Tumor mutational burden quantification from targeted gene panels: major advancements and challenges by Sara Gandini, Laura Fancello, Pier Giuseppe Pelicci, Luca Mazzarella

“…Moreover, we highlight how various experimental, platform-related or methodological variables, as well as bioinformatic pipelines, influence panel-based TMB quantification. The lack of harmonization in panel-based TMB quantification, of adequate methods to convert TMB estimates across different panels and of robust predictive cutoffs, currently represents one of the main limitations to adopt TMB as a biomarker in clinical practice. …”
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Research on low carbon dispatch technology for wind and solar grid connection in the Gobi Desert and barren land areas by Yanhong Ma, QingQuan Lv, Jianmei Zhang, Chunxiang Yang, Qiang Zhou

“…Concurrently, the lower-level model harmonizes various peak-shaving resources and incorporates a tiered carbon trading cost, thus establishing a multi-objective “source-grid-load-storage” collaborative low-carbon scheduling framework. …”
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Convenient estimation of oxytetracycline and polymyxin B by a novel high-performance liquid chromatography method: development and validation by Tanu Chaudhary, Balak Das Kurmi, Dilpreet Singh

“…Accuracy showed acceptable recovery of prepared concentrations as per International Conference on Harmonization (ICH) guidelines. Moreover, the developed method was found to be robust and rugged, as per specified ranges. …”
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Community-engaged artificial intelligence research: A scoping review. by Tyler J Loftus, Jeremy A Balch, Kenneth L Abbott, Die Hu, Matthew M Ruppert, Benjamin Shickel, Tezcan Ozrazgat-Baslanti, Philip A Efron, Patrick J Tighe, William R Hogan, Parisa Rashidi, Michelle I Cardel, Gilbert R Upchurch, Azra Bihorac

“…Only one article described inclusion of community stakeholders in designing an application-a natural language processing model that detected cases of likely child abuse with 90% accuracy using harmonized electronic health record notes from both hospital and community practice settings. …”
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Piezoresistive Cantilever Microprobe with Integrated Actuator for Contact Resonance Imaging by Tianran Ma, Michael Fahrbach, Erwin Peiner

“…Meanwhile, fitting of the measured contact-resonance spectra was applied based on a Fano-type line shape to reveal the material-specific signature of a single harmonic resonator. However, noise is greatly increased with the bending mode and contact force increasing on viscoelastic samples. …”
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On the obligations of states to respond to climate change and China’s legal consequences: based on the advisory opinion in case no. 31 of the international tribunal for the law of... by Wanping Zeng, Wanping Zeng, Guihua Wang, Guihua Wang

“…The analysis identifies key challenges, including expanded legal responsibilities, the harmonization of international law with domestic legislation, and the increased risk of international climate litigation for domestic enterprises.ResultsThe Advisory Opinion establishes a higher standard for China’s legislative response to climate change, necessitating the integration of its international obligations into its domestic legal framework. …”
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Power flow and power quality improvement of a residential-industrial microgrid using 72-pulse inverter-based UIPC by Mahyar Abasi, Ali Nahavandi, Javad Ebrahimi, Gevork B. Gharehpetian

“…This article offers a design of simultaneous reactive-active power control, total harmonic distortion reduction, and voltage unbalance compensation at the connection point of an industrial-residential microgrid, containing an electric arc furnace and a wind farm, to a power system. …”
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British Policy and Strategy in the Middle East in 1941: Three Wars ‘East of Suez’ by A. M. Fomin

“…In the Iran’s case, the necessity of harmonizing policies with the Soviet Union came to the fore. …”
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Exploration of the optimal deep learning model for english-Japanese machine translation of medical device adverse event terminology by Ayako Yagahara, Masahito Uesugi, Hideto Yokoi

“…Mapping between the JFMDA terminology collection and the IMDRF-AET is critical to international harmonization. However, the process of translating the terminology collections from English to Japanese and reconciling them is done manually, resulting in high human workloads and potential inaccuracies. …”
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Plant breeders' rights by Lončar Gordana

