Prenatal vitamin utilization and its determinants among pregnant women in south Gondar zone: multicenter cross-sectional study by Begizew Yimenu Mekuriaw, Dagne Addisu, Wassie Yazie Ferede, Fillorenes Ayalew Sisay, Assefa kebie Mitiku, Tegegne Wale Belachew, Tigist Seid Yimer, Habtie Bantider Wubet, Selamawit Girma Tadesse, Negesse Zurbachew Gobezie, Alemie Fentie Mebratie, Moges Kefale Alachew, Temesgen Dessie Mengistu, Yonas Zenebe Yiregu, Rahel Birhanu Arage, Anteneh Mengist Dessie, Fikadu Geremew Gebeyehu, Geremew Bishaw Mekonen, Habtam Desse Alemayehu, Abeba Belay Ayalew, Yitayal Ayalew Goshu, Besfat Berihun Erega

“…Statistical significance was declared at 95%CI and p-value < 0.05.ResultIn this study, we found that 87.5% (95% CI: 84.31, 90.34) of pregnant women did not use prenatal vitamins. …”
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Evaluation of Ecological Resilience of Agricultural Ecosystems in Razavi Khorasan Province: Comparison of Integrated and Non-Integrated Ecosystems by Pegah Naghipour, Alireza Koocheki, Mahdi Nasiri mahalati, Soroor Khorramdel

“…The main findings indicated that the integrated farmlands with other activities particularly with animal husbandry is much more resilient than pure and monotype farm production systems.AcknowledgementsWe are grateful to the Honorable Vice Chancellor of Research and Technology of Ferdowsi University of Mashhad for providing the costs of this research.…”
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Deep application of controlled-release urea increases the yield and saponin content of Panax notoginseng by regulating soil nitrate distribution by Yun-xia Su, Yun-xia Su, Yun-xia Su, Ping Zhao, Li-jie Jia, Li-jie Jia, Li-jie Jia, Yuan-feng Cao, Guan-ze Liu, Guan-ze Liu, Jun-wen Chen, Jun-wen Chen, Sheng-chao Yang, Sheng-chao Yang, Yan-li Zhou, Guang-qiang Long, Guang-qiang Long, Guang-qiang Long

“…However, its effects on P. notoginseng yield and quality, a medicinal plant with a prolonged nutrient acquisition duration, remain unclear.MethodsIn this study, we conducted a two-year field plot experiment to investigate the effect of CRU on P. notoginseng with three placement depths (0, 6, and 12 cm denoted as R0, R6, and R12, respectively) at an application dosage of 250 kg N ha-1 with biochar addition (R6B) and 20% N reduction (R6R) based on the R6, with conventional fertilization (250 kg N ha-1, common urea) serving as the control (CK).ResultsOur results indicated that yields increased by 27.1–37.6% with R0, R6, R12, and R6B, while remaining stable with R6R compared to CK. …”
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COVID-19 and HIV: Clinical Outcomes and Inflammatory Markers in a Cohort from a Reference Hospital in Rio de Janeiro, Brazil by Nathalia Beatriz Ramos de Sá, Karine Venegas Macieira, Mariana Rosa Inacio Coelho, Milena Neira Goulart, Marcelo Ribeiro-Alves, Leonardo Azevedo da Silva Rosadas, Kim Mattos Geraldo, Maria Pia Diniz Ribeiro, Sandra Wagner Cardoso, Beatriz Grinsztejn, Valdiléa G. Veloso, Andressa da Silva Cazote, Dalziza Victalina de Almeida, Carmem Beatriz Wagner Giacoia-Gripp, Fernanda Heloise Côrtes, Mariza Gonçalves Morgado

“…This study describes inflammatory markers in COVID-19 clinical outcomes with and without HIV infection. Methods: We analyzed 112 inpatients of the Hospital Center for COVID-19 (INI/FIOCRUZ), including 22 cases of COVID-19 in PLWH (COVID/PLWH group). …”
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Proteogenomic annotation of T6SS components identified in Bacteroides fragilis secretome by Natalya B. Zakharzhevskaya, Olga Yu Shagaleeva, Daria A. Kashatnikova, Daria A. Kashatnikova, Anton O. Goncharov, Anton O. Goncharov, Daria V. Evsyutina, Dmitry A. Kardonsky, Elizaveta A. Vorobeva, Artemiy S. Silantiev, Viktoria D. Kazakova, Irina V. Kolesnikova, Ivan O. Butenko, Anna A. Vanyushkina, Svetlana V. Smirnova, Andrei V. Chaplin, Andrei V. Chaplin, Boris A. Efimov, Boris A. Efimov

