Can serum histone H4 levels predict mucosal healing in Crohn’s disease? by Ibrahim Hakki Köker, Bilge Sumbul Gultepe, Sercan Kiremitçi, Koray Koçhan, Ali Tuzun Ince, Elmas Biberci Keskin, Hakan Senturk

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Protocol for semisynthesis of histone H4 with site-specific modifications using irreversible sortase-mediated ligation by Yihang Xiao, Kun Zou, Mingxuan Wu

“…Summary: Post-translational modifications (PTMs) of histone H4 play significant roles in the regulation of chromatin status. …”
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By activating endothelium histone H4 mediates oleic acid-induced acute respiratory distress syndrome by Yanlin Zhang, Jingjin Tan, Yiran Zhao, Li Guan, Shuqiang Li

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Regulation of histone H4 acetylation in the CNS and defensive behavior command neurons of the mollusk Helix mediated by serotonin and neuropeptide FMRFamide by L. N. Grinkevich, T. G. Zachepilo

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p300/Sp1-Mediated High Expression of p16 Promotes Endothelial Progenitor Cell Senescence Leading to the Occurrence of Chronic Obstructive Pulmonary Disease by Zhihui He, Huaihuai Peng, Min Gao, Guibin Liang, Menghao Zeng, Xuefeng Zhang

“…Conclusion. p300/Sp1 enhanced the histone H4 acetylation level in the p16 promoter region to mediate the senescence of EPCs.…”
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Peculiarities of the molecular composition of heterochromatin associated with pronucleoli in mouse embryos by I. O. Bogolyubova, Z. K. Sailau, D. S. Bogolyubov

“…Intriguingly, these zones contain not only tri-methylated histone Н3K9me3 as an epigenetic mark of repressed chromatin but also acetylated histone H4K5ac, a well-known marker of active chromatin. …”
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PRMT1 Promotes the Self‐renewal of Leukemia Stem Cells by Regulating Protein Synthesis by Min Zhou, Yi Huang, Ping Xu, Shuyi Li, Chen Duan, Xiaoying Lin, Shilai Bao, Waiyi Zou, Jingxuan Pan, Chang Liu, Yanli Jin

“…Mechanistical studies reveal that PRMT1 promotes transcriptional activation of ribosomal protein L29 (RPL29) via catalyzing asymmetric dimethylation of histone H4R3 (H4R3me2a) at its gene promoter region. …”
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Identification of SETD4 as an Onco‐Immunological Biomarker Encompassing the Tumor Microenvironment, Prognoses, and Therapeutic Responses in Various Human Cancers by Yuyun Zhong, Ruiqi Wang, Zijie Huang, Zhaoting Hu, Bin Peng, Bin Chen, Liyue Sun

“…ABSTRACT Background SET domain‐containing protein 4 (SETD4) is a histone methyltransferase that has been shown to modulate cell proliferation, differentiation, and inflammatory responses by regulating histone H4 trimethylation (H4K20me3). Previous reports have demonstrated its function in the quiescence of cancer stem cells as well as drug resistance in several cancers. …”
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