Qingxuan Jiangya Decoction Reverses Vascular Remodeling by Inducing Vascular Smooth Muscle Cell Proliferation in Spontaneously Hypertensive Rats by Jianfeng CHU, Fei XIAO, Meiling YANG, Yang FU, Feng ZHENG, Jun PENG

“…After eight weeks with the treatment of QXJYD, the aortas tissue was collected for histopathologic examination. The media thickness (MT) and lumen diameter (LD) were measured, ratio of lumen diameter/media thickness (LD/MT) in the carotid arteries were calculated, the gene and protein expression levels of Bax and Bcl-2 were detected.Results:SBP in SHR+QXJYD group was obviously lower than that in SHR group (<italic>P</italic>&lt;0.05). …”
Get full text

A Case of Hepatic Malignant Solitary Fibrous Tumor: A Case Report and Review of the Literature by Zhiyan Fu, Evita B. Henderson-Jackson, Barbara A. Centeno, Gregory Y. Lauwers, Mihaela Druta, Daniel A. Anaya, Yukihiro Nakanishi

“…The surgical specimen showed a well-circumscribe solid mass (14.6×13.0×10.0 cm) with necrosis. Histopathological examination revealed a proliferation of spindle tumor cells with characteristic staghorn-shaped blood vessels, frequent mitoses, and necrosis. …”
Get full text

Helicobacter pylori Pathogenicity Factors Related to Gastric Cancer by Kianoosh Dadashzadeh, Maikel P. Peppelenbosch, Akyala Ishaku Adamu

“…The prevalence of genotype was assessed by PCR and related to clinical histopathological parameters. Results. The relation of babA2 and babB negative and iceA1 positive genotype as a single genotype and the development of cases to GC was statistically significant (P<0.001). …”
Get full text

Pediatric pneumonia – A clinico-pathological study by Pragati A. Sathe, Monalisa Dash, Pradeep Vaideeswar, Sunil Karande, Lamk Kadiyani

“…Aims: This study was planned to describe the pulmonary histopathological patterns in cases of pediatric pneumonia (age <12 years) at autopsy and aimed to identify the probable etiology and correlate with clinical presentations. …”
Get full text

Comparison of Hepatoprotective Activity of Dhatri Lauha (DL) and Dhatri Lauha without Lauha Bhasma (DLWLB) on Carbon Tetrachloride Induced Hepatotoxicity in Wister Rats by Alka Gyanendra Yadav, Piyush Krantikumar Gandhi, Chatragun Eknathrao Lagad, Rajesh Kundlikrao Ingole, Sudhir Raghuttamrao Rajurkar

“…Hepatoprotective effects were analyzed using biochemical parameters such as serum alanine transaminase, serum aspartate transaminase, serum alkaline phosphatase, serum bilirubin, and histopathological studies of the liver.Results:Silymarin and the test drug-treated group showed an increased value of biochemical parameters on the 14th day, and significant decreases were observed on day 28th. …”
Get full text

Malignant Glandular Triton Tumor Arising in the Radial Nerve with Prolonged Survival: A Case Report and Review of the Literature by Batool M. AlAli, Samir S. Amr

“…Six months later, the patient was referred to our hospital, a tertiary care medical center, with recurrent swelling at the same location. Histopathological material from the referral hospital was reviewed, and the tumor was diagnosed as MPNST with rhabdomyoblastic differentiation or malignant triton tumor (MTT) that contained in addition foci of malignant glandular epithelium. …”
Get full text

F-2-Deoxy-2-Fluoro-D-Glucose Positron Emission Tomography, Computed Tomography, and Magnetic Resonance Imaging for the Detection of Experimental Colorectal Liver Metastases by Gabie M. de Jong, Thijs Hendriks, Robert P. Bleichrodt, Helena M. Dekker, Roel D.M. Mus, Martin Gotthardt, Eric P. Visser, Wim J.G. Oyen, Otto C. Boerman

