Explore Alteration of Lung and Gut Microbiota in a Murine Model of OVA-Induced Asthma Treated by CpG Oligodeoxynucleotides by Wang Q, Ji J, Xiao S, Wang J, Yan X, Fang L

“…High-throughput sequencing technology targeting 16S rRNA was employed to analyze the composition, diversity, and correlation of microbiome in the lung, colon and small intestine of control, model and CpG-ODN administration groups.Results: (1) Histopathologically, both lung and intestinal tissue in asthmatic mice exhibited significant structural damage and inflammatory response, whereas the structure of both lung and intestinal tissue approached normal levels, accompanied by a notable improvement in the inflammatory response after CpG-ODN treatment. (2) In the specific microbiota composition analysis, bacterial dysbiosis observed in the asthmatic mice, accompanied by enrichment of Proteobacteria found to cause lung and intestinal epithelial damage and inflammatory reaction. …”
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Serum Levels of SDF-1 and CXCR4 in Breast Cancer: Correlation with Disease Progression and Chemotherapy Response in Iraqi Women by Noor Al Rubaiey, Hazima ALabassi

“…Diagnosis was confirmed through mammography and histopathological examination. Blood samples (3 ml) were collected, processed, and stored for analysis, with serum levels of SDF1 and CXCR4 measured using ELISA kits.The study revealed that SDF1 levels were significantly elevated in newly diagnosed patients (84.91 ± 4.2 pg/ml) compared to chemotherapy patients (59.94 ± 2.18 pg/ml) and controls (57.00 ± 3.47 pg/ml), with p≤0.001. …”
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Single-Cell RNA Sequencing Analysis of Steroidogenesis and Spermatogenesis Impairment in the Testis of db/db Mice by Yun Hu, Ting-Ting Cai, Reng-Na Yan, Bing-Li Liu, Bo Ding, Jian-Hua Ma

“…The differentially expressed genes were then confirmed by real-time PCR. The histopathological characteristics of testis in db/db mice and C57BL/6J control were also performed. …”
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Abdominal Aortic Occlusion and the Inflammatory Effects in Heart and Brain by Jun Xu, Sijie Li, Alexandra Wehbe, Xunming Ji, Yong Yang, Yu Yang, Linhui Qin, Feng-Yong Liu, Yuchuan Ding, Changhong Ren

“…Serum, hippocampus, and left ventricle tissue samples were then subjected to biochemical and histopathological analyses. Results. AAO-induced I/R injury had no effect on cell necrosis, cell apoptosis, or ROS production. …”
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Neuroprotective Effects of the Ethanolic Leaf Extract of Crassocephalum crepidioides (Asteracaeae) on Diazepam-Induced Amnesia in Mice by Beppe Galba Jean, Folefack Alice Irène, Atsamo Albert Donatien, Ngatanko Aïbassou Hervé-Hervé, Barga Mpoo Bertrand, Allah-Doum Nanou Gael, Nguedia Ymele Merline, Zemo Gamo Franklik, Dongmo Alain Bertrand, Dimo Théophile

“…Moreover, compared to the negative control group, the extract significantly (p<0.01) increased superoxide dismutase activity and significantly (p<0.01) decreased malondialdehyde levels. The histopathological analysis of hippocampi showed that the cc extract increased cell density when compared with the negative control. …”
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Hypolipidemic effect of coffee silver skin in rats fed a high-fat diet by Ayman Mohammed El-Anany, Rehab Farouk M. Ali

“…The lipid parameter of the serum was recorded and liver and kidney function tests were conducted. Finally, a histopathological assay was performed on the liver and kidney tissues of the rats fed the tested diets. …”
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Saffron's protective role against atherosclerosis-induced cataract progression in New Zealand white rabbits with phytochemical analysis of saffron's extract. by Yasmin Mohd Zainal Abidin Shukri, Iman Nabilah Abd Rahim, Nurul Alimah Abdul Nasir, Che Puteh Osman, Noor Alicezah Mohd Kasim

“…After completing the 16-week experimental protocol, the NZWR were euthanized, and their lenses were extracted for histopathological evaluation. The pre-treated group exhibited cataractous lens changes of grade 2, characterized by increased homogenisation, swollen lens fibers, and intracellular vacuolisation. …”
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Radiomics for differentiating adenocarcinoma and squamous cell carcinoma in non-small cell lung cancer beyond nodule morphology in chest CT by Minmini Selvam, Abjasree Sadanandan, Anupama Chandrasekharan, Sidharth Ramesh, Arunan Murali, Ganapathy Krishnamurthi

“…We studied individuals with histopathologically proven adenocarcinoma or SCC type NSCLC tumours, detected as lung nodules on Chest CT. …”
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Challenges in the Management of Giant Carcinoma Ex-Pleiomorphic Adenoma of the Parotid Gland in a Single Tertiary Center by Miruna Bratiloveanu, Mihai Dumitru, Andreea Nicoleta Marinescu, Crenguta Serboiu, Oana Maria Patrascu, Adrian Costache, Daniela Vrinceanu

“…The reasons for presenting to our department included a sudden increase in size in eleven cases (78.57%), pain in nine cases (64.29%), peripheral facial paralysis in eight cases (57.14%), skin invasion/ulceration in five cases (35.71%), and massive tumor hemorrhage in one case (7.14%). There were histopathological results on paraffin of myoepithelial CXPA in four cases (28.57%), of high-grade CXPA (salivary duct, secretory) in eight cases (57.14%), and of squamous CXPA in two cases (14.29%). …”
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Pulmonary Nuclear protein in Testis (NUT) carcinoma: clinical, molecular characteristics, and treatment strategies by Jingjing Qu, Zhen Chen, Yanping Zhu, JinYan Huang, Qian Shen

