa Flores, J. C. Chávez Herrera, Y. Valle

“…Soluble protein isoforms were measured by enzyme-linked immunosorbent assay. We did not find evidence of association between CD40 (rs1883832, rs4810485, and rs11086998) and CD40L (rs3092952 and rs3092920) genetic variants and susceptibility to ACS, although rs1883832 and rs4810485 were significantly associated with high sCD40 plasma levels. …”
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Golgi-restored vesicular replenishment retards bone aging and empowers aging bone regeneration by Peisheng Liu, Hao Guo, Xiaoyao Huang, Anqi Liu, Ting Zhu, Chenxi Zheng, Fei Fu, Kaichao Zhang, Shijie Li, Xinyan Luo, Jiongyi Tian, Yan Jin, Kun Xuan, Bingdong Sui

“…However, the mechanistic understandings of stem cell senescence and the potential strategies to counteract it remain elusive. Here, we reveal that the aging bone microenvironment impairs the Golgi apparatus thus diminishing mesenchymal stem cell (MSC) function and regeneration. …”
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Interaction study of the effects of environmental exposure and gene polymorphisms of inflammatory and immune-active factors on chronic obstructive pulmonary disease by Rui Wang, Yuanyuan Li, Yuting Jiang, Xiaona Liu, Hongqi Feng, Zhe Jiao, Bingyun Li, Chang Liu, Yuncheng Shen, Fang Chu, Chenpeng Zhu, Dianjun Sun, Wei Zhang

“…Single nucleotide polymorphism (SNP) in the human genome may influence the risk of developing COPD and the response to treatment. We assessed the effects of gene polymorphism of inflammatory and immune-active factors and gene-environment interaction on risk of COPD in middle-aged and older Chinese individuals. …”
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Clinical implications of proximal tubular multicilia in glomerular diseases by Bohye Kim, Boram Weon, Evonne Kim, Sohee Park, Wencheng Jin, Nayeon Shin, Yun Kyu Oh, Chun Soo Lim, Jung Pyo Lee, Obin Kwon, Jeonghwan Lee

“…Introduction: Multiciliated cells (MCCs) have been identified in the proximal tubules of patients with kidney disease; however, their clinical significance is unknown. We aimed to investigate whether MCCs are associated with clinical outcomes in patients with glomerular diseases. …”
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Longitudinal Survey of Astrovirus infection in different bat species in Zimbabwe: Evidence of high genetic Astrovirus diversity by Chidoti, Vimbiso, De Nys, Hélène, Abdi, Malika, Mashura, Getrude, Pinarello, Valérie, Chiweshe, Ngoni, Matope, Gift, Guerrini, Laure, Pfukenyi, Davies, Cappelle, Julien, Mwandiringana, Ellen, Missé, Dorothée, Gori, Elizabeth, Bourgarel, Mathieu, Liégeois, Florian

“…By combining data from our previous work on Coronaviruses, we also anaylzed co-infection of bats with Coronaviruses and Astroviruses at Magweto and Chirundu sites for which the prevalence of co-infection was 2.6% and 3.5% respectively. …”
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Evaluation of oral cholera vaccine (Euvichol-Plus) effectiveness against Vibrio cholerae in Bangladesh: an interim analysis by Amanda Tiffany, Ashraful Islam Khan, Firdausi Qadri, John D Clemens, Faisal Ahmmed, Farhana Khanam, Tahmina Shirin, Fahima Chowdhury, Md. Taufiqul Islam, Md Nazmul Islam, Md Nazmul Hasan Rajib, Md Ismail Hossen, Md. Taufiqur Rahman Bhuiyan, Shahinur Haque, Prasanta Kumar Biswas, Amirul Islam Bhuiyan, Zahid Hasan Khan, Mohammad Ashraful Amin, Aninda Rahman, S M Shahriar Rizvi, Lucy Breakwell

“…Using this vaccine in a cholera epidemic in Dhaka, Bangladesh, provided the opportunity to evaluate the vaccine effectiveness (VE) using a test-negative design.Methods A two-dose regimen of Euvichol-Plus was administered to individuals aged &gt;1 year in a population of ca. 900 000 in two campaign rounds between June and August 2022, with prospective registration of all persons who received at least one dose. We conducted systematic surveillance in two key facilities, enrolling patients with acute watery diarrhoea who were eligible for vaccination from the campaign’s start and who presented for care between 21 August 2022 and 20 August 2023. …”
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Comparative Analysis of the Enzymatic, Coagulant, and Neuromuscular Activities of Two Variants of <i>Crotalus durissus ruruima</i> Venom and Antivenom Efficacy by Poliana J. Demico, Isabele N. Oliveira, Vitória S. Proença-Hirata, Samuel R. Dias, Hugo A. Ghirotti, Elisangela O. Silva, Inês C. Giometti, Francis L. Pacagnelli, Kristian A. Torres-Bonilla, Stephen Hyslop, Nathália C. Galizio, Karen de Morais-Zani, Manuela B. Pucca, Anderson M. Rocha, Jéssica B. Maciel, Marco A. Sartim, Wuelton M. Monteiro, Rafael S. Floriano

“…<b>Background:</b> We compared the enzymatic, coagulant, and neuromuscular activities of two variants (yellow—CDRy and white—CDRw) of <i>Crotalus durissus ruruima</i> venom with a sample of <i>C. d. terrificus</i> (CDT) venom and examined their neutralization by antivenom against CDT venom. …”
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