Can Underlying Co-Morbidities Affect Cerebral Oximetry in Cardiac Surgery Patients? by Kianoush Saberi, Shahnaz Sharifi, Amirhossein Orandi

“…To add details, according to literatures about CVA 28% of patients had (Cerebrovascular Accident), 74% IHD (Ischemic Heart Disease), 82% HTN (Hypertension), 52% DM (Diabetes Mellitus), 61% Smoking History, 36% CKD (Chronic Kidney Disease) and 42% CHF (Congestive Heart Failure). …”
Get full text

General medical comorbidities in psychotic disorders in the Finnish SUPER study by Johan Ahti, Tuula Kieseppä, Willehard Haaki, Jaana Suvisaari, Solja Niemelä, Kimmo Suokas, Minna Holm, Asko Wegelius, Olli Kampman, Markku Lähteenvuo, Tiina Paunio, Jari Tiihonen, Jarmo Hietala, Erkki Isometsä

“…Registry-based diagnoses of psychotic disorders and hypertension, diabetes, chronic obstructive pulmonary disease (COPD), cancers, ischemic heart disease, and liver disorders were obtained. …”
Get full text

Evaluating the Relationship of GDF-15 with Clinical Characteristics, Cardinal Features, and Survival in Multiple Myeloma by Małgorzata Banaszkiewicz, Jolanta Małyszko, Krzysztof Batko, Ewa Koc-Żórawska, Marcin Żórawski, Paulina Dumnicka, Artur Jurczyszyn, Karolina Woziwodzka, Joanna Tisończyk, Marcin Krzanowski, Jacek Małyszko, Anna Waszczuk-Gajda, Ryszard Drożdż, Marek Kuźniewski, Katarzyna Krzanowska

Get full text

In vitro gastrointestinal digestion simulation screening of novel ACEI peptides from broccoli: mechanism in high glucose-induced VSMCs dysfunction by Shuzhi Zhang, Jingjing Guo, Shikun Suo, Li Ju, Zhaoqiang Jiang, Pingshuan Dong, Yanli Wang, Yali Dang, Laijing Du

“…Therefore, it can be further referenced for the functional food against hypertension and cardiovascular diseases.…”
Get full text

Emerging Pharmacological Interventions for Chronic Venous Insufficiency: A Comprehensive Systematic Review and Meta-Analysis of Efficacy, Safety, and Therapeutic Advances by Camila Botelho Miguel, Ranielly de Souza Andrade, Laise Mazurek, Melissa Carvalho Martins-de-Abreu, Jamil Miguel-Neto, Aurélio de Melo Barbosa, Glicélia Pereira Silva, Aristóteles Góes-Neto, Siomar de Castro Soares, Javier Emilio Lazo-Chica, Wellington Francisco Rodrigues

“…<b>Background/Objectives:</b> Chronic Venous Insufficiency (CVI) is a progressive vascular condition characterized by venous hypertension and chronic inflammation, leading to significant clinical and socioeconomic impacts. …”
Get full text

Idiopathic pulmonary fibrosis is a risk factor for cardiovascular disease: potential role of KL-6 and systemic inflammation by Mohamed F. AbdelGhany, Waleed GamalEldin Khaleel, Asmaa Omar Ahmed, Ahmad BaheyElden Ahmed, Lamees M. Bakkar

“…Sixty out of the 134 documented IPF patients had cardiovascular comorbidities (44.7%), cardiomyopathy (mean ± SD: 43.63 ± 10.56), pulmonary hypertension (mean ± SD: 41.67 ± 15.32), ECG-ischemic changes (40.0%), and atrial fibrillation (13.3%). …”
Get full text

Response to Statin Therapy in Obstructive Sleep Apnea Syndrome: A Multicenter Randomized Controlled Trial by Marie Joyeux-Faure, Renaud Tamisier, Jean-Philippe Baguet, Sonia Dias-Domingos, Stephen Perrig, Georges Leftheriotis, Jean-Paul Janssens, Wojciech Trzepizur, Sandrine H. Launois, Françoise Stanke-Labesque, Patrick A. Lévy, Frédéric Gagnadoux, Jean-Louis Pepin

“…Accumulated evidence implicates sympathetic activation as inducing oxidative stress and systemic inflammation, which in turn lead to hypertension, endothelial dysfunction, and atherosclerosis in obstructive sleep apnea (OSA). …”
Get full text

