Serum Matrix Metalloproteinase 9 and Macrophage Migration Inhibitory Factor (MIF) Are Increased in Young Healthy Nonobese Subjects with Positive Family History of Type 2 Diabetes by Agnieszka Nikołajuk, Natalia Matulewicz, Magdalena Stefanowicz, Monika Karczewska-Kupczewska

“…Insulin resistance increases the risk for cardiovascular disease (CVD) even in the absence of classic risk factors, such as hyperglycemia, hypertension, dyslipidemia, and obesity. Low-grade chronic inflammatory state is associated both with insulin resistance and atherosclerosis. …”
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Changes in Glucose Metabolism and Atherogenic Risk Factors in Diabetic Patients’ First-degree Relatives by María Teresa González Pedroso, Elizabeth Remis Rodríguez, Marlene Ferrer Arrocha, Marisela Nuez Villar, Ingrid Rodríguez Crespo, Héctor Pérez Assef

“…The most frequent risk factor was dyslipidemia, present in 43,4 % followed by arterial hypertension and overweight/obesity. Alterations in glucose metabolism occurred in 74,6 % of the patients, with a predominance of altered fasting glycemia in 30,3 % and 11,5 % diagnosed with diabetes mellitus. …”
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Impact of maternal prenatal stress by glucocorticoids on metabolic and cardiovascular outcomes in their offspring: A systematic scoping review. by Claudia Eberle, Teresa Fasig, Franziska Brüseke, Stefanie Stichling

“…However, maternal risk factor "stress", is clearly linked to adverse cardio-metabolic offspring outcomes, postnatally, such as obesity, hyperglycemia, insulin resistance, diabetes mellitus (DM), Metabolic Syndrome (MetS), cardiovascular disease (CD), hypertension, restricted fetal growth as well as reduced birth, adrenal, and pancreas weights.…”
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Conducting genetic epidemiology research on hyperuricaemia and gout in an indigenous community in Guam - a feasibility study by Yvette C. Paulino, Frank Camacho, Tristan VC Paulino, Delores J. Lee, Lisa Linda Natividad, Elizabeth Matisoo-Smith, Tony R. Merriman, Anna L. Gosling

“…The prevalence of metabolic conditions from highest to lowest were obesity (55.6%), hyperuricaemia (36.0%), hypertension (27.8%), gout (23.0%), diabetes (14.9%), cardiovascular disease (8.4%), kidney disease (7.3%), and liver disease (3.4%). …”
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Enhancing Therapy Adherence: Impact on Clinical Outcomes, Healthcare Costs, and Patient Quality of Life by Urszula Religioni, Rocío Barrios-Rodríguez, Pilar Requena, Mariola Borowska, Janusz Ostrowski

“…Adherence to therapy, defined as the extent to which a patient follows prescribed therapeutic recommendations, is a pivotal factor in the effective management of chronic diseases such as diabetes, hypertension, and cardiovascular conditions. This review highlights the profound influence of adherence on clinical outcomes, healthcare costs, and patient quality of life. …”
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Tryptophan as a biomarker of pregnancy-related immune expression and modulation: an integrative review by Stephanie Prescott, Stephanie Prescott, Natasa Billeci, Melissa Gotcher, Sapna Patel, Addison Almon, Hailey Morgan, Danielle Abukhalaf, Maureen Groer

“…We included 16 quality studies with direct measurement of TRP in pregnancy including ten prospective cohorts, four case-control studies, and two cross-sectional studies.ResultsTRP levels are reduced both pre- and postnatally in women with depressive symptoms, but not during pregnancy, though the TRP/Kynurenine pathway is disturbed during pregnancy in women with depressive symptoms, women with prolonged labor, women with gestational hypertension, and in adverse outcomes of pregnancy including prematurity and growth restriction.ConclusionTRP and its metabolites hold promise as biomarkers for various pregnancy-related outcomes. …”
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Thyroid Storm with Multiorgan Failure Treated with Plasmapheresis by Ann Miller, Kristi D. Silver

“…A 50-year-old male with a history of hyperthyroidism, hypertension, and congestive heart failure presented to another hospital with fever and altered mentation. …”
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Blood Pressure Exploration in the November 27th Health Area Population from Marianao Municipality by Moura Revueltas Aguero, Yamilé Valdés González, Silvia Serra Larín, Carlos Barceló Pérez, Juan Carlos Ramírez Sotolongo, Ramón Suárez Medina

“…There were 68 people with a diagnosis of hypertension the 44.7 % and suspected hypertensive the 4.6 %, upon consolidation, a prevalence of 49.3 % was reached. …”
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Mean Platelet Volume in Ocular Behçet’s Disease by Fatih Mehmet Türkcü, Abdullah Kürşat Cingü, Harun Yüksel, Yasin Çınar, Meltem Akkurt, Muhammed Şahin, Zeynep Özkurt, Alparslan Şahin, İhsan Çaça

“…These patients had no past history of smoking, drug use, or systemic diseases including diabetes mellitus, hypertension, cardiovascular disease, and renal disease. …”
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Profile and outcomes of retinal artery occlusion: The underrealized need to expedite presentation by Yogita Kadam, Anthony V Das, Raja Narayanan, Neelima Balakrishnan, Praneet Telukunta, Brijesh Takkar

