Mechanistic insights into the role of traditional Chinese medicine in treating gastric cancer by Ziqiang Chen, Ting Yu, Yunhe Wang, Jiaxin Li, Bo Zhang, Liya Zhou

“…We examine how TCM suppresses angiogenesis by targeting the vascular endothelial growth factor (VEGF) and cyclooxygenase-2 (COX-2) pathways, effectively starving tumors of nutrients and oxygen required for growth and metastasis. …”
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Adipose-Derived Stem Cells Alleviate Radiation-Induced Muscular Fibrosis by Suppressing the Expression of TGF-β1 by Wei Sun, Xinchu Ni, Suping Sun, Leiming Cai, Jingping Yu, Jian Wang, Bin Nie, Zhiqiang Sun, Xinye Ni, Xiufeng Cao

“…Significant decrease was noted in the integrated optimal density of the transforming growth factor β1 (TGF-β1) in the ASCs group compared with those of PBS group at 4 w, 8 w, and 26 w after irradiation. …”
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Plasma levels of immunosuppressive mediators during cardiopulmonary bypass by E. Borrelli, P. Giomarelli, A. Naldini, E. Luzzi, S. Silvestri, M. Gardinali, V. Bocci

“…The aim of this study was to evaluate plasma levels of two mediators with immunosuppressive properties, complement fraction C3a (C3a) and transforming growth factor-β1 (TGF-β1), during extracorporeal circulation. …”
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Comparative transcriptomic and metabolomics analysis of ovary in Nilaparvata lugens after trehalase inhibition by Yongkang Liu, Fan Yang, Sijing Wan, Xianzhong Wang, Liwen Guan, Yan Li, Caidi Xu, Binghua Xie, Shigui Wang, Xiao-Ling Tan, Bin Tang

“…The overlapping DEGs were implicated in various biological processes, including protein metabolism, fatty acid metabolism, AMPK signaling, mTOR signaling, insulin/insulin-like growth factor signaling (IIS), the tricarboxylic acid (TCA) cycle, oxidative phosphorylation, and the cellular process of meiosis in oocytes. …”
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Comparative Evaluation of Bone Repair with Four Different Bone Substitutes in Critical Size Defects by Gustavo Grossi-Oliveira, Leonardo P. Faverani, Bruno Coelho Mendes, Tárik Ocon Braga Polo, Gabriel Cury Batista Mendes, Valthierre Nunes de Lima, Paulo Domingos Ribeiro Júnior, Roberta Okamoto, Osvaldo Magro-Filho

“…Immunohistochemical analysis for Runt-related transcription factor 2 (Runx2), vascular endothelial growth factor (VEGF), and osteocalcin (OC) was performed. …”
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Detection of Estrogen Receptor Status in Breast Cancer Cytology Samples by an Optical Nanosensor by Pooja V. Gaikwad, Nazifa Rahman, Pratyusha Ghosh, Dianna L. Ng, Ryan M. Williams

“…Estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2) are the primary biomarkers which inform breast cancer treatment. …”
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Toll-Like Receptor 4 in Bone Marrow-Derived Cells Contributes to the Progression of Diabetic Retinopathy by Hui Wang, Haojun Shi, Jing Zhang, Guoliang Wang, Jinxiang Zhang, Fagang Jiang, Qing Xiao

“…TLR4 mutation did not block the occurrence of high blood glucose after STZ injection compared with WT mice but did alleviate the progression of DR and alter the expression of the small vessel proliferation-related genes, vascular endothelial growth factor (VEGF), and hypoxia inducible factor-1α (HIF-1α). …”
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Synergistic Effects of Cabozantinib and EGFR-Specific CAR-NK-92 Cells in Renal Cell Carcinoma by Qing Zhang, Kang Tian, Jinjing Xu, Haixu Zhang, Liantao Li, Qiang Fu, Dafei Chai, Huizhong Li, Junnian Zheng

“…We developed an epidermal growth factor- (EGFR-) specific third-generation CAR. …”
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Vitamin C exerts anti-cadmium induced fracture functions/targets: bioinformatic and biostructural findings by Rong Li, Songzuo Yu, Xiao Liang, Yu Li, Keng Po Lai

“…Nine core targets were characterized, including tumor protein p53, epidermal growth factor receptor, proto-oncogene c, mitogen-activated protein kinase-1 (MAPK1), MAPK3, signal transducer and activator of transcription-3, MAPK14, prostaglandin-endoperoxide synthase 2, and estrogen receptor alpha. …”
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Unhealthy Phenotype as Indicated by Salivary Biomarkers: Glucose, Insulin, VEGF-A, and IL-12p70 in Obese Kuwaiti Adolescents by Mor-Li Hartman, J. Max Goodson, Ping Shi, Jorel Vargas, Tina Yaskell, Danielle Stephens, Maryann Cugini, Hatice Hasturk, Roula Barake, Osama Alsmadi, Sabiha Al-Mutawa, Jitendra Ariga, Pramod Soparkar, Jawad Behbehani, Kazem Behbehani, Francine Welty