Spectrum of thyroid disorders among patients with type 2 diabetes mellitus by Md Rakibul Hasan, Raisa Siddika, Sayma Akther Mou, Md Shahed Morshed

“…Female sex (OR: 3.0, 95%CI: 1.5, 6.1, p=0.003) and obesity (OR: 2.3, 95%CI: 1.1, 5.0, p=0.039) had higher odds of having a diagnosis of overt hypothyroidism among patients with T2DM. Hypertension, dyslipidemia and obesity were significantly (p < 0.05) higher in diabetic patients with overt hypothyroidism. …”
Get full text

Nonclassical Axis of the Renin-Angiotensin System and Neprilysin: Key Mediators That Underlie the Cardioprotective Effect of PPAR-Alpha Activation during Myocardial Ischemia in a M... by María Sánchez-Aguilar, Luz Ibarra-Lara, Leonardo del Valle-Mondragón, Elizabeth Soria-Castro, Juan Carlos Torres-Narváez, Elizabeth Carreón-Torres, Alicia Sánchez-Mendoza, María Esther Rubio-Ruíz

“…Recently, nonclassical RAS components have been implicated in the pathogenesis of hypertension and myocardial dysfunction; however, their cardiac functions are still controversial. …”
Get full text

Global longitudinal strain and its dynamics after replacement of aortal valve in patients with severe aortic stenosis by N.V. Ponych, O.O. Nemchyna, O.J. Zharinov, O.A. Yepanchintseva, B.M. Todurov

“…In turn, the positive dynamics of GLS significantly depended on the initial functional class of heart failure, the stage of arterial hypertension, the degree of tricuspid insufficiency, LV EF, the index of volume LA in the preoperative period. …”
Get full text

Clinical code usage in UK general practice: a cohort study exploring 18 conditions over 14 years by Christos Grigoroglou, Darren M Ashcroft, Evangelos Kontopantelis, David Reeves, Salwa S Zghebi, Rosa Parisi, Brian McMillan

“…Objective To assess the diagnostic Read code usage for 18 conditions by examining their frequency and diversity in UK primary care between 2000 and 2013.Design Population-based cohort studySetting 684 UK general practices contributing data to the Clinical Practice Research Datalink (CPRD) GOLD.Participants Patients with clinical codes for at least one of asthma, chronic obstructive pulmonary disease, diabetes, hypertension (HT), coronary heart disease, atrial fibrillation (AF), heart failure, stroke, hypothyroidism, chronic kidney disease, learning disability (LD), depression, dementia, epilepsy, severe mental illness (SMI), osteoarthritis, osteoporosis and cancer.Primary and secondary outcome measures For the frequency ranking of clinical codes, canonical correlation analysis was applied to correlations of clinical code usage of 1, 3 and 5 years. …”
Get full text

The influencing factors of cognitive impairment in elderly individuals in Chengdu city: a cross-sectional study based on AD8 by Xi Ruan, Hongyi Li, Ziqi Wang, Yu Wang, Yamei Nie, Yan Li, Yuanjing Li, Qin Fan, Baiwei Ni, Yinxue Huang, Xuan Hong, Ting Sun, Yuan Luo, Shoukang Zou

“…The risk factors for cognitive impairment in elderly individuals included advanced age, hypertension, heart disease, diabetes, cerebrovascular disease, depressive symptoms, and anxiety symptoms, while the protective factors included higher education level, married status, and greater life satisfaction. …”
Get full text

Pre-IVF treatment with a GnRH antagonist in women with endometriosis (PREGNANT): study protocol for a prospective, double-blind, placebo-controlled trial by Hugh Taylor, Hao Huang, Lubna Pal, Heping Zhang, Howard J Li, Sandra Carson, Valerie Flores, Jared Robbins, Nanette F Santoro, James H Segars, David Seifer, Steven Young

“…Secondary outcomes include oocyte number, fertilisation rate, embryo morphology and implantation rates, as well as rates of known endometriosis-related obstetrical outcomes (pregnancy-induced hypertension, antepartum haemorrhage, caesarean delivery and preterm birth).Ethics and dissemination The PREGnant trial was approved by the Institutional Review Board at Johns Hopkins University. …”
Get full text

