The role of vitamin K2 in cognitive impairment: linking vascular health to brain health by Stefanos Roumeliotis, Ioannis Kontogiorgos, Femke de Vries, Katarzyna Maresz, Jean-François Jeanne, Konstantinos Leivaditis, Leon J. Schurgers

“…This condition presents a major challenge for the elderly, adversely affecting quality of life, diminishing independence, and imposing substantial burdens on healthcare systems. Recent research indicates that vitamin K2 may be vital for preserving brain health and cognitive function. …”
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Addressing healthcare professionals’ fatigue for effective climate action engagement by Eddie Robinson, Dinesh Bhandari, Ross Donohue, Zerina Lokmic-Tomkins

“…Climate change is a significant threat to public health, exacerbating existing challenges in healthcare systems. The anticipated impacts encompassing increased global surface temperatures, rising sea levels, water and food insecurity, geopolitical instability and the heightened frequency, duration, and intensity of natural disasters coupled with the healthcare sector's contribution to carbon emissions, necessitate urgent action from healthcare professionals. …”
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Fragmented care in lupus: Patient experiences and insights by Armand Bam

“…Results: Three primary themes emerged: the necessity of cohesive healthcare teams, the centrality of client-centred care and the significant challenges posed by fragmented healthcare systems. Conclusion: The study highlights the need for integrated care models to enhance communication and coordination among healthcare providers. …”
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Definition of Guideline-Based Metrics to Evaluate AAL Ecosystem’s Usability by Carlos Romeiro, Pedro Araújo

“…The elderly population growth has posed several challenges which the current healthcare systems are incapable of handling. In the past few years, there has been a close collaboration between both the scientific and industry communities to provide feasible solutions capable of addressing the growing demands from people with special needs, namely, in terms of assistance and improvement of their overall life quality, which promoted to the development of the ambient assisted living (AAL). …”
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Orthoplastic surgery research: Three decades of growth and future directions by Alexander F. Dagi, Michael B. Amrami, Nikhil A. Gangoli, Dylan K. Kim, Jarrod T. Bogue

“…Key opportunities to strengthen the field include conducting prospective studies, expanding research beyond lower extremity trauma to areas such as upper extremity reconstruction, oncologic applications, and paediatric care, addressing healthcare access disparities, evaluating cost-effectiveness across different healthcare systems, and developing standardized guidelines beyond the UK.…”
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Potential Use and Limitation of Artificial Intelligence to Screen Diabetes Mellitus in Clinical Practice: A Literature Review by Aqsha Nur, Defin Yumnanisha, Sydney Tjandra, Adang Bachtiar, Dante Saksono Harbuwono

“…Without screening, DM and its complications will impose significant pressure on healthcare systems. Current clinical practices for screening and diagnosing DM primarily involve blood or laboratory-based testing which possess limitations on access and cost. …”
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Bringing lab to the field: Exploring innovations in point-of-care diagnostics for the rapid detection and management of tropical diseases in resource-limited settings by Abdullahi Tunde Aborode, Ridwan Olamilekan Adesola, Godfred Yawson Scott, Emele Arthur-Hayford, Oche Joseph Otorkpa, Somuah Daniel Kwaku, Emmanuel Ebuka Elebesunu, Eghaghe Osadebamwen Nibokun, Ibude Jane Aruorivwooghene, Adetolase A. Bakre, Oluwaseun Adeolu Ogundijo, Olamilekan Gabriel Banwo, Oluwatobiloba Ige, Ibrahim O. Adelakun, Isreal Ayobami Onifade, Segun E. Ogungbemi, Boluwatife T. Dosunmu, Oluwaseunayo Deborah Ayando, Nike Idowu, Grace A. Adegoye, Olusegun Oluwaseun Jimoh

“…Key to their success is the need for interdisciplinary collaboration, sustainable funding models, and strong regulatory frameworks to ensure their effective integration into healthcare systems. The review emphasizes how point-of-care diagnostics can play a crucial role in reducing the burden of tropical diseases and advancing health equity on a global scale.…”
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Expression and Regulation of Hypoxia-Inducible Factor Signalling in Acute Lung Inflammation by Nikolaos S. Lotsios, Chrysi Keskinidou, Sotirios P. Karagiannis, Kostas A. Papavassiliou, Athanasios G. Papavassiliou, Anastasia Kotanidou, Ioanna Dimopoulou, Stylianos E. Orfanos, Alice G. Vassiliou

“…The significant burden that critical illnesses place on global healthcare systems highlights the need for a deeper understanding of underlying mechanisms and the development of innovative treatment strategies. …”
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Nurses' experiences of home care: A qualitative study by Atefeh Shamsi, Ahmadreza Yazdannik, Nayereh Naseri

“…Background: Addressing the challenges of home care is crucial for transforming traditional care models into modern healthcare systems. Objectives: The current study aimed to explore nurses' experiences of home care challenges. …”
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Understanding barriers to influenza vaccination among parents is important to improve vaccine uptake among children by Stephanie A. Davey, James Elander, Amelia Woodward, Michael G. Head, Daniel Gaffiero

