Antitumor immunostimulatory effect via cell-killing action of a novel extracorporeal blood circulating photodynamic therapy system using 5-aminolevulinic acid by Hidetaka Maegawa, Masayuki Kohashi, Yasuo Harada, Akira Tanaka, Shimpei Kajiwara, Takashi Fujimoto, Hidehiro Atagi, Kenta Kaneda

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One Year Duration of Immune Response Following a 3rd Booster Dose of mRNA Vaccine Against COVID‐19 in 292 Patients With Hematological Malignancies in University Hospital Ostrava, Czech Republic by Ondrej Šušol, Barbora Šušolová, Ondřej Klempíř, Milan Navrátil, Jaromír Gumulec, Zdeněk Kořístek, Juraj Ďuraš, Michal Kaščák, Jana Mihályová, Lukáš Stejskal, Tomáš Jelínek, Petra Richterová, Lenka Szeligová, Hana Plonková, Jana Zuchnická, Barbora Dluhošová, Ivo Demel, David Buffa, Katarína Hradská, Tereza Popková, Ludmila Muroňová, Martin Lachnit, Klára Lančová, Roman Hájek

“…Materials and Methods We have vaccinated 292 patients with all hematological malignancies with a third dose of mRNA COMIRNATY vaccine with a 12‐month follow‐up period in our center in Ostrava, Czech Republic. …”
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Synthesis and Anti-Cancer Activity In Vitro of Synephrine Derivatives by Ekaterina M. Zhidkova, Evgeniya S. Oleynik, Ekaterina A. Mikhina, Daria V. Stepanycheva, Diana D. Grigoreva, Lyubov E. Grebenkina, Kirill V. Gordeev, Ekaterina D. Savina, Andrey V. Matveev, Marianna G. Yakubovskaya, Ekaterina A. Lesovaya

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Editorial: Two decades of targeted therapies in hematology: new targets and novel combinations by Bruno António Cardoso, Bruno António Cardoso, Natalia Neparidze

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CRISPR-Cas9 in basic and translational aspects of cancer therapy by Maryam Samareh Salavatipour, Zahra Poursalehi, Negin Hosseini Rouzbahani, Sohaib Mohammadyar, Mohammad Vasei

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Critically ill adult patients with acute leukemia: a systematic review and meta-analysis by Dara Chean, David Luque-Paz, Daniele Poole, Sofiane Fodil, Etienne Lengliné, Thibault Dupont, Achille Kouatchet, Michael Darmon, Élie Azoulay

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Pharmacological activity of OST-01, a natural product from baccharis coridifolia, on breast cancer cells by HyunJun Kang, Dinh Hoa Hoang, Melissa Valerio, Khyatiben Pathak, William Graff, Alexis LeVee, Jun Wu, Mark A. LaBarge, David Frankhouser, Russell C. Rockne, Patrick Pirrotte, Bin Zhang, Joanne Mortimer, Le Xuan Truong Nguyen, Guido Marcucci

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A Rare Case of Immunotactoid Glomerulopathy Associated with Hodgkin Lymphoma by Keiki Nagaharu, Yuka Sugimoto, Keiki Kawakami

“…In hematologic malignancies, multiple myeloma and other mature B-cell malignancies are the most common hematologic malignancies, and Hodgkin lymphoma (HL) is extremely rare. …”
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The Use of Natural Health Products Especially Papaya Leaf Extract and Dandelion Root Extract in Previously Untreated Chronic Myelomonocytic Leukemia by Leena T. Rahmat, Lloyd E. Damon

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Bacteremia due to Leuconostoc pseudomesenteroides in a Patient with Acute Lymphoblastic Leukemia: Case Report and Review of the Literature by Kazuko Ino, Kazunori Nakase, Kei Suzuki, Akiko Nakamura, Atsushi Fujieda, Naoyuki Katayama

“…Infections due to Leuconostoc species have been reported in various immunocompromised patients, but little is known about such infection in patients with hematologic malignancies. We report a case of Leuconostoc infection in a 44-year-old woman with acute lymphoblastic leukemia. …”
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The AST/ALT (De Ritis) ratio as a significant prognostic factor in myelodysplastic syndrome by Ying Chen, Yue Wu, Ting Chen, Duobing Zou, Cong Shi, Ningning Wu, Lixia Sheng, Guifang Ouyang, Qitian Mu