“…Hyperhomocysteinemia had a higher association (1.95, P = 0.0019) with younger patients (<40 years), while hypertension (3.64, P < 0.001), diabetes mellitus (DM; 4.18, P < 0.001), and coronary artery disease (CAD) (4.26, P = 0.002) were significantly commoner in older patients. …”
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Clinical management of female patients with Fabry disease based on expert consensus by Eva Brand, Aleš Linhart, Patrick Deegan, Ruxandra Jurcut, Antonio Pisani, Roser Torra, Ulla Feldt-Rasmussen

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Supplemental technologies of liver ultrasound investigation at the 1-st type tyrosinemia in pediatrics by G. M. Dvoryakovskaya, S. A. Ivleva, I. V. Dvoryakovsky, S. I. Polyakova

“…Traditional US-investigation of hemodynamic parameters of portal system blood flow reveals early US-signs of portal hypertension. Color mapping (ASQ technique) allows visual estimation of fibrosis severity and amount of functioning parenchyma. …”
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Acute Myocardial Infarction and Predisposing Risk Factors by Julio Armando Sánchez Delgado, Nailé Edita Sánchez Lara, Yalith Pavón Rodríguez, Zulema Castro Vega

“…The risk factors, arterial hypertension (X2=25.4 OR=14 95 % CI (4.6; 42.3) and family history of cardiovascular disease (X2=5.2 OR=2.9 95 % CI (1, 1; 7.4)) expressed a highly significant association for acute myocardial infarction. …”
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Sex, Prescribing Practices and Guideline Recommended, Blood Pressure, and LDL Cholesterol Targets at Baseline in the BARI 2D Trial by Michelle F. Magee, Jacqueline E. Tamis-Holland, Jiang Lu, Vera A. Bittner, Maria Mori Brooks, Neuza Lopes, Alice K. Jacobs, BARI 2D Study Group

“…Our findings suggest that there may be sex differences in response to drug therapies used to treat diabetes, hypertension, and hyperlipidemia.…”
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Association between chronic fatigue syndrome/myalgic encephalomyelitis and cardiovascular disease by Mawulorm K. I. Denu, Ritika Revoori, Cherita Eghan, Fredrick Larbi Kwapong, Andrew Hillman, Cornelius A. Normeshie, Kofi Poku Berko, Emily L. Aidoo, Maame Araba E. Buadu

“…Multivariable logistic regression model was used to determine the association between CFS/ME and CVD, adjusting for traditional CVD risk factors (age, sex, race, hypertension, diabetes, dyslipidemia, smoking, and body mass index (BMI). …”
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The impact of SMARCA4 loss in non-small cell lung cancer therapy by Mariano Lombardi, Marianna D'Ercole, Valeria Midolo De Luca, Matteo Chiari, Lorenzo Spaggiari, Luca Bertolaccini

“…This case report explores the therapeutic impact of SMARCA4 loss in a 63-year-old female patient with a history of smoking, hypertension, hypercholesterolemia, and prior surgeries for breast and pancreatic carcinomas, who presented with a new pulmonary nodule. …”
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Understanding the Relationship Between Cerebrovascular Disease and the Gut Microbiome by William Roth, Elaine Lo, Orlando De Leon, Sajid Suriya, Farima Fakhri, James R. Brorson, Sean Polster, Tareq Kass‐Hout, Shyam Prabhakaran, James E. Siegler

“…While traditional vascular risk factors (eg, hypertension, dyslipidemia, tobacco use) account for 20% of the explained variance in carotid atherosclerosis, they remain a prominent focus for primary and secondary ischemic stroke prevention strategies. …”
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Incidence and Impact of Ventilator Associated Multidrug Resistant Pneumonia in Patients with SARS-COV2 by Seife Yohannes, Zaki Ahmed, Rachel Schelling, Swaminathan Perinkulam Sathyanarayanan, Alexandra Pratt, Mathew P. Schreiber

“…The average age of the patients was 60.58% were males, 70% were African-Americans and two-thirds of patients had diabetes, hypertension, or heart disease. The average Body Mass Index (BMI) was 32.9. …”
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Food insecurity increases the risk of overweight and chronic diseases in adolescents: a systematic review and meta-analysis by Chong Zhou, Hongrui Miao, Yingjun Zhao, Xiaohong Wan

“…Severe FI was reported to increase the risk of hypertension (OR 1.59, 95 % CI 1.281.98, P < 0.000 1). …”
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Pulmonary Embolism and Intracardiac Type A Thrombus with an Unexpected Outcome by João Português, Lucy Calvo, Margarida Oliveira, Vítor Hugo Pereira, Joana Guardado, Mário Rui Lourenço, Olga Azevedo, Francisco Ferreira, Filipa Canário-Almeida, António Lourenço

“…Transthoracic echocardiography demonstrated a free-floating type A thrombus in the right atrium, protruding into the right ventricle, and signs of pulmonary hypertension and right ventricle dysfunction. Considering the recent surgery and clinical stability, treatment with heparin alone was decided. …”
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