Clinical features of autonomic dysfunction in children with anti-N-methyl-D aspartic receptor encephalitis by Dongqing Li, Jing Sun, Guannan Li, Shuo Miao, Jian Yang, Jianzhao Zhang

“…The most prevalent symptom of autonomic dysfunction was cardiovascular autonomic dysfunction(21/22, 95%),with the specific manifestations being sinus tachycardia (8 cases), ventricular premature beats (2 cases), atrioventricular block (2 cases), atrial premature beats (3 cases), and sinus bradycardia (4 cases),hypertension(1 case) and cardiac arrest(1 case). Other symptoms included gland secretion dysfunction (19/22, 86%),ventilate dysfunction(3/22,14%), thermoregulatory dysfunction (3/22,14%), bladder dysfunction(2/22,9%). …”
Get full text

Identification of Interactive Genetic Loci Linked to Insulin Resistance in Metabolic Syndrome—An Update by Imadeldin Elfaki, Rashid Mir, Mohamed E. Elnageeb, Abdullah Hamadi, Zeyad M. Alharbi, Ruqaiah I. Bedaiwi, Jamsheed Javid, Tariq Alrasheed, Dalal Alatawi, Basmah M. Alrohaf, Mohammed K. Abunab, Turki Ahmed Muqri

“…Metabolic syndrome is a metabolic disorder characterized by hypertension, dyslipidemia, impaired glucose tolerance, and abdominal obesity. …”
Get full text

How Does Indonesian Chronic Disease Patient Adhere to Their Treatment? A Cross-Sectional Analysis of 11,408 Subjects by Pradipta IS, Aprilio K, Ningsih YF, Pratama MAA, Gatera VA, Alfian SD, Iskandarsyah A, Abdulah R

“…Treatment nonadherence was notable in subjects with liver disease (61.8%), tuberculosis (59.8%), digestive diseases (57.9%), other lung diseases (56.8%), psychiatric diseases (51.6%), asthma (51.2%), and hypertension (50%). Treatment nonadherence was associated with socioeconomic-related factors of being aged 15– 65 years, living in rural areas, having history of formal education, and having a household size of 2– 6 people. …”
Get full text

CYSTIC DEGENERATION OF THE DUODENUM ASSOCIATED WITH CHRONIC PANCREATITIS by A. G. Kriger, A. V. Smirnov, S. V. Berelavichus, D. S. Gorin, N. N. Vetsheva, Ja. I. Nerestjuk, D. V. Kalinin, A. V. Glotov

“…Clinical presentation of DD was not related with etiology and showed typical symptoms of CP: abdominal pain occurred in 98.8% of patients, body weight loss – 61.7%, duodenal obstruction – 35.8%, biliary hypertension – 34.1%. The overall morbidity was 35.1%. …”
Get full text

Abnormalities in Blood Parameters in Athletes Taking Anabolic Androgenic Steroidal Agents; an Observational Clinical Study by Mubarak GS, Bamagous GA, Alsanosi SM, Alhindi YZ, Alqashqari HS, Albar HT, Siddiqi AM, Ayoub N, Falemban AH

“…Seventy-four percent of the participants reported side effects, and 28% had received a medical diagnosis, such as hypertension, hyperlipidemia or an infertility. High levels of testosterone, prolactin, alanine transaminase (ALT), aspartate transferase (AST) and lipid profile, and low luteinizing hormone (LH) and follicle-stimulating hormone (FSH) were observed.Conclusion: The unsupervised use of AAS alone or in combination with other hormones and/or supplements may lead to adverse effects. …”
Get full text

First results of the EuroHeart program by András Jánosi, Zoltán Járai

“…Common comorbidities were hypertension and diabetes (67.9% and 28%, respectively). …”
Get full text

A genetic exploration of the relationship between posttraumatic stress disorder and cardiovascular diseases by Eva Lukas, Rada R. Veeneman, Dirk J. A. Smit, Tarunveer S. Ahluwalia, Jentien M. Vermeulen, Gita A. Pathak, Renato Polimanti, Karin J. H. Verweij, Jorien L. Treur

“…We leveraged summary-level data of genome-wide association studies (PTSD: N = 1,222,882; atrial fibrillation (AF): N = 482,409; coronary artery disease (CAD): N = 1,165,690; hypertension (HT): N = 458,554; heart failure (HF): N = 977,323). …”
Get full text