Regulatory T cell-like response to SARS-CoV-2 in Jamaican fruit bats (Artibeus jamaicensis) transduced with human ACE2. by Bradly Burke, Savannah M Rocha, Shijun Zhan, Miles Eckley, Clara Reasoner, Amin Addetia, Juliette Lewis, Anna Fagre, Phillida A Charley, Juergen A Richt, Susan R Weiss, Ronald B Tjalkens, David Veesler, Tawfik Aboellail, Tony Schountz

“…CD4+ helper T cells became activated upon ex vivo recall stimulation with SARS-CoV-2 nucleocapsid peptide library and exhibited elevated mRNA expression of the regulatory T cell cytokines interleukin-10 and transforming growth factor-β, which may have limited inflammatory pathology. …”
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Inhibition of Glutamine Uptake Improves the Efficacy of Cetuximab on Gastric Cancer by Huanrong Ma PhD, Jingjing Wu Bachelor, Minyu Zhou PhD, Jianhua Wu PhD, Zhenzhen Wu PhD, Li Lin PhD, Na Huang PhD, Wangjun Liao PhD, Li Sun PhD

“…Treatment for advanced gastric cancer is challenging. Epidermal growth factor receptor (EGFR) contributes to the proliferation and development of gastric cancer (GC), and its overexpression is associated with unfavorable prognosis in GC. …”
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Chlamydia trachomatis Growth and Cytokine mRNA Response in a Prostate Cancer Cell Line by Ivan M. Petyaev, Naylia A. Zigangirova, Elena Y. Morgunova, Nigel H. Kyle, Elena D. Fedina, Yuriy K. Bashmakov

“…Furthermore, propagation of C. trachomatis in CWR-R1 cells leads to enhanced transcription of interleukin-6 and fibroblast growth factor-2, genes encoding two important proinflammatory cytokines implicated in the molecular mechanisms of chemoresistance of prostate cancer and its ability to metastasize. …”
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Screening and Functional Pathway Analysis of Pulmonary Genes Associated with Suppression of Allergic Airway Inflammation by Adipose Stem Cell-Derived Extracellular Vesicles by Sung-Dong Kim, Shin Ae Kang, Yong-Wan Kim, Hak Sun Yu, Kyu-Sup Cho, Hwan-Jung Roh

“…Expression of paraoxonase 1 (PON1), brain-expressed X-linked 2 (Bex2), insulin-like growth factor binding protein 6 (Igfbp6), formyl peptide receptor 1 (Fpr1), and secretoglobin family 1C member 1 (Scgb1c1) was significantly increased in asthmatic mice following treatment with ASC-derived EVs. …”
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Swallowing-related muscle inflammation and fibrosis induced by a single dose of radiation exposure in mice by Shuntaro Soejima, Chia-Hsien Wu, Haruna Matsuse, Mariko Terakado, Shinji Okano, Tsuyoshi Inoue, Yoshihiko Kumai

“…Results Compared to control mice, those treated with 20-Gy, but not 6.7-Gy, irradiation had significantly increased tumor necrosis factor-α (TNF-α) (p < 0.01) and α-smooth muscle actin (αSMA) (p < 0.05) expression at 10 days and significantly increased expression levels of motif chemokine ligand-2 (CCL2), α-SMA, tumor growth factor-β1 (TGF-β1), type1 collagen, and interleukin-1β (IL-1β) (p < 0.05) in the muscles at 1 month by real-time PCR analysis. …”
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Association between Visual Acuity and Retinal Layer Metrics in Diabetics with and without Macular Edema by LakshmiPriya Rangaraju, Xuejuan Jiang, J. Jason McAnany, Michael R. Tan, Justin Wanek, Norman P. Blair, Jennifer I. Lim, Mahnaz Shahidi