“…This is especially concerning given the concurrent circulation of COVID-19 and influenza during the winter months, which places additional strain on healthcare systems. Drawing on existing evidence, this commentary examines key factors influencing childhood vaccination rates and provides preliminary policy recommendations to address these challenges. …”
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Toward humanistic healthcare through dystopian visions: Sally Wiener Grotta’s “One Widow’s Healing” by Meeyoung Kang

“…Results This story presents a dystopian vision of future healthcare systems in the highly technologically advanced and hyper-connected societies of 2100 and advocates for a reorientation of medicine toward a holistic, culturally informed practice that prioritizes human well-being and empathy. …”
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The impact of workplace violence on healthcare workers during and after the COVID-19 outbreak by C. Mento, G. Pandolfo, G. Spatari, M.C. Silvestri, I. Formica, A. Bruno, G. Falgares, M.R.A. Muscatello, C. La Barbiera, A. De Carlo

“…WPV not only affects the personal well-being of healthcare professionals but also compromises patient care quality and the efficiency of healthcare systems. Effective strategies are urgently needed to address WPV, such as comprehensive training in de-escalation techniques, organizational policies, and enhanced safety protocols. …”
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Hydrogels empowered mesenchymal stem cells and the derived exosomes for regenerative medicine in age-related musculoskeletal diseases by Lixin Liu, Siwen Chen, Yantao Song, Longwei Cui, Yiman Chen, Jiangli Xia, Yibo Fan, Liqun Yang, Lina Yang

“…As the population ages, musculoskeletal diseases (MSK) have emerged as a significant burden for individuals, healthcare systems, and social care systems. Recently, regenerative medicine has exhibited vast potential in age-related MSK, with mesenchymal stromal cells (MSCs) and their derived exosomes (Exos) therapies showing distinct advantages. …”
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End of life and palliative care decisions in advanced head neck cancer by Shrikant B. Mali

“…The complexity of care for patients with advanced head and neck cancer is a significant issue, and current healthcare systems must focus on appropriate referral criteria, increased integration and coordination of care, and robust evaluation of specific care components. …”
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Global screening of health behaviors: Introducing Lev-screening (Lev-s)-development and psychometric evaluation. by Douglas Sjöwall, Felicia Stålhand, Greta Schettini, Petter Gustavsson, Tatja Hirvikoski

“…Poor health behaviors have been identified as a critical factor for the burden on healthcare systems and individual suffering. However, comprehensive assessment of health behaviors is time-consuming and often neglected. …”
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Exploring similarities and differences in anti-atherosclerotic potential bioactives among Dendrobium species by UPLC-Q-Exactive Orbitrap MS by Yu Zhang, Xi Chen, Oushan Tang, Keyun Cheng, Lijun Ge, Weibo Lu, Jing Zheng, Yeshun Wu, Si-wei Wang, Xi-xi Zeng, Jing Xue, Yiwei Cui, Liting Ji, Qing Shen

“…Abstract Atherosclerosis is a primary cause of cardiovascular disease, straining healthcare systems. Dendrobium officinale, a widely used food-medicine homology, has demonstrated anti-atherosclerotic (anti-AS) properties, with other species listed in pharmacopoeias exhibiting similar effects. …”
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The Mathematical Modeling Approach for the Wastewater Treatment Process in Saudi Arabia during COVID-19 Pandemic by Abdullah Ahmadini, Ahmed Msmali, Zico Mutum, Yashpal Singh Raghav

“…The novel coronavirus disease (COVID-19) pandemic has had devastating effects on healthcare systems and the global economy. Moreover, coronavirus has been found in human feces, sewage, and in wastewater treatment plants. …”
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A Case Study on the Impact of an Adapted Community Jury in Shaping the Nutrition Standards for Hospital Menus in New South Wales Australia by Tara Dimopoulos-Bick, Melanie Schier, Kim Crawley, Kim Sutherland

“…It offers practical suggestions on adapting a community jury approach to strengthen patient, family, and community engagement across healthcare systems.…”
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Impact of machine learning on dietary and exercise behaviors in type 2 diabetes self-management: a systematic literature review by Rizwan Riaz Mir, Nazeef Ul Haq, Kashif Ishaq, Nurhizam Safie, Abdul Basit Dogar

“…Self-awareness and self-management in diabetes are critical as they enhance patient well-being, decrease financial burden, and alleviate strain on healthcare systems by mitigating complications and promoting healthier life expectancy. …”
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Experiences of Patients and Families Living with Krabbe Disease by Yuta Koto PhD, Wakana Yamashita MSN, Kumiko Kitamura MSN, Norio Sakai PhD

“…The categories were integrated into three themes: the impact of symptoms on daily life, challenges for healthcare systems, and challenges faced by family members. …”
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