Exploration of the anti-inflammatory potential of Polygonum bistorta L.: protection against LPS-induced acute lung injury in rats via NF-ĸβ pathway inhibition by Sajida Parveen, Kashif ur Rehman Khan, Shahid Muhammad Iqbal, Hanan Y. Aati, Areej M. Al-taweel, Liaqat Hussain, Musaddique Hussain, Musaddique Hussain

“…Plant extract markedly restored LPS-induced hypoxemia, pulmonary edema, histopathological alterations, and leukocyte infiltration in the lung. …”
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Collapsing Pattern Class-IV Lupus Nephritis Presenting as Posterior Reversible Encephalopathy Syndrome and Cardiac Tamponade: A Rare COVID-19 Sequelae by K Harshitha Reddy, Pranjal Kashiv, Sunil Kumar, Sourya Acharya, Kapil Navin Sejpal

“…The collapsing variety of FSGS (cFSGS) is defined histopathologically by segmental or global glomerular capillary condensation and obliteration, the appearance of hyperplastic and hypertrophic podocytes, and substantial tubulointerstitial damage. …”
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Study on the Role and Pathological and Immune Responses of Silver Nanoparticles Against Two <i>Aeromonas salmonicida</i> subsp. <i>salmonicida</i> Strains at Different Virulence Le... by Yunqiang Guo, Chaoli Zheng, Yingfei Wang, Yongji Dang, Ruiyuan Li, Ye Tao, Yucheng Yang, Xiaofeng Sun, Zekun Song, Pengcheng Sun, Qian Zhang, Dandan Qian, Wenhao Ren, Xiyu Cao, Bowen Wang, Mengxi Xu, Bingyang Jiang, Yujing Li, Qing Sun, Jinye Wang, Lei Zheng, Yanling Sun

“…<i>salmonicida</i> strains (I-1 and I-4), isolated from rainbow trout; the antibacterial mechanism, histopathological alterations and the expression of immune-related genes were investigated. …”
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Unveiling the potential anticancer activity of Spirulina maxima extract-nanoemulsion through in vitro and in vivo studies by Mohammed Yasser Hussein, Merna Nasr, Veronia Emad, Julie Maged, Portia George, Amina Emad, Abeer Mahmoud Badr, Mehrez E. El-Naggar, Sayeda M. Abdo, Jihan Hussein

“…SMNE also demonstrated efficacy in inhibiting tumor growth in mice with Ehrlich ascites carcinoma, normalizing alanine aminotransferase (ALT) and aspartate aminotransferase (AST) levels, and reducing oxidative stress markers such as catalase (CAT) and malondialdehyde (MDA). Histopathological examination showed that SMNEC3-treated groups had almost normal liver architecture. …”
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Expression of IGF-1R in oral submucous fibrosis and oral squamous cell carcinoma – An RT-PCR study by Vivek Nayyar, Vinay Hazarey, Sindhu M. Ganvir, Hemant J. Purohit, Reshma Talkal, Kiran Jot

“…Materials and methods: Thirty biopsy tissue samples for each of the three groups, NOM, OSMF, and OSCC, were taken and analyzed histopathologically and then subjected to RT-PCR for evaluation of the expression of IGF-1R mRNA in each of them. …”
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Compound exposure of 2.8 GHz and 9.3 GHz microwave causes learning and memory impairment in rats by Liu Sun, Xiaoya Wang, Ke Ren, Chuanfu Yao, Haoyu Wang, Xinping Xu, Hui Wang, Ji Dong, Jing Zhang, Binwei Yao, Xiaohui Wei, Ruiyun Peng, Li Zhao

“…Moreover, microwave also could induce abnormal electroencephalogram (EEG), such as increasing the power of θ wave and δ wave, suggesting brain damage or dysfunction. Histopathological analysis suggested that microwave resulted in obvious structural injuries in hippocampus at 7 d after exposure, and most serious injuries were observed in compound microwave exposed rats. …”
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Investigation of the Effects of Fosfomycin in Kidney Damage Caused by CLP-Induced Sepsis by Ilknur Esen Yildiz, Tolga Mercantepe, Ilkay Bahceci, Medeni Arpa, Sule Batcik, Yasin Yildiz, Levent Tumkaya

