Head and Neck Schwannomas: A Surgical Challenge—A Series of 5 Cases by Ishtyaque Ansari, Ashfaque Ansari, Arjun Antony Graison, Anuradha J. Patil, Hitendra Joshi

“…Schwannomas are always a diagnostic dilemma as they are asymptomatic for long time, and histopathology is the gold standard for diagnosis. As a rule, treatment is surgical and dictated by the location of the tumor and nerve of origin. …”
Get full text

Staining Efficacy of Zingiber Officinale and Curcuma Longa as a Natural Alternative to Eosin - A Comparative Study by Mitul Prajapati, Monali Shah, Amena Ranginwala, Hiren Bhojak, Saurabh Nayak, Prakhar Agarwal

“…Eosin is the widely used synthetic dye in histopathology. Zingiber officinale (ginger) and Curcuma longa (turmeric) contain polyphenolic compounds and several colouring compounds, which impart colour. …”
Get full text

B-Flow Twinkling Sign in Preoperative Evaluation of Cervical Lymph Nodes in Patients with Papillary Thyroid Carcinoma by Giuseppina Napolitano, Antonio Romeo, Andrea Bianco, Maurizio Gasperi, Pio Zeppa, Luca Brunese

“…Of these, 298 were metastatic, according to histopathology. The BFI-TS showed high values ​​of specificity (99.7%) and sensitivity (80.9%). …”
Get full text

A Lifelong Smoker with Hypopituitarism: Rethinking the Hypothesis of a Tumor in the Hypophysis by Nestoras Mathioudakis, Alfredo Quinones-Hinojosa, Roberto Salvatori, Shehzad Basaria

“…Transsphenoidal resection of the tumor was performed and histopathology revealed small cell carcinoma. The patient received chemotherapy, but died 18 months later due to widespread brain metastases. …”
Get full text

Lyophilized B. subtilis ZB183 Spores: 90-Day Repeat Dose Oral (Gavage) Toxicity Study in Wistar Rats by B. Appala Naidu, Kamala Kannan, D. P. Santhosh Kumar, John W. K. Oliver, Zachary D. Abbott

“…There were no test item-related changes observed in haematology, coagulation, urinalysis, thyroid hormonal analysis, terminal fasting body weights, organ weights, gross pathology and histopathology. A minimal increase in the plasma albumin level was observed at 1010 and 1011 CFU/kg/day doses without an increase in total protein in males or females and was considered a nonadverse effect. …”
Get full text

Evaluation of the Potential Prognostic Value of Tumor Budding in Laryngeal Carcinoma by Conventional and Immunohistochemical Staining by Nermine M. Abd Raboh, Ossama M. Mady, Sarah A. Hakim

“…A retrospective study on 118 cases of laryngeal squamous cell carcinoma from archives of Pathology Lab of Ain Shams University Specialized Hospital and Ain Shams University Hospitals from January 2014 to January 2017. The ENT and histopathology reports were reviewed to determine clinicopathologic data of the patients. …”
Get full text

A Pancreatic Head Tumor Arising as a Duodenal GIST: A Case Report and Review of the Literature by Fabian Bormann, Wolfgang Wild, Hüseyin Aksoy, Pius Dörr, Sanja Schmeck, Matthias Schwarzbach

“…The patient underwent pancreatoduodenectomy (PD) modified after Traverso-Longmire, histopathology proved a duodenal GIST. This case proves that duodenal GISTs can grow invasively into the pancreas and appear as solid pancreas head tumor; therefore, these tumors should be included into differential diagnosis.…”
Get full text

A Rare Case of Pneumopericardium in the Setting of Tuberculous Constrictive Pericarditis by Lauro L. Abrahan IV, Stephanie Martha O. Obillos, Jaime Alfonso M. Aherrera, Jose Donato A. Magno, Celia Catherine C. Uy-Agbayani, Ulysses King G. Gopez, Jobelle Joyce Anne R. Baldonado

“…Pericardiectomy was performed as definitive management, with stripped pericardium measuring 5–7 mm thick and caseous material extracted from the pericardial sac. Histopathology was consistent with tuberculosis. This report highlights pneumopericardium as a rare complication of pericardiocentesis. …”
Get full text

Luteolin ameliorates rat model of metabolic syndrome-induced cardiac injury by apoptosis suppression and autophagy promotion via NR4A2/p53 regulation by Xiyan Dai, Bo Liang, Yaolin Sun

“…The animal’s weight, blood pressure, lipid profile, tolerance to glucose and insulin, and cardiac histopathology were evaluated. Moreover, troponin T, creatine kinase-myocardial band (CK-MB), inflammatory profile (IL-6, IL-1β, TNF-α), transforming growth factor-β1 (TGF-β1), oxidative stress, and matrix metalloproteinase-9 (MMP-9) were analyzed to determine the cardiac state. …”
Get full text

Overt Mycobacterium avium subsp. paratuberculosis Infection: An Infrequent Occurrence in Archived Tissue from False TB Reactor Cattle in Michigan, USA by Scott D. Fitzgerald, Steven R. Bolin, Kathryn G. Boland, Ailam Lim, John B. Kaneene

“…Retrospective analysis of formalin-fixed, paraffin-embedded sections of ileum and ileocecal lymph node were evaluated by histopathology, acid-fast staining, and PCR assays to detect MAP. …”
Get full text

