Clinicopathological Implications of Proteinuria after Long-Term Isolated Hematuria due to Thin Basement Membrane Nephropathy and Focal Segmental Glomerulosclerosis by Ryo Togashi, Yoshikazu Nemoto, Kaito Waki, Michito Nagura, Shigeyuki Arai, Yoshifuru Tamura, Yasutoshi Oshima, Fukuo Kondo, Ryuji Ohashi, Shunya Uchida, Shigeru Shibata, Yoshihide Fujigaki

“…At the age of 37, he developed hypertension and proteinuria which later increased up to 1.6 g/g creatinine. …”
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An implementation trial to mAnage siCkle CELl disEase through incReased AdopTion of hydroxyurEa in Nigeria (ACCELERATE): Study protocol. by Emmanuel Peprah, Joyce Gyamfi, John Patena, Hazal Kayalioglu, Tania Hameed, Gbenga Ogedegbe, Hyungrok Do, Dike Ojji, Deborah Adenikinju, Tayo Ajaye Oba, Maxwell Nwegbu, Hezekiah Isa, Grace Shedul, Alayo Y Sopekan, Obiageli E Nnodu

“…<h4>Methods</h4>This study will implement the SIM intervention, encompassing patient screening, initiation of HU treatment, and maintenance of dosage, which will be implemented via the TAsk-Strengthening Strategy for Hemoglobinopathies (TASSH TCP), derived from our team's TAsk-Strengthening Strategy for Hypertension control (TASSH) trials. Employing a sequential exploratory mixed-methods approach within the Exploration, Preparation, Implementation, and Sustainment (EPIS) framework, this study will assess SIM adoption by providers in Nigeria. …”
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Prevalence and associated factors of epiretinal membrane using spectralis OCT in Fujian Eye Study by Yang Li, Xiaoxin Li, Yonghua Hu, Bin Wang, Mingqin Zhang, Qinrui Hu

“…Multiple logistic regression showed the presence of ERM was only associated with urbanization and geographic location, but not with age, sex, refractive error, IOP, SBP, DBP, HR, BMI, hypertension, diabetic mellitus, hyperlipidemia, education, income, smoking, alcohol and tea consumption. …”
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Molecular Modeling Studies of Substituted 2,4,5-Trisubstituted Triazolinones Aryl and Nonaryl Derivatives as Angiotensin II AT1 Receptor Antagonists by Mukesh C. Sharma, D. V. Kohli, Smita Sharma

“…The development of new therapies to treat hypertension and cardiovascular diseases. A series of 2,4,5-trisubstituted triazolinones aryl and nonaryl derivatives were subjected to Group-based QSAR, k-nearest neighbour molecular field analysis, and pharmacophore mapping. …”
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The Relation of Coffee Consumption to Serum Uric Acid in Japanese Men and Women Aged 49–76 Years by Ngoc Minh Pham, Daigo Yoshida, Makiko Morita, Guang Yin, Kengo Toyomura, Keizo Ohnaka, Ryoichi Takayanagi, Suminori Kono

“…Statistical adjustment was made for body mass index, alcohol use, hypertension, diabetes mellitus, and other factors. Results. …”
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Ultrasonography of Optic Nerve Sheath Diameter in Healthy Volunteers by Ariel Sosa Remón, Wilfredo Boch Rodríguez, Dasha María García Arias, Carmen Esther Remón Chávez, Ana Esperanza Jerez Álvarez, Arian Jesús Cuba Naranjo

“…One of the deficiencies stated is the non-existence of a standard value that suggests the limit between normality and intracranial hypertension. <br /><strong>Objective:</strong> determine the diameter of the optic nerve sheath using ultrasound in healthy volunteers. …”
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Hyperbaric Oxygen Therapy in Retinal Arterial Occlusion: Epidemiology, Clinical Approach, and Visual Outcomes by Ana Sofia Lopes, Rita Basto, Susana Henriques, Luísa Colaço, Filomena Costa e Silva, Isabel Prieto, Francisco Guerreiro

“…Results. Arterial hypertension was the most prevalent systemic risk factor (53.8%). …”
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New-onset gastrointestinal disorders in COVID-19 patients 3.5 years post-infection in the inner-city population in the Bronx by Sagar Changela, Samad Ashraf, Justin Y. Lu, Kevin E. Duong, Sonya Henry, Stephen H. Wang, Tim Q. Duong

“…COVID-19 patients had an elevated risk of developing new GID (adjusted HR = 1.18 (95% CI 1.12–1.25) compared to propensity-matched controls, after adjusting for confounders that included smoking, obesity, diabetes, hypertension. These findings underscore the need for additional research and follow-up of at-risk individuals for developing GID post infection.…”
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Uncoded chronic kidney disease prevalence in secondary care: a retrospective audit with population health implications by Samantha Dolan, Ajitesh Anand, Philip A. Kalra, Stuart Stewart

“…Conversion of uncoded to coded CKD at discharge was only 6.7%. Hypertension and advanced CKD were significant predictors of coding CKD on discharge in uncoded patients. …”
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The Renal and Liver Complications Development among Patients with Type 2 Diabetes Mellitus in Kirkuk City by Wasan Talib Abed, Walaa Esmael Jassim, Emad Mohamed Rasheed

