Platelet signaling in immune landscape: comprehensive mechanism and clinical therapy by Mengyao Yan, Zhe Wang, Zhiwei Qiu, Yimin Cui, Qian Xiang

“…Abstract Platelets are essential for blood clotting and maintaining normal hemostasis. In pathological conditions, platelets are increasingly recognized as crucial regulatory factors in various immune-mediated inflammatory diseases. …”
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Recent Advances in Pathogenesis and Anticoagulation Treatment of Sepsis-Induced Coagulopathy by Man C, An Y, Wang GX, Mao EQ, Ma L

“…Recent studies suggest that endothelial cells play an important role in immunoregulation and hemostasis. Meanwhile, the non-anticoagulation effects of anticoagulants, especially heparin, which act in the pathogenesis of coagulopathy in septic patients, have been partially revealed. …”
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Vascular cytoprotection, autoimmune disease, and premature atherosclerosis by Justin C Mason

“…A healthy vascular endothelium is critical to health, and interference with endothelial homeostasis disrupts hemostasis, regulation of vascular tone and blood pressure, leukocyte trafficking, angiogenesis and tissue repair. …”
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Ligating the varicose vein trunk for bleeding stomal varices in portal hypertension: a case report by Jialiang Sun, Zhanhai Tan, Jifa Zhang

“…The patient was acquired with successful hemostasis through high ligation of the various vein primary trunk, and stripping of the vein balls around stoma, along with intracutaneously suturing of the sub-abdominal wall varicose veins. …”
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Adhesion of Neisseria meningitidis to dermal vessels leads to local vascular damage and purpura in a humanized mouse model. by Keira Melican, Paula Michea Veloso, Tiffany Martin, Patrick Bruneval, Guillaume Duménil

“…Importantly, infection also led to local vascular damage with hemostasis, thrombosis, vascular leakage and finally purpura in the grafted skin, replicating the clinical presentation for the first time in an animal model. …”
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Combined Use of Clips and Nylon Snare (“Tulip-Bundle”) as a Rescue Endoscopic Bleeding Control in a Mallory-Weiss Syndrome by Hrvoje Ivekovic, Bojana Radulovic, Suzana Jankovic, Pave Markos, Nadan Rustemovic

“…However, no strict recommendations exist in regard to the mode of action after a failure of primary endoscopic hemostasis. We report a case of an 83-year-old male with MWS and rebleeding after the initial endoscopic treatment with epinephrine and clips. …”
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Protease-activated receptors in vascular smooth muscle cells: a bridge between thrombo-inflammation and vascular remodelling by Anxhela Habibi, Wolfram Ruf, Leon Schurgers

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Overview of Platelet Physiology: Its Hemostatic and Nonhemostatic Role in Disease Pathogenesis by Kakali Ghoshal, Maitree Bhattacharyya

“…Platelets are small anucleate cell fragments that circulate in blood playing crucial role in managing vascular integrity and regulating hemostasis. Platelets are also involved in the fundamental biological process of chronic inflammation associated with disease pathology. …”
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Emerging Delivery Strategies of Platelet-Rich Plasma with Hydrogels for Wound Healing by Ya Zhang, Zi-Lin Wang, Ze-Peng Deng, Zi-Li Wang, Fei Song, Li-Li Zhu

“…Platelet-rich plasma (PRP), a platelet-rich plasma concentrate obtained from whole blood, has been widely used to treat wounds due to its high contents of growth factors that can not only play a role in the hemostasis, repair, and anti-infection of wounds but also promote cell proliferation, maturation, and angiogenesis. …”
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Resuscitation from a pH of 6.5: A Case Report and Review of Pathophysiology and Management of Extreme Acidosis from Hypovolemic Shock after Trauma by Alexander Balmaceda, Sona Arora, Ilan Sondheimer, McKenzie M. Hollon

