C9orf72 Alleviates DSS‑Induced Ulcerative Colitis via the cGAS‐STING Pathway by Yue Wang, Ting Xu, Wenjun Wang

“…Caco‐2 cells were cultured to establish C9orf723 overexpressed model. Histopathological examination, level of inflammation, cGAS‐STING pathway, and gut barrier function were detected in mice and cells. …”
Get full text

Evaluation of Feulgen Reaction for Quantitative DNA Analysis in Oral Leukoplakia: Insights into Malignant Transformation Risk by Amit Kumar Srivastava, Ruchi Jain, Aishwarya Srivastava, Swati Shrivastava

“…Statistical analysis was performed to assess the correlation between DNA content and the histopathological grading of the lesions. Results: Out of the 50 samples, 30% (n = 15) exhibited diploid DNA content, 50% (n = 25) were aneuploid, and 20% (n = 10) were tetraploid. …”
Get full text

Protective Effects of Garlic and Cinnamon Oils on Hepatocellular Carcinoma in Albino Rats by Salah M. Aly, Hamdy A. Fetaih, Abeer A. I. Hassanin, Mosleh M. Abomughaid, Aliaa A. Ismail

“…The HCC-induced group showed histopathological features of liver cancer including hypercellularity, nuclear hyperchromasia, mitotic figures, and preneoplastic foci. …”
Get full text

Lymphomatoid Papulosis Type E With T-Cell Receptor Gamma Positivity by Namasondhi A, Rutnin S, Jerasutus S, Boonsakan P, Triyangkulsri K

“…The diagnosis of LyP is mainly based on clinical presentation and histopathological correlation. Six subtypes of LyP have been described and recognized, each with different histological features and sometimes distinct clinical presentations. …”
Get full text

The impact of absorbable hemostatic agents on wound healing in an experimental penile fracture rat model by Mehmet Ezer, Engin Doğantekin, Muzaffer Çaydere, Aykut Koç, Çağrı Öktem, Sema Hücümenoğlu

“…A penile fracture model was created in all rats, and wound healing was assessed histopathologically after two weeks. Key parameters assessed included primary healing, fibrosis, inflammation, and cavernous tissue healing. …”
Get full text

GIANT CELL TUMOR OF THE RIBS: A CASE REPORT by I Putu Gede Pradnyadewa Pradana, Mouli Edward

“…The patient had resection surgery of the lesion. The histopathologic results on the operative specimens confirmed the diagnosis of GCT. …”
Get full text

Toxicopathological Effects of the Venom of Echis ocellatus on Experimentally Envenomated Swiss Albino Rats by P. O. Yusuf, D. Ada, D. B. Nuhu, S. Dahiru, P. M. Ameh, M. Mamman, M. U. Kawu, M. Bisallah, S. J. Enam

“…The vital organs were collected and examined histopathologically. The data revealed necrosis and congestion in the heart tissues of envenomated rats compared to the control group. …”
Get full text

Thyroid Nodules Located in the Lower Pole Have a Higher Risk of Malignancy than Located in the Isthmus: A Single-Center Experience by Gulhan Duman, Baris Sariakcali

“…Ultrasonography provides very valuable information in the evaluation of TNs, but it does not correlate perfectly with histopathologic findings. Therefore, studies that will include new diagnostic methods that can improve these unknowns can be welcomed gratefully. …”
Get full text

A Case of Neuromyelitis Optica: Puerto Rican Woman with an Increased Time Lag to Diagnosis and a High Response to Eculizumab Therapy by Ramón Vega, Benjamín González, Kiara Ortiz, Viviana Martínez, David Carmona, Ivonne Vicente, Javier Chapa, Ángel Chinea

“…This case illustrates the efficacy of eculizumab therapy and the importance of differentiating the clinical, histopathological, and neuroimaging characteristics that separate demyelinating autoimmune inflammatory disorders, such as NMOSD and multiple sclerosis (MS).…”
Get full text

Long-Term Survival of More than 5 Years with Maintenance Therapy Using Single-Agent Pemetrexed in a Patient with Diffuse Malignant Peritoneal Mesothelioma by Yasuo Otsuka, Yoriaki Komeda, Masayuki Takeda, Takayuki Takahama, Masashi Kono, Mamoru Takenaka, Satoru Hagiwara, Naoshi Nishida, Hiroshi Kashida, Masatoshi Kudo

“…In addition, ascites and nodules were observed in the abdominal cavity. Histopathological examination of a biopsy specimen revealed peritoneal invasion of atypical epithelioid cells with trabecular and glandular patterns. …”
Get full text

The efficacy of virtual reality in adults during puncture biopsy: A protocol of a systematic review and meta-analysis. by Xueling Qiu, Lukun Sun, Lu Tang, Xiaochen Jiang, Weifeng Wang, Fan Sun, Chenxi Sun, Tianyi Song

