Newly Generated Cells in the Dentate Gyrus Differentially Respond to Brief Spatial Exploration and Forced Swim in Adult Female Balb/C Mice by Gerardo Bernabé Ramírez-Rodríguez, María del Ángel Ocaña-Fernández, Leonardo Ortiz-López

“…Neurogenesis in the hippocampus is influenced by several factors including external stimuli. …”
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Neuroimaging Findings of Psychosis in Alzheimer's Disease: A Systematic Review by Fardin Nabizadeh, Shadi Sheykhlou, Sara Mahmoodi, Elham Khalili, Rasa Zafari, Helia Hosseini

“…On the basis of the included studies, there are significant changes in the volume and perfusion levels of broad brain areas, including the hippocampus, amygdala, insula, cingulate, occipital, frontal, prefrontal, orbitofrontal, temporal, and parietal cortices in these patients. …”
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The effect of space flight on genes expression in brain by A. S. Tsybko, T. V. Ilchibaeva, N. K. Popova

“…Also, the system of neuronal apoptosis is activated under the influence of microgravity as evidenced by changes in the expression of antiapoptotic protein Bcl-XL in the hippocampus and hypothalamus. The long spaceflight produced dysregulation in the genetic control of genes encoding GDNF and CDNF neurotrophic factors. …”
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Increased N-Ethylmaleimide-Sensitive Factor Expression in Amygdala and Perirhinal Cortex during Habituation of Taste Neophobia by Beatriz Gómez-Chacón, Fernando Gámiz, Thomas C. Foster, Milagros Gallo

“…In the present experiments we investigate both the behavioral performance and the expression profile of NSF and GluR2 genes in several brain areas, including PRh, BLA, and hippocampus. Twenty-one naïve male Wistar rats were exposed to a saccharin solution (0.4%) during the first (novel), the second (Familiar I), and the sixth presentation (Familiar II). …”
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Potentiation of Antidepressant Effects of Agomelatine and Bupropion by Hesperidin in Mice by Jegan Sakthivel Nadar, Pravin Popatrao Kale, Pramod Kerunath Kadu, Kedar Prabhavalkar, Ruchita Dhangar

“…Dopamine and serotonin levels were analysed in hippocampus, cerebral cortex, and whole brain using HPLC with fluorescence detector. …”
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Young Coconut Juice Reduces Some Histopathological Changes Associated with Alzheimer’s Disease through the Modulation of Estrogen Receptors in Orchidectomized Rat Brains by Tatcha Balit, Mosaad A. Abdel-Wahhab, Nisaudah Radenahmad

“…The results showed that the number of NF200- and PV-reactive neurons in the hippocampus and cerebral cortex was significantly reduced in orx rats. …”
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Distinct disruptions in CA1 and CA3 place cell function in Alzheimer’s disease mice by Sanggeon Park, Mijeong Park, Eun Joo Kim, Jeansok J. Kim, Jeiwon Cho, Yeowool Huh

“…Summary: The hippocampus, a critical brain structure for spatial learning and memory, is susceptible to neurodegenerative disorders such as Alzheimer’s disease (AD). …”
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Hippocampal Regulation of Postsynaptic Density Homer1 by Associative Learning by Nicholas E. Clifton, Darren Cameron, Simon Trent, Lucy H. Sykes, Kerrie L. Thomas, Jeremy Hall

“…Here, we used in situ hybridization to quantify short and long Homer1 expression in the hippocampus following consolidation, retrieval, and extinction of associative fear memory, using contextual fear conditioning in rats. …”
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The Role of Silymarin in Mitigating Inflammation and Cognitive Impairment Induced by Ovariectomy in Wistar Rats by Razieh Moalefshahri, Hossein Javid, Fatemeh Gheybi, Somaye Fallahnezhad, Seyed Isaac Hashemy

“…It also significantly reduced IL-1β, TNF-α, and IL-6 levels in the cortex, hippocampus, and liver (P≤0.05 to P≤0.0001) and increased CAT and SOD while decreasing MDA levels (P≤0.05 to P≤0.001) compared to control and sham groups. …”
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Role of PPARs in Progression of Anxiety: Literature Analysis and Signaling Pathways Reconstruction by Olga I. Rudko, Artemii V. Tretiakov, Elena A. Naumova, Eugene A. Klimov

“…High concentrations of PPARs are found in parts of the brain linked to anxiety development, including hippocampus and amygdala. Among three PPAR isoforms, PPARG demonstrates the highest expression in CNS, where it can be found in neurons, astrocytes, and glial cells. …”
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Dissociative experiences alter resting state functional connectivity after childhood abuse by Claudius von Schröder, Richard O. Nkrumah, Traute Demirakca, Gabriele Ende, Christian Schmahl

“…A DES by CTQ-A (childhood abuse) interaction predicted an anti-correlation between the raMFG and right hippocampus, moderated by CTQ-A. The CTQ revealed negative connectivity between the raMFG and right anterior cingulate cortex. …”
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Transient cortical beta-frequency oscillations associated with contextual novelty in high density mouse EEG by Callum Walsh, Luke Tait, Maria Garcia Garrido, Jonathan T. Brown, Thomas Ridler

