Resveratrol, a food-derived polyphenol, promotes Melanosomal degradation in skin fibroblasts through coordinated activation of autophagy, lysosomal, and antioxidant pathways by Saki Okamoto, Saya Kakimaru, Mayuko Koreishi, Mika Sakamoto, Yoshimasa Nakamura, Hideya Ando, Yoshio Tsujino, Ayano Satoh

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A data pipeline for secure extraction and sharing of social determinants of health. by Tyler Schappe, Lisa M McElroy, Moronke Ogundolie, Roland Matsouaka, Ursula Rogers, Nrupen A Bhavsar

“…However, sharing of these data across health systems presents challenges. We set out to develop a pipeline to acquire, deidentify, and share neighborhood-level SDOH data across multiple health systems.…”
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What are the barriers to the diagnosis and management of chronic respiratory disease in sub-Saharan Africa? A qualitative study with healthcare workers, national and regional polic... by Angela Obasi, Rachel Tolhurst, Kingsley Rex Chikaphupha, Miriam Taegtmeyer, Kevin Mortimer, Louis Niessen, Maia Lesosky, Jahangir Khan, William Worodria, Jamie Rylance, Lindsay Zurba, Imelda Bates, Stellah G Mpagama, Elizabeth Henry Shayo, Rose Oronje, Emmanuel Addo-Yobo, Brian Allwood, Hastings Banda, Amsalu Binegdie, Adegoke Falade, Bertrand Mbatchou, Beatrice Mutayoba, Nyanda Elias Ntinginya, Heather Zar, Eliya Zulu, Helen Meme, Uzochukwu Egere, Asma Elsony, Martha Chinouya, S Bertel Squire, Stephen Mulupi, Irene Ayakaka, Nicole Kozak, Elhafiz Abdalla, Rashid Osman

“…Appropriate diagnosis and management require health systems strengthening, particularly at the primary healthcare level.…”
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Multidrug-resistant ESBL E. coli in urban surface waters and public health implications: A Case Study from Goranchatbari, Dhaka by Md. Sakib Hossain, Ahmed Ishtiaque Amin Chowdhury, Mohammad Rafiqul Islam, Ripan Kirtunia, Md. Foysal Abedin, Mohammad Atique Ul Alam, Shampa, Sonia Binte Murshed, Md Shadman Sakib, Siam Alam, M. Shahjahan Mondal, Zahid Hayat Mahmud

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Nebulized dexmedetomidine in the treatment of obstetric post-dural puncture headache: two case reports by Jeffrey Thomas, Leonard J. Soloniuk, Chris Mehdizadeh, Peter Cheng, Ashish Sinha

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Serious Intestinal Diseases Parasitism. A case presentation. by Rubén Bembibre Taboada, Magalys Olivert Cruz, Pedro Juan Barrios Fuentes

“…In countries with developed health systems as ours, the report of parasitic diseases with torpid evolution is very rare. …”
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Digital health interventions for improving access to primary care in India: A scoping review. by Lenny Vasanthan, Sindhu Kulandaipalayam Natarajan, Andrew Babu, Mohan S Kamath, Sureshkumar Kamalakannan

“…The use of digital technologies can not only strengthen health systems but also improve access to health care, particularly for the vulnerable. …”
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Determinants of the Continuum of Maternal Healthcare Services in Northwest Ethiopia: Findings from the Primary Health Care Project by Asmamaw Atnafu, Adane Kebede, Bisrat Misganaw, Destaw Fetene Teshome, Gashaw Andargie Biks, Getu Debalkie Demissie, Haileab Fekadu Wolde, Kassahun Alemu Gelaye, Mezgebu Yitayal, Tadesse Awoke Ayele, Telake Azale, Terefe Derso, Tsegaye Gebremedhin, Endalkachew Dellie

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Community Malaria Knowledge, Experiences, Perceived Roles, and Acceptability of Community-Directed Distribution of Intermittent Preventive Therapy for Pregnancy in Rural Southeast... by Ijeoma Nkem Okedo-Alex, Ifeyinwa Chizoba Akamike, Johnbosco Ifunanya Nwafor, Chihurumnanya Alo, Adaoha Pearl Agu, Dejene Derseh Abateneh, Chigozie Jesse Uneke

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Cold temperature-related attributable risk for emergency circulatory hospitalizations, length of stay, and healthcare costs in Hong Kong by Eliza Lai-Yi Wong, Hong Qiu

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Three in four children age 12–23 months missed opportunities for vaccination in Sub-Saharan African countries: a multilevel mixed effect analysis of demographic health and surveys... by Melak Jejaw, Tesfahun Zemene Tafere, Misganaw Guadie Tiruneh, Asebe Hagos, Getachew Teshale, Mikias Mered Tilahun, Wubshet D. Negash, Kaleb Assegid Demissie

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Chronic Noncommunicable Diseases: a Current Look at the Challenge by Miguel Ángel Serra Valdés

“…Chronic noncommunicable diseases are currently one of the major challenges facing health systems worldwide given the large number of people affected, their increasing incidence, their gradual contribution to overall mortality, the disability caused by them, and the high cost of hospitalization, medical treatment, and subsequent rehabilitation. …”
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COVID-19 preparedness and response in rural and remote areas: A scoping review. by Lilian Dudley, Ian Couper, Niluka Wijekoon Kannangarage, Selvan Naidoo, Clara Rodriguez Ribas, Theadora Swift Koller, Taryn Young

“…Equity-oriented rural health systems strengthening and action on rural social determinants is essential to better prepare for and respond to future outbreaks.…”
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Health and tuberculosis systems resilience, the role of the private sector and pandemic preparedness: insights from a cross-country qualitative study with policy-makers in India, I... by Madhukar Pai, Poshan Thapa, Charity Oga-Omenka, Angelina Sassi, Vijayashree Yellappa, Petra Heitkamp, Bony Wiem Lestari, Surbhi Sheokand, Nathaly Aguilera Vasquez, Laura Jane Brubacher, Bolanle Olusola-Faleye, Joel Shyam Klinton

“…Introduction The COVID-19 pandemic was an unprecedented challenge to health systems worldwide and had a severe impact on tuberculosis (TB) case notifications and service delivery. …”
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How the Content of Interprofessional Safety Management Education Can Be Structured Through the Perception of Nursing Home Practitioners: A Mixed Methods Design by You Jung Hong, Dayeong Kim, Sung Ok Chang

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Insights into prostate cancer awareness and perceptions among men in Tshwane by L Nzombe, J Shirinde, S Patrick

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Experience of Initial Symptoms of Breast Cancer and Triggers for Action in Ethiopia by Timothy D. Dye, Solomon Bogale, Claire Hobden, Yared Tilahun, Teshome Deressa, Anne Reeler

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An investigation of factors associated with antenatal care attendance in Gauteng in 2015 by E M Webb, B Girdler-Brown, J Mostert, S Ngcobo

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Digital interventions for adolescents with type 1 diabetes to promote health literacy? A qualitative study on physicians’ perspective in Germany by Hürrem Tezcan-Güntekin, Aurélia Naoko Naef, Nadine Fischbock, Volker Eric Amelung

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