“…<h4>Background</h4>Puncture biopsy is a primary method for obtaining tissue or cell samples from tumors for histopathological diagnosis. However, patients often experience pain, anxiety, and discomfort during the procedure. …”
Get full text

Evaluation of the Diagnostic Performance of Physical Examination Combined with Transvaginal Ultrasonography in Patients with Endometriosis by Talha Tiryaki, Tolga Karacan, Seyma Yesiralioglu, Eser Ozyurek, Huseyin Kiyak, Engin Oral

“…Results: The number of patients reported to have endometriosis histopathologically was 138;132 were in the premenopausal period (symptomatic group n=101, asymptomatic group n=31) and 6 were in the postmenopausal period (symptomatic group n=1, asymptomatic group n=5). …”
Get full text

Etoricoxib–NLC Mitigates Radiation-Induced Ovarian Damage in Rats: Insights into Pro-Inflammatory Cytokines, Antioxidant Activity, and Hormonal Responses by Sahar Khateeb

“…Twenty-four female rats were randomly assigned to four groups: a control group receiving normal saline, a group exposed to a single dose of whole-body gamma radiation (6 Gy), a group treated with etoricoxib (10 mg/kg) post-radiation, and a group treated with ETO-NLC for 14 days following radiation. Histopathological evaluations and oxidative stress biomarker assessments were conducted, including ELISAs for reactive oxygen species (ROS), pro-inflammatory cytokines (IL-1β, TNF-α), and signaling molecules (PI3K, AKT, P38MAPK, AMH). …”
Get full text

Protective Effect of Hydroalcoholic Extract of Stachys pilifera on Oxidant-Antioxidant Status in Renal Ischemia/Reperfusion Injuries in Male Rats by Zahra Moslemi, Izadpanah Gheitasi, Amir Hossein Doustimotlagh

“…However, in agreement with renal function tests, SP extract had no significant effects on histopathological examinations. Conclusion. It seems that SP extract employs renoprotective effects on renal damage induced by I/R, possibly by improving of oxidant-antioxidant status in favor of the antioxidant system.…”
Get full text

Toxicopathological Effects of the Venom of Echis ocellatus on Experimentally Envenomated Swiss Albino Rats by P. O. Yusuf, G. Ada, D. B. Nuhu, S. Dahiru, P. M. Ameh, M. Mamman, M. U. Kawu, M. Bisallah, S. J. Enam

“…The vital organs were collected and examined histopathologically. The data revealed necrosis and congestion in the heart tissues of envenomated rats compared to the control group. …”
Get full text

Two Rare Cases of Feline Toxic Epidermal Necrolysis: A Novel Therapeutic Approach With Medical-Grade Honey by Alexandra Peteoacă, Niels A. J. Cremers, Linsey J. F. Peters

“…TEN was confirmed via histopathological examination. The suspected cause of TEN in both cases was the iodine present in the surgical scrub. …”
Get full text

Homoharringtonine Attenuates Dextran Sulfate Sodium-Induced Colitis by Inhibiting NF-κB Signaling by Jiangrui Liu, Liangpan Shi, Wenchang Huang, Zhihua Zheng, Xiaohui Huang, Yibin Su

“…Body weight, colon length, disease activity index (DAI), and histopathological change were examined. The relative contents of interleukin- (IL-) 1β, tumor necrosis factor- (TNF-) α, IL-6, and the chemokine (C-C motif) ligand 2 (CCL2) in the colon tissues and HHT-treated RAW264.7 cells were detected with the enzyme-linked immunosorbent assay. …”
Get full text

Corrigendum to “Zeaxanthin: Review of Toxicological Data and Acceptable Daily Intake” by James A. Edwards, Dirk Cremer

“…Subchronic OECD guideline studies with mice and rats receiving beadlet formulations of high-purity synthetic zeaxanthin in the diet at dosages up to 1000 mg/kg body weight (bw)/day, and in dogs at over 400 mg/kg bw/day, produced no adverse effects or histopathological changes. In developmental toxicity studies, there was no evidence of fetal toxicity or teratogenicity in rats or rabbits at dosages up to 1000 or 400 mg/kg bw/day, respectively. …”
Get full text

Effect of Uncaria rhynchophylla against Thioacetamide-Induced Acute Liver Injury in Rat by Mi-Rae Shin, Min Ju Kim, Jin A Lee, Seong-Soo Roh

“…In addition, the histopathological analysis showed that the liver tissue lesions were improved obviously by UR treatment. …”
Get full text

In situ immune response in human chromoblastomycosis--a possible role for regulatory and Th17 T cells. by Aline Alves de Lima Silva, Paulo Ricardo Criado, Ricardo Spina Nunes, Wellington Luiz Ferreira da Silva, Luciane Kanashiro-Galo, Maria Irma Seixas Duarte, Mirian N Sotto, Carla Pagliari

“…<h4>Methodology</h4>Twenty-three biopsies of verrucous form were obtained from patients with clinical, culture and histopathological diagnostic of chromoblastomycosis, without treatment. …”
Get full text