The protective effect of coadministration of coenzyme Q10 and vitamin E on myopathy induced by simvastatin in rats by Omar Ammar Hashim, Intesar Tarik Numan, Nadia Hameed Mohammed

“…In addition, gastrocnemius muscle histopathology was examined. Treatment with CoQ10, vitamin E, or their combination significantly reduced the levels of CKM, aldolase, iNO2, and MDA and increased TAOC compared to the simvastatin induction group. …”
Get full text

Uterine Sarcoidosis: A Rare Extrapulmonary Site of Sarcoidosis by Creticus P. Marak, Narendrakumar Alappan, Amit Chopra, Olena Dorokhova, Sumita Sinha, Achuta K. Guddati

“…In this case report, the clinical presentation, histopathology, clinical course, and treatment of a patient with isolated uterine sarcoidosis are described, and a brief literature review of sarcoidosis of the female genital tract is provided.…”
Get full text

Performance of Vasopressin Stimulated Bilateral Inferior Petrosal Sinus Sampling in Corticotropin Dependent Cushing’s Syndrome with Negative or Equivocal 3 Tesla Contrast Enhanced... by Puneet Shivnani, Rajeev Kasliwal, Gourav Goyal, Jyoti Sharma, Utkarsh Balani, Pankaj Gupta, Bhawani S. Sharma, Dinesh Yadav, Vineet Mishra, Surendra K. Sharma

“…Results: Of seventeen patients who underwent BIPSS, nine patients had a raised central-to-peripheral ACTH ratio and were classified as having CD that was confirmed on histopathology following transsphenoidal sinus surgery. …”
Get full text

Upper Gastrointestinal Crohn’s Disease: Literature Review and Case Presentation by Soorya N. Aggarwal, Yana Cavanagh, Lan Wang, Amer Akmal, Matthew A. Grossman

“…Grossly cobblestoned mucosa along with histopathology revealing focal crypt abscesses, chronic inflammation in the lamina propria, and superficial foveolar epithelial regenerative changes were consistent with CD. …”
Get full text

Ascorbic acid alleviates reproductive toxicity of di-(2-ethyl hexyl) phthalate in female Wistar rats by Kalaivani Manokaran, Ravi Sankar Bhaskaran, Jayesh Mudgal, Prabu Paramasivam, Sachin Shetty, Deepak Nayak, Sunitha Carnelio, Vennila Jaganathan, Dharani Abirama Sundari Shanmugam, Karkala Sreedhara Ranganath Pai

“…Co-treatment with ascorbic acid significantly improved these parameters, reducing oxidative stress and apoptosis, and restoring hormone levels and gonadotropin receptor expression. Histopathology revealed fewer atretic follicles and less disruption in ovarian structure in DEHP and ascorbic acid-treated groups compared to those treated with DEHP alone. …”
Get full text

Prevention of LPS-Induced Acute Lung Injury in Mice by Progranulin by Zhongliang Guo, Qinchuan Li, Yang Han, Yongjie Liang, Zengguang Xu, Tao Ren

“…Consistently, we revealed a significant reduction of histopathology changes of lung in mice received PGRN treatment. …”
Get full text

Reaction of the Liver upon Long-Term Treatment of Fluoxetine and Atorvastatin Compared with Alcohol in a Mouse Model by Zhiliang Chen, Tony C. H. Chow, Shicong Wang, Gigi C. T. Leung, Sharon L. Y. Wu, David T. Yew

“…Comparisons of animals treated with the three drugs were carried out: serum aspartate transaminase (AST), alanine transaminase (ALT), and albumin were measured; liver tumor necrosis factor alpha (TNF alpha) and transforming growth factor beta (TGF beta-1) levels were evaluated; proliferative cells were detected via immunohistochemistry (IHC) targeting on proliferating cell nuclear antigen (PCNA) and minichromosome maintenance complex component 2 (MCM2); for apoptosis, IHC targeting on activated caspase-3 and terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) were employed; and histopathology was also documented in all groups. Results. …”
Get full text

Glioblastoma with Both Oligodendroglioma and Primitive Neuroectodermal Tumor-Like Components in a Case with 9-Year Survival by Ying-Tso Chen, Shu-Shong Hsu, Chi-Man Yip, Ping-Hong Lai, Huai-Pao Lee

“…She underwent the first craniectomy for tumor removal, and histopathology revealed classic GBM. Tumor recurrence occurred 8 years later. …”
Get full text

Evaluation of Serum Bilirubin as a Predictive Marker for Simple and Complicated Appendicitis in Sulaimani Emergency Teaching Hospital by Seerwan Hama Shareef, Dara Ahmed Mohammed, Goran Ameer Ahmed

“…Preoperative total serum bilirubin was measured and compared with the final histopathology report. Patients were divided into 3 groups: non-inflamed appendix, simple appendicitis and complicated appendicitis. …”
Get full text

Diagnostic Difficulties of Erosive Lichen Planus in a Pediatric Patient by Carolyn Szwed, Olivia Gudziewski, Marta Sar-Pomian, Malgorzata Olszewska, Lidia Rudnicka, Joanna Czuwara

“…Laboratory tests did not reveal any abnormalities. Histopathological examination of the tongue lesions was representative of ELP. …”
Get full text