Cost-benefit analysis of VKA versus NOAC treatment in German patients with atrial fibrillation utilizing patient self-testing by Roland Diel, Niklas Lampenius

“…**Background:** Clinical complications of long-term anticoagulation in patients with atrial fibrillation cause significant morbidity and have a substantial economic impact on the healthcare system. **Objective:** To assess the cost-benefit by implementing patient self-testing (PST) in German patients anticoagulated with vitamin K antagonists (VKA) compared to treatment with the new oral anticoagulant drugs (NOAC) apixaban, dabigatran, edoxaban, and rivaroxaban. …”
Get full text

The Effect of Community Based Intervention on People with Type 2 Diabetes Mellitus: Systematic Review by M Agung Akbar, Junaiti Sahar, Etty Rekawati, Ratu Ayu Dewi Sartika, Prateek Gupta

“…Integrating and strengthening health and community-based collaborations within the broader healthcare system is crucial for achieving optimal health outcomes. …”
Get full text

Development of a Japanese version of the patient perceptions of deprescribing – Short form by Mio Kushibuchi, Kenya Ie, Masaki Takahashi, Amy M. Linsky, Steven M. Albert

Get full text

Adherence to Dihydroartemisinin-Piperaquine Treatment among Patients with Uncomplicated Malaria in Northern Ghana by Abraham Rexford Oduro, Samuel Chatio, Paula Beeri, Thomas Anyorigiya, Rita Baiden, Philip Adongo, Patricia Akweongo

“…The determinants of such treatment adherence include patient, the health condition, therapy type, socioeconomic conditions, and the healthcare system. The study examined adherence in malaria patients treated with dihydroartemisinin-piperaquine in routine clinical care in northern Ghana. …”
Get full text

Prediabetes: Challenges, Novel Solutions, and Future Directions by Monique E Francois, Katie M Oetsch

“…T2D alone is predicted to cost the healthcare system upwards of 490 billion USD by 2030, thus addressing this growing burden is vital. …”
Get full text

Cardiovascular wellness in low-resource settings: A mobile app-based risk prediction study among fuel filling station employees in Puducherry district by Divyabharathy Ramadass, Jyothi Vasudevan, Madonna J. Dsouza, Baalaji Subramanian

“…The burden of NCDs puts a strain on the healthcare system, requiring an increased focus on preventive measures, early detection, and management of chronic conditions. …”
Get full text

A machine learning-based clinical predictive tool to identify patients at high risk of medication errors by Ammar Abdo, Lyse Gallay, Thibault Vallecillo, Justine Clarenne, Pauline Quillet, Vincent Vuiblet, Rudy Merieux

“…Abstract A medication error is an inadvertent failure in the drug therapy process that can cause serious harm to patients by increasing morbidity and mortality and are associated with significant economic costs to the healthcare system. Medication reconciliation is the most cost-effective intervention and can result in a 66% reduction in medication errors. …”
Get full text

Let us be heard: critical analysis and debate of collaborative research approaches used in implementation science research with equity-deserving populations by Sarah Madeline Gallant, Cynthia Mann, Britney Benoit, Megan Aston, Janet Curran, Christine Cassidy

“…The current opioid epidemic challenges healthcare systems to improve existing practices through implementation of evidence-based interventions. …”
Get full text

Lifetime Attributable Risk in Mammography Screenings in Dubai: The Influence of Breast Thickness and Age on Radiation Exposure by Kaltham Abdulwahid Mohd Noor, Norhashimah Mohd Norsuddin, Iza Nurzawani Che Isa, Muhammad Khalis Abdul Karim

“…<b>Methods:</b> A retrospective analysis was conducted on 2601 patients aged 40 to 69 across five screening facilities in Dubai’s healthcare system. Due to a low correlation between the mean glandular dose (MGD) and breast thickness, both glandular and non-glandular doses were included in calculations as the organ dose (OD). …”
Get full text

Burden of scrub typhus among patients with acute febrile illness attending tertiary care hospital in Chitwan, Nepal by Sangita Thapa, Pradip Hamal, Navin Kumar Chaudhary, Lokendra Bahadur Sapkota, Jaya Prasad Singh

“…There is utmost need of reliable diagnostic facilities at all levels of healthcare system in Nepal. Infection with scrub typhus was found high and this calls for an urgent need to introduce vaccine against scrub typhus. …”
Get full text

The safety and efficacy of neutral electrolyzed water solution for wound irrigation: post-market clinical follow-up study by Veronika Valdová, Vladimíra Štěpánová, Lenka Lapčíková

“…IntroductionChronic wounds are a significant public health challenge, representing a considerable burden on the healthcare system. There are numerous gaps in knowledge in the treatment of chronic wounds. …”
Get full text