“…The effects of fosfomycin on kidney function, histopathological changes, inflammatory markers, oxidative stress, and apoptosis were assessed. …”
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The critical role of MLKL in hemorrhagic stroke and the therapeutic potential of its associated protein network by Yi Wang, Yi Wang, Moran Xu, Xiaoli Zuo, Sheng Wang, Yong Yu, Zhaobing Gao, Zhaobing Gao, Jingbo Qie, Ye Jiang, Fang Huang, Bingqing Xia, Bingqing Xia

“…However, the mechanisms by which MLKL functions in the process of intracerebral hemorrhage (ICH)-induced damage remain unclear.MethodsHere, we explored the correlation between MLKL and pathological damage in ICH patients through histopathological staining and RT-qPCR. Furthermore, we established an intracerebral hemorrhage model by collagenase IV injection in WT and Mlkl-/- mice. …”
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Study protocol for a randomised controlled trial on the use of intraoperative ultrasound-guided laparoscopic ovarian cystectomy (UGLOC) as a method of fertility preservation in the... by Srdjan Saso, Sadaf Ghaem-Maghami, Jan Yvan Jos Verbakel, Benjamin P Jones, Joseph Yazbek, Mona El-Bahrawy, Lorraine S Kasaven

“…Secondary outcomes include assessment of various surgical and histopathological findings, including duration of hospital stay (days), duration of surgery (minutes), presence of intraoperative cyst rupture (yes/no), presence of ovarian tissue within the resected specimen (yes/no) and the grade of follicles excised within the specimen (grade 0–4). …”
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Osimertinib exacerbates immune checkpoint inhibitor-related severe adverse events by activating the IL-6/JAK/STAT3 pathway in macrophages by Yuan Li, Yanping Chen, Yuan Meng, Meng Shen, Fan Yang, Xiubao Ren

“…Hematoxylin-eosin staining was used to analyze the histopathologic inflammatory infiltration in mouse liver and lung tissues. …”
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The Comparison of Diagnostic Ability between Blue Laser/Light Imaging and Narrowband Imaging for Sessile Serrated Lesions with or without Dysplasia by Reo Kobayashi, Naohisa Yoshida, Yukiko Morinaga, Hikaru Hashimoto, Yuri Tomita, Satoshi Sugino, Ken Inoue, Ryohei Hirose, Osamu Dohi, Takaaki Murakami, Yutaka Inada, Yasutaka Morimoto, Yoshito Itoh

“…This was a subgroup analysis of prospective studies. 476 suspiciously serrated lesions of ≥2 mm on the proximal colon showing serrated change with magnified NBI or BLI in our institution between 2014 and 2021 were examined histopathologically. After propensity score matching, we evaluated the diagnostic ability of SSL and SSLD of the NBI and BLI groups regarding various endoscopic findings. …”
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Ibuprofen-Induced Multiple Fixed Drug Eruption Confirmed by Re-Challenge: A Case Report and Literature Review by Yoshihito Mima, Masako Yamamoto, Hiyo Obikane, Yuta Norimatsu, Ken Iozumi

“…The diagnosis was confirmed by detecting a rash immediately following ibuprofen administration, and histopathological findings were consistent with FDE. Ibuprofen is widely available as an over-the-counter medication, and patients may not always report its use—making the diagnosis of ibuprofen-induced FDE particularly challenging. …”
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Clinical outcomes of dogs with high-grade cutaneous mast cell tumors by Siew Mei Ong, Siew Mei Ong, Charly McKenna, Christopher Pinard, Christopher Pinard, Christopher Pinard, Christopher Pinard, Danielle Richardson, Michelle L. Oblak