“…Comprehensive clinical, imaging, histopathological, and molecular data and survival outcomes were collected. …”
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Therapeutic Effects of the Combination of Alpha-Lipoic Acid (ALA) and Coenzyme Q10 (CoQ10) on Cisplatin-Induced Nephrotoxicity by Eman Aly Khalifa, Ahmed Nabil Ahmed, Khalid Shaaban Hashem, Ahmad Gad Allah

“…Renal functions, tissue antioxidant activity, and inflammatory markers (tumor necrosis factor, TNF) were estimated along with histopathological study. Results. Renal function tests and urinary proteins were significantly higher within group II compared with other groups (P value <0.001). …”
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Deletion of pagL and arnT genes involved in LPS structure and charge modulation in the Salmonella genome confer reduced endotoxicity and retained efficient protection against wild-... by Ram Prasad Aganja, Jun Kwon, Amal Senevirathne, John Hwa Lee

“…However, the immunisation significantly increased antigen-specific IgY, sIgA secretion, and CD4+ and CD8+ T-cell responses while inducing lower pro-inflammatory cytokine levels than SG9R. Histopathological evaluations revealed substantial protection in the immunised birds, with minimal tissue damage and inflammatory responses, thus reducing the in vivo bacterial burden. …”
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The Oncogenic Human Papillomavirus Involvement as a Risk Factor of Measles, Mumps, and Rubella Vaccine Immunotherapy Failure in Anogenital Warts by Achdiat PA, Ismiranty D, Hindritiani R, Rizqandaru T, Usman HA, Maharani RH

“…Dermatological examination showed that the pubic region and penile shaft presented 51 verrucous papules for 6 months, with histopathological results supporting the diagnosis of AGW. …”
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Rauwolfia vomitoria- a promising medical plant for benign prostatic hyperplasia management; yet with challenges by George Awuku Asare, Perpetua Dagadu, Samuel Adjei, Bernice Asiedu, Samkeliso Takaidza, Vivash Naidoo, Brodrick Amoah, Ifeoma Celestina Orabueze, Kwasi Bugyei

“…Systemic organs and the prostate were harvested for histological analyses. Result: Histopathological analysis of the liver of RVARE treated groups demonstrated alterations. …”
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Complications after autologous fat grafted into residual capsular sac after removal of breast prosthesis: Case reports by Ting Li, Yi Sun, Sufan Wu, Ce Zhang

“…In another patient, upon dissecting the capsular sac, a fibrocystic mass containing necrotic adipose tissue was observed. Histopathological analysis of the fibro-oil cysts and the fibrocystic mass revealed that the surrounding envelope consisted of fibrous cystic parietal tissue enclosing pale and mildly lipid necrotic tissue. …”
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Cytokine Profile in Early Infection by Leptospira interrogans in A/J Mice by Lorena Bavia, Íris A. de Castro, Mariane Tami Amano, Ana Maria Gonçalves da Silva, Silvio Arruda Vasconcellos, Lourdes Isaac

“…Although both mouse strains developed splenomegaly, similar histopathological alterations in the liver and the lung, levels of pro- and anti-inflammatory cytokines were different. …”
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Efficacy of umbilical cord-derived mesenchymal stem cells and exosomes in conjunction with standard IBD drug on immune responses in an IBD mouse model by Fatemeh Kheradmand, Seyedeh Fatemeh Yasaman Rahimzadeh, Seyed-Alireza Esmaeili, Sajad Sahab Negah, Najmeh Kaffash Farkhad, Seyedeh Elnaz Nazari, Mehrdad Hajinejad, Mohammad Ali Khodadoust, Afsane Fadaee, Jalil Tavakol Afshari, Majid Khazaei

“…Furthermore, colon tissue was stained to investigate histopathological changes. Results In the groups that received MSCs, there was a significant reduction in the disease activity index and their combinations with exosomes and Mesalazine compared to the colitis group. …”
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Real-world data on utilization of neoadjuvant chemotherapy for muscle invasive bladder cancer: impact on surgical complications and oncological efficacy by Hege S. Haugnes, Hakon Kjaeve, Eivind Bjerkaas, Ragnhild Hellesnes, Line Hjelle, Magnus Larsen

“…Complications after cystectomy (Clavien-Dindo ≥ grade 3 within 30 days), histopathologic NAC response, cancer recurrence, relapse-free survival (RFS), overall survival (OS) and cause of death were reported. …”
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Automatic Characterization of Prostate Suspect Lesions on T2-Weighted Image Acquisitions Using Texture Features and Machine-Learning Methods: A Pilot Study by Teodora Telecan, Cosmin Caraiani, Bianca Boca, Roxana Sipos-Lascu, Laura Diosan, Zoltan Balint, Raluca Maria Hendea, Iulia Andras, Nicolae Crisan, Monica Lupsor-Platon

“…Multiparametric magnetic resonance imaging (mpMRI) holds a central role in PCa assessment; however, it does not have a one-to-one correspondence with the histopathological grading of tumors. Recently, artificial intelligence (AI)-based algorithms and textural analysis, a subdivision of radiomics, have shown potential in bridging this gap. …”
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Exosomes derived from hUC-MSCs exhibit ameliorative efficacy upon previous cesarean scar defect via orchestrating β-TrCP/CHK1 axis by Xiaoling Zeng, Yuan Liao, Dan Huang, Jing Yang, Zhihua Dai, Zhengyong Chen, Xin Luo, Han Gong, Shengwen Huang, Leisheng Zhang

“…On the other hand, with the aid of CHK1 overexpression and β-TrCP knockdown, together with multifaceted biological analyses (e.g., histopathological sections, qRT-PCR assay, western-blotting analysis, Co-IP assay, protein degradation and ubiquitination), we further dissected the underlying regulatory mechanism. …”
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