“…Elevated salivary glucose and insulin occurring together was associated with elevated vascular endothelial growth factor and reduced salivary interleukin-12. Conclusion. …”
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A versatile gold leaf immunosensor with a novel surface functionalization strategy based on protein L and trastuzumab for HER2 detection by Ivana Kundacina, Silvia Schobesberger, Stefan Kittler, Helena Thumfart, Oliver Spadiut, Peter Ertl, Nikola Ž. Knežević, Vasa Radonic

“…In this study, a cost-effective biosensor for detecting human epidermal growth factor receptor 2 (HER2) was developed using custom-made gold leaf electrodes (GLEs). …”
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Potassium Current Signature of Neuronal/Glial Progenitors in Amniotic Fluid Stem Cells by Paola Sabbatini, Sabrina Cipriani, Andrea Biagini, Luana Sallicandro, Cataldo Arcuri, Rita Romani, Paolo Prontera, Alessandra Mirarchi, Rosaria Gentile, Diletta Del Bianco, Elko Gliozheni, Sandro Gerli, Irene Giardina, Maurizio Arduini, Alessandro Favilli, Antonio Malvasi, Andrea Tinelli, Bernard Fioretti

“…AF-SCs, when subcultured in the presence of basic Fibroblast Growth Factor (bFGF), have been shown to survive and migrate when transplanted into the striatum of the rat brain, exhibiting behavior characteristics of neuronal/glial progenitor cells. …”
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Feasibility of Ex Vivo Ligandomics by Prabuddha Waduge, Remya Ammassam Veettil, Bojun Zhang, Chengchi Huang, Hong Tian, Wei Li

“…We quantified the binding of clonal phages displaying Scg3 and vascular endothelial growth factor (VEGF), confirming that their binding patterns to isolated diabetic versus healthy ECs matched in vivo patterns. …”
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Relationship between VEGF to PEDF ratio and in-hospital mortality in acute respiratory distress syndrome patients by Qifeng Luo, Ningning Shen, Jingtian Liang, Xichun Qin, Shoujie Feng, Yuting Chen, Lei Xu

“…Moreover, statistically significant differences were observed in the levels of vascular endothelial growth factor (VEGF) and pigment epithelium-derived factor (PEDF) between the two groups. …”
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Endocrinopathies after Allogeneic and Autologous Transplantation of Hematopoietic Stem Cells by Francesco Orio, Giovanna Muscogiuri, Stefano Palomba, Bianca Serio, Mariarosaria Sessa, Valentina Giudice, Idalucia Ferrara, Libuse Tauchmanovà, Annamaria Colao, Carmine Selleri

“…Dysfunctions of the hypothalamus-pituitary-growth hormone/insulin growth factor-I axis, hypothalamus-pituitary-thyroid axis, and hypothalamus-pituitary-adrenal axis were documented as later complicances, occurring in about 10, 30, and 40–50% of transplanted patients, respectively. …”
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IGF-1R Inhibition Suppresses Cell Proliferation and Increases Radiosensitivity in Nasopharyngeal Carcinoma Cells by Zhe Wang, Guangyan Liu, Jiwei Mao, Min Xie, Ming Zhao, Xuefen Guo, Shanshan Liang, Heming Li, Xuefeng Li, Ruoyu Wang

“…Although ionizing radiation (IR) has provided considerable improvements in nasopharyngeal carcinoma (NPC) treatment, radioresistance is still a major threat for some subsets of patients. The insulin-like growth factor-1 receptor (IGF-1R) signaling pathway is tightly regulated and plays critical roles in mediating cell proliferation, growth, and survival. …”
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The roles of pleiotrophin in brain injuries: a narrative review of the literature by Yupeng Lei, Ruixi Zhou, Qian Mao, Xia Qiu, Dezhi Mu

“…Background Pleiotrophin (PTN), a secreted multifunctional growth factor, is highly expressed in the developing brain. …”
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Expression of HGF and c-Met Proteins in Human Keratoconus Corneas by Jingjing You, Li Wen, Athena Roufas, Chris Hodge, Gerard Sutton, Michele C. Madigan

“…Recent genetic studies indicate that gene variants of an inflammation-related molecule, hepatocyte growth factor (HGF), are associated with an increased susceptibility for developing KC. …”
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Early Activation of Pulmonary TGF-β1/Smad2 Signaling in Mice with Acute Pancreatitis-Associated Acute Lung Injury by Hamid Akbarshahi, Asha Sam, Chaolei Chen, Ann H. Rosendahl, Roland Andersson

“…There is no specific therapy directed at underlying pathophysiological mechanisms for acute lung injury. Transforming growth factor-β (TGF-β) is involved in the resolution of lung injury in later phases of the disease. …”
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The Antiseptic Octenidine Inhibits Langerhans Cell Activation and Modulates Cytokine Expression upon Superficial Wounding with Tape Stripping by Nenad Nikolić, Philip Kienzl, Pooja Tajpara, Martin Vierhapper, Johannes Matiasek, Adelheid Elbe-Bürger

“…Furthermore, OCT reduced both pro- and anti-inflammatory mediators (IL-8, IL-33, and IL-10), while angiogenesis and growth factor mediators (VEGF and TGF-β1) remained unchanged in skin explant cultures. …”
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