“…Topographically, the liver was divided into eight segments and the image findings were compared on a segment-by-segment basis with the histopathologic findings. Sixty-four liver segments were analyzed, 20 of which contained tumor deposits. …”
Get full text

Effect of multiple-dose administration of carprofen on hematological and biochemical parameters in sheep by Duygu Durna Çorum, Ramazan Yıldız

“…However, safety needs to confirm by histopathological and molecular studies.…”
Get full text

Bleeding risk and prediction model to predict bleeding risk of tissue biopsy for definitive diagnosis in patients with suspected amyloidosis by Watsamon Uraiwan, Pirun Saelue

“…After obtaining histopathological reports, we randomly selected patients with and without amyloidosis at a ratio of 4:1.Results A total of 360 patients were enrolled before tissue biopsy. …”
Get full text

Metastatic Lesion of the Tibia from Renal Cell Carcinoma by Piotr Młodożeniec, Krzysztof Balawender, Mateusz Zasadny

“…The patient was treated with a laparoscopic radical nephrectomy with histopathologic confirmation of clear cell renal cell carcinoma. …”
Get full text

FGF21 and APOA1 mRNA-based therapies for the treatment of experimental acute pancreatitis by Amaya Lopez-Pascual, Eva Santamaria, Nuria Ardaiz, Iker Uriarte, Tiffany Palmer, Anne-Renee Graham, Celia Gomar, Roberto C. Barbero, M. Ujue Latasa, Maria Arechederra, Jesus M. Urman, Carmen Berasain, Antonio Fontanellas, Carlos L. del Rio, Maite G. Fernandez-Barrena, Paolo G.V. Martini, Joshua R. Schultz, Pedro Berraondo, Matias A. Avila

“…Serum levels of pancreatic lipase (LIPC), amylase (AMYL), and aspartate aminotransferase (AST), along with pancreatic tissue analyses using two histopathological scores were performed to evaluate treatment effects. …”
Get full text

The Beneficial Effect of Human Amnion Mesenchymal Cells in Inhibition of Inflammation and Induction of Neuronal Repair in EAE Mice by Jun Shu, Xiaojuan He, Hong Li, Xue Liu, Xuemei Qiu, Tongliang Zhou, Ping Wang, Xiaojie Huang

“…The results demonstrated that application of hAMC significantly ameliorated the disease severity and histopathological changes in EAE mice. The production of proinflammatory cytokines such as IFN-γ, TNF-α, IL-1β, and IL-17A in the spleen and CNS was dramatically inhibited. …”
Get full text

Adrenal Incidentalomas: Should We Operate on Small Tumors in the Era of Laparoscopy? by Michał Pędziwiatr, Michał Natkaniec, Mikhail Kisialeuski, Piotr Major, Maciej Matłok, Damian Kołodziej, Anna Zub-Pokrowiecka, Piotr Budzyński, Andrzej Budzyński

“…Operation parameters and histopathological results were analyzed. No differences in group characteristics, mean operation time, and estimated blood loss were noted. …”
Get full text

Nonfluent/Agrammatic PPA with In-Vivo Cortical Amyloidosis and Pick’s Disease Pathology by Francesca Caso, Benno Gesierich, Maya Henry, Manu Sidhu, Amanda LaMarre, Miranda Babiak, Bruce L. Miller, Gil D. Rabinovici, Eric J. Huang, Giuseppe Magnani, Massimo Filippi, Giancarlo Comi, William W. Seeley, Maria Luisa Gorno-Tempini

“…Three years later (11 years from first symptom), post-mortem histopathological evaluation revealed Pick's disease, with severe degeneration of left IFG, mid-insula, and precentral gyrus. …”
Get full text

Inhibition of Corneal Neovascularization by Topical and Subconjunctival Tigecycline by Sertan Goktas, Ender Erdogan, Rabia Sakarya, Yasar Sakarya, Mustafa Yılmaz, Muammer Ozcimen, Nejat Unlukal, Ismail Alpfidan, Fatih Tas, Erkan Erdogan, Abdulkadir Bukus, Ismail Senol Ivacık