“…Proteomic annotation of T6SS components and detailed descriptions of all immune-effector pairs are currently available. In this research, we performed detailed proteogenomic analysis and subsequent proteomic annotation of the T6SS components of the toxigenic Bf BOB25.Material and methodsFractionated cells, cultivated media and vesicles were prepared for proteome analysis by HPLC-MS/MS. …”
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Towards Better Perovskite Absorber Materials: Cu+ Doping Improves Photostability and Radiation Hardness of Complex Lead Halides by Marina I. Ustinova, Maxim N. Sarychev, Nikita A. Emelianov, Yiqun Li, Yuling Zhuo, Tongjun Zheng, Sergey D. Babenko, Evgeniy D. Tarasov, Pavel P. Kushch, Nadezhda N. Dremova, Galina A. Kichigina, Alexandra V. Rasmetyeva, Andrey I. Kukharenko, Dmitry P. Kiryukhin, Ernst Z. Kurmaev, Xueqing Xu, Pavel A. Troshin, Lyubov A. Frolova, Ivan S. Zhidkov

“…Importantly, the presence of Cu+ enhances photostability of perovskite films and blocks the formation of metallic lead as a photolysis product. Furthermore, we have carried out one of the first studies on the radiation hardness of complex lead halides exposed to two different stressors: γ‐rays and 8.5 MeV electron beams. …”
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Impact of remnant cholesterol on short-term and long-term prognosis in patients with prediabetes or diabetes undergoing coronary artery bypass grafting: a large-scale cohort study by Zhongchen Li, Chunyu Yu, Heng Zhang, Runze Chen, Yan Zhao, Zhe Zheng

“…In our study, 13,426 CABG patients with prediabetes or diabetes were enrolled from a large longitudinal cohort to assess the impact of remnant-C on both perioperative and long-term outcomes. We found that higher remnant-C levels were significantly associated with an increased risk of acute kidney injury (AKI) perioperatively, as well as long-term adverse outcomes, including major adverse cardiovascular and cerebrovascular events (MACCEs), independent of LDL-C levels. …”
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The impact of preliminary patient hydration on physiological [18F]PSMA-1007 uptake in the urinary bladder on PET/CT by T. L. Antonevskaya, A. I. Khalimon, O. V. Mukhortova, M. M. Khodzhibekova, A. I. Nikiforuk, D. D. Zubkov, G. F. Khamadeeva, D. Yu. Khodakova, T. N. Lazutina, I. V. Pylova, A. V. Leontyev, I. P. Aslanidi

“…Nevertheless, in our clinical practice, we routinely observed a notably high [ 18F]PSMA‑1007 uptake in the urinary bladder. …”
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Construct validation of a complete postpartum health and well-being patient reported outcome measure: prospective cohort studyAJOG Global Reports at a Glance by Laura J. O'Byrne, BMBS, MSc, PhD, Gillian M. Maher, PhD, Jill M. Mitchell, MB, BCh, BAO, Ali S Khashan, PhD, Richard M. Greene, MB, BCh, BAO, John P. Browne, PhD, Fergus P. McCarthy, MB, BCh, BAO, PhD

“…The PROM was administered at T1=first week postpartum, T2=6 weeks and T3=12 weeks postpartum. We evaluated the construct validity of these tools through hypothesis testing, proposing that: (1) the instrument should differentiate between groups with and without morbidity, (2) the instrument should differentiate between groups based on delivery type, and (3) should detect change over the postpartum period. …”
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Virtual reality-based cognitive–behavioural therapy for the treatment of anxiety in patients with acute myocardial infarction: a randomised clinical trial by Jiajun Weng, Junbo Ge, Jiajia Liu, Juying Qian, Xiao Huang, Yuanyuan Li, Juan Peng, Yan'e Lu, Dong Huang, Pingyuan Yang, Shikun Xu, Lihua Guan, Qibing Wang, Zexin Zhao, Yabin Wei