“…In subjects without DME, increased INL thickness was associated with reduced VA, whereas in subjects without DME but with previous antivascular endothelium growth factor treatment, thickening of OPL was associated with reduced VA. …”
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Proliferin-1 Ameliorates Cardiotoxin-Related Skeletal Muscle Repair in Mice by Hiroki Goto, Aiko Inoue, Limei Piao, Lina Hu, Zhe Huang, Xiangkun Meng, Yusuke Suzuki, Hiroyuki Umegaki, Masafumi Kuzuya, Xian Wu Cheng

“…We recently demonstrated that proliferin-1 (PLF-1) functions as an apoptotic cell-derived growth factor and plays an important role in vascular pathobiology. …”
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Prognostic values of intracellular cell-related genes in esophageal cancer and their regulatory mechanisms by Wei Cao, Dacheng Jin, Weirun Min, Haochi Li, Rong Wang, Jinlong Zhang, Yunjiu Gou

“…Stepwise multivariate Cox analysis pinpointed three prognostic genes: androgen receptor (AR), C-X-C motif chemokine ligand 8 (CXCL8), and epidermal growth factor receptor (EGFR). The risk model’s applicability was confirmed in the GSE53624 dataset, revealing eight significantly different immune-related gene sets. …”
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Inhibition of miR-182-5p Targets FGF9 to Alleviate Osteoarthritis by Yang Sun, Sanmao Su, Mengjun Li, Ang Deng

“…Methods. miR-182-5p and fibroblast growth factor 9 (FGF9) were overexpressed or knocked down in IL-1β-induced chondrocytes. …”
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Network Pharmacology Combined With Metabolomics Reveals the Mechanism of Yangxuerongjin Pill Against Type 2 Diabetic Peripheral Neuropathy in Rats by Jin R, Pei H, Yue F, Zhang X, Zhang Z, Xu Y, Li J

“…YXRJP can prolong the TWL, increase the MNCV of the sciatic nerve, alleviate the injury of the sciatic nerve, reduce the levels of triglyceride (TG), improve the expression of Insulin-like growth factor 1 (IGF-1) protein in the sciatic nerve, and reduce the expression of protein kinase B (AKT) protein. …”
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Egfr Amplification Specific Gene Expression in Phyllodes Tumours of the Breast by Konstantin Agelopoulos, Christian Kersting, Eberhard Korsching, Hartmut Schmidt, Arno Kuijper, Christian August, Pia Wülfing, Joke Tio, Werner Boecker, Paul J. van Diest, Burkhard Brandt, Horst Buerger

“…Background: Recently, we were able to show that amplifications of the epidermal growth factor receptor (egfr) gene and the overexpression of EGFR were associated with the initiation and progression of phyllodes tumours. …”
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Isolation and Evaluation of Potential Use of Prebiotics—Utilizing Butyrate-Producing Bacteria in Nibea coibor by Zhongzhen Li, Ngoc Tuan Tran, Ming Zhang, Zhaoxi Li, Wanying Yang, Shuqi Wang, Zhong Hu, Shengkang Li

“…Compared to control, levels of complement C3, complement C4, immunoglobulin M (IgM), transforming growth factor-β (TGF-β), interleukin (IL)-10, IL-1β, and lysozyme (LZM) increased, while malondialdehyde (MDA) decreased in treated groups. …”
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One-Year Outcomes in Subjects Developing Macular Neovascularization While Undergoing Avacincaptad Pegol Therapy for Geographic Atrophy by Rush RB, Klein W, Rush SW, Reinauer R

“…Subjects were divided into 1) a Study Group of patients who developed MNV and then underwent anti-vascular endothelial growth factor (VEGF) therapy during the study period, and 2) a Control Group of patients who were complication-free during the study period. …”
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PropAngio study protocol: a neoadjuvant trial on the efficacy of propranolol monotherapy in cutaneous angiosarcoma—a proof of principle study by Neeltje Steeghs, Jos H Beijnen, Kimberley M Heinhuis, Nikki S IJzerman, Anne Miek Koenen, Winette T A van der Graaf, Rick L Haas, Alwin D R Huitema, Winan J van Houdt