“…By acceding to this Convention, Serbia decided to respect its principles, and accordingly adopted a harmonized Law on the Protection of Plant Breeders Rights. …”
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Bouvard et Pécuchet et le ruban de Möbius. Variation mathématique sur le désir by Florence Pellegrini

“…Complementary, antithetical but harmonic, the childless widower and the bachelor resolve the solitude of their lives in this providential encounter which mates them for good: a two-headed protagonist, Bouvard and Pécuchet form an inseparable entity that functions with cross-references, connections, inverted symmetry. …”
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Digital Current Measurement Element for Operation During Current Transformer Severe Saturation by Yu. V. Rumiantsev, F. A. Romaniuk, V. Yu. Rumiantsev, I. V. Novash

“…To solve this problem, it is proposed to form the output signal of the digital current measurement element in depending on the input signal total harmonic distortion (THD) coefficient value. Moreover, it is worthwhile to form the output signal so that for a low CT saturation conditions this output signal slightly differs from the secondary current RMS value, and for a severe CT saturation conditions it exceeds this value. …”
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Diffusion Maps Clustering for Magnetic Resonance Q-Ball Imaging Segmentation by Demian Wassermann, Maxime Descoteaux, Rachid Deriche

“…In this paper, we use a spherical harmonic ODF representation as input to the diffusion maps clustering method. …”
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Directions for improving the legal regulation of forensic DNA analysis in Ukraine in the context of integration into the European Union by R. L. Stepaniuk, V. V. Kikinchuk

“…Together with the adoption of the Law of Ukraine “On the State Registration of Human Genomic Information”, it is necessary to introduce changes and additions to the Code of Criminal Procedure of Ukraine in order to harmonize the provisions of these normative legal acts, which primarily concern the improvement of the procedure for obtaining samples for molecular genetic research. …”
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The Commercial Determinants of Nonalcoholic Beer: Redemption, Revenue, or Men’s Harm Reduction? by John L. Oliffe, Nina Gao, Mary T. Kelly, Trevor Goodyear, Murray Drummond, Christine Levesque, Katherine White

“…For example, in Canada, NAB is exempt from alcoholic beer excise duty but considered beer for the goods and services and harmonized sales taxes. Coupled with industry production costs and profit margins, these taxes contribute to NAB and alcoholic beer retail price parity. …”
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Translation and Validation for the Portuguese Population of the Bedside Handover Attitudes and Behaviors Questionnaire by Cruchinho P, López-Franco MD, Teixeira G, Lucas P, Gaspar F

“…The questionnaire was cross-culturally adapted through translation, translation synthesis, and back-translation procedures, an expert committee harmonization, and two pre-tests.Results: We obtained one factorial solution through exploratory factor analysis that explained 53.5% of the total variance, with 18 items distributed by four components: Direct Engagement, Personal Interaction, Information Sharing, and Individualized Approach. …”
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Economic Diplomacy of the Russian Federation: Prospects for the Development of an Eff ective Export Support System by A. A. Naryshkin

“…The author concludes that for the eff ective functioning of this system, it is necessary to harmonize the work and activities of its institutions. …”
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ReLTER: An R interface for environmental observation in long term ecological research by Alessandro Oggioni, Micha Silver, Paolo Tagliolato, Arnon Karnieli

“…More than forty functions have been implemented that allow the retrieval of species occurrence data from third-party online networks, such as GBIF, iNaturalist, and OBIS, as well as earth observation images from various internet archives, and to harmonize the downloaded data (in terms of structure, semantics, taxonomy, etc.) for combining and linking them in subsequent analyses. …”
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Socio-Economic Challenges for the Urban Ecosystem: Complex Model of Smart Tourism and Infrastructure by Gevorg Orbelyan

“…The ultimate goal is to position Yerevan as a pioneering example of how smart infrastructure and tourism can harmonize within an urban ecosystem, creating a thriving, forward-looking city adaptable to evolving demands. …”
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Respiratory Virus Vaccines: Pathways to Recommendations and Enhanced Coverage for At-Risk Populations by Stefania Maggi, Odile Launay, Rachel Dawson

“…Potential strategies to overcome these barriers and improve uptake include strengthening and harmonizing immunization guidelines and improving respiratory disease surveillance systems to appropriately identify needs and direct resources. …”
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