“…Providing timely and easily accessible psychological interventions using virtual reality-based cognitive–behavioural therapy (VR-CBT) could potentially improve both acute and long-term symptoms affecting their mental health.Aims We aim to examine the effectiveness of VR-CBT on anxiety symptoms in patients with AMI who were admitted to the intensive care unit (ICU) during the acute stage of their illness.Methods In this single-blind randomised clinical trial, participants with anxiety symptoms who were admitted to the ICU due to AMI were continuously recruited from December 2022 to February 2023. …”
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Innovative models of healthcare delivery: an umbrella review of reviews by Frances Rapport, Jeffrey Braithwaite, Yvonne Zurynski, Peter D Hibbert, Kate Churruca, Louise A Ellis, Chiara Pomare, Robyn Clay-Williams, Stephanie Best, Janet C Long, Gaston Arnolda, Bróna Nic Giolla Easpaig, Zeyad Mahmoud, Mitchell N Sarkies, Hoa Mi Nguyen, Karen Hutchinson, Gilbert Thomas Knaggs, Katherine Maka, Elizabeth E Austin, Diana Fajardo Pulido, Sarah Hatem, Natalie Roberts, Emilie Francis Auton, Genevieve Dammery, Isabelle Meulenbroeks, Ann Carrigan, Mai-Tran Nguyen

“…The findings indicate that the innovative models of healthcare we identified in this review may be effective in managing patients with a range of acute and chronic conditions. …”
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The Impact of the COVID-19 Pandemic on Health and Health Care Experience in Those With Polycystic Ovary Syndrome by Sydora BC, Wilke MS, Ghosh M, Vine DF

“…Because of its complexity, PCOS requires a multidisciplinary health care approach including endocrinologists, gynecologists, dietician, exercise specialists, and psychologists/psychiatrists. In this paper, we describe the findings of a self-administered survey in those who self-reported having PCOS. …”
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High SUVs Have More Robust Repeatability in Patients with Metastatic Prostate Cancer: Results from a Prospective Test-Retest Cohort Imaged with 18F-DCFPyL by Rudolf A. Werner, Bilêl Habacha, Susanne Lütje, Lena Bundschuh, Takahiro Higuchi, Philipp Hartrampf, Sebastian E. Serfling, Thorsten Derlin, Constantin Lapa, Andreas K. Buck, Markus Essler, Kenneth J. Pienta, Mario A. Eisenberger, Mark C. Markowski, Laura Shinehouse, Rehab AbdAllah, Ali Salavati, Martin A. Lodge, Martin G. Pomper, Michael A. Gorin, Ralph A. Bundschuh, Steven P. Rowe

“…Thus, readers deciding on RLT must have certainty on the repeatability of PSMA uptake metrics. As such, we aimed to evaluate the test-retest repeatability of lesion uptake in a large cohort of patients imaged with 18F-DCFPyL. …”
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Deep immunophenotyping of circulating immune cells in major depressive disorder patients reveals immune correlates of clinical course and treatment response by Fabiola Stolfi, Claudio Brasso, Davide Raineri, Virginia Landra, Camilla Barbero Mazzucca, Ali Ghazanfar, Lorenza Scotti, Riccardo Sinella, Vincenzo Villari, Giuseppe Cappellano, Paola Rocca, Annalisa Chiocchetti

“…Multiparametric analysis was performed on the peripheral blood of 60 MDD patients using flow cytometry to identify lymphocytes (naïve/effector, memory, regulatory) and myeloid cells (dendritic cells, monocytes). We studied the associations between immunophenotype and depressive symptoms, social and working functioning, and subjective quality of life during the acute phase and after three months of treatment. …”
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On Bridge Graphs with Local Antimagic Chromatic Number 3 by Wai-Chee Shiu, Gee-Choon Lau, Ruixue Zhang

“…The local antimagic chromatic number <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><msub><mi>χ</mi><mrow><mi>l</mi><mi>a</mi></mrow></msub><mrow><mo>(</mo><mi>G</mi><mo>)</mo></mrow></mrow></semantics></math></inline-formula> is the minimum number of colors taken over all colorings induced by local antimagic labelings of <i>G</i>. In this paper, we present some families of bridge graphs with <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><msub><mi>χ</mi><mrow><mi>l</mi><mi>a</mi></mrow></msub><mrow><mo>(</mo><mi>G</mi><mo>)</mo></mrow><mo>=</mo><mn>3</mn></mrow></semantics></math></inline-formula> and give several ways to construct bridge graphs with <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><msub><mi>χ</mi><mrow><mi>l</mi><mi>a</mi></mrow></msub><mrow><mo>(</mo><mi>G</mi><mo>)</mo></mrow><mo>=</mo><mn>3</mn></mrow></semantics></math></inline-formula>.…”
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Urine kidney injury molecule-1 predicts subclinical kidney disease among persons living with HIV initiating tenofovir disoproxil fumarate-based ART in Zambia by Freeman W. Chabala, Edward D. Siew, Edward D. Siew, Edward D. Siew, C. William Wester, C. William Wester, Alana T. Brennan, Alana T. Brennan, Alana T. Brennan, Masauso M. Phiri, Michael J. Vinikoor, Michael J. Vinikoor, Sepiso K. Masenga, Muktar H. Aliyu, Muktar H. Aliyu, Muktar H. Aliyu