“…ObjectivesTo evaluate the prognostic factors and treatment outcomes in dogs with high-grade cutaneous mast cell tumors (HGMCTs).MethodsMedical records of dogs with a histopathologic diagnosis of HGMCTs were reviewed from a single institution. …”
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Protective Role of Genistein in Acute Liver Damage Induced by Carbon Tetrachloride by Nalan Kuzu, Kerem Metin, Adile Ferda Dagli, Fatih Akdemir, Cemal Orhan, Mehmet Yalniz, Ibrahim Hanifi Ozercan, Kazim Sahin, Ibrahim Halil Bahcecioglu

“…Plasma and liver tissue malondialdehyde (MDA) and liver glutathione levels, as well as AST and ALT levels were studied. A histopathological examination was conducted. Results. Liver tissue MDA levels were found significantly lower in group 3, in comparison to group 2 (P<.05). …”
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Complete blood count parameters and inflammation-related biomarkers in patients with colorectal carcinoma by Koržinek Martha, Ćelap Ivana, Fabijanec Marija, Žanić Tena, Ljubičić Neven, Baršić Neven, Verbanac Donatella, Barišić Karmela, Rajković Marija Grdić

“…The study included 155 patients who were divided into two groups according to histopathological analysis – 74 adenomas patients and 81 CRC patients. …”
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Rutin via Increase in the CA3 Diameter of the Hippocampus Exerted Antidepressant-Like Effect in Mouse Model of Maternal Separation Stress: Possible Involvement of NMDA Receptors by Maryam Anjomshoa, Shakiba Nasiri Boroujeni, Sorayya Ghasemi, Zahra Lorigooini, Ahmad Amiri, Shima Balali-dehkordi, Hossein Amini-khoei

“…Afterwards, the hippocampus was evaluated in cases of histopathological changes as well as expression of NR2A and NR2B genes. …”
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Gallic acid alleviates exercise-induced muscle damage by inhibiting mitochondrial oxidative stress and ferroptosis by Likai Yu, Di Tian, Zishan Su, Li Zhang, Shaobo Guo, Wenhui Zhu, Yuan Fang, Peimin Wang, Nongshan Zhang

“…Methods We first established a skeletal muscle injury model caused by excessive exercise. Histopathological analysis was used to determine the severity of skeletal muscle injury in mice. …”
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Proximal bronchiolar adenoma with malignant transformation to invasive mucinous adenocarcinoma with 4 years follow-up: a case report and literature review by Yuan-Hui Yang, Ke Yin, Jia-Qi Xu, Xiao-Ying Xu, Jun-Lei Zhang, Ji-Xuan Liu, Xin-Zhi Feng, Xiao-Yan Lin, Xiao-Yan Lin

“…The most prominent histopathological feature of BA is a double-layer bronchial epithelium containing continuous basal cell layers. …”
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Highly pathogenic bovine viral diarrhea virus BJ-11 unveils genetic evolution related to virulence in calves by Yuanyuan Zhang, Yuanyuan Zhang, Jing Cheng, Yu Guo, Yu Guo, Yibin Hu, Yibin Hu, Zhuo Zhao, Wenxiao Liu, Linyi Zhou, Peize Wu, Chunjie Cheng, Chunjie Cheng, Chun Yang, Chun Yang, Jing Yang, Jing Yang, Enqi Du, Yongqing Li, Yongqing Li

“…A marked reduction in leukocyte and lymphocyte counts were observed, accompanied by an increase in neutrophil counts. Histopathological changes manifested as severe lung lesions. …”
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Oscillatory ventilation enhances oxygenation and reduces inflammation in an animal model of acute respiratory distress syndrome: an experimental study by Luiz Alberto Forgiarini Junior, Luiz Felipe Forgiarini, Arthur de Oliveira Paludo, Rodrigo Mariano, Mikael Marcelo de Moraes, Elaine Aparecida Felix, Cristiano Feijó Andrade

“…The BiPEEP group showed less changes in histopathological patterns. Conclusion: Variable ventilation with bi-oscillatory level of PEEP demonstrated a potential ventilatory strategy for lung protection in an experimental model of ARDS.…”
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