“…Discrete epochs of beta (or Beta2) oscillations are prevalent in the hippocampus and other brain areas during exploration of novel environments. …”
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Hippocampal Proliferation Is Increased in Presymptomatic Parkinson’s Disease and due to Microglia by Karlijn J. Doorn, Benjamin Drukarch, Anne-Marie van Dam, Paul J. Lucassen

“…Besides dopamine-deficiency related motor symptoms, nonmotor symptoms, including cognitive changes occur in Parkinson's disease (PD) patients, that may relate to accumulation of α-synuclein in the hippocampus (HC). This brain region also contains stem cells that can proliferate. …”
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Reduced Expression of Voltage-Gated Sodium Channel Beta 2 Restores Neuronal Injury and Improves Cognitive Dysfunction Induced by Aβ1-42 by Shan Li, Guo-Ji Yan, Ya-Xin Tan, Lu-Lu Xue, Ting-Hua Wang, Hao-Ran Zhao, Min-Nan Lu, Hui-Xiang Zhang, Rong Mei, Xiao-Han Dong, Li-Na Liu, Dan Wang, Yan-Bin Xiyang

“…Voltage-gated sodium channel beta 2 (Nav2.2 or Navβ2, coded by SCN2B mRNA), a gene involved in maintaining normal physiological functions of the prefrontal cortex and hippocampus, might be associated with prefrontal cortex aging and memory decline. …”
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Modulation of Adult Hippocampal Neurogenesis by Early-Life Environmental Challenges Triggering Immune Activation by Ksenia Musaelyan, Martin Egeland, Cathy Fernandes, Carmine M. Pariante, Patricia A. Zunszain, Sandrine Thuret

“…A growing number of studies have shown that pre- and postnatal exposure to an inflammatory stimulus can modulate the number of proliferating and differentiating neural progenitors in the adult hippocampus, and this can have an effect on behaviours of relevance to psychiatric disorders. …”
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Sports participation & childhood neurocognitive development by Fu-Miao Tan, Junhong Yu, Alicia M. Goodwill

“…However, participation in any sport at baseline was associated with superior performance in various cognitive domains (i.e. inhibition, processing speed, and others), greater subcortical GM volume (i.e. cerebellum cortex, amygdala, hippocampus, and others), and whole-brain WM integrity compared to non-participants. …”
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Transcriptomic analysis reinforces the implication of spatacsin in neuroinflammation and neurodevelopment by Liriopé Toupenet Marchesi, Daniel Stockholm, Typhaine Esteves, Marion Leblanc, Nicolas Auger, Julien Branchu, Khalid Hamid El Hachimi, Giovanni Stevanin

“…To elucidate its function, we conducted an extensive RNA sequencing (RNAseq) experiment and transcriptomic analysis in three distinct neural structures (cerebellum, cortex and hippocampus) and at three different ages (6 weeks, 4 months and 8 months) in both wild type and Spg11 −/− mice. …”
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Three-Dimensional Organoid System Transplantation Technologies in Future Treatment of Central Nervous System Diseases by NaiLi Wei, ZiFang Quan, Hailiang Tang, JianHong Zhu

“…In recent years, scientists have made great achievements in understanding the development of human brain and elucidating critical elements of stepwise spatiotemporal control strategies in neural stem cell specification lineage, which facilitates successful induction of neural organoid in vitro including the cerebral cortex, cerebellar, neural tube, hippocampus cortex, pituitary, and optic cup. Besides, emerging researches on neural organogenesis promote the application of 3D organoid system transplantation in treating central nervous system (CNS) diseases. …”
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Electrophysiology-based screening identifies neuronal HtrA serine peptidase 2 (HTRA2) as a synaptic plasticity regulator participating in tauopathy by Naizhen Zheng, Kun Li, Jing Cao, Zijie Wang, Liang Zhang, Zihao Zhao, Jiawei He, Yong Wang, Xiang Zhu, Yiqing Chen, Jian Meng, Dongdong Zhao, Mengxi Niu, Hong Luo, Xian Zhang, Hao Sun, Yun-wu Zhang

“…Furthermore, adeno-associated virus (AAV)-mediated HTRA2 downregulation in the hippocampus impaired synaptic plasticity and cognitive function in C57BL/6 mice. …”
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Altered Structural and Functional Connectivity of Juvenile Myoclonic Epilepsy: An fMRI Study by Chengqing Zhong, Rong Liu, Cheng Luo, Sisi Jiang, Li Dong, Rui Peng, Fuqiang Guo, Pu Wang

“…The decreased GMV regions were found in the bilateral anterior cerebellum, the right orbital superior frontal gyrus, the left middle temporal gyrus, the left putamen, the right hippocampus, the bilateral caudate, and the right thalamus. …”
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