“…The hospital-based cases- control study was conducted for patients with T2DM patients that attended the diabetic clinics in Kirkuk during the period from March 2021– to August 2021 and were screened for serum conc. of liver function tests (Alanine Aminotransferase (ALT), Aspartate Aminotransferase (AST) and Alkaline Phosphatase (ALP)), renal function tests (Creatinine and Urea) especially with (family history of diabetes, & hypertension.  Patients recruited for this study, showed serum urea and creatinine significantly more than that in control, p < .001, while for renal glomerular filtration rates significantly lower than that in control group, p < 001. …”
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Influence of Artificial Sweetener on Human Blood Glucose Concentration by Ilse Skokan, P. Christian Endler, Beatrix Wulkersdorfer, Dieter Magometschnigg, Heinz Spranger

“…In this pilot-study 16 patients were included suffering from adiposity, pre-diabetes and hypertension. In the sense of a cross-over design, three test trials were performed at intervals of several weeks. …”
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Risk Factors for Macro- and Microvascular Complications among Older Adults with Diagnosed Type 2 Diabetes: Findings from The Irish Longitudinal Study on Ageing by Marsha L. Tracey, Sheena M. McHugh, Anthony P. Fitzgerald, Claire M. Buckley, Ronan J. Canavan, Patricia M. Kearney

“…Diabetes diagnosis of 10 or more years, a history of smoking, and a diagnosis of hypertension were associated with an increased risk of microvascular complications. …”
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Smoking as a causative factor in chronic kidney disease: a two-sample Mendelian randomization study by Yue Yang, Zheng Zhang, Hai-tao Lu, Qian-qian Xu, Li Zhuo, Wen-ge Li

“…Additionally, the effect of smoking on CKD was mediated by factors such as body mass index, cardiovascular disease, hypertension, and type 2 diabetes. These findings identify smoking as a contributing factor to CKD and suggest that reducing smoking prevalence could significantly lower the incidence of CKD in the population.…”
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Uremic Leontiasis Ossea due to Resistant Secondary Hyperparathyroidism by Kubra Tuna, MD, Olesya Ilkun, MD, PhD, Peter T. Dziegielewski, MD, Anu Sharma, MD

“…Case Report: A 48-year-old woman with a history of hypertension, coronary artery disease, and ESRD on hemodialysis presented with severe secondary hyperparathyroidism and calciphylaxis. …”
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A Prospective, Multinational Pharmacoepidemiological Study of Clinical Conversion to Sirolimus Immunosuppression after Renal Transplantation by Bertram L. Kasiske, Bjorn Nashan, Maria Del Carmen Rial, Pablo Raffaele, Graeme Russ, Josep Campistol, Mark D. Pescovitz, Paul A. Keown

“…The most common adverse events were hypertension (47%), hyperlipidemia (26%), urinary tract infections (25%), anaemia (24%) and diarrhea (14%), and cardiac events, hyperlipemia and CMV infection were more common in patients converted during the first year. …”
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The Guyana Diabetes and Foot Care Project: Improved Diabetic Foot Evaluation Reduces Amputation Rates by Two-Thirds in a Lower Middle Income Country by Julia Lowe, R. Gary Sibbald, Nashwah Y. Taha, Gerald Lebovic, Madan Rambaran, Carlos Martin, Indira Bhoj, Brian Ostrow

“…Phase 2: Regionalization to cover 90% of the Guyanese population and expansion to include improved management of diabetes and hypertension. Fourteen key opinion leaders were educated and 340 health care professionals from 97 facilities trained. …”
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Liver lobes and cirrhosis: Diagnostic insights from lobar ratios by Kriti Pandey, Debabrata Dash, Raj Kumar Koiri

“…Cirrhosis primarily causes portal hypertension which has a varying impact on the four lobes. …”
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Epidemiology and risk factors of diabetic retinopathy in upper Egypt: a 3-year prospective study by Hassan S. Yousef, Mohamed E. Ahmed, Esam A. G. Abu El Wafa, Mohamed A. K. Salih

“…Also, DR was significantly associated with insulin use, moderate and poor control of diabetes mellitus, uncontrolled hypertension (HTN), dyslipidemia, and nephropathy (P<0.01 for all). …”
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Acute Kidney Injury in a Case Series of Patients with Confirmed COVID-19 (Coronavirus Disease 2019): Role of Angiotensin-Converting Enzyme 2 and Renin-Angiotensin System Blockade by Avantika Chenna, Venu Madhav Konala, Subhasish Bose, Sasmit Roy, Bhaskar Reddy Madhira, Vijay Gayam, Srikanth Naramala, Sreedhar Adapa

“…The renin-angiotensin system plays a very critical role in hypertension, diabetes, and kidney and heart diseases. …”
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Specialized Medical Weight Management Intervention for High-Risk Obesity by Gitanjali Srivastava, Chelsea Paris, Jessica Johnson, Emma Barnes, Brittany L. Cunningham, C. J. Stimson, Kevin D. Niswender, Sabrina J. Poon

“…The prevalence of any obesity-related medical condition was 54.1%; at least a quarter of the patients had either prediabetes or Type 2 diabetes mellitus, approximately a third had hypertension, and over 8% had hyperlipidemia. Mean weight loss from the initial program start date was 6.28% (+/-0.48% standard error of mean [SEM]; 95% confidence interval [CI] 5.34-7.23%). …”
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