Multiclass Supervised Learning Approach for SAR-COV2 Severity and Scope Prediction: SC2SSP Framework by Shaik Khasim Saheb, B. Narayanan, T.V. Narayana Rao

“…Accurate treatment requires an urgent need for early diagnosis, which reduces pressure on the healthcare system. Computed Tomography (CT) scan and Chest X-Ray (CXR) are some of the standard image diagnoses. …”
Get full text

Unmet needs in the management of migraine in Greece from the perspective of medical experts: a Delphi consensus by Georgia Kourlaba, Michail Vikelis, Theodoros Karapanayiotides, Argyro Solakidi, Dimitrios Trafalis, Katerina Lioliou, Panagiotis Andriopoulos, Aspasia Panagiotou, Dimos-Dimitrios Mitsikostas

“…Addressing these challenges could result in improvement of patient outcomes and reduction of the socioeconomic burden migraine imposes on individuals, healthcare system and the society.ObjectiveThis survey aimed to capture in Greece the perspective of medical experts (neurologists) specializing in migraine management regarding the socioeconomic burden of migraine and the unmet needs in diagnosis and treatment.MethodsAn online Delphi-based survey was conducted with 13 neurologists, experts in migraine. …”
Get full text

Acceptability and feasibility of pre-exposure prophylaxis for bacterial STIs: a systematic review. by Julie-Anne Carroll, Amy B Mullens, Sarah Warzywoda, Philip R A Baker, Meika Stafford, Faye McMillan, Jacintha Manton, Daniel Demant

“…<h4>Background</h4>A recent resurgence of bacterial sexually transmitted infections (STIs) is placing a major burden on high-risk populations, physicians, and the healthcare system. Treatment in the form of antibiotic pre-exposure prophylaxis (STI PrEP) is a potential solution. …”
Get full text

Adding capivasertib to fulvestrant in patients with hormone receptor-positive advanced breast cancer: a cost-effectiveness analysis by Yitian Lang, Qingqing Chai, Yan Lin, Bin Wu, Xiaoyan Liu

“…PSA demonstrated that capivasertib plus fulvestrant exhibited a 0% probability of cost-effectiveness in the US.ConclusionOur finding suggests that, at its current price, capivasertib plus fulvestrant regimen is unlikely to be a cost-effective option compared to fulvestrant alone for HR-positive advanced breast cancer patients from the perspective of healthcare system in the US. For the experimental analysis based on specific assumptions from Chinese perspective, the therapy regimen was also found to lack cost-effectiveness.…”
Get full text

Unpacking complex interventions that manage care for high-need, high-cost patients: a realist review by Eva Chang, Rania Ali, Nancy D Berkman

“…Identifying HNHC patients for an intervention can be best achieved through a multipronged strategy that accounts for their clinical and psychosocial complexity and prior experiences with the healthcare system. Successful interventions recognise that relationships with HNHC patients require the sustained engagement of care providers. …”
Get full text

Healthcare Resource Utilization and Cost Comparisons of High-Protein Enteral Nutrition Formulas Used in Critically Ill Patients by Matthew C. Bozeman, Laura L. Schott, Amarsinh M. Desai, Mary K. Miranowski, Dorothy L. Baumer, Cynthia C. Lowen, Zhun Cao, Krysmaru Araujo Torres

“…**Conclusions:** Using a select immunonutrition formula for critically ill patients may provide overall cost savings for the healthcare system.…”
Get full text

Multi-functional dressings for recovery and screenable treatment of wounds: A review by F. Moradifar, N. Sepahdoost, P. Tavakoli, A. Mirzapoor

“…The increasing emphasis on health and medical treatment is crucial to the modern healthcare system. Consequently, high-quality wound dressings with advanced standards are essential for superior medical care. …”
Get full text

Unhealthy alcohol use and risk of coronary heart disease among young and middle-aged adults by Jamal S. Rana, Felicia W. Chi, Isaac Acquah, Stacy A. Sterling

“…Methods: An observational study in an integrated healthcare system with systematic alcohol screening. We identified 432,265 primary care patients aged 18–65 years who, in 2014–2015, reported weekly alcohol intake levels. …”
Get full text

Comprehensive evaluation of compound Kushen injection combined with zoledronic acid in treating bone metastasis cancer pain based on meta-analysis and decision tree model by Xi Zhao, Tianwei Meng, Kaiqiang Wang, Xi Yan, Yuqiang Liu, Xinghua Li

“…A cost-effectiveness analysis from the perspective of China's healthcare system employed a decision tree model to evaluate the short-term economic impact of the two treatment regimens. …”
Get full text