“…Angiosarcoma has several similarities with haemangioma, including its high β-adrenergic receptor expression and the supposedly important role of vascular endothelial growth factor in malignant growth. As a result, propranolol has been administered small scale in individual angiosarcoma cases with promising results. …”
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تأثیر فعالیت ورزشی حاد و مزمن در شرایط هایپوکسی بر مقادیر گردش خونی فاکتور رشد اندوتلیال عروقی: مروری نظام‌مند و فراتحلیل... by محمد جواد پوروقار, موسی خلفی

“…مقاله مروری مقدمه: هدف فراتحلیل حاضر، مقایسه‌ی تأثیر تمرین حاد و مزمن در شرایط هایپوکسی در برابر نورموکسی بر فاکتور رشد اندوتلیال عروقی (Vascular endothelial growth factor) VEGF می‌باشد. روش‌ها: جستجوی جامع در پایگاه‌های اطلاعاتی PubMed، Web of Science و Scopus برای پیدا کردن مطالعات اصیل از زمان شروع تا تاریخ 30/01/1403انجام صورت گرفت. …”
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Preclinical studies of the falnidamol as a highly potent and specific active ABCB1 transporter inhibitor by Baojie Liu, Yongzheng Lu, Ruihui Lin, Junbao Xu, Zilin Shang, Xinyu Hou, Xulong Shao, Zhifang Pan, Tao Yu, Weiguo Feng

“…Falnidamol, a tyrosine kinase inhibitor (TKI) targeting the epidermal growth factor receptor (EGFR), is currently in phase 1 clinical trials for the treatment of solid tumors. …”
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Pooled Multicenter Safety Analysis of Lupin’s Intravitreal Biosimilar Ranibizumab (Ranieyes) in Chorioretinal Vascular Diseases by Debdulal Chakraborty, Tushar Kanti Sinha, Sourav Sinha, Aniruddha Maiti, Angshuman Mukherjee, Krishnendu Nandi, Sudipta Das, Saptorshi Majumdar, Dinesh Rungta, Ranabir Bhattacharya

“…Conclusions This large-scale, real-world study demonstrates that Ranieyes is a safe intravitreal antivascular endothelial growth factor (anti-VEGF) agent across various chorioretinal vascular diseases. …”
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The Association of Retinal Disease with Vision Impairment and Functional Status in Medicare Patients by Vincent Garmo, Xiaohui Zhao, Carmen D. Ng, Aimee Near, Tania Banerji, Keiko Wada, Gary Oderda, Diana Brixner, Joseph Biskupiak, Ferhina S. Ali, Archad M. Khanani, Alicia Menezes, Ibrahim M. Abbass

“…**Conclusions:** Patients with nAMD continue to experience more vision impairment and worse functional status compared with a similar population of Medicare beneficiaries despite availability of therapies like antivascular endothelial growth factor to treat retinal disease.…”
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Clinical Comparative Study of Intravitreal Injection of Triamcinolone Acetonide and Aflibercept in the Treatment of Diabetic Retinopathy Cystoid Macular Edema by Yanxia Zhu, Jun Li, Songping Yu, Bangxun Mao, Jia Ying

“…The clinical curative effect, visual acuity, central subfield macular thickness (CSMT), macular volume, scores of quality of life, and levels of cytokines in aqueous humor (vascular endothelial growth factor (VEGF), monocyte chemoattractant protein-1 (MCP-1), human angiopoietin-like protein 4 (ANGPTL4)] at different time points (before and at 6 months after surgery) were compared between the two groups. …”
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Positive Expression of IGFBP2 as a Novel Prognostic Biomarker for Patients with Lower-Grade Gliomas by Yanguo Li, Jiawei Fan, Zhuo Shen, Jun Zhang, Xuemei Yin, Fang Han, Wenfei Li

“…Background: Previous studies have identified insulin-like growth factor-binding protein 2 (IGFBP2) as a target gene associated with the prognosis of various malignant cancers. …”
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