“…ART-naïve PLWH who were starting treatment with TDF with intact kidney function [estimated glomerular filtration rate (eGFR)&gt; 60 mL/min/1.73m2] were followed at initiation, 2 weeks, and approximately 3 months to determine the incidence of TDF-associated nephrotoxicity. We measured urine KIM-1 and NGAL at baseline and after 2 weeks of treatment to determine if it predicted subclinical nephrotoxicity. …”
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Germline structural variant as the cause of Lynch Syndrome in a family from Ecuador by Gemma Llargués-Sistac, Laia Bonjoch, Jenifer Muñoz, Xavier Domínguez-Rovira, Teresa Ocaña, Maria Isabel Alvarez-Mora, Celia Badenas, Anna Esteve-Codina, Carlos Reyes-Silva, Gabriela Jaramillo-Koupermann, Maria Teresa Rodrigo, Sandra López-Prades, Miriam Cuatrecasas, Antoni Castells, Francesc Balaguer, Leticia Moreira, Guerau Fernandez, Sergi Castellví-Bel

“…Current approaches for LS molecular diagnosis typically involve screening of the MMR genes by targeted gene-panel sequencing and rearrangement screening. We report the identification and characterization of a novel germline structural variant encompassing 48.757 kb, involving the 3’-ends of the MLH1 and LRRFIP2 genes, as the cause of LS in a family of Ecuador. …”
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MicroRNAs Expression Profile in MN1-Altered Astroblastoma by Francesca Gianno, Evelina Miele, Claudia Sabato, Elisabetta Ferretti, Simone Minasi, Francesca Romana Buttarelli, Debora Salerno, Natalia Pediconi, Giuseppe Rubens Pascucci, Francesca Guerrieri, Andrea Ciolfi, Simone Pizzi, Maura Massimino, Veronica Biassoni, Elisabetta Schiavello, Marco Gessi, Sofia Asioli, Angela Mastronuzzi, Antonio d’Amati, Giuseppina Catanzaro, Elisabetta Viscardi, David Capper, Felice Giangaspero, Manila Antonelli

“…MicroRNAs (miRNAs) are important gene expression regulators with strong implications in biological processes. Here, we investigated microRNA expression, regulation, and biological processes correlated to target genes of deregulated miRNAs in MN1-altered astroblastoma. …”
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DS2 designer pre-fusion F vaccine induces strong and protective antibody response against RSV infection by Yiling Yang, Ruoke Wang, Fenglin Guo, Tian Zhao, Yuqing Lei, Qianqian Yang, Yige Zeng, Ziqing Yang, Tatchapon Ajavavarakula, Ruijie Tan, Mingxi Li, Haodi Dong, Mengyue Niu, Keyan Bao, Hao Geng, Qining Lv, Qi Zhang, Xuanling Shi, Peng Liu, Jiwan Ge, Xinquan Wang, Linqi Zhang

“…However, their immunogenicity has not been directly compared. In this study, we generated three recombinant vaccines using the chimpanzee adenovirus vector AdC68 to express DS-Cav1, SC-TM, and DS2. …”
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Exploration of the mechanism of Lithospermum erythrorhizon oil in treating atopic dermatitis based on network pharmacology and experimental validation of the PI3K-Akt pathway regul... by Weisheng Hu, Yinlan Wang, Yingjie Zhou, Junbao Shi, Zengyan Li, Xiaoling Jiang, Qinyuan Wu, Changming Zhong, Huilan Weng, Sijie Ouyang, Yuan Jing, Xianxiang Cai, Mingda Ye, Ning Huang

“…Methods: Utilizing a network pharmacology approach integrated with experimental validation, we identified active components and potential targets of Lithospermum erythrorhizon oil via TCMSP, ChemSrc, PubChem, and PharmMapper. …”
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