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Malignant Lymphoma Presenting as Fulminant Hepatic Failure by Elizabeth Nizalik, Ekrem Zayed, Annette Foyle

“…A review of the literature yields 11 other cases with hematologic malignancies with similar presentation. To the authors’ knowledge this is the first case in which cell marker analysis was performed. …”
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Lenalidomide-Associated ITP by Christina I. Herold, Cristina Gasparetto, Gowthami M. Arepally

“…Lenalidomide is a potent immunomodulatory agent being used increasingly for treatment of hematologic malignancies including multiple myeloma and myelodysplasia. …”
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T-Cell Traffic Jam in Hodgkin's Lymphoma: Pathogenetic and Therapeutic Implications by Claudio Fozza, Maurizio Longinotti

“…In hematologic malignancies, the microenvironment is often characterized by nonneoplastic cells with peculiar phenotypic and functional features. …”
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Spontaneous Tumor Lysis Syndrome due to Uterine Leiomyosarcoma with Lung Metastases by Vivek Alaigh, Debapriya Datta

“…TLS is usually seen after the initiation of chemotherapy for hematologic malignancies. TLS occurring spontaneously, without initiation of chemotherapy, is rare and its occurrence in solid tumors is rarer still. …”
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Left Kidney Undifferentiated Spindle Cell Sarcoma with Myeloid Cell Leukemia-1 Amplification: Therapeutic Response to Bortezomib, Venetoclax, and Dexamethasone Therapy by Cheng-Yu Tang, Chueh-Chuan Yen

“…The overexpression of myeloid cell leukemia-1 (MCL-1) has been identified in numerous hematologic malignancies and solid tumors. Currently, there are no selective MCL-1 inhibitors. …”
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Sarcoidosis and Its Splenic Wonder: A Rare Case of Isolated Splenic Sarcoidosis by Khushali Jhaveri, Abhay Vakil, Salim R. Surani

“…Among the many considerations are hematologic malignancies, primary splenic or metastatic tumors, infiltrative disorders, inflammatory disorders, and infections. …”
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CAR-T cell therapy: developments, challenges and expanded applications from cancer to autoimmunity by Yaojie Kong, Jingyao Li, Xueyao Zhao, Yanwei Wu, Liang Chen

“…Chimeric Antigen Receptor (CAR)-T cell therapy has rapidly emerged as a groundbreaking approach in cancer treatment, particularly for hematologic malignancies. However, the application of CAR-T cell therapy in solid tumors remains challenging. …”
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Outcomes of follicular lymphoma with leukemic phase in the modern era: results from a large multicenter study by Asaad Trabolsi, Sunwoo Han, Narendranath Epperla, Kaitlin Annunzio, Firas Baidoun, Muhamad Alhaj Moustafa, Dan Morgenstern-Kaplan, Peter Doukas, Frederique St-Pierre, Brittany McCall, Lindsey Fitzgerald, Jose Sandoval-Sus, Shivani Dalal, Isildinha M. Reis, Jennifer Rose Chapman-Fredricks, Seo-Hyun Kim, Cherry Au, Natalie B. Otto, Khaled Alhamad, Thomas Ollila, Reem Karmali, Geoffrey Shouse, Izidore S. Lossos, Juan Pablo Alderuccio

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Multinational cohort study of intracranial hemorrhage in patients with brain metastases receiving anticoagulation by Eva N. Hamulyák, Tzu-Fei Wang, Lisa Baumann Kreuziger, Varun Iyengar, Brian J. Carney, Ann Hoeben, Berna C. Özdemir, Rosana D. Cordova Serrano, Kristen M. Sanfilippo, Shira Rozenblatt, Ludo F.M. Beenen, Shlomit Yust-Katz, Erez Halperin, Ariela Arad, Aharon Lubetsky, Marc Carrier, Benjamin Massat, Harry R. Büller, Galia Spectre, Jeffrey I. Zwicker, Avi Leader, ABC Study Group

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