“…Corneal sections were analyzed histopathologically. Results. The median percentages of corneal neovascularization in groups 1 and 3 were 48% (95% confidence interval (CI), 44.2–55.8%) and 33.5% (95% CI, 26.6–39.2%), respectively. …”
Get full text

PHARAOH: A collaborative crowdsourcing platform for phenotyping and regional analysis of histology by Kevin Faust, Min Li Chen, Parsa Babaei Zadeh, Dimitrios G. Oreopoulos, Alberto J. Leon, Ameesha Paliwal, Evelyn Rose Kamski-Hennekam, Marly Mikhail, Xianpi Duan, Xianzhao Duan, Mugeng Liu, Narges Ahangari, Raul Cotau, Vincent Francis Castillo, Nikfar Nikzad, Richard J. Sugden, Patrick Murphy, Safiyh S. Aljohani, Philippe Echelard, Susan J. Done, Kiran Jakate, Zaid Saeed Kamil, Yazeed Alwelaie, Mohammed J. Alyousef, Noor Said Alsafwani, Assem Saleh Alrumeh, Rola M. Saleeb, Maxime Richer, Lidiane Vieira Marins, George M. Yousef, Phedias Diamandis

“…Abstract Deep learning has proven capable of automating key aspects of histopathologic analysis. However, its context-specific nature and continued reliance on large expert-annotated training datasets hinders the development of a critical mass of applications to garner widespread adoption in clinical/research workflows. …”
Get full text

Giant Protruding Nodular Fasciitis of the Anterior Chest Wall Clinically Mimicking a Soft Tissue Sarcoma by Hideyuki Kinoshita, Tsukasa Yonemoto, Hiroto Kamoda, Yoko Hagiwara, Toshinori Tsukanishi, Sumihisa Orita, Kazuhide Inage, Naoya Hirosawa, Seiji Ohtori, Takeshi Ishii

“…Knowledge of the atypical clinical course and a combination of histopathological examinations are necessary to accurately diagnose NF.…”
Get full text

Evaluation of Six Patients with Pulmonary Carcinosarcoma with a Literature Review by Sinem Nedime Sökücü, Celalettin Kocatürk, Nur Ürer, Yaşar Sönmezoğlu, Levent Dalar, Levent Karasulu, Sedat Altın, Mehmet Ali Bedirhan

“…The preoperative diagnosis of carcinosarcoma of the lung is difficult due to the composition of the different histopathological structures. Complete surgical resection is the treatment of choice for pulmonary carcinosarcoma, although further studies are needed.…”
Get full text

First Account of Primary Leiomyosarcoma of the Lesser Omentum since Establishment of c-Kit Mutations in Gastrointestinal Stromal Tumors by Fumito Saijo, Kaoru Sato, Tomoko Handa, Yoichi Narushima, Naoki Matsumura, Noriyuki Iwama, Fumie Nakayama, Hiromi Tokumura

“…A laparoscopic partial resection of the stomach was performed. Histopathological examination revealed the tumor to be a leiomyosarcoma arising from the lesser omentum that did not invade the stomach. …”
Get full text

The Effects of Trimetazidine and Sildenafil on Bilateral Cavernosal Nerve Injury Induced Oxidative Damage and Cavernosal Fibrosis in Rats by Dogan Atilgan, Bekir S. Parlaktas, Nihat Uluocak, Fikret Erdemir, Fatma Markoc, Oguzhan Saylan, Unal Erkorkmaz

“…Tissue superoxide dismutase (SOD), malondialdehyde (MDA), and protein carbonyl (PC) levels were determined biochemically and distribution of cavernosal fibrosis density among groups was performed histopathologically. Results. Tissue SOD levels in BCI group were significantly lower than the control group (P<0.05). …”
Get full text