“…We describe the effects of acute acidosis on the respiratory and cardiovascular systems and hemostasis. Finally, we discuss the pillars of management in patients with extreme acute acidosis due to hemorrhage: transfusion, treatment of hyperkalemia, and consideration of buffering acidosis with bicarbonate and hyperventilation.…”
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Antithrombotic activity of flavonoids and polyphenols rich plant species by Bojić Mirza, Maleš Željan, Antolić Andrea, Babić Ivana, Tomičić Maja

“…Prophylactic approaches include acetylsalicylic acid and clopidogrel therapy on the level of primary hemostasis, i.e., primary clot formation. In the last five years, in the USA, health care expenses related to cardiovascular diseases have increased 50 %, to over 350 billion dollars. …”
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Use of Vaginal Packing in the Management of Lower Uterine Segment Atony by Ihsan Bagli, Selami Erdem

“…CONCLUSION: Vaginal packing was found to be simple, safe, and feasible in terms of achieving hemostasis in cases of postpartum hemorrhage due to lower uterine segment atony. …”
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Impact of inflammation on recurrent gastroduodenal ulcer bleeding by Oksana N Sulaeva, P. G. Kondratenko, V. Yu. Dely, S. O. Zharikov

“…The 1st group included patients with sustained hemostasis, the 2nd - with recurrent bleeding within 3 days after admission to the hospital. …”
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Dengue infection changes the expressions of CD154 and CD148 in human platelets by Sayali Vedpathak, Sonali Palkar, AkhileshChandra Mishra, Vidya A Arankalle, Shubham Shrivastava

“…Platelets are essential for hemostasis and vascular integrity. Platelets recognize dengue virus through the DC-SIGN receptor. …”
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Severe Gingival Enlargement with Coexisting Erosive Lichen Planus in Severe Chronic Periodontitis Patient by Ambika Sharma, Chakshu Aggarwal, Vijay P. Mathur, Divesh Sardana

“…Electrocautery is an effective tool for the gingivectomy in severe inflammatory type of gingival enlargement because of rapid postoperative hemostasis. For the management of erosive lichen planus, long-term use of topical corticosteroids is an effective approach. …”
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Histopathological characterization of skin and muscle lesions induced by lionfish (Pterois volitans) venom in a murine experimental model by Cecilia Díaz, Arturo Chang-Castillo, Natalia Ortiz

“…Conclusion: This GAPR1-like protein and the hyaluronidase are probably responsible for the hemostasis impairment and hemorrhagic lesions observed in mouse skin, whereas muscle injuries can be indirectly caused by a combination of inflammatory and hemorrhagic events. …”
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Active Liver Bleed Caught During FAST Exam from Spontaneous Hemangioma Rupture: A Case Report by Raul Rodriguez, Nicole Aviles

“…Computed tomography subsequently confirmed an active subcapsular bleed of the liver, and patient was taken emergently to surgery for hemostasis from a ruptured liver hemangioma. This was then followed by a right hepatic arterial embolization. …”
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Current Concepts in the Biopsy of Musculoskeletal Tumors by Costantino Errani, Francesco Traina, Fabrizio Perna, Carlotta Calamelli, Cesare Faldini

“…Technical considerations include proper location and orientation of the biopsy incision and meticulous hemostasis. It is necessary to obtain tissue for a histological diagnosis without spreading the tumor and so compromise the treatment. …”
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Effect of Collagen/Ibuprofen Hydrogel in Wound Healing: An In Vivo Study by Kamyar Abbasi, Reza Eftekhar Ashtiani, Mitra Abdolahi, Maryam Hosseini, Reza Sayyad Soufdoost, Mostafa Alam, Sadaf Fani-Hanifeh

“…Wound healing is a complicated physiological process to preserve skin integrity after injuries and includes the proliferative phase, hemostasis/inflammatory phase, and remodeling through extracellular, intercellular, and intracellular components synchronization. …”
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The Largest Tubal Pregnancy: 14th Week by Amr Elmoheen, Waleed Salem, Mahmoud Eltawagny, Rehab Elmoheen, Khalid Bashir

“…The patient had a successful laparotomy with salpingectomy and hemostasis and did well after the operation. So, an intact ectopic tubal pregnancy may last until